Apoptosis
Los inhibidores de la apoptosis son compuestos que previenen o retrasan el proceso de muerte celular programada, conocido como apoptosis. Estos inhibidores son vitales para estudiar los mecanismos de supervivencia celular y se utilizan para investigar enfermedades donde la apoptosis está desregulada, como el cáncer, los trastornos neurodegenerativos y las enfermedades autoinmunes. Al modular la apoptosis, estos inhibidores pueden ayudar en el desarrollo de terapias dirigidas a controlar la muerte celular. En CymitQuimica, ofrecemos una amplia selección de inhibidores de la apoptosis de alta calidad para apoyar su investigación en biología celular, oncología y campos relacionados.
Subcategorías de "Apoptosis"
- ASK(9 productos)
- BCL(11 productos)
- Caspasa(142 productos)
- FOXO1(3 productos)
- IAP(67 productos)
- Mdm2(12 productos)
- PD-1 / PD-L1(138 productos)
- PDK(9 productos)
- PERK(25 productos)
- Serina / treonina quinasa(14 productos)
- Survivin(14 productos)
- TNF(89 productos)
- c-RET(56 productos)
- p53(63 productos)
Mostrar 6 subcategorías más
Se han encontrado 5903 productos de "Apoptosis"
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TAI-95
CAS:TAI-95 is an inhibitor of highly expressed cancer protein 1 (Hec1).Fórmula:C24H23N5O3S2Forma y color:SolidPeso molecular:493.60Silvestrol
CAS:Silvestrol is a eukaryotic translation initiation factor 4A inhibitor. Silvestrol causes autophagy and caspase-mediated apoptosis.Fórmula:C34H38O13Pureza:98%Forma y color:SolidPeso molecular:654.66Thalidomide-NH-C5-NH2
CAS:Thalidomide-NH-C5-NH2 is a synthetic E3 ligase ligand-linker conjugate, consisting of a Thalidomide-based cereblon ligand and a linker, used in the synthesis of PROTACs.Fórmula:C18H22N4O4Peso molecular:358.39N-a-Tosyl-L-lysinyl-chloromethylketone hydrochloride
CAS:N-a-Tosyl-L-lysinyl-chloromethylketone hydrochloride (TLCK hydrochloride) is an irreversible serine protease inhibitor that functions by alkylating the histidine residue at the active site, thus inhibiting trypsin and trypsin-like proteases. It effectively inhibits caspase-3, caspase-6, and caspase-7 with IC50 values of 12.0, 54.5, and 19.3 μM, respectively. Additionally, N-a-Tosyl-L-lysinyl-chloromethylketone hydrochloride induces apoptosis in HL-60 cells and prevents the reduction of mitochondrial transmembrane potential during the apoptosis process.Fórmula:C14H22Cl2N2O3SPeso molecular:369.31TP-030-1
CAS:TP-030-1, RIPK1 inhibitor: K(i) hRIPK1 at 3.9nM, IC50 mRIPK1 at 4.2μM; targets inflammation, neurodegeneration research.Fórmula:C23H22N4O3Forma y color:SolidPeso molecular:402.45Triphen diol
CAS:Triphen diol, a phenol diol, fights pancreatic cancer & cholangiocarcinoma, inducing apoptosis via caspase-dependent & -independent paths.Fórmula:C22H20O4Forma y color:SolidPeso molecular:348.39ASCT2-IN-1
CAS:ASCT2-IN-1 (compound 20k) is an inhibitor of ASCT2, demonstrating IC50 values of 5.6 μM in A549 cells and 3.5 μM in HEK293 cells. It induces apoptosis and inhibits tumor growth.Fórmula:C36H32Cl2N2O4Peso molecular:627.56Lometrexol hydrate
CAS:Lometrexol hydrate, an antipurine antifolate, inhibits GARFT and purine synthesis, leading to cancer cell apoptosis without causing DNA breaks.Fórmula:C21H27N5O7Forma y color:SolidPeso molecular:461.475ADH-6
