Apoptosis
Los inhibidores de la apoptosis son compuestos que previenen o retrasan el proceso de muerte celular programada, conocido como apoptosis. Estos inhibidores son vitales para estudiar los mecanismos de supervivencia celular y se utilizan para investigar enfermedades donde la apoptosis está desregulada, como el cáncer, los trastornos neurodegenerativos y las enfermedades autoinmunes. Al modular la apoptosis, estos inhibidores pueden ayudar en el desarrollo de terapias dirigidas a controlar la muerte celular. En CymitQuimica, ofrecemos una amplia selección de inhibidores de la apoptosis de alta calidad para apoyar su investigación en biología celular, oncología y campos relacionados.
Subcategorías de "Apoptosis"
- ASK(9 productos)
- BCL(8 productos)
- Caspasa(144 productos)
- FOXO1(3 productos)
- IAP(67 productos)
- Mdm2(12 productos)
- PD-1 / PD-L1(139 productos)
- PDK(9 productos)
- PERK(26 productos)
- Serina / treonina quinasa(18 productos)
- Survivin(14 productos)
- TNF(93 productos)
- c-RET(61 productos)
- p53(63 productos)
Mostrar 6 subcategorías más
Se han encontrado 6084 productos de "Apoptosis"
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5HPP-33
CAS:5HPP-33 is an microtubule-stabilizer with the properties of antiproliferative and antimitotic.Fórmula:C20H21NO3Forma y color:SolidPeso molecular:323.39BLM-IN-1
CAS:BLM-IN-1: BLM inhibitor, KD 1.81 μM, IC50 0.95 μM; causes DNA damage, apoptosis, stops cancer cell growth.Fórmula:C28H35FN4OForma y color:SolidPeso molecular:462.6Anti-osteoporosis agent-1
CAS:Anti-osteoporosis agent-1 (comp 4aa) is an effective RPA (replication protein A) inhibitor, demonstrating potency with an IC50 value of 18 μM [1].Fórmula:C20H19ClN2O2Forma y color:SolidPeso molecular:354.83Ramentaceone
CAS:Ramentaceone is an antineoplastic.Fórmula:C11H8O3Pureza:98%Forma y color:SolidPeso molecular:188.18MIR96-IN-1
CAS:MIR96-IN-1 selectively inhibits biogenesis of microRNA-96, upregulating a protein target (FOXO1) and inducing apoptosis in cancer cells.Fórmula:C33H48N8O2Forma y color:SolidPeso molecular:588.79Apoptosis inducer 6
CAS:Apoptosis inducer 6 is an anticancer agent with broad-spectrum anticancer activity that induces apoptosis, which triggers cell death.Fórmula:C27H26N4O3SForma y color:SolidPeso molecular:486.59B-Raf IN 9
CAS:B-Raf IN 9 is a potent B-Raf inhibitor (IC50=24.79 nM), induces G2/M arrest and apoptosis, and inhibits PC-3 prostate cancer cells (IC50=7.83 μM).Fórmula:C23H20N4OSForma y color:SolidPeso molecular:400.5PI3Kα-IN-7
CAS:<p>PI3Kα-IN-7 (Compound A12) is a potent PI3Kα inhibitor, and also inhibits PI3Kβ.</p>Fórmula:C17H22N8O2SForma y color:SolidPeso molecular:402.47PERK-IN-3
CAS:PERK-IN-3 is a potent inhibitor of PERK(IC50 of 7.4 nM).Fórmula:C22H16F2N4O2Pureza:98%Forma y color:SolidPeso molecular:406.38Antitumor agent-83
Antitumor agent-83 activates BAX protein, impedes tumor growth, triggers apoptosis, and is stable in vitro.Fórmula:C29H30N6O2Forma y color:SolidPeso molecular:494.59MDM2-IN-1
CAS:MDM2-IN-1 is a synthetic MDM2-p53 interaction (MDM2) inhibitor and contains the trans (D-)configuration.Fórmula:C23H21Cl2FN2O3Forma y color:SolidPeso molecular:463.33Prinomastat hydrochloride
CAS:<p>Prinomastat HCl, an oral MMP (1, 3, 9) inhibitor, IC50s: 79, 6.3, 5.0 nM, shows antitumor activity.</p>Fórmula:C18H22ClN3O5S2Pureza:98%Forma y color:SolidPeso molecular:459.97VEGFR-2/BRAF-IN-1
VEGFR-2/BRAF-IN-1 inhibits VEGFR-2, BRAF V600E & BRAF WT with IC50 of 49, 63 and 5 nM, triggers apoptosis, and halts G1/S cell cycle.Fórmula:C26H20Cl2F3N5O3S2Forma y color:SolidPeso molecular:642.5Apoptotic agent-1
CAS:Compound 8a is an apoptotic agent that boosts Fas receptor and Cyto C genes to fight cancer with low toxicity.Fórmula:C12H6ClN5O2SForma y color:SolidPeso molecular:319.73Anticancer agent 164
