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Apoptosis

Apoptosis

Los inhibidores de la apoptosis son compuestos que previenen o retrasan el proceso de muerte celular programada, conocido como apoptosis. Estos inhibidores son vitales para estudiar los mecanismos de supervivencia celular y se utilizan para investigar enfermedades donde la apoptosis está desregulada, como el cáncer, los trastornos neurodegenerativos y las enfermedades autoinmunes. Al modular la apoptosis, estos inhibidores pueden ayudar en el desarrollo de terapias dirigidas a controlar la muerte celular. En CymitQuimica, ofrecemos una amplia selección de inhibidores de la apoptosis de alta calidad para apoyar su investigación en biología celular, oncología y campos relacionados.

Subcategorías de "Apoptosis"

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Se han encontrado 5618 productos de "Apoptosis"

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  • A-385358

    CAS:
    A-385358 is a selective Bcl-xL inhibitor with Kis of 0.80 nM for Bcl-xL and 67 nM for Bcl-2, respectively.
    Fórmula:C32H41N5O5S2
    Pureza:99.97%
    Forma y color:Solid
    Peso molecular:639.83
  • CN128 hydrochloride

    CAS:
    <p>CN128 hydrochloride is an oral, selective hydroxypyridone iron chelator for β-thalassemia research.</p>
    Fórmula:C15H18ClNO3
    Forma y color:Solid
    Peso molecular:295.76
  • CAY10503

    CAS:
    <p>CAY10503: proapoptotic, anti-growth agent; arrests cell cycle at G0-G1; IC50 = 7-23 μM; induces HL60 differentiation in 72 hours.</p>
    Fórmula:C18H14O3
    Forma y color:Solid
    Peso molecular:278.3
  • n-Octyl caffeate

    CAS:
    <p>n-Octyl caffeate demonstrates anti-cancer and apoptosis-inducing properties in highly liver-metastatic murine colon 26-L5 carcinoma cell lines.</p>
    Fórmula:C17H24O4
    Forma y color:Solid
    Peso molecular:292.37
  • CAY10682

    CAS:
    <p>(±)-Nutlin-3 &amp; CAY10682 inhibit p53-Mdm2; CAY also blocks NF-κB, IKKs phosphorylation, and cancer cell growth (IC50s = 2-6 μM).</p>
    Fórmula:C30H25BrFN5O
    Forma y color:Solid
    Peso molecular:570.45
  • Tubulin inhibitor 23

    CAS:
    <p>Potent Tubulin inhibitor 23 (IC50: 4.8 μM) induces apoptosis and has dose-dependent antiangiogenic properties, promising for leukemia research.</p>
    Fórmula:C26H23NO6S
    Forma y color:Solid
    Peso molecular:477.53
  • ABT-100

    CAS:
    <p>ABT-100 is a potent, highly selective, and orally active farnesyl transferase inhibitor with broad-spectrum antitumor activity.</p>
    Fórmula:C27H19F3N4O3
    Pureza:98%
    Forma y color:Solid
    Peso molecular:504.46
  • PIK-C98

    CAS:
    <p>PIK-C98 is an inhibitor of PI3K that acts by displaying potent preclinical activity against multiple myeloma.</p>
    Fórmula:C16H10Cl2N2OS
    Pureza:98%
    Forma y color:Solid
    Peso molecular:349.23
  • ORY-1001 free base

    CAS:
    <p>ORY-1001: potent KDM1A inhibitor (IC50 &lt;20nM), selective, affects THP-1 cell gene regulation and apoptosis, hinders MV(4;11) cell growth (EC50 &lt;1nM).</p>
    Fórmula:C15H22N2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:230.35
  • PC-046

    CAS:
    <p>PC-046, a tubulin binder, targets DPC4/SMAD4-deficient tumors, inhibits growth in vitro, and is effective in SCID mice with high oral bioavailability (71%).</p>
    Fórmula:C22H18N2O3
    Forma y color:Solid
    Peso molecular:358.39
  • MX107

    CAS:
    <p>MX107 is a survivin inhibitor which induces degradation of XIAP and/or cIAP1, and suppresses genotoxic NF-kappaB activation.</p>
    Fórmula:C24H28N2O2
    Forma y color:Solid
    Peso molecular:376.49
  • HDAC-IN-51


    <p>HDAC-IN-51 is an HDAC inhibitor.</p>
    Fórmula:C27H24N4O2
    Pureza:97.19%
    Forma y color:Solid
    Peso molecular:436.51
  • HI5

    CAS:
    <p>HI5: potent tubulin/IDO inhibitor, IC50 70 nM (HeLa), blocks kynurenine, G2/M arrest, spurs T cell activity, &amp; triggers apoptosis.</p>
    Fórmula:C42H43N5O8
    Forma y color:Solid
    Peso molecular:745.82
  • Prexasertib mesylate

    CAS:
    Prexasertib (LY2606368), a Chk1/2 inhibitor, enhances therapy in acute lymphoblastic leukemia, causing DNA damage and antitumor effects.
    Fórmula:C19H23N7O5S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:461.49
  • PDPOB

    CAS:
    <p>PDPOB, a phenyl carboxylic acid derivative, may protect neurons from ischemic damage by reducing mitochondrial issues, oxidative stress, and cell death.</p>
    Fórmula:C15H20O5
    Forma y color:Solid
    Peso molecular:280.32
  • Tigilanol tiglate

    CAS:
    <p>Tigilanol tiglate (EBC-46) is a PKC/C1 domain activator. Tigilanol tiglate induces immunogenic cell death and tumour regression.</p>
    Fórmula:C30H42O10
    Pureza:98%
    Forma y color:Solid
    Peso molecular:562.65
  • Antitumor agent-62

    CAS:
    <p>Antitumor agent-62 releases NO, inhibits cancer cell growth, triggers apoptosis, and halts cell cycle at G2/M.</p>
    Fórmula:C21H19N3O9S
    Forma y color:Solid
    Peso molecular:489.46
  • Shield-2

    CAS:
    <p>Shield-2 is a potent FKBP-derived destabilizing domain stabilizing ligand.</p>
    Fórmula:C35H51N3O7
    Pureza:98%
    Forma y color:Solid
    Peso molecular:625.8
  • NSC 146109 hydrochloride

    CAS:
    <p>NSC 146109 hydrochloride is an activator of p53 targeting MDMX. NSC 146109 hydrochloride can be used for studies on breast cancer.</p>
    Fórmula:C17H17ClN2S
    Pureza:99.28%
    Forma y color:Solid
    Peso molecular:316.85
  • D-Cl-amidine

    CAS:
    <p>D-Cl-amidine is an effective and highly selective PAD1 inhibitor. D-Cl-amidine has a good correlation and no obvious toxicity.</p>
    Fórmula:C14H19ClN4O2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:310.78
  • Mitoguazone

    CAS:
    Mitoguazone is an antitumor agent, blocking SAM decarboxylase, disrupting polyamine synthesis, and hindering HIV DNA integration in immune cells.
    Fórmula:C5H12N8
    Pureza:97.47% - 98%
    Forma y color:Solid
    Peso molecular:184.2
  • ZDLD13

    CAS:
    <p>ZDLD13, a β-carboline, inhibits CDK4/CycD3, halts HCT116 tumor growth, and induces apoptosis with IC50=0.38μM.</p>
    Fórmula:C18H14N4O
    Forma y color:Solid
    Peso molecular:302.33
  • DRAK2-IN-1

    CAS:
    <p>Drak2-in-1: ATP-competitive DRAK2 inhibitor; IC50 = 3 nM, KI = 0.26 nM; affects DRAK1 (IC50 = 51 nM).</p>
    Fórmula:C21H20N4O3
    Forma y color:Solid
    Peso molecular:376.41
  • LSD1-IN-14

