Apoptosis
Los inhibidores de la apoptosis son compuestos que previenen o retrasan el proceso de muerte celular programada, conocido como apoptosis. Estos inhibidores son vitales para estudiar los mecanismos de supervivencia celular y se utilizan para investigar enfermedades donde la apoptosis está desregulada, como el cáncer, los trastornos neurodegenerativos y las enfermedades autoinmunes. Al modular la apoptosis, estos inhibidores pueden ayudar en el desarrollo de terapias dirigidas a controlar la muerte celular. En CymitQuimica, ofrecemos una amplia selección de inhibidores de la apoptosis de alta calidad para apoyar su investigación en biología celular, oncología y campos relacionados.
Subcategorías de "Apoptosis"
- ASK(6 productos)
- BCL(11 productos)
- Caspasa(125 productos)
- FOXO1(3 productos)
- IAP(66 productos)
- Mdm2(12 productos)
- PD-1 / PD-L1(125 productos)
- PDK(9 productos)
- PERK(25 productos)
- Serina / treonina quinasa(15 productos)
- Survivin(13 productos)
- TNF(92 productos)
- c-RET(51 productos)
- p53(62 productos)
Mostrar 6 subcategorías más
Se han encontrado 5600 productos de "Apoptosis"
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HDAC6-IN-16
<p>HDAC6-IN-16 (compound 5c), a quinazolin-4(3H)-one-based inhibitor of histone deacetylase 6 (HDAC6), demonstrates an anticancer effect by inhibiting colony</p>Fórmula:C23H19N3O3SPureza:98%Forma y color:SolidPeso molecular:417.48CPD-10
CAS:<p>CPD-10 is a potent bifunctional PROTAC degrader targeting CCND1 and CDK4 and exhibits antiproliferative effects. It induces apoptosis and reduces the protein expression of Cyclin D1, Cyclin D3, CDK4, and P-Rb(5807/811) in a dose-dependent manner.</p>Fórmula:C46H61N15O4Forma y color:SolidPeso molecular:888.08PD0166285 dihydrochloride
CAS:<p>PD-166285 is an effective and broadly active inhibitor of protein tyrosine kinase.</p>Fórmula:C26H29Cl4N5O2Forma y color:SolidPeso molecular:585.35TAT-NEP1-40 acetate
<p>TAT-NEP1-40 acetate, a potential therapeutic for axonal regeneration and functional recovery post-stroke, safeguards PC12 cells from oxygen and glucose</p>Fórmula:C268H438N88O77·xC2H4O2Pureza:98%Forma y color:SolidPeso molecular:6124.89 (free base)MG-277
<p>MG-277 is a molecular glue compound transformed from PROTAC degradation agent, MG-277 potently inhibits tumor cell growth in a p53-independent manner.</p>Fórmula:C41H42Cl2FN5O5Pureza:98%Forma y color:SolidPeso molecular:774.71Thalidomide 4'-oxyacetamide-alkyl-C2-amine HCl
CAS:<p>Thalidomide 4'-oxyacetamide-alkyl-C2-amine HCl is an E3 ligase ligand-linker conjugate containing the E3 ubiquitin ligase cereblon (CRBN) and linker.</p>Fórmula:C17H19ClN4O6Pureza:99.78%Forma y color:SolidPeso molecular:410.81Apoptosis inducer 33
<p>Apoptosisinducer 33 (compound H2) is a hydrazone derivative. It exhibits antioxidant and antimicrobial properties, capable of inhibiting the growth of Staphylococcus aureus, Escherichia coli, and Candida albicans. Additionally, Apoptosisinducer 33 can suppress tumor cell proliferation and induce apoptosis (apoptosis), making it useful for tumor research.</p>Fórmula:C16H13N3O2Forma y color:SolidPeso molecular:279.293Bcl-xL antagonist 2
