Apoptosis
Los inhibidores de la apoptosis son compuestos que previenen o retrasan el proceso de muerte celular programada, conocido como apoptosis. Estos inhibidores son vitales para estudiar los mecanismos de supervivencia celular y se utilizan para investigar enfermedades donde la apoptosis está desregulada, como el cáncer, los trastornos neurodegenerativos y las enfermedades autoinmunes. Al modular la apoptosis, estos inhibidores pueden ayudar en el desarrollo de terapias dirigidas a controlar la muerte celular. En CymitQuimica, ofrecemos una amplia selección de inhibidores de la apoptosis de alta calidad para apoyar su investigación en biología celular, oncología y campos relacionados.
Subcategorías de "Apoptosis"
- ASK(9 productos)
- BCL(11 productos)
- Caspasa(144 productos)
- FOXO1(3 productos)
- IAP(67 productos)
- Mdm2(12 productos)
- PD-1 / PD-L1(139 productos)
- PDK(9 productos)
- PERK(26 productos)
- Serina / treonina quinasa(18 productos)
- Survivin(14 productos)
- TNF(93 productos)
- c-RET(62 productos)
- p53(63 productos)
Mostrar 6 subcategorías más
Se han encontrado 6070 productos de "Apoptosis"
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Antiproliferative agent-25
Antiproliferative Agent-25 (Compound 3s4) is a selective PRMT5 inhibitor displaying an IC50 of 0.11 μM.Fórmula:C20H21BrN2O2Pureza:98%Forma y color:SolidPeso molecular:401.3PROTAC Bcl-xL degrader-1
PROTAC Bcl-xL degrader-1 targets Bcl-xL & IAP E3 ligases, degrades Bcl-xL, toxic to human platelets & MyLa 1929 (IC50: 62 nM, 8.5 μM).Fórmula:C76H96ClF3N10O11S3Forma y color:SolidPeso molecular:1514.28RO7567132
RO7567132 is a bispecific antibody that binds and agonizes LTBR bivalently while binds and antagonizes FAP monovalently, inducing the formation of local TLS.Forma y color:Odour LiquidAntimycin A2c
Anticancer Agent 141 (Compound AE), an antimycin alkaloid, exhibits inhibitory potential against HPV-infected cervical cancer.Fórmula:C28H40N2O9Pureza:98%Forma y color:SolidPeso molecular:548.63Didocosahexaenoin
CAS:Didocosahexaenoin, omega-3 diglyceride, disrupts mitochondria, induces ROS, apoptosis, and is cytotoxic to prostate cancer cells.Fórmula:C25H40O5Forma y color:SolidPeso molecular:420.58QZ2135
<p>QZ2135 (compound 20) is a PROTAC degrader that specifically targets RET and exhibits antitumor activity in vivo within a Ba/F3-KIF5B-RET-G810C xenograft mouse model. The compound demonstrates degradation activity with DC50 values of 4.7 nM (WT), 17.2 nM (V804M), and 73.8 nM (G810C) when targeting KIF5B-RET. QZ2135 is composed of the target protein ligand (red part) RETligand-3, the E3 ligase ligand (blue part) Lenalidomide-F, and the PROTAC Linker (black part) 7-Iodohept-1-yne, wherein the target protein ligand combined with the linker forms the conjugate RETLigand-Linker Conjugate-1.</p>Fórmula:C53H54N12O4Forma y color:SolidPeso molecular:923.07VB-85247
VB-85247 is a STING agonist that, by activating the STING pathway, induces the upregulation of inflammatory cytokines IFNα/β, TNFα, IL6, and CXCL10, as well as the maturation and activation of dendritic cells. It can lead to the regression of tumors within the bladder and is applicable in bladder cancer research.Forma y color:Odour SolidAnticancer agent 133