    CAS:
    <p>LSD1-IN-14: potent LSD1 inhibitor, IC50 0.89 μM; hinders A549/THP-1 cell growth, induces tumor cell apoptosis.</p>
    Fórmula:C21H24FN5
    Forma y color:Solid
    Peso molecular:365.45
  • AMG-548

    CAS:
    AMG-548, oral p38α inhibitor (Ki=0.5 nM), >1000x selectivity over p38γ/δ, blocks TNFα (IC50=3 nM), also inhibits Wnt/Casein kinase 1δ/ε.
    Fórmula:C29H27N5O
    Pureza:99.91%
    Forma y color:Solid
    Peso molecular:461.56
  • SMIP004

    CAS:
    <p>SMIP004 is an SKP2 E3 ligase inhibitor. SMIP004 is a cancer cell-selective apoptosis inducer of human prostate cancer cells.</p>
    Fórmula:C13H19NO
    Pureza:99.86%
    Forma y color:Solid
    Peso molecular:205.3
  • BJE6-106

    CAS:
    <p>BJE6-106 (B106) is a potent, selective PKCδ inhibitor (IC50: 0.05 μM) and targets selectivity over classical PKCα (IC50: 50 μM).</p>
    Fórmula:C26H23NO2
    Forma y color:Solid
    Peso molecular:381.47
  • SCH529074

    CAS:
    <p>SCH529074 is a selective activator of p53 (Ki = 1 μM) and can be used in studies about non-small-cell lung carcinoma.</p>
    Fórmula:C31H36Cl2N6
    Pureza:99.57%
    Forma y color:Solid
    Peso molecular:563.56
  • PARP1-IN-31

    CAS:
    <p>PARP1-IN-31 (compound 11f) is a PARP1 inhibitor with an IC₅₀ of 97 nM. It induces apoptosis and inhibits proliferation in lung cancer cell lines (e.g., A549).</p>
    Fórmula:C22H15ClFN3O2
    Pureza:98.99%
    Forma y color:Solid
    Peso molecular:407.83
  • Nafamostat hydrochloride

    CAS:
    <p>Nafamostat hydrochloride is a synthetic serine protease inhibitor and is an anticoagulant.</p>
    Fórmula:C19H19Cl2N5O2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:420.29
  • HSP90-IN-13

    CAS:
    <p>HSP90-IN-13 (5k): potent HSP90 inhibitor, IC50 25.07 nM, targets EGFR/VEGFR-2/Topo-2, blocks MCF-7 G2/M cycle, induces apoptosis.</p>
    Fórmula:C26H21N5O3S
    Forma y color:Solid
    Peso molecular:483.54
  • Antitumor agent-45

    CAS:
    <p>Antitumor agent-45 has an inhibitory effect on c-Met expression and is able to block A549 cells in the G0/G1 and G2/M phases and induce apoptosis.</p>
    Fórmula:C28H17BrFN5O3
    Forma y color:Solid
    Peso molecular:570.37
  • DRI-C25441

    CAS:
    <p>DRI-C25441 is a potent inhibitor of the CD40-CD40L interaction, exhibiting an IC50 value of 0.36 μM, and is capable of suppressing the immune response triggered</p>
    Fórmula:C31H21N3O6
    Forma y color:Solid
    Peso molecular:531.51
  • Mcl1-IN-1

    CAS:
    Mcl1-IN-1 is a myeloid cell factor 1 inhibitor (IC50=2.4 μM).
    Fórmula:C23H18ClN3O4
    Forma y color:Solid
    Peso molecular:435.86
  • Apoptosis inducer 10

    CAS:
    <p>Apoptosis inducer 10 is a potent apoptosis inducer with anti-proliferative activity.</p>
    Fórmula:C27H46N2O2
    Forma y color:Solid
    Peso molecular:430.67
  • Flunisolide hemihydrate

    CAS:
    <p>Flunisolide hemihydrate, a corticosteroid with anti-inflammatory properties, treats asthma and rhinitis by inducing eosinophil apoptosis.</p>
    Fórmula:C48H64F2O13
    Forma y color:Solid
    Peso molecular:887.024
  • IDH1 Inhibitor 9

    CAS:
    <p>IDH1 Inhibitor 9 (compound 11S) (2, 4, 8, 10 µM) induces apoptosis and causes cell cycle arrest in the S phase in a dose-dependent manner.</p>
    Fórmula:C26H30N4O3
    Forma y color:Solid
    Peso molecular:446.54
  • S65487

    CAS:
    <p>S65487 (VOB560) inhibits Bcl-2, including G101V and D103Y variants, while sparing MCL-1, BFL-1, and BCL-XL, supporting its anticancer potential.</p>
    Fórmula:C41H41ClN6O4
    Pureza:99.034%
    Forma y color:Solid
    Peso molecular:717.26
  • TNF-α-IN-10

    CAS:
    <p>TNF-α-IN-10 (compound 8a) acts as an inhibitor of IL-6 and TNF-α, demonstrating anti-inflammatory activity [1].</p>
    Fórmula:C17H14O4
    Forma y color:Solid
    Peso molecular:282.29
  • Clidanac

    CAS:
    Clidanac is a potent anti-inflammatory drug and is found to uncouple the oxidative phosphorylation.
    Fórmula:C16H19ClO2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:278.77
  • MBM-17S

    CAS:
    <p>MBM-17S, a potent NIMA-related kinase 2 (Nek2) inhibitor with an IC50 of 3 nM, effectively inhibits cancer cell proliferation by inducing cell cycle arrest and</p>
    Fórmula:C36H40N6O10
    Pureza:98%
    Forma y color:Solid
    Peso molecular:716.74
  • AMC-01

    CAS:
    <p>AMC-01 has potential antiviral activity and induces dose- and time-dependent inactivation of eIF2-α via phosphorylation of serine residue 51.</p>
    Fórmula:C27H27BrN2O6
    Pureza:99.95%
    Forma y color:Solid
    Peso molecular:555.42
  • 673-A

    CAS:
    <p>673-A inhibits ALDH1A, depletes ovarian CSCs, induces necroptosis, and reverses chemo resistance.</p>
    Fórmula:C15H13NO
    Forma y color:Solid
    Peso molecular:223.27
  • MPT0B392

    CAS:
    <p>MPT0B392 is an orally active quinoline derivative, induces c-Jun N-terminal kinase (JNK) activation.</p>
    Fórmula:C19H20N2O6S
    Forma y color:Solid
    Peso molecular:404.44
  • FW1256

    CAS:
    FW1256: phenyl analog, slow H2S donor, inhibits NF-κB, induces apoptosis, anti-inflammatory, potential cancer/cardio treatment.
    Fórmula:C12H10NOPS
    Forma y color:Solid
    Peso molecular:247.25
  • Epinephrine bitartrate

    CAS:
    <p>L-Epinephrine Bitartrate is alpha- and beta-adrenergic receptor stimulator.</p>
    Fórmula:C13H19NO9
    Pureza:98.6% - 99.07%
    Forma y color:White Solid
    Peso molecular:333.3
  • PD-1/PD-L1-IN-28

    CAS:
    <p>PD-1/PD-L1-IN-28, an inhibitor of the PD-1/PD-L1 signaling pathway (IC 50 = 0.744 µM), demonstrates promising research potential in tumor immunity.</p>
    Fórmula:C24H24N4O2
    Forma y color:Solid
    Peso molecular:400.47
  • HDACs/mTOR Inhibitor 1

    CAS:
    <p>HDACs/mTOR Inhibitor 1 is a dual HDACs and mammalian target of Rapamycin (mTOR) target inhibitor for treating hematologic malignancies (IC50s: 0.19 nM, 1.8 nM,</p>
    Fórmula:C28H38N8O5
    Forma y color:Solid
    Peso molecular:566.65
  • ACA-28