CAS:CML-IN-1, also known as compound 7 and compound 4, is a potent anticancer agent that demonstrates a strong induced-apoptosis effect in the human chronic myeloidFórmula:C21H23F3N8O2S2Pureza:98%Forma y color:SolidPeso molecular:540.58Ac-IETD-CHO
CAS:Ac-IETD-CHO is a potent, reversible inhibitor of granzyme B and caspase 8, which also impedes Fas-mediated apoptosis, hemorrhagic conditions, and liver failure.Fórmula:C21H34N4O10Pureza:98%Forma y color:SolidPeso molecular:502.52CMLD012072
CAS:CMLD012072 is a potent eukaryotic initiation factor 4A (eIF4A) inhibitor with potent anti-neoplastic activity. It can induce RNA clamping of eIF4A1 and eIF4A2.Fórmula:C32H32N2O7Pureza:98%Forma y color:SolidPeso molecular:556.61(R)-STU104
CAS:(R)-STU104 is a TAK1-MKK3 protein-protein interaction (PPI) inhibitor. (R)-STU104 is a candidate compound for the treatment of ulcerative colitis.Fórmula:C18H18O4Pureza:98.91% - 99.42%Forma y color:SolidPeso molecular:298.33LG190178
CAS:<p>LG190178, a vitamin D receptor (VDR) ligand, is a therapeutic agent used for the treatment of psoriasis, osteoporosis, and secondary hyperparathyroidism.</p>Fórmula:C28H42O5Forma y color:SolidPeso molecular:458.63STAT3-IN-3
CAS:STAT3-IN-3 is a potent and selective signal transducer inhibitor and transcription 3 (STAT3) activator.Fórmula:C27H26BrN3O6SPureza:98%Forma y color:SolidPeso molecular:600.48RIP1 kinase inhibitor 7
CAS:RIP1 Kinase Inhibitor 7 (Compound 41) serves as a potent inhibitory agent for receptor interacting protein 1 kinase (RIP1) with an IC50 of under 100 nM.Fórmula:C20H20FN3OPureza:98%Forma y color:SolidPeso molecular:337.39RS6212
CAS:<p>RS6212 is a specific lactate dehydrogenase (LDH) inhibitor (IC50=12.03 μ M）。 RS6212 shows strong anticancer activity in a variety of cancer cell lines.</p>Fórmula:C20H22N4O3SForma y color:SolidPeso molecular:398.48Sibiriline
CAS:Sibiriline is a Receptor-Interacting Protein Kinase 1 inhibitor that acts by preventing immune-dependent hepatitis.Fórmula:C13H10N2OPureza:98%Forma y color:SolidPeso molecular:210.23AG6033
CAS:AG6033, a novel CRBN modulator, degrades GSPT1/IKZF1 and inhibits various tumors.Fórmula:C30H23N5O4Forma y color:SolidPeso molecular:517.53CK2/ERK8-IN-1
CAS:TMCB inhibits CK2 (Ki: 0.25 µM), ERK8 (IC50: 0.50 µM), PIM1, DYRK1A, HIPK2 (Ki: 8.65-15.25 µM), and induces apoptosis.Fórmula:C11H9Br4N3O2Pureza:98.22%Forma y color:SolidPeso molecular:534.82SMBA1
CAS:SMBA1 is a Bax agonist with antitumor activity that can induce cell cycle arrest and apoptosis in malignant glioma cells.Fórmula:C20H13NO3Pureza:99.2%Forma y color:SolidPeso molecular:315.32HDAC-IN-31
CAS:HDAC-IN-31: Oral HDAC inhibitor; targets HDAC1, 2, 3; weak on HDAC8; potential in fighting lymphoma.Fórmula:C25H24N4O2Forma y color:SolidPeso molecular:412.48PARP-1-IN-2
CAS:<p>PARP-1-IN-2 is a potent PARP1 inhibitor that crosses the blood-brain barrier (IC50: 149 nM).PARP-1-IN-2 showed significant antiproliferative activity against</p>Fórmula:C22H15Cl2N3O2Pureza:98.82%Forma y color:SolidPeso molecular:424.28GLUT4-IN-2
CAS:GLUT4-IN-2, selective GLUT4 blocker; IC50: 6.8μM (GLUT4), 11.4μM (GLUT1). Induces apoptosis, G0/G1 arrest, has antitumor effects.Fórmula:C17H11N3O4S2Pureza:99.90%Forma y color:SolidPeso molecular:385.42Tubulin polymerization-IN-31
CAS:Compound 4c, inhibits tubulin polymerization, IC50 3.64 μM, and induces cancer cell apoptosis.Fórmula:C18H13ClFN3Forma y color:SolidPeso molecular:325.77CHMFL-ABL/KIT-155
CAS:CHMFL-ABL/KIT-155 is a highly potent and orally active type II ABL/c-KIT dual kinase inhibitor (IC50s: 46 nM/75 nM).Fórmula:C33H38F3N5O3Pureza:98%Forma y color:SolidPeso molecular:609.68CRA-026440
CAS:CRA-026440(PCI-34051) is a highly potent HDAC inhibitor with inhibitory effects on HDAC1, HDAC2, HDAC3, HDAC6, HDAC8 and HDAC10 with Ki values of 4,14,11,15,7Fórmula:C23H24N4O4Pureza:96.42%Forma y color:SolidPeso molecular:420.46Didesmethylrocaglamide