CAS:<p>ADH-6, a tripyridylamide, disrupts mutant p53 aggregates in cancer cells, reviving its function and inducing apoptosis.</p>Fórmula:C29H36N8O9Forma y color:SolidPeso molecular:640.64YCW-E11
CAS:<p>YCW-E11 is an antiapoptotic Bcl-2 family proteins inhibitor.</p>Fórmula:C25H21Cl2N3O6S2Pureza:98%Forma y color:SolidPeso molecular:594.49MDK-3345
CAS:MDK-3345 is a reversible covalent inhibitor for Mcl-1.Fórmula:C36H34BN3O7Pureza:98%Forma y color:SolidPeso molecular:631.48VEGFR-2-IN-15
VEGFR-2-IN-15 (Compound 14b) is a potent inhibitor of VEGFR-2. VEGFR-2-IN-15 inhibits the growth of HepG2 cells in the Pre-G1 phase and induces apoptosis.Fórmula:C23H18ClN3O4SForma y color:SolidPeso molecular:467.92Sabialimon P
CAS:<p>Sabialimon P (compound 16), with an IC50 of 18.12 μM, functions as a NO release inhibitor and exhibits anti-inflammatory properties. It effectively diminishes the secretion of TNF-α, iNOS, IL-6, and NF-κB, and suppresses the expression of COX-2 and NF-κB/p65 in LPS-induced RAW264.7 cells.</p>Fórmula:C31H50O4Forma y color:SolidPeso molecular:486.73PKM2 modulator 2
CAS:<p>PKM2 modulator 2 (compound C599) is a potent inhibitor of PKM2, displaying antiproliferative activity and inducing apoptosis. This compound holds potential for research in glioblastoma.</p>Fórmula:C21H13FN4O3Forma y color:SolidPeso molecular:388.351Apoptosis inducer 36
CAS:<p>Apoptosisinducer 36 (Compound 42) exhibits anti-leukemic activity by reducing leukemia stem cells (LSC) and inducing differentiation. It inhibits proliferation of AML cells by causing cell cycle arrest in the G1 phase, and induces PANoptosis, which includes apoptosis, pyroptosis, and necrosis.</p>Fórmula:C23H40O3SiForma y color:SolidPeso molecular:392.647EMT inhibitor-3
CAS:<p>EMT inhibitor-3 (compound 11i) is an epithelial-mesenchymal transition (EMT) inhibitor that effectively suppresses the proliferation, migration, and invasion of SK-N-SH neuroblastoma cells, with an IC50 value of 2.5 μM. It induces mitochondrial-mediated intrinsic apoptosis in tumor cells by enhancing the Bax/Bcl-2 protein expression ratio, promoting the release of cytochrome C from mitochondria, and activating caspase 9 and caspase 3. EMT inhibitor-3 is applicable for cancer research.</p>Fórmula:C29H21F2N3O4SeForma y color:SolidPeso molecular:592.45p38 MAPK-IN-3
<p>Compound 2c is a potent p38α MAPK inhibitor with antitumor effects, enhancing apoptosis and ROS.</p>Fórmula:C22H17BrO2Forma y color:SolidPeso molecular:393.2706:0 PE
CAS:06:0 PE (PE(6:0/6:0)) is a water-soluble phospholipid characterized by its short acyl chains. It possesses notable antitumor activity and can inhibit tumor progression in the body. Additionally, it exhibits antiproliferative and pro-apoptotic properties, and serves as a precursor for phosphatidylcholine and phosphatidylethanolamine.Fórmula:C17H34NO8PForma y color:SolidPeso molecular:411.43HDL-16
CAS:HDL-16 is a highly effective P2Y14R antagonist with anti-colitis effects, targeting P2Y14R in intestinal epithelial cells to alleviate ulcerative colitis.Fórmula:C14H11BrN2OPureza:97.58%Forma y color:SolidPeso molecular:303.15Elocalcitol
CAS:Elocalcitol is a calcitriol analog for inhibition of prostate cell growth.Fórmula:C29H43FO2Forma y color:SolidPeso molecular:442.65