    CAS:
    <p>ACA-28 is an ERK MAPK signalling modulator that induces apoptosis in melanoma cells by overexpressing ERK.</p>
    Fórmula:C17H16O6
    Pureza:98.73%
    Forma y color:Solid
    Peso molecular:316.31
  • EGFR-IN-56

    CAS:
    <p>EGFR-IN-56 (13a) inhibits EGFR, EGFRT790M (IC50: 541.7nM), EGFRT790M/L858R (IC50: 132.1nM), blocks G2/M phase, and triggers apoptosis.</p>
    Fórmula:C23H22N4O3S
    Forma y color:Solid
    Peso molecular:434.51
  • Topoisomerase IIα-IN-3

    CAS:
    <p>Topoisomerase IIα-IN-3 is a DNA-inserting topoisomerase-Iiα inhibitor that blocks the cell cycle in G0/G1 phase and induces apoptosis.</p>
    Fórmula:C29H20N6O2S
    Forma y color:Solid
    Peso molecular:516.57
  • KY1022

    CAS:
    <p>KY1022 is a ras destabilizer. KY1022 targets the Wnt/ß-catenin pathway and inhibits development of metastatic colorectal cancer.</p>
    Fórmula:C17H19N3OS
    Forma y color:Solid
    Peso molecular:313.42
  • IDT

    CAS:
    <p>IDT, an oral TNFα modulator, changes neutrophil levels, boosts cognition, and reduces tau/amyloid in 3xTgAD mice.</p>
    Fórmula:C8H5NS2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:179.26
  • MBM-17

    CAS:
    <p>MBM-17 is a potent inhibitor of NIMA-related kinase 2 (Nek2,IC50 of 3 nM).</p>
    Fórmula:C28H28N6O2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:480.56
  • WK-298

    CAS:
    <p>WK-298 is an effective MDM2/MDMX-p53 interaction inhibitor.</p>
    Fórmula:C35H38Cl2N6O
    Pureza:98%
    Forma y color:Solid
    Peso molecular:629.62
  • TH1834 dihydrochloride

    CAS:
    <p>TH1834 dihydrochloride is a specific Tip60 histone acetyltransferase inhibitor.</p>
    Fórmula:C33H42Cl2N6O3
    Pureza:98%
    Forma y color:Solid
    Peso molecular:641.63
  • NSC-741909

    CAS:
    NSC-741909 is an anticancer agent that acts by suppressing the growth of several cell lines.
    Fórmula:C16H14ClNO
    Pureza:98%
    Forma y color:Solid
    Peso molecular:271.74
  • CPI-7c

    CAS:
    CPI-7c inhibits MDM2-p53 interaction and promotes MDM2 degradation.
    Fórmula:C22H18N2O3
    Pureza:98%
    Forma y color:Solid
    Peso molecular:358.39
  • RC-33 HCl

    CAS:
    <p>RC-33 HCl is a selective and metabolically stable σ1 receptor agonist potentiating NGF-induced neurite outgrowth.</p>
    Fórmula:C21H28ClN
    Pureza:98%
    Forma y color:Solid
    Peso molecular:329.91
  • SMBA2

    CAS:
    <p>SMBA2 is a Bax activator. It acts by specifically targeting the binding pocket at S184.</p>
    Fórmula:C8H16N4
    Pureza:98%
    Forma y color:Solid
    Peso molecular:168.24
  • D44

    CAS:
    <p>D44 is a Plasmodium FKBPs inhibitor.</p>
    Fórmula:C16H16N4OS
    Forma y color:Solid
    Peso molecular:312.39
  • MYRA-A

    CAS:
    <p>MYRA-A is an inducer of apoptosis in a Myc-dependent manner that acts by inhibiting Myc-driven transformation and disrupting MYC-Max interaction.</p>
    Fórmula:C19H20N2O4
    Pureza:98%
    Forma y color:Solid
    Peso molecular:340.37
  • W146 TFA

    CAS:
    <p>W146 TFA is a selective sphingosine-1-phosphate receptor 1 ( S1PR1 ) antagonist with an EC 50 value of 398 nM.</p>
    Fórmula:C18H28F3N2O6P
    Forma y color:Solid
    Peso molecular:456.399
  • GSK962

    CAS:
    <p>GSK962 is a GSK963 inactive enantiomer. It can be used to confirm the on-target effects.</p>
    Fórmula:C14H18N2O
    Pureza:99.75%
    Forma y color:Solid
    Peso molecular:230.31
  • DJ001

    CAS:
    <p>DJ001: specific PTPσ inhibitor, non-competitive, IC50=1.43 μM, aids hematopoietic stem cell regeneration.</p>
    Fórmula:C15H12N2O3
    Pureza:99.54%
    Forma y color:Solid
    Peso molecular:268.27
  • Dimethoate

    CAS:
    <p>Dimethoate (L-395) is a systemic and contact insecticide for control of cattle grubs and certain other insect pests of farm animals.</p>
    Fórmula:C5H12NO3PS2
    Pureza:99.74% - 99.91%
    Forma y color:White Crystalline Solid
    Peso molecular:229.26
  • MG-262

    CAS:
    <p>MG-262 is a reversible proteasome inhibitor with multiple biological activities [1] [2] [3].</p>
    Fórmula:C25H42BN3O6
    Forma y color:Solid
    Peso molecular:491.43
  • M199

    CAS:
    <p>M199, a novel inhibitor of TLR3/9 activation, induces secretion of IL-6, IL-8 and TNFalpha in human PBMCs.</p>
    Fórmula:C17H17N3O
    Pureza:98%
    Forma y color:Solid
    Peso molecular:279.34
  • DC-5163

    CAS:
    <p>DC-5163 inhibits GAPDH (IC50: 176.3 nM, Kd: 3.192 μM), targets cancer cell growth and glycolysis.</p>
    Fórmula:C18H20ClN3OS
    Pureza:98%
    Forma y color:Solid
    Peso molecular:361.89
  • K-7174 dihydrochloride

    CAS:
    <p>K-7174 dihydrochloride is a novel cell adhesion inhibitor; inhibits the expression of vascular cell adhesion molecule-1 (VCAM-1) induced by either IL-1β or TNF-</p>
    Fórmula:C33H50Cl2N2O6
    Pureza:99.15%
    Forma y color:Solid
    Peso molecular:641.67
  • (E)-[6]-Dehydroparadol

    CAS:
    <p>(E)-[6]-Dehydroparadol ((6)-Dehydroparadol), an oxidative metabolite of [6]-Shogaol, is a potent Nrf2 activator.</p>
    Fórmula:C17H24O3
    Pureza:99.85%
    Forma y color:Solid
    Peso molecular:276.37
  • RIPK1-IN-3

    CAS:
    <p>RIPK1-IN-3 is a RIPK1 inhibitor, with anti-inflammatory proprieties.</p>
    Fórmula:C22H19F3N6O3
    Pureza:98%
    Forma y color:Solid
    Peso molecular:472.42
  • BTK-IN-9

    CAS:
    <p>BTK-IN-9 reversibly inhibits BTK, disrupts mitochondria, boosts ROS, and triggers apoptosis in Z138 cells, impeding condyloma cell growth.</p>
    Fórmula:C25H19N7O4
    Forma y color:Solid
    Peso molecular:481.46
  • T-3256336

    CAS:
    <p>T-3256336 is an oral IAP blocker targeting cIAP-1, cIAP-2, and XIAP.</p>
    Fórmula:C31H45F2N5O5
    Pureza:98%
    Forma y color:Solid
    Peso molecular:605.72
  • AD-2646

