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Apoptosis

Apoptosis

Los inhibidores de la apoptosis son compuestos que previenen o retrasan el proceso de muerte celular programada, conocido como apoptosis. Estos inhibidores son vitales para estudiar los mecanismos de supervivencia celular y se utilizan para investigar enfermedades donde la apoptosis está desregulada, como el cáncer, los trastornos neurodegenerativos y las enfermedades autoinmunes. Al modular la apoptosis, estos inhibidores pueden ayudar en el desarrollo de terapias dirigidas a controlar la muerte celular. En CymitQuimica, ofrecemos una amplia selección de inhibidores de la apoptosis de alta calidad para apoyar su investigación en biología celular, oncología y campos relacionados.

Subcategorías de "Apoptosis"

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Se han encontrado 5618 productos de "Apoptosis"

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  • Thalidomide-NH-PEG2-COOH

    CAS:
    <p>Thalidomide-NH-PEG2-COOH: a synthesized E3 ligase ligand-linker with cereblon ligand and PROTAC linker.</p>
    Fórmula:C20H23N3O8
    Forma y color:Solid
    Peso molecular:433.417
  • EGFR-IN-83


    <p>EGFR-IN-83 (Compound 9), an EGFR inhibitor with an IC50 of 2.53 nM, exhibits antiproliferative effects on MCF-7 and MDA-MB-231 cell lines, with respective IC50</p>
    Fórmula:C22H17F3N4O
    Pureza:98%
    Forma y color:Solid
    Peso molecular:410.39
  • ABBV-167

    CAS:
    <p>ABBV-167 is a phosphate prodrug of the BCL-2 inhibitor venetoclax.</p>
    Fórmula:C46H53ClN7O11PS
    Forma y color:Solid
    Peso molecular:978.45
  • PROTAC EGFR degrader 6

    CAS:
    <p>PROTAC EGFR degrader 6 effectively degrades EGFR Del19 in HCC827 cells (DC50=45.2 nM) and induces apoptosis and G1 arrest.</p>
    Fórmula:C49H57FN12O5
    Forma y color:Solid
    Peso molecular:913.05
  • CYP51/PD-L1-IN-2


    <p>CYP51/PD-L1-IN-2 (compound L20), a quinazoline with antifungal properties, is a potent dual inhibitor targeting both CYP51 (IC50: 0.263 μM) and PD-L1 (IC50: 0.</p>
    Fórmula:C25H23N7O3
    Forma y color:Solid
    Peso molecular:469.5
  • Violacein

    CAS:
    <p>Violacein, a purple antibacterial and antiprotozoal compound from C. violaceum, effective against Gram-positive bacteria and P. falciparum.</p>
    Fórmula:C20H13N3O3
    Forma y color:Solid
    Peso molecular:343.34
  • Stem bromelain

    CAS:
    <p>Stem bromelain: cysteine protease from pineapple stem with fibrinolytic, anti-inflammatory, antitumoral properties.</p>
    Forma y color:Solid
  • Citreoviridin

    CAS:
    <p>Citreoviridin from Penicillium citreoviride blocks brain Na+/K+-ATPase; boosts Na+/K+- and Mg2+-ATPase in microsomes dose-dependently.</p>
    Fórmula:C23H30O6
    Pureza:98%
    Forma y color:Solid
    Peso molecular:402.48
  • Fosbretabulin [free base]

    CAS:
    <p>Fosbretabulin is a natural cis-stilbene that interferes with cellular tubulin dynamics and selectively destroys tumor blood vessels.</p>
    Fórmula:C18H21O8P
    Forma y color:Solid
    Peso molecular:396.33
  • FLT3-IN-21


    <p>FLT3-IN-21 (compound LC-3), a potent FLT3 inhibitor with an IC50 value of 8.4 nM, induces apoptosis and arrests the cell cycle in the G1 phase.</p>
    Fórmula:C20H22FN5O2
    Forma y color:Solid
    Peso molecular:383.42
  • (R)-JAK2/STAT3-IN-10a

    CAS:
    <p>(R)-JAK2/STAT3-IN-10a is the R-isomer of JAK2/STAT3-IN-1.JAK2/STAT3-IN-1 is a structural domain inhibitor of GP130 D1 with antitumor activity.</p>
    Fórmula:C34H35BrF3N5O2
    Pureza:97.99%
    Forma y color:Soild
    Peso molecular:682.57
  • Pomstafib-2

    CAS:
    <p>Pomstafib-2, a potent and selective inhibitor of STAT5b, reduces pSTAT5b expression and effectively induces apoptosis [1] [2].</p>
    Fórmula:C52H66N2O20P2
    Forma y color:Solid
    Peso molecular:1101.03
  • PROTAC Mcl1 degrader-1

    CAS:
    <p>PROTAC Mcl1 degrader-1 is a Cereblon ligand-based targeted chimeric protein degrader (PROTAC) and an Mcl-1 inhibitor, useful in cancer research.</p>
    Fórmula:C45H45BrN6O8S
    Pureza:98.74%
    Forma y color:Solid
    Peso molecular:909.84
  • Lacto-N-fucopentaose I

    CAS:
    <p>Lacto-N-fucopentaose I is a milk oligosaccharide.</p>
    Fórmula:C32H55NO25
    Forma y color:Solid
    Peso molecular:853.774
  • Thalidomide-O-C8-COOH

    CAS:
    <p>Thalidomide-O-C8-COOH, also known as Cereblon ligand 3, is a Thalidomide-derived compound that serves as a Cereblon (CRBN) ligand for the targeted recruitment</p>
    Fórmula:C22H26N2O7
    Forma y color:Solid
    Peso molecular:430.45
  • DB2313

    CAS:
    <p>DB2313 is a potent PU.1 inhibitor (IC50=14 nM) that disrupts gene binding, induces AML cell apoptosis, and has anticancer properties.</p>
    Fórmula:C42H41FN8O2
    Pureza:98.63% - 99.29%
    Forma y color:Solid
    Peso molecular:708.83
  • ChoKα inhibitor-3


    <p>ChoKα Inhibitor-3, a sulfur-containing choline kinase inhibitor, effectively inhibits HChoK α1 with an IC50 value of 0.66 μM and possesses the capability to</p>
    Fórmula:C50H54Br2Cl2N4S2
    Forma y color:Solid
    Peso molecular:1005.83
  • Calcimycin hemimagnesium

    CAS:
    <p>Calcimycin hemimagnesium is an antibiotic, ionophore, and ATPase inhibitor that boosts intracellular Ca2+, causing cell death and apoptosis.</p>
    Fórmula:C58H72MgN6O12
    Forma y color:Solid
    Peso molecular:1069.53
  • Solanidine

    CAS:
    <p>Solanidine is a cholestane alkaloid isolated from potato species with antitumor effects. Solanidine inhibits proliferation.</p>
    Fórmula:C27H43NO
    Pureza:96.83%
    Forma y color:Solid
    Peso molecular:397.64
  • Dehydrobruceine B

    CAS:
    <p>Dehydrobruceine B, from Brucea javanica, enhances Cisplatin-induced apoptosis by affecting AIF, Bax, and Keap1-Nrf2.</p>
    Fórmula:C23H26O11
    Forma y color:Solid
    Peso molecular:478.45