Apoptosis
Los inhibidores de la apoptosis son compuestos que previenen o retrasan el proceso de muerte celular programada, conocido como apoptosis. Estos inhibidores son vitales para estudiar los mecanismos de supervivencia celular y se utilizan para investigar enfermedades donde la apoptosis está desregulada, como el cáncer, los trastornos neurodegenerativos y las enfermedades autoinmunes. Al modular la apoptosis, estos inhibidores pueden ayudar en el desarrollo de terapias dirigidas a controlar la muerte celular. En CymitQuimica, ofrecemos una amplia selección de inhibidores de la apoptosis de alta calidad para apoyar su investigación en biología celular, oncología y campos relacionados.
Subcategorías de "Apoptosis"
- ASK(9 productos)
- BCL(11 productos)
- Caspasa(142 productos)
- FOXO1(3 productos)
- IAP(67 productos)
- Mdm2(12 productos)
- PD-1 / PD-L1(138 productos)
- PDK(9 productos)
- PERK(25 productos)
- Serina / treonina quinasa(14 productos)
- Survivin(14 productos)
- TNF(89 productos)
- c-RET(56 productos)
- p53(63 productos)
Mostrar 6 subcategorías más
Se han encontrado 5903 productos de "Apoptosis"
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RTX-002
RTX-002 is a human monoclonal antibody (mAb) targeting PDCD1/PD-1/CD279. This compound is applicable in the research of autoimmune diseases such as systemic lupus erythematosus and multiple sclerosis.Forma y color:Odour LiquidAZD5582 dihydrochloride
CAS:<p>Dimeric Smac mimetic inhibits XIAP, cIAP1/2 (IC50: 15/15/21 nM); binds BIR3 domain; degrades cIAPs; induces apoptosis in cancer cells; shrinks tumors in mice.</p>Fórmula:C58H80Cl2N8O8Forma y color:SolidPeso molecular:1088.23OPBP-1
<p>OPBP-1 is a D-peptide developed through phage display screening, molecular docking, and molecular dynamics simulations. It exhibits high stability, strong antitumor activity, and oral bioavailability. OPBP-1 selectively binds to the PD-L1 protein, significantly blocking the interaction between PD-1 and PD-L1, which helps restore and enhance T lymphocyte function while reducing the proportion of myeloid-derived suppressor cells (MDSCs), counteracting tumor-induced immune evasion. OPBP-1 is applicable for research in cancer immunotherapy.</p>Fórmula:C64H92N20O19SPeso molecular:1476.65683Antitumor agent-41
Antitumor Agent-41 (Compound N-12) exhibits potent antitumor properties, demonstrating significant antimigration and anti-invasion activities.Fórmula:C64H109IN2O21Forma y color:SolidPeso molecular:1369.46ATPase-IN-3
CAS:ATPase-IN-3 is an ATPase (ATPase) inhibitor that can be used in the study of metabolism-related diseases.Fórmula:C10H6N2O3S2Pureza:97.76%Forma y color:SoildPeso molecular:266.3Verproside
CAS:Verproside is a useful organic compound for research related to life sciences. The catalog number is T124745 and the CAS number is 50932-20-2.Fórmula:C22H26O13Forma y color:SolidPeso molecular:498.437Golimumab
CAS:Golimumab (CNTO-148), an anti-TNFα IgG1κ monoclonal antibody with anti-inflammatory and anti-cancer activity, can be used to prevent inflammation and cartilage.Forma y color:LiquidPeso molecular:146.93 kDaRIP1-IN-1
<p>RIP1-IN-1 is an orally bioavailable RIP1 inhibitor with a high binding affinity (Kd: 110 nM). This compound exhibits significant activity against necroptosis and effectively suppresses necrosome formation by inhibiting the phosphorylation of RIP1, RIP3, and MLKL pathways. RIP1-IN-1 can inhibit necroptosis and is applicable in research on acute liver injury.</p>Forma y color:Odour SolidMcl1-IN-12
CAS:<p>Mcl1-IN-12 has anti-tumor activity.It is a selective Mcl-1 inhibitor, less potent at Bcl-2, with Kis of 0.29 and 3.1 μM, respectively.</p>Fórmula:C45H46N4O6S2Pureza:98%Forma y color:SolidPeso molecular:803Topoisomerase I/II inhibitor 6
TopoisomeraseI/II inhibitor 6 (compound 3i) acts as an effective inhibitor of topoisomerase I and II, with IC50 values of 4.77 µM and 15 µM, respectively. Additionally, it exhibits antiproliferative activity against the human melanoma cell line LOX IMVI, demonstrating IC50 values of 26.7 µM and 25.4 µM.Fórmula:C31H28F2N4O6SForma y color:SolidPeso molecular:622.64Vonlerolizumab
CAS:<p>Vonlerolizumab (MOXR 0916) is a humanized IgG OX40 agonist monoclonal antibody with potential in cancer and immune disease research.</p>Pureza:SDS-PAGE:97.3%;SEC-HPLC:99.4%Forma y color:LiquidPeso molecular:145.25 kDaMG-277
MG-277 is a molecular glue compound transformed from PROTAC degradation agent, MG-277 potently inhibits tumor cell growth in a p53-independent manner.Fórmula:C41H42Cl2FN5O5Pureza:98%Forma y color:SolidPeso molecular:774.71ARI-1
ARI-1 is a receptor tyrosine kinase-like orphan receptor 1 (ROR1) inhibitor that binds to ROR1's extracellular Frizzled domain, effectively inhibiting aberrantForma y color:Odour SolidFerroptosis-IN-14
Ferroptosis-IN-14 (compund 36) exhibits the most potent anti-ferroptotic activity with an EC50 value of 0.58 ± 0.02 μM, demonstrating excellent anti-ferroptotic efficacy, as well as stability in microsomes and plasma.Forma y color:Odour SolidMDM2 ligand 4
<p>MDM2ligand 4 is a ligand of MDM2 and can be used in the synthesis of the PROTAC degrader [KT-253].</p>Fórmula:C31H33Cl2FN2O4Forma y color:SolidPeso molecular:587.509PERK-IN-4
CAS:PERK-IN-4 is a potent and selective PERK inhibitor with an IC50 value of 0.3 nM.PERK-IN-4 can be used in the study of cancer and neurological disorders.Fórmula:C24H19F4N5OPureza:99.44% - 99.49%Forma y color:SolidPeso molecular:469.43PD-1-IN-20
PD-1-IN-20 is the less active enantiomer of PD-1-IN-1.Fórmula:C12H20N6O7Pureza:98%Forma y color:SolidPeso molecular:360.32Ianalumab
CAS:<p>Ianalumab (VAY-736) is a decarboxylated humanized antibody against BAFF-R.</p>Pureza:100% (SEC-HPLC) - > 95%Forma y color:LiquidPeso molecular:146.44 kDaTNF-α-IN-11
<p>TNF-α-IN-11 (Compound 10) is a TNF-α inhibitor exhibiting a dissociation constant (K D) of 12.06 μM.</p>Fórmula:C24H26N2O5Forma y color:SolidPeso molecular:422.47LL-K9-3
CAS:LL-K9-3, a selective hydrophobic tagging technology (HyT)-based degrader, specifically targets the CDK9-cyclin T1 complex, displaying DC50 values of 589 nM forFórmula:C31H49N5O6S3Forma y color:SolidPeso molecular:683.94