    CAS:
    <p>AD-2646 has antidepressant activity and inhibits 2-deoxy-D-glucose (2-DG)-induced gastric acid secretion.</p>
    Fórmula:C23H40N2O4
    Forma y color:Solid
    Peso molecular:408.57
  • ABD56

    CAS:
    <p>ABD56 inhibits osteoclast formation and activity in vitro and in vivo.</p>
    Fórmula:C17H18O3
    Forma y color:Solid
    Peso molecular:270.32
  • Trehalose 6-behenate

    CAS:
    <p>Trehalose 6-behenate is a Th1/Th17 skewing vaccine adjuvant.</p>
    Fórmula:C34H64O12
    Pureza:98%
    Forma y color:Solid
    Peso molecular:664.86
  • PD-1/PD-L1-IN-14

    CAS:
    <p>PD-1/PD-L1-IN-14 (compound 17) is an inhibitor of PD-1/PD-L1 interaction (IC50=27.8 nM).</p>
    Fórmula:C24H24N4O2
    Forma y color:Solid
    Peso molecular:400.47
  • Tubulin/HDAC-IN-1

    CAS:
    <p>Tubulin/HDAC-IN-1 is a dual inhibitor for tubulin &amp; HDAC8, blocking polymerization &amp; targeting HDAC8 (IC50: 150 nM), and induces cancer cell apoptosis.</p>
    Fórmula:C21H18N4O3
    Forma y color:Solid
    Peso molecular:374.39
  • MBC-11

    CAS:
    <p>MBC-11: First bone-targeting bisphosphonate-etidronate conjugate with araC, may treat TIBD.</p>
    Fórmula:C11H20N3O14P3
    Pureza:>99.99% - >99.99%
    Forma y color:Solid
    Peso molecular:511.21
  • Sanazole

    CAS:
    <p>Sanazole is a 3-nitrotriazole cpd. It can affect the human cervical cancer cell line.</p>
    Fórmula:C7H11N5O4
    Forma y color:Solid
    Peso molecular:229.19
  • RET-IN-8

    CAS:
    <p>RET-IN-8 is an inhibitor of rearrangement kinase (RET) during transfection and can be used in cancer research.</p>
    Fórmula:C27H30N6O3
    Forma y color:Solid
    Peso molecular:486.57
  • EGFR-IN-59

    CAS:
    <p>EGFR-IN-59: EGFR inhibitor, IC50 = 190 nM, induces apoptosis, cytotoxic to A549 cells (IC50 = 8.62 μM) and WI38 cells (IC50 = 52.6 μM). Use: Various cancers.</p>
    Fórmula:C27H23N5O4S
    Forma y color:Solid
    Peso molecular:513.57
  • Antitumor agent-19

    CAS:
    <p>Antitumor agent-19 is a modulator of tumor-associated macrophages with EC50s of 17.18 μM and 18.87 μM in the RAW 264.7 cells and the BMDM cells.</p>
    Fórmula:C24H21ClF3N5O
    Pureza:98.95% - 99.38%
    Forma y color:Solid
    Peso molecular:487.9
  • RIP1 kinase inhibitor 6

    CAS:
    <p>RIP1 Kinase Inhibitor 6 is a potent and selective inhibitor of RIP1 kinase, demonstrating inhibitory activity with an IC50 of less than 100 nM in a human R1P1</p>
    Fórmula:C19H18F2N2O3
    Pureza:98%
    Forma y color:Solid
    Peso molecular:360.35
  • PhiKan 083 hydrochloride

    CAS:
    <p>PhiKan 083 HCl: carbazole, binds Y220C (Kd 167 μM), affinity in Ln229 (Kd 150 μM).</p>
    Fórmula:C16H19ClN2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:274.79
  • Atopaxar

    CAS:
    <p>Atopaxar (E5555), a reversible PAR-1 thrombin receptor antagonist, interferes with platelet signaling.</p>
    Fórmula:C29H38FN3O5
    Pureza:97.07% - 98.07%
    Forma y color:Solid
    Peso molecular:527.63
  • A-802715

    CAS:
    <p>A-802715 is a novel methylxanthine derivative that decreases the endogenous formation and blood levels of pro-inflammatory substances and increases the</p>
    Fórmula:C16H26N4O3
    Pureza:96.29%
    Forma y color:Solid
    Peso molecular:322.4
  • PHA-690509

    CAS:
    <p>PHA-690509 is a cyclin-dependent kinase 2 inhibitor. It potentially for the treatment of cancer.</p>
    Fórmula:C17H21N3O2S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:331.43
  • Dipin

    CAS:
    <p>Dipin is an Antineoplastic.</p>
    Fórmula:C12H24N6O2P2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:346.31
  • PDE5-IN-3

    CAS:
    <p>PDE5-IN-3: Inhibits PDE5 (1.57 nM), EGFR (5.827 μM), Wnt pathway (1286.96 ng/mL), induces apoptosis, and has antitumor effects.</p>
    Fórmula:C21H14BrN5O2
    Forma y color:Solid
    Peso molecular:448.27
  • Topoisomerase I inhibitor 2

    CAS:
    <p>ZML-8 selectively inhibits Top1, blocks G2/M phase, causes DNA damage, and induces apoptosis with anti-tumor properties.</p>
    Fórmula:C18H15NO3
    Forma y color:Solid
    Peso molecular:293.32
  • Prinomastat hydrochloride

    CAS:
    <p>Prinomastat HCl, an oral MMP (1, 3, 9) inhibitor, IC50s: 79, 6.3, 5.0 nM, shows antitumor activity.</p>
    Fórmula:C18H22ClN3O5S2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:459.97
  • PI3Kα-IN-6

    CAS:
    <p>PI3Kα-IN-6 (Compound 5b) is a PI3Kα inhibitor that exhibits anticancer effects without toxicity to normal cells.</p>
    Fórmula:C16H15IN2OS
    Forma y color:Solid
    Peso molecular:410.27
  • Epofolate

    CAS:
    <p>Epofolate: folate receptor-targeted antimitotic, delivers epothilone to cancer cells, inhibits mitosis, may halt tumor growth. Check clinical trials.</p>
    Fórmula:C67H92N16O22S3
    Forma y color:Solid
    Peso molecular:1569.74
  • ARP 101

    CAS:
    <p>ARP 101 is a selective matrix metalloproteinase-2 (MMP-2) inhibitor with anticancer activity.</p>
    Fórmula:C20H26N2O5S
    Pureza:98.26%
    Forma y color:Solid
    Peso molecular:406.5
  • SDZ 224-015

    CAS:
    SDZ 224-015 is an inhibitor of interleukin-1β (IL-1β) converting enzyme and caspase-1 with anti-COVID-19 and anti-inflammatory activity.
    Fórmula:C30H35Cl2N3O9
    Pureza:95.49% - 95.49%
    Forma y color:Solid
    Peso molecular:652.52
  • CDK1/Cyc B-IN-1

    CAS:
    <p>CDK1/Cyc B-IN-1: Potent CDK1/Cyc B inhibitor, IC50 97 nM, induces apoptosis, arrests G2/M cycle, halts cancer growth.</p>
    Fórmula:C14H12ClN3O2S2
    Forma y color:Solid
    Peso molecular:353.85
  • HJC0416

    CAS:
    <p>HJC0416 is a potent orally bioavailable signal transducer and activator of transcription 3 inhibitor.</p>
    Fórmula:C18H17ClN2O4S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:392.86
  • VU 0364739 hydrochloride

    CAS:
    VU 0364739 hydrochloride (VU 0364739 HCl) is a phospholipase D2 (PLD2) inhibitor that induces apoptosis and can be used in cancer research.
    Fórmula:C26H28ClFN4O2
    Pureza:99.36%
    Forma y color:Solid
    Peso molecular:482.98
  • VRT-043198