CAS:Didesmethylrocaglamide, a Rocaglamide derivative, is a potent eukaryotic initiation factor 4A (eIF4A) inhibitor that exhibits strong growth-inhibitory effects,Fórmula:C27H27NO7Forma y color:SolidPeso molecular:477.51LLL3
CAS:LLL3 is a small molecule STAT3 inhibitor.Fórmula:C16H10O4Forma y color:SolidPeso molecular:266.25NMK-TD-100
CAS:NMK-TD-100: Microtubule disruptor, anti-proliferative, blocks mitosis, causes apoptosis in HeLa; IC50=17.5µM for tubulin polymerization.Fórmula:C19H17N3O3SPureza:98%Forma y color:SolidPeso molecular:367.42CEP-40125
CAS:CEP-40125 (RXDX-107) is a DNA alkylating agent for the study of advanced solid tumors.Fórmula:C28H45Cl2N3O2Pureza:98.28%Forma y color:SolidPeso molecular:526.58CMLD010509
CAS:CMLD010509 (SDS-1-021) inhibits oncogenic proteins MDM2, CCND1, MYC, MAF, MCL-1 in multiple myeloma.Fórmula:C27H26BrNO7Pureza:98%Forma y color:SolidPeso molecular:556.4Topoisomerase I inhibitor 5
CAS:Topoisomerase I inhibitor 5 halts DNA replication, induces MCF-7 cell apoptosis, and overcomes drug resistance. IC50 value is noted.Fórmula:C24H24N2O2Forma y color:SolidPeso molecular:372.46NSC260594
CAS:NSC260594 is a chemical compound that promotes apoptosis by binding to the shallow groove of the Mcl-1 protein and suppressing its expression through down-Fórmula:C29H24N6O3Forma y color:SolidPeso molecular:504.54AK301
CAS:AK301 is a potent and selective inhibitor of tubulin polymerization and an effective sensitizer of cancer cells to apoptotic ligands (EC50 < 200 nM).Fórmula:C19H21ClN2O2Pureza:99.75%Forma y color:SolidPeso molecular:344.84Flupenthixol
CAS:Flupentixol is a typical antipsychotic drug of the thioxanthene class. Flupentixol is also used in low doses as an antidepressant.Fórmula:C23H25F3N2OSPureza:98%Forma y color:SolidPeso molecular:434.52HDAC-IN-39
CAS:HDAC-IN-39 inhibits HDAC1-3 (IC50: 1.07-2.27 μM), arrests G2/M phase, hinders microtubule polymerization, and is effective against drug-resistant cancers.Fórmula:C27H26N4O4SForma y color:SolidPeso molecular:502.58OT-82
CAS:OT-82 is a NAMPT inhibitor with anticancer activity and cytotoxicity and is used in the study of leukemias.Fórmula:C26H21FN4OPureza:98.91% - 99.315%Forma y color:SolidPeso molecular:424.47Ref: TM-T12330
2mg144,00€5mg235,00€10mg376,00€25mg747,00€50mg1.169,00€100mg1.549,00€1mL*10mM (DMSO)259,00€eIF4A3-IN-2
CAS:eIF4A3-IN-2 is a highly selective and noncompetitive eukaryotic initiation factor 4A-3 inhibitor with an IC50 of 110 nM.Fórmula:C25H19Br2ClN4O2Pureza:98%Forma y color:SolidPeso molecular:602.71D-Cl-amidine
CAS:D-Cl-amidine is an effective and highly selective PAD1 inhibitor. D-Cl-amidine has a good correlation and no obvious toxicity.Fórmula:C14H19ClN4O2Pureza:98%Forma y color:SolidPeso molecular:310.78DRAK2-IN-1
CAS:Drak2-in-1: ATP-competitive DRAK2 inhibitor; IC50 = 3 nM, KI = 0.26 nM; affects DRAK1 (IC50 = 51 nM).Fórmula:C21H20N4O3Forma y color:SolidPeso molecular:376.41LSD1-IN-14
CAS:LSD1-IN-14: potent LSD1 inhibitor, IC50 0.89 μM; hinders A549/THP-1 cell growth, induces tumor cell apoptosis.Fórmula:C21H24FN5Forma y color:SolidPeso molecular:365.45Nafamostat hydrochloride
CAS:Nafamostat hydrochloride is a synthetic serine protease inhibitor and is an anticoagulant.Fórmula:C19H19Cl2N5O2Pureza:98%Forma y color:SolidPeso molecular:420.29NSC745885
CAS:NSC745885 decreases EZH2, has selective cancer cell toxicity, and is studied for bladder and OSCC.Fórmula:C14H6N2O2SPureza:98%Forma y color:SolidPeso molecular:266.27bpV(phen)
CAS:bpV(phen) is a potent protein tyrosine phosphatase (PTP) and PTEN inhibitor (IC50s: 343 nM, 920 nM, and 38 nM for PTP-β, PTP-1B, and PTEN).Fórmula:C12H8KN2O5VPureza:98%Forma y color:SolidPeso molecular:350.24