Compound Rh2 (Anticancer agent 133) is a cytotoxic and antimetastatic agent that induces cell cycle arrest, apoptosis, and autophagy.Fórmula:C24H19Cl3N5ORhPureza:98%Forma y color:SolidPeso molecular:602.71hMAO-B-IN-11
hMAO-B-IN-11 (Compound 12) is a selective and reversible inhibitor of human monoamine oxidase B (hMAO-B) with an IC50 value of 0.11 µM. It operates by competitively binding to the active site of hMAO-B, thereby preventing the oxidative deamination of monoamines and reducing hydrogen peroxide production. Additionally, hMAO-B-IN-11 inhibits pro-inflammatory mediators (NO, TNF-α, IL-1β) in activated microglia. This compound holds potential for research in neurodegenerative diseases such as Parkinson's and Alzheimer's.Forma y color:Odour SolidMcl-1 antagonist 1
CAS:Mcl-1 antagonist 1 is a Mcl-1 protein antagonist.Fórmula:C41H54ClF2N5O8SPureza:98%Forma y color:SolidPeso molecular:850.42VEGFR-2-IN-64
VEGFR-2-IN-64 (Compound 28) is an inhibitor of VEGFR2 with an IC50 of 27.8 nM. It suppresses the proliferation of cancer cells A549, T-47D, and Caco-2, exhibits anti-migration and anti-colony formation activities in T-47D cells, and induces apoptosis in T-47D cells.Fórmula:C72H123N9O6Forma y color:SolidPeso molecular:1210.8FLT3-IN-21
FLT3-IN-21 (compound LC-3), a potent FLT3 inhibitor with an IC50 value of 8.4 nM, induces apoptosis and arrests the cell cycle in the G1 phase.Fórmula:C20H22FN5O2Forma y color:SolidPeso molecular:383.42Caerin 1.1 TFA
Caerin 1.1 TFA, a host defense peptide derived from the Australian tree frog Litoria's glandular secretions, exhibits anti-proliferative effects on HeLa cellsPureza:98%Forma y color:Odour SolidTargaprimir-96
CAS:Targaprimir-96 is a potent microRNA-96 (miR-96) processing inhibitor.Fórmula:C77H102N18O7Pureza:98%Forma y color:SolidPeso molecular:1391.75Anti-Mouse PD-1 Antibody (D265A) Antibody (RMP1-14)
<p>Anti-Mouse PD-1 Antibody (D265A) is an IgG2a, κ antibody inhibitor derived from mice, specifically targeting mouse PD-1.</p>Forma y color:Odour LiquidThalidomide-Piperazine-PEG2-NH2
CAS:Thalidomide-Piperazine-PEG2-NH2 is a synthetic E3 ligase ligand-linker for PROTAC, combining cereblon ligand with a PEG2 linker.Fórmula:C23H31N5O6Forma y color:SolidPeso molecular:473.53SBP-0636457
CAS:SBP-0636457: SMAC mimetic, IAP inhibitor, binds BIR-domains (Ki=0.27μM), potential in tumor/cancer research.Fórmula:C25H36N4O4Forma y color:SolidPeso molecular:456.587Ferroptosis-IN-3
Ferroptosis-IN-3 (Compound 25), a ferroptosis inhibitor, demonstrates potent activity by inhibiting RSL3-induced ferroptosis in HT-1080 cells (EC50: 8.6 nM).Pureza:98%Forma y color:Odour SolidAspidin BB
CAS:Aspidin BB, a phloroglucinol from Dryopteris, inhibits cancer by causing cell cycle arrest and apoptosis in HO-8910 cells.Fórmula:C25H32O8Forma y color:SolidPeso molecular:460.52fac-[Re(CO)3(L6)(H2O)][NO3]
Compound 6, fac-[Re(CO)3(L6)(H2O)][NO3], a rhenium(I) tricarbonyl aqua complex, serves as an anticancer agent by disrupting mitochondrial function.Fórmula:C24H14N5O7ReSPureza:98%Forma y color:SolidPeso molecular:702.67