    CAS:
    <p>VRT-043198, a VX-765 metabolite, is a potent ICE/caspase-1 inhibitor, crossing the blood-brain barrier with K i of 0.8/0.6 nM.</p>
    Fórmula:C22H29ClN4O6
    Forma y color:Solid
    Peso molecular:480.94
  • cRIPGBM

    CAS:
    <p>cRIPGBM induces apoptosis in GBM CSCs by targeting RIPK2, with an EC50 of 68 nM in GBM-1 cells.</p>
    Fórmula:C26H20FN2O2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:411.45
  • DPBQ

    CAS:
    DPBQ (ZINC1620467) is a p53 activator.
    Fórmula:C24H14N2O2
    Pureza:98.08%
    Forma y color:Solid
    Peso molecular:362.38
  • RIPK1-IN-15

    CAS:
    <p>RIPK1-IN-15 (Compound 2.5) is a potent RIPK1 inhibitor that has the potential in neurodegenerative, autoimmune, and inflammatory diseases research [1].</p>
    Fórmula:C19H19N3O2
    Forma y color:Solid
    Peso molecular:321.37
  • Verrucarin J

    CAS:
    <p>Verrucarin J, a Myrothecium fungus metabolite, triggers apoptosis in some cancer cells and fights Candida, Mucor, and JUNV (IC50: 1.2 ng/mL).</p>
    Fórmula:C27H32O8
    Forma y color:Solid
    Peso molecular:484.54
  • PARP-1-IN-2

    CAS:
    <p>PARP-1-IN-2 is a potent PARP1 inhibitor that crosses the blood-brain barrier (IC50: 149 nM).PARP-1-IN-2 showed significant antiproliferative activity against</p>
    Fórmula:C22H15Cl2N3O2
    Pureza:98.82%
    Forma y color:Solid
    Peso molecular:424.28
  • PD180970

    CAS:
    <p>PD180970 is an inhibitor of Bcr-Abl with IC50s of 5 nM, 0.8 nM and 50 nM for the autophosphorylation of p210Bcr-Abl, Src and Kit.</p>
    Fórmula:C21H15Cl2FN4O
    Pureza:98.67%
    Forma y color:Solid
    Peso molecular:429.27
  • AP1867

    CAS:
    <p>AP1867 is a synthetic FKBP12F36V-directed ligand.</p>
    Fórmula:C38H47NO11
    Forma y color:Solid
    Peso molecular:693.78
  • LY5

    CAS:
    <p>LY5 is an inhibitor of STAT3 that acts by inhibiting cell viability, cell migration, and angiogenesis in medulloblastoma cells.</p>
    Fórmula:C15H11N3O4S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:329.33
  • PDGFR-IN-1

    CAS:
    <p>PDGFR-IN-1 is a platelet-derived growth factor receptor (PDGFR) inhibitor, strongly inhibiting PDGFRα and PDGFRβ, useful for studying solid tumors.</p>
    Fórmula:C25H30N8O
    Pureza:99.13% - 99.49%
    Forma y color:Solid
    Peso molecular:458.56
  • AFG206

    CAS:
    AFG206 is the novel first-generation type II" FLT3 inhibitor."
    Fórmula:C20H19N3O2
    Forma y color:Solid
    Peso molecular:333.38
  • Mcl1-IN-4

    CAS:
    Mcl1-IN-4 is an inhibitor of Mcl1 ( IC50:0.2 μM).
    Fórmula:C28H26N2O5S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:502.58
  • Didesmethylrocaglamide

    CAS:
    <p>Didesmethylrocaglamide, a Rocaglamide derivative, is a potent eukaryotic initiation factor 4A (eIF4A) inhibitor that exhibits strong growth-inhibitory effects,</p>
    Fórmula:C27H27NO7
    Forma y color:Solid
    Peso molecular:477.51
  • Semapimod

    CAS:
    <p>Semapimod is an inhibitor of proinflammatory cytokine production, capable of suppressing TNF-α, IL-1β, and IL-6.</p>
    Fórmula:C34H52N18O2
    Forma y color:Solid
    Peso molecular:744.9
  • DC-CPin711

    CAS:
    <p>DC-CPin711: Potent, selective CBP bromodomain inhibitor, IC50=0.0626 μM; arrests G1 cell cycle, induces apoptosis.</p>
    Fórmula:C23H22N4O2
    Forma y color:Solid
    Peso molecular:386.45
  • PI3K/AKT-IN-2

    CAS:
    <p>PI3K/AKT-IN-2 inhibits PI3K/AKT, EMT, induces apoptosis, and blocks tubulin polymerization.</p>
    Fórmula:C32H27BrO10
    Forma y color:Solid
    Peso molecular:651.45
  • PDK4-IN-1

    CAS:
    <p>PDK4-IN-1 is an anthraquinone derivative and a potent and orally active inhibitor of pyruvate dehydrogenase kinase 4 (PDK4)(IC50 value of 84 nM).</p>
    Fórmula:C22H19N3O2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:357.41
  • MMPSI

    CAS:
    <p>MMPSI (Caspase-3/7 Inhibitor I) is a caspase 3 and caspase 7 inhibitor that inhibits ischemic injury in cardiomyocytes and can be used to study cardioprotection</p>
    Fórmula:C14H16N2O5S
    Pureza:99.74%
    Forma y color:Solid
    Peso molecular:324.35
  • BN201

    CAS:
    <p>BN201 (OCS-05) is a neuroprotective drug by activating SGK2 and FOXO3 pathway. BN201 is able to regulate multiple kinases in the IGF1 pathway and cross BBB.</p>
    Fórmula:C25H38FN5O4
    Pureza:99.42% - 99.42%
    Forma y color:Solid
    Peso molecular:491.6
  • W1131

    CAS:
    <p>W1131 is a potent STAT3 inhibitor and ferroptosis trigger, reducing cancer progression and 5-FU resistance.</p>
    Fórmula:C23H19N5O4
    Forma y color:Solid
    Peso molecular:429.43
  • Docetaxel trihydrate

    CAS:
    <p>Docetaxel trihydrate (RP-56976 Trihydrate) is an antineoplastic agent that has a unique mechanism of action as an inhibitor of cellular mitosis.</p>
    Fórmula:C43H59NO17
    Pureza:98.68% - >99.99%
    Forma y color:White Crystalline Powder
    Peso molecular:861.95
  • N1,N11-Diethylnorspermine

    CAS:
    <p>DENSPM: potent anticancer, spurs polyamine breakdown, triggers cytochrome c release and caspase 3, kills GBM via SSAT &amp; H2O2.</p>
    Fórmula:C13H32N4
    Forma y color:Solid
    Peso molecular:244.42
  • DNL343

    CAS:
    <p>DNL343 is an eIF2B activator that inhibits stress granule (SG) assembly induced by the C9ORF72 dipeptide repeat.</p>
    Fórmula:C20H19ClF3N3O4
    Pureza:99.96%
    Forma y color:Solid
    Peso molecular:457.83
  • BR102375

    CAS:
    <p>BR102375 is a non-TZD PPAR γ full agonist (EC50: 0.28 μM) for the treatment of type 2 diabetes.</p>
    Fórmula:C31H34N6O4
    Pureza:98%
    Forma y color:Solid
    Peso molecular:554.64
  • Antitumor agent-44

    CAS:
    <p>Antitumor agent-44 (Compound 5n) elicits potent antitumor effects by inducing disruption of mitochondrial homeostasis, cell cycle arrest, and apoptosis in human</p>
    Fórmula:C24H15N3O3
    Forma y color:Solid
    Peso molecular:393.39
  • RET-IN-12