CAS:<p>Bcl-xL antagonist 2 is an effective and selective antagonist of Bcl-xL with an IC50 of 91 nM and a Ki of 65 nM.</p>Fórmula:C21H16N4O3S2Pureza:99.81%Forma y color:SolidPeso molecular:436.51JAK/HDAC-IN-2
<p>JAK/HDAC-IN-2, a potent 2-amino-4-phenylaminopyrimidine dual-target inhibitor, effectively suppresses JAK1/2 and HDAC3/6 at nanomolar concentrations.</p>Fórmula:C28H38N6O5SPureza:98%Forma y color:SolidPeso molecular:570.7Thalidomide-O-C6-NH2
CAS:<p>Thalidomide-O-C6-NH2 is a synthesized E3 ligase ligand-linker conjugate used in the PROTAC dTAG-13, a degrader of FKBP12F36V and BET[1].</p>Fórmula:C19H23N3O5Pureza:98%Forma y color:SolidPeso molecular:373.4HDAC6-IN-22
<p>HDAC6-IN-22 (compound 30), an HDAC6 inhibitor, exhibits an IC50 of 4.63 nM and demonstrates antiproliferative effects against multiple myeloma both in vitro and</p>Fórmula:C24H24N4O2Pureza:98%Forma y color:SolidPeso molecular:400.47RET ligand-3
<p>RETligand-3 is the ligand for PROTAC QZ2135, which targets RET.</p>Fórmula:C38H42N10O3Forma y color:SolidPeso molecular:686.81(±)-Enterodiol
CAS:<p>"(±)-Enterodiol, the racemate of Enterodiol, is metabolized from lignans found in whole-grain cereals, nuts, legumes, flaxseed, and vegetables by human intestinal bacteria. This compound exhibits apoptotic effects in colorectal cancer (CRC) cells and has been identified to possess anti-cancer activities [1] [2]."</p>Fórmula:C18H22O4Forma y color:SolidPeso molecular:302.36Verdinexor
CAS:<p>Verdinexor (KPT-335) (KPT-335), a specific XPO1/CRM1 inhibitor, are orally bioavailable.</p>Fórmula:C18H12F6N6OPureza:98% - 99.68%Forma y color:SolidPeso molecular:442.32HTR2A antagonist 1
<p>HTR2A antagonist 1 (Compound 15f) is an HTR2A antagonist with an IC50 of 42.79 nM. It induces sub-G1 cell cycle arrest and apoptosis in colorectal cancer cells by activating the p53/p21/caspase 3 signaling pathway. HTR2A antagonist 1 exhibits good liver microsomal stability and is useful for colorectal cancer research.</p>Fórmula:C35H43Cl2F2N5O4Forma y color:SolidPeso molecular:706.65NQO2-IN-1
CAS:<p>NQO2-IN-1, a resveratrol analog, is a potent NQO2 inhibito,antitumor,generation of ROS and up-regulation of DR5 (death receptor 5) to promote apoptosis.</p>Fórmula:C18H18N2O3Pureza:99.83%Forma y color:SoildPeso molecular:310.35IC 86621
CAS:<p>IC 86621: DNA-PK ATP-competitive inhibitor, IC50 120 nM, enhances DSB antitumor effects, EC50 68 µM for repair.</p>Fórmula:C12H15NO3Pureza:99.68%Forma y color:SolidPeso molecular:221.25APG-1387
CAS:<p>APG-1387 inhibits IAPs, degrades cIAP1/2, XIAP, boosts chemosensitivity, and induces apoptosis in NPC.</p>Fórmula:C60H72N10O10S2Forma y color:SolidPeso molecular:1157.41Cholicamideβ
<p>Cholicamideβ (compound 6), a self-assembling small molecule cancer vaccine adjuvant, forms low cytotoxicity virus-like particles and upon binding to peptide</p>Fórmula:C55H94N2O6Pureza:98%Forma y color:SolidPeso molecular:879.34SC-2001
CAS:<p>SC-2001 inhibits MCL-1 and STAT3, enhances SHP-1, induces apoptosis in breast cancer, and counters STAT3-driven sorafenib resistance in liver cancer.</p>Fórmula:C18H14BrN3OPureza:98%Forma y color:SolidPeso molecular:368.23
