Apoptosis
Los inhibidores de la apoptosis son compuestos que previenen o retrasan el proceso de muerte celular programada, conocido como apoptosis. Estos inhibidores son vitales para estudiar los mecanismos de supervivencia celular y se utilizan para investigar enfermedades donde la apoptosis está desregulada, como el cáncer, los trastornos neurodegenerativos y las enfermedades autoinmunes. Al modular la apoptosis, estos inhibidores pueden ayudar en el desarrollo de terapias dirigidas a controlar la muerte celular. En CymitQuimica, ofrecemos una amplia selección de inhibidores de la apoptosis de alta calidad para apoyar su investigación en biología celular, oncología y campos relacionados.
Subcategorías de "Apoptosis"
- ASK(6 productos)
- BCL(11 productos)
- Caspasa(127 productos)
- FOXO1(3 productos)
- IAP(66 productos)
- Mdm2(12 productos)
- PD-1 / PD-L1(126 productos)
- PDK(9 productos)
- PERK(23 productos)
- Serina / treonina quinasa(15 productos)
- Survivin(13 productos)
- TNF(91 productos)
- c-RET(51 productos)
- p53(62 productos)
Mostrar 6 subcategorías más
Se han encontrado 5618 productos de "Apoptosis"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
5-Fluorouracil-13C,15N2
CAS:<p>5-Fluorouracil-13C,15N2 is a standard for quantifying 5-fluorouracil via GC/LC-MS and blocks DNA synthesis, causing cell apoptosis.</p>Fórmula:C4H3FN2O2Forma y color:SolidPeso molecular:133.057(D)-PPA 1 TFA
<p>(D)-PPA 1 TFA is a hydrolysis-resistant D-peptide antagonist and a potent PD-1/PD-L1 inhibitor, exhibiting an affinity for PD-1 of 0.51 μM and demonstrating</p>Fórmula:C72H99F3N20O23Pureza:98%Forma y color:SolidPeso molecular:1669.67PROTAC Bcl-xL degrader-2
<p>PROTAC Bcl-xL degrader-2, based on von Hippel-Lindau ligand, is a potent degrader of Bcl-xL (a Bcl-2 family member), demonstrating an IC 50 of 0.6 nM.</p>Fórmula:C68H80N8O14S3Forma y color:SolidPeso molecular:1329.6CDK2-IN-45
<p>CDK2-IN-45 is a CDK2 inhibitor with an IC50 value of 0.64 μM. It effectively inhibits the proliferation of DU-145 and PC-3 cell lines, with IC50 values of 2.20 μM and 4.17 μM, respectively. Additionally, CDK2-IN-45 induces G0/G1 phase cell cycle arrest and apoptosis. It is utilized in prostate cancer research.</p>Fórmula:C25H16ClN5SForma y color:SolidPeso molecular:453.95RIPK1-IN-17
CAS:<p>RIPK1-IN-17 is a dual inhibitor of RIPK1 and RIPK3 inhibits necrosis by inhibiting phosphorylation of RIPK1, RIPK3 and MLKL,in a tnf-induced inflammation model.</p>Fórmula:C26H19F4N3O3SPureza:95.22%Forma y color:SolidPeso molecular:529.51β-Apopicropodophyllin
CAS:<p>β-Apopicropodophyllin, a natural product isolated from Hyptis wticillata, promotes apoptosis through mechanisms including microtubule disruption, DNA damage,</p>Fórmula:C22H20O7Forma y color:SolidPeso molecular:396.39Tubulin/AKT1-IN-1
<p>Tubulin/AKT1-IN-1 (Compound D1-1) serves as an inhibitor of both tubulin polymerization and AKT pathway activation, effectively suppressing proliferation and</p>Fórmula:C38H34ClNO11Pureza:98%Forma y color:SolidPeso molecular:716.13Liensinine Perchlorate
CAS:<p>Liensinine is the active constituent of plumula nelambinis with anti-hypertension.</p>Fórmula:C37H43ClN2O10Pureza:99.80%Forma y color:SolidPeso molecular:711.2N-Acetylpsychosine
CAS:<p>N-Acetylpsychosine, also known as α-galactosylated C2-ceramide (d18:1/2:0), exhibits immunostimulatory properties.</p>Fórmula:C26H49NO8Forma y color:SolidPeso molecular:503.67MRT-2359
CAS:<p>"MRT-2359: Oral GSPT1 reducer, anti-cancer, targets NSCLC/SCLC, effective on MYC-driven cells."</p>Fórmula:C22H17F4N3O6Pureza:98.69%Forma y color:SoildPeso molecular:495.38Anticancer agent 154
<p>Anticancer agent 154 (Compound 8h) enhances reactive oxygen species production, causing mitochondrial damage, and promotes cell apoptosis and DNA damage.</p>Fórmula:C22H23N5O2Pureza:98%Forma y color:SolidPeso molecular:389.45H3B-8800
CAS:<p>H3B-8800 is an SF3B1 modulator that can be used to study transfusion-dependent anemia.</p>Fórmula:C31H45N3O6Pureza:98.31%Forma y color:SoildPeso molecular:555.71YCH3124
<p>YCH3124 (compound Z33) is an inhibitor of USP7, exhibiting anti-tumor activity with an IC50 value of 41.9 nM. This compound demonstrates substantial in vitro anti-proliferative effects on various tumor cells, including LNCaP (IC50= 3.6 nM) and CHP-212 (IC50=9.9 nM). Moreover, YCH3124 induces apoptosis in CHP-212 cells by disrupting the cell cycle process during the G1 phase.</p>Fórmula:C30H34N4O5Forma y color:SolidPeso molecular:530.61XZ739
CAS:XZ739: Cereblon-based PROTAC, degrades BCL-XL (DC50 2.5 nM in MOLT-4, 16hr), induces caspase apoptosis.Fórmula:C65H76ClF3N8O12S3Forma y color:SolidPeso molecular:1349.99RSM3 TFA
<p>RSM3 TFA is a stapled peptide and an inhibitor of METTL3-METTL14, exhibiting a dissociation constant (Kd) of 3.10 μM. It inhibits tumor growth and induces cell apoptosis. RSM3 TFA is utilized in cancer research.</p>Forma y color:Odour SolidNC-R17
<p>NC-R17, an RSL3-based noncovalent GPX4 degrader implicated in ferroptosis, demonstrates anti-tumor activity and is utilized in the design of noncovalent GPX4-</p>Fórmula:C53H67N7O7Pureza:98%Forma y color:SolidPeso molecular:914.14Acrixolimab
CAS:<p>Acrixolimab is a humanized IgG4-κ monoclonal antibody that selectively targets PD-1 [1] [2].</p>Pureza:98%Forma y color:LiquidAntibiotic DC 81
CAS:<p>DC 81: Streptomyces-derived antitumor antibiotic, potent nucleic acid synthesis inhibitor, binds DNA sequences, forms covalent adducts.</p>Fórmula:C13H14N2O3Forma y color:SolidPeso molecular:246.26Mcl1-IN-26
CAS:<p>Mcl1-IN-26 is an effective and selective myeloid cell leukemia 1 inhibitor.</p>Fórmula:C45H52ClN5O6SForma y color:SolidPeso molecular:826.44Antitumor agent-41
<p>Antitumor Agent-41 (Compound N-12) exhibits potent antitumor properties, demonstrating significant antimigration and anti-invasion activities.</p>Fórmula:C64H109IN2O21Forma y color:SolidPeso molecular:1369.46