    CAS:
    <p>RET-IN-12 is a RET inhibitor capable of acting on RET(WT) (IC50: 0.3 nM) and RET(V804M) (IC50: 1 nM).</p>
    Fórmula:C30H30F3N5O4
    Forma y color:Solid
    Peso molecular:581.59
  • Tezacitabine

    CAS:
    <p>Tezacitabine, a nucleoside analogue, inhibits ribonucleotide reductase, disrupts DNA replication, and induces apoptosis in tumor cells.</p>
    Fórmula:C10H12FN3O4
    Forma y color:Solid
    Peso molecular:257.22
  • RLX

    CAS:
    RLX (PD 139530) is a PI3K/Akt/FoxO3a signal inhibitor with anticancer,antitussive and anti-asthmatic activity,colon cancer,toxicity toward A549 cells..
    Fórmula:C13H14N2O
    Pureza:99.81%
    Forma y color:Solid
    Peso molecular:214.26
  • Infliximab

    CAS:
    <p>Infliximab is a chimeric monoclonal antibody that inhibits TNF-α. Infliximab can be used to treat Crohn's disease and rheumatoid arthritis. Cost-effective and quality-assured.</p>
    Pureza:98% - 99.70%
    Forma y color:Liquid
    Peso molecular:149 kDa
  • Topoisomerase II inhibitor 3

    CAS:
    <p>Acridone-based Topoisomerase II inhibitor 3 targets topo IIα/β (IC50: 0.17μM α, 0.23μM β), causes DNA damage, and induces apoptosis.</p>
    Fórmula:C18H20N4O4
    Forma y color:Solid
    Peso molecular:356.38
  • CEP-40125

    CAS:
    <p>CEP-40125 (RXDX-107) is a DNA alkylating agent for the study of advanced solid tumors.</p>
    Fórmula:C28H45Cl2N3O2
    Pureza:98.28%
    Forma y color:Solid
    Peso molecular:526.58
  • Methylisothiazolinone

    CAS:
    <p>Methylisothiazolinone (MI) is a powerful synthetic biocide and preservative within the group of isothiazolinones.</p>
    Fórmula:C4H5NOS
    Pureza:99.78%
    Forma y color:Colorless Prisms Liquid
    Peso molecular:115.15
  • CMLD010509

    CAS:
    <p>CMLD010509 (SDS-1-021) inhibits oncogenic proteins MDM2, CCND1, MYC, MAF, MCL-1 in multiple myeloma.</p>
    Fórmula:C27H26BrNO7
    Pureza:98%
    Forma y color:Solid
    Peso molecular:556.4
  • Topoisomerase I inhibitor 5

    CAS:
    <p>Topoisomerase I inhibitor 5 halts DNA replication, induces MCF-7 cell apoptosis, and overcomes drug resistance. IC50 value is noted.</p>
    Fórmula:C24H24N2O2
    Forma y color:Solid
    Peso molecular:372.46
  • Polyphyllin II

    CAS:
    <p>Polyphyllin II (Chonglou Saponin II) has hemostasis, expectorant, bacteriostasis, anticytotoxic, anti-pregnancy kill sperm effects.</p>
    Fórmula:C44H70O16
    Pureza:99.92%
    Forma y color:Solid
    Peso molecular:855.02
  • Misetionamide

    CAS:
    <p>Misetionamide: Oral oxathiazin-like, GAPDH inhibitor with anticancer properties for research use.</p>
    Fórmula:C3H7NO3S
    Forma y color:Solid
    Peso molecular:137.16
  • VU0285655-1

    CAS:
    <p>VU0285655-1, a PLD2 inhibitor, halts PLD2-deficient cell growth and protects against high glucose-induced cell death. Used in diabetic retinopathy research.</p>
    Fórmula:C25H27N5O2
    Pureza:99.73%
    Forma y color:Solid
    Peso molecular:429.51
  • HDAC8-IN-3

    CAS:
    <p>HDAC8-IN-3 (P19) inhibits HDAC8 (IC50 9.3 μM), induces leukemic cell apoptosis, and enhances thermal stability.</p>
    Fórmula:C18H12N4O3S2
    Forma y color:Solid
    Peso molecular:396.44
  • S130

    CAS:
    S130 is a high affinity, selectiveATG4B (a major cysteine protease) inhibitor (IC50 of 3.24 μM).It suppresses autophagy flux.
    Fórmula:C24H25N3O2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:387.47
  • CTX1

    CAS:
    <p>CTX1 is a small molecule activator of p53.</p>
    Fórmula:C14H10N4
    Pureza:98%
    Forma y color:Solid
    Peso molecular:234.26
  • SD-36

    CAS:
    SD-36: Potent, selective PROTAC STAT3 degrader, Kd ~50 nM, effective on mutants, IC50=10 nM, strong anti-tumor effects, enables mouse tumor regression.
    Fórmula:C59H62F2N9O12P
    Pureza:98% - >99.99%
    Forma y color:Soild
    Peso molecular:1158.15
  • STAT5-IN-2

    CAS:
    <p>STAT5-IN-2 is an inhibitor of STAT5 with antileukemic effects (EC50s: 9 μM and 5 μM in K562 and KU812 cells, respectively).</p>
    Fórmula:C26H27N3O
    Pureza:99.55%
    Forma y color:Solid
    Peso molecular:397.51
  • Erasin


    <p>Erasin is a STAT3 inhibitor induces apoptosis in various cancer cell lines (e.g., MDA-MB-231, HCC-827) and against Erlotinib-resistant cancer cells.</p>
    Fórmula:C20H19N3O3
    Forma y color:Solid
    Peso molecular:349.38
  • Sparfosic acid trisodium

    CAS:
    Sparfosic acid trisodium is a CAD (carbamoyl-phosphate synthetase 2) inhibitor and also an aspartate transcarbamoyl transferase inhibitor with antitumour
    Fórmula:C6H9NNaO8P
    Pureza:98%
    Forma y color:Solid
    Peso molecular:277.1
  • Declopramide

    CAS:
    Declopramide (OXI-104) is a chemosensitizer with antitumor activity that can be used to study colorectal cancer and inflammatory bowel disease.
    Fórmula:C13H20ClN3O
    Pureza:98.53%
    Forma y color:Solid
    Peso molecular:269.77
  • AZD-5991 Racemate

    CAS:
    <p>AZD-5991 Racemate is the racemate of AZD-5991. (Rac)-AZD-5991 is a novel Mcl-1 inhibitor induces upregulation of BCL2,BCL-XL, CMYC and MCL1 in AML cell lines.</p>
    Fórmula:C35H34ClN5O3S2
    Forma y color:Solid
    Peso molecular:672.26
  • Mcl1-IN-11

    CAS:
    <p>Mcl1-IN-11 (Compound G) is a selective Mcl-1 inhibitor, less potent at Bcl-2, with Kis of 0.06 and 4.2 μM, respectively.</p>
    Fórmula:C38H41N3O5S2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:683.88
  • NSC260594

    CAS:
    <p>NSC260594 is a chemical compound that promotes apoptosis by binding to the shallow groove of the Mcl-1 protein and suppressing its expression through down-</p>
    Fórmula:C29H24N6O3
    Forma y color:Solid
    Peso molecular:504.54
  • MSN-125

    CAS:
    <p>MSN-125 inhibits Bax/Bak apoptosis, protects neurons, prevents MOMP with IC50 of 4μM.</p>
    Fórmula:C36H38BrN3O6
    Pureza:98%
    Forma y color:Solid
    Peso molecular:688.61
  • AK301

    CAS:
    <p>AK301 is a potent and selective inhibitor of tubulin polymerization and an effective sensitizer of cancer cells to apoptotic ligands (EC50 &lt; 200 nM).</p>
    Fórmula:C19H21ClN2O2
    Pureza:99.27%
    Forma y color:Solid
    Peso molecular:344.84
  • ROC-325

    CAS:
    <p>ROC-325: orally active autophagy inhibitor with anticancer effects, induces kidney cancer cell death; selective action.</p>
    Fórmula:C28H27ClN4OS
    Pureza:99.26%
    Forma y color:Solid
    Peso molecular:503.06
  • ADU-S100

    CAS:
    <p>ADU-S100 (MIW815) is a STING agonist that significantly induces the production of IFN-β,TNF-α,IL-6,and MCP-1,induces TBK1 and IRF3 phosphorylation,antitumour.</p>
    Fórmula:C20H24N10O10P2S2
    Pureza:99.83%
    Forma y color:Solid
    Peso molecular:690.54
  • LOM612

    CAS:
    LOM612 is a potent and specific FOXO relocator FOXO3a reporter protein endogenous FOXO3a and FOXO1 , down-regulates c-Myc and cyclin D1, anti-proliferative.
    Fórmula:C13H10N2O2S
    Forma y color:Solid
    Peso molecular:258.3
  • Bax activator-1

    CAS:
    <p>Bax activator-1 (compound 106) is a Bax activator. It induces Bax-dependent tumor cell apoptosis[1].</p>
    Fórmula:C29H36N4O3
    Forma y color:Solid
    Peso molecular:488.62
  • (5Z,2E)-CU-3

    CAS:
    <p>(5Z,2E)-CU-3 is a potent and selective inhibitor of DGKα isozyme with an IC50 value of 0.6 μM and inhibition of DGKα by competing ATP with a Km value of 0.48 mM</p>
    Fórmula:C16H12N2O4S3
    Pureza:99.02%
    Forma y color:Solid
    Peso molecular:392.47
  • Sparfosic Acid

    CAS:
    <p>Sparfosic Acid (Acide sparfosique) is an aspartate carbamoyltransferase inhibitor with antitumor activity and can be used to study advanced renal cell carcinoma</p>
    Fórmula:C6H10NO8P
    Pureza:98.89%
    Forma y color:Solid
    Peso molecular:255.12
  • ICG-001

    CAS:
    <p>ICG001 is a β-catenin/TCF-mediated transcription inhibitor that selectively blocks β-catenin/CBP interaction.Cost-effective and quality-assured.</p>
    Fórmula:C33H32N4O4
    Pureza:99.55% - 99.62%
    Forma y color:Solid
    Peso molecular:548.63
  • Jolkinolide B

    CAS:
    <p>Jolkinolide B is a bioactive diterpene isolated from the roots of Euphorbia fischeriana Steud.</p>
    Fórmula:C20H26O4
    Pureza:99.39% - 99.7%
    Forma y color:Solid
    Peso molecular:330.42
  • MI-389

    CAS:
    MI-389 is a PROTAC degrader that induces the degradation of receptor tyrosine kinases (RTKs), useful for leukemia research.
    Fórmula:C35H35FN6O6
    Pureza:98.12%
    Forma y color:Solid
    Peso molecular:654.69
  • TJ08

    CAS:
    <p>TJ08 has anticancer properties and can effectively induce G1/S phase blockade while promoting apoptosis in a variety of cancer cells.</p>
    Fórmula:C22H16FN3O4
    Pureza:99.89%
    Forma y color:Solid
    Peso molecular:405.38
  • EP12

    CAS:
    <p>EP12, a c-Myc inhibitor and G4 stabilizer, induces apoptosis and DNA damage in multiple myeloma cells while obstructing P65/P50 nuclear translocation by</p>
    Fórmula:C26H22FN3O2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:427.47
  • Telomerase-IN-4

    CAS:
    <p>Telomerase-IN-4 is a potent inhibitor of telomerase with antiproliferative properties and induces apoptosis [1].</p>
    Fórmula:C21H18N4OS2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:406.52
  • Anticancer agent 147

    CAS:
    <p>Compound 6j (Anticancer agent 147), a sophoridine derivative and ferroptosis inducer, promotes intracellular accumulation of Fe2+, reactive oxygen species (ROS</p>
    Fórmula:C32H40BrN3O2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:578.58
  • Bisindolylmaleimide VIII

    CAS:
    <p>Bisindolylmaleimide VIII (Ro-31-7549) is a selective and highly potent protein kinase C (PKC) inhibitor.</p>
    Fórmula:C24H22N4O2
    Pureza:97% - 98.01%
    Forma y color:Solid
    Peso molecular:398.46
  • Antiproliferative agent-32

    CAS:
    <p>Antiproliferative agent-32 (Compound 1c) impedes phosphorylation within the PI3K/Akt/mTOR signaling pathway, restrains proliferation of Huh7 and SK-Hep-1 cells</p>
    Fórmula:C19H15NO2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:289.33
  • Telomerase-IN-5

    CAS:
    <p>Telomerase-IN-5 is a potent inhibitor of telomerase with antiproliferative properties, and it induces apoptosis [1].</p>
    Fórmula:C22H20N4OS2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:420.55
  • (R)-STU104

    CAS:
    (R)-STU104 is a TAK1-MKK3 protein-protein interaction (PPI) inhibitor. (R)-STU104 is a candidate compound for the treatment of ulcerative colitis.
    Fórmula:C18H18O4
    Pureza:98.91% - 99.42%
    Forma y color:Solid
    Peso molecular:298.33
  • L6H21

    CAS:
    <p>L6H21 is an MD-2 inhibitor that can be used to study cognitive impairment and brain damage.</p>
    Fórmula:C18H18O4
    Pureza:99.26%
    Forma y color:Solid
    Peso molecular:298.33
  • ZINC69391

    CAS:
    <p>ZINC69391 inhibits Rac1, reduces cancer cell growth and metastasis, and induces apoptosis.</p>
    Fórmula:C14H14F3N5
    Pureza:99.61%
    Forma y color:Solid
    Peso molecular:309.29
  • SAR125844

    CAS:
    <p>SAR125844, a potent and highly selective inhibitor of the MET receptor tyrosine kinase (RTK), for intravenous administration. (IC50 value of 4.2 nmol/L)</p>
    Fórmula:C25H23FN8O2S2
    Pureza:98.73%
    Forma y color:Solid
    Peso molecular:550.63
  • CCCI-01

    CAS:
    <p>CCCI-01: Centrosome cluster inhibitor with anticancer properties, induces apoptosis, aids in non-cross-resistant drug research.</p>
    Fórmula:C11H9N3O4
    Pureza:>99.99%
    Forma y color:Solid
    Peso molecular:247.21
  • IST5-002

    CAS:
    <p>IST5-002: Potent Stat5a/b blocker, IC50 1.5μM/3.5μM, targets prostate cancer &amp; CML.</p>
    Fórmula:C17H20N5O7P
    Pureza:99.36%
    Forma y color:Solid
    Peso molecular:437.34
  • Benpyrine

    CAS:
    Benpyrine, an oral TNF-α inhibitor (KD 82.1 μM, IC50 0.109 μM), may help in inflammatory/autoimmune studies.
    Fórmula:C16H16N6O
    Forma y color:Solid
    Peso molecular:308.34
  • YLT-11


    <p>YLT-11: Oral PLK4 inhibitor, Kd 5.2 nM; less effective on PLK1/2/3; inhibits cancer cell growth and induces G2/M arrest and apoptosis.</p>
    Fórmula:C24H24N6O
    Forma y color:Solid
    Peso molecular:412.49
  • Caspase-3/7 activator 3


    <p>Caspase-3/7 activator 3 triggers apoptosis with tumor selectivity and anti-proliferative effects.</p>
    Fórmula:C24H27NO5
    Forma y color:Solid
    Peso molecular:409.47
  • Anticancer agent 63

    CAS:
    <p>Compound 3h fights various cancers; most effective on MCF-7 (IC50 3.4 μM). Triggers apoptosis; alters Bcl-2, IL-2, Caspase-3 levels, has antioxidant effects.</p>
    Fórmula:C17H24F3NOSe
    Forma y color:Solid
    Peso molecular:394.33
  • Cyclamidomycin

    CAS:
    <p>Cyclamidomycin is an antibiotic. It also functions as an inhibitor of nucleoside diphosphokinase of Escherichia coli.</p>
    Fórmula:C7H10N2O
    Forma y color:Solid
    Peso molecular:138.17
  • GKK1032B

    CAS:
    <p>GKK1032B: antiproliferative, antibacterial, halts HeLa S3, MCF-7, Vero cells, B. subtilis, M. tuberculosis.</p>
    Fórmula:C32H39NO4
    Forma y color:Solid
    Peso molecular:501.66
  • VS 8

    CAS:
    <p>VS 8: potent oral VEGFR-2 inhibitor, anti-angiogenic, induces cancer cell apoptosis &amp; migration, acts on CSCs.</p>
    Fórmula:C26H20F3N3O3
    Forma y color:Solid
    Peso molecular:479.45
  • VEGFR-2-IN-28

    CAS:
    <p>VEGFR-2-IN-28 is a potent inhibitor of VEGFR-2 (IC50: 0.83 μM). VEGFR-2-IN-28 induces apoptosis and exhibits antitumor effects.</p>
    Fórmula:C26H17N7O7
    Forma y color:Solid
    Peso molecular:539.46
  • Tubulin polymerization-IN-13

    CAS:
    <p>Compound 4f inhibits tubulin polymerization (IC50: 0.37 μM), induces apoptosis, and has notable anti-cancer properties.</p>
    Fórmula:C20H21NO6
    Forma y color:Solid
    Peso molecular:371.38
  • PSB 0474

    CAS:
    <p>P2Y6 receptor agonist</p>
    Fórmula:C17H20N2O13P2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:522.29
  • MMP-9-IN-5

    CAS:
    <p>MMP-9-IN-5: MMP-9 and AKT inhibitor (IC50: 4.49 nM and 1.34 nM), induces apoptosis for cancer research.</p>
    Fórmula:C27H20IN3O4
    Forma y color:Solid
    Peso molecular:577.37
  • RET-IN-20


    <p>RET-IN-20: potent RET inhibitor (IC50 = 13.7 nM), reduces p-Ret/p-Shc, induces apoptosis, anti-tumor effects.</p>
    Fórmula:C32H33FN6O4
    Forma y color:Solid
    Peso molecular:584.64
  • CDK9-IN-18

    CAS:
    <p>CDK9-IN-18: Potent CDK9 blocker, anticancer, induces apoptosis, low cellular activity.</p>
    Fórmula:C27H20N8O
    Forma y color:Solid
    Peso molecular:472.5
  • 5HPP-33

    CAS:
    5HPP-33 is an microtubule-stabilizer with the properties of antiproliferative and antimitotic.
    Fórmula:C20H21NO3
    Forma y color:Solid
    Peso molecular:323.39
  • VEGFR-2/BRAF-IN-2


    <p>VEGFR-2/BRAF-IN-2 inhibits VEGFR-2, BRAF V600E, BRAF WT (IC50: 0.111/0.089/0.071 µM); induces G1 arrest and apoptosis.</p>
    Fórmula:C26H21ClF3N5O3S2
    Forma y color:Solid
    Peso molecular:608.05
  • HDAC6-IN-4

    CAS:
    <p>HDAC6-IN-4 (C10), an oral, selective, potent HDAC6 inhibitor with low toxicity, IC50: 23 nM, promotes apoptosis and strong anti-tumor action.</p>
    Fórmula:C30H38N2O5
    Forma y color:Solid
    Peso molecular:506.63
  • p-DDAP

    CAS:
    <p>p-DDAP inhibits cell invasion and reduces MMP-9 activity and expression.</p>
    Fórmula:C18H31NO
    Pureza:98%
    Forma y color:Solid
    Peso molecular:277.44
  • GW-3333

    CAS:
    <p>GW-3333 inhibits matrix metalloproteinases and TNF-Converting Enzyme, showing potential as an antiarthritic therapy.</p>
    Fórmula:C22H36N4O4
    Pureza:98%
    Forma y color:Solid
    Peso molecular:420.55
  • BRD0476

    CAS:
    <p>BRD0476 prevents pancreatic β-cell death by blocking IFN-γ-induced JAK2 &amp; STAT1 without inhibiting JAK kinase activity.</p>
    Fórmula:C35H38N4O8S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:674.76
  • Anti-osteoporosis agent-1

    CAS:
    <p>Anti-osteoporosis agent-1 (comp 4aa) is an effective RPA (replication protein A) inhibitor, demonstrating potency with an IC50 value of 18 μM [1].</p>
    Fórmula:C20H19ClN2O2
    Forma y color:Solid
    Peso molecular:354.83
  • Ramentaceone

    CAS:
    <p>Ramentaceone is an antineoplastic.</p>
    Fórmula:C11H8O3
    Pureza:98%
    Forma y color:Solid
    Peso molecular:188.18
  • Anticancer agent 47

    CAS:
    <p>Compound 4j: potent anticancer agent; halts cell growth, induces apoptosis and G0/G1 arrest; significant in vivo tumor reduction.</p>
    Fórmula:C19H14N2O4S
    Forma y color:Solid
    Peso molecular:366.39
  • Antiproliferative agent-19


    Antiproliferative agent-19 induces apoptosis and G2/M cell cycle arrest in lung cancer cells.
    Fórmula:C26H23NO
    Forma y color:Solid
    Peso molecular:365.47
  • (1S,2S)-Bortezomib

    CAS:
    <p>(1S,2S)-Bortezomib (Bortezomib) is an enantiomer of Bortezomib.</p>
    Fórmula:C19H25BN4O4
    Pureza:99.6%
    Forma y color:Solid
    Peso molecular:384.24
  • TPB15

    CAS:
    <p>TPB15, an oral Hh inhibitor, blocks Smo activity, arrests cell cycle, induces apoptosis, and shows potent antitumor effects with low toxicity.</p>
    Fórmula:C18H9Cl4N5O
    Forma y color:Solid
    Peso molecular:453.11
  • (Z)-4EGI-1

    CAS:
    <p>(Z)-4EGI-1, a Z-isomer, inhibits eIF4E/eIF4G; binds eIF4E (IC50=43.5 μM, Kd=8.74 μM); anticancer properties.</p>
    Fórmula:C18H12Cl2N4O4S
    Forma y color:Solid
    Peso molecular:451.28
  • Bcl-2/Mcl-1-IN-1

    CAS:
    <p>Bcl-2/Mcl-1-IN-1 is an inhibitor of Bcl-2 (Ki: 4.53 μM) and Mcl-1 (Ki: 1.19 μM).Bcl-2/Mcl-1-IN-1 can be used in cancer research.</p>
    Fórmula:C28H23NO3
    Forma y color:Solid
    Peso molecular:421.49
  • EGFR/HER2/TS-IN-1

    CAS:
    <p>EGFR/HER2/TS-IN-1 inhibits EGFR (0.203 μM), HER2 (0.088 μM), TS (0.168 μM), and induces apoptosis in MCF7 cells.</p>
    Fórmula:C24H15N5O4S2
    Forma y color:Solid
    Peso molecular:501.54