Apoptosis
Los inhibidores de la apoptosis son compuestos que previenen o retrasan el proceso de muerte celular programada, conocido como apoptosis. Estos inhibidores son vitales para estudiar los mecanismos de supervivencia celular y se utilizan para investigar enfermedades donde la apoptosis está desregulada, como el cáncer, los trastornos neurodegenerativos y las enfermedades autoinmunes. Al modular la apoptosis, estos inhibidores pueden ayudar en el desarrollo de terapias dirigidas a controlar la muerte celular. En CymitQuimica, ofrecemos una amplia selección de inhibidores de la apoptosis de alta calidad para apoyar su investigación en biología celular, oncología y campos relacionados.
Subcategorías de "Apoptosis"
- ASK(9 productos)
- BCL(11 productos)
- Caspasa(144 productos)
- FOXO1(3 productos)
- IAP(67 productos)
- Mdm2(12 productos)
- PD-1 / PD-L1(139 productos)
- PDK(9 productos)
- PERK(26 productos)
- Serina / treonina quinasa(18 productos)
- Survivin(14 productos)
- TNF(93 productos)
- c-RET(62 productos)
- p53(63 productos)
Mostrar 6 subcategorías más
Se han encontrado 6070 productos de "Apoptosis"
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L 741742 (free base)
CAS:L 741742 is an effective and highly selective antagonist of the D4 dopamine receptor (Ki: 1700, 770, and 3.5 nM at cloned human D2, D3, and D4 receptors).Fórmula:C23H25ClN2OPureza:98%Forma y color:SolidPeso molecular:380.91ALC67
CAS:ALC67, a novel 3-propionyl thiazolidine-4-carboxylic acid ethyl ester, activates caspase-9, showing potent anticancer properties.Fórmula:C15H15NO3SPureza:98%Forma y color:SolidPeso molecular:289.35NSC-741909
CAS:NSC-741909 is an anticancer agent that acts by suppressing the growth of several cell lines.Fórmula:C16H14ClNOPureza:98%Forma y color:SolidPeso molecular:271.74ATB-337
CAS:S-Diclofenac, an NSAID with H2S-releasing moiety, protects gastric mucosa while inhibiting prostaglandins.Fórmula:C23H15Cl2NO2S3Forma y color:SolidPeso molecular:504.47KF24345
CAS:KF24345 is an inhibitor of adenosine uptake.Fórmula:C31H38N6O5Forma y color:SolidPeso molecular:574.67CPI-7c
CAS:CPI-7c inhibits MDM2-p53 interaction and promotes MDM2 degradation.Fórmula:C22H18N2O3Pureza:98%Forma y color:SolidPeso molecular:358.39NU-8165
CAS:NU-8165 is an MDM2-p53 protein-protein interaction inhibitor.Fórmula:C24H22ClNO3Pureza:98%Forma y color:SolidPeso molecular:407.89Dabuzalgron HCl
CAS:Dabuzalgron, an adrenoceptor agonist, is used potentially for the treatment of urinary incontinence.Fórmula:C12H17Cl2N3O3SPureza:98%Forma y color:SolidPeso molecular:354.25Gea 3162
CAS:GEA 3162 blocks ADP-induced platelet clumping in PRP and boosts cGMP in granulocytes and leukocytes.Fórmula:C7H4Cl2N4OPureza:98%Forma y color:SolidPeso molecular:231.04MEB55
CAS:MEB55, an anticancer agent, acts by disrupting DNA repair and halting growth in prostate, colon, lung and breast cancer cells.Fórmula:C22H17NO4SPureza:98%Forma y color:SolidPeso molecular:391.44D44
CAS:D44 is a Plasmodium FKBPs inhibitor.Fórmula:C16H16N4OSForma y color:SolidPeso molecular:312.39GSK962
CAS:GSK962 is a GSK963 inactive enantiomer. It can be used to confirm the on-target effects.Fórmula:C14H18N2OPureza:99.75%Forma y color:SolidPeso molecular:230.31NHI-2
CAS:NHI-2 is an LDHA inhibitor (IC50 14.7 µM) that blocks glycolysis, induces apoptosis and cell cycle arrest, and suppresses tumor growth in melanoma models.Fórmula:C17H12F3NO3Pureza:99.981%Forma y color:SolidPeso molecular:335.28MG-262
CAS:MG-262 is a reversible proteasome inhibitor with multiple biological activities [1] [2] [3].Fórmula:C25H42BN3O6Forma y color:SolidPeso molecular:491.43M199
CAS:M199, a novel inhibitor of TLR3/9 activation, induces secretion of IL-6, IL-8 and TNFalpha in human PBMCs.Fórmula:C17H17N3OPureza:98%Forma y color:SolidPeso molecular:279.34Mitochonic Acid 35
CAS:Mitochonic Acid 35 is a dual TNF-α and TGF-β1 inhibitor that acts by inhibiting IκB kinase phosphorylation and Smad3 phosphorylation.Fórmula:C19H19NO5Pureza:98%Forma y color:SolidPeso molecular:341.36DC-5163
CAS:DC-5163 inhibits GAPDH (IC50: 176.3 nM, Kd: 3.192 μM), targets cancer cell growth and glycolysis.Fórmula:C18H20ClN3OSPureza:98%Forma y color:SolidPeso molecular:361.89NSC-639829
CAS:NSC-639829 is an anti-tumor compound that requires a solubilizing agent for dissolution.Fórmula:C21H20BrN5O3Pureza:99.53% - 99.77%Forma y color:SolidPeso molecular:470.32AZM475271
CAS:AZM475271 is a potent and selective inhibitor of Src kinase(IC50 : 5 nM)Fórmula:C23H27ClN4O3Pureza:99.78%Forma y color:SolidPeso molecular:442.94Rooperol
CAS:Rooperol: a norlignan with p38α inhibiting, immunomodulatory, antitumor, antibacterial, anticonvulsant, and antioxidant properties.Fórmula:C17H14O4Pureza:98%Forma y color:SolidPeso molecular:282.29Antitumor agent-19
CAS:Antitumor agent-19 is a modulator of tumor-associated macrophages with EC50s of 17.18 μM and 18.87 μM in the RAW 264.7 cells and the BMDM cells.Fórmula:C24H21ClF3N5OPureza:98.95% - 99.38%Forma y color:SolidPeso molecular:487.9Ref: TM-T10341
1mg115,00€2mg172,00€5mg255,00€10mg374,00€25mg562,00€50mg787,00€100mg1.074,00€500mg2.147,00€1mL*10mM (DMSO)305,00€CN128 hydrochloride
CAS:<p>CN128 hydrochloride is an oral, selective hydroxypyridone iron chelator for β-thalassemia research.</p>Fórmula:C15H18ClNO3Forma y color:SolidPeso molecular:295.76PIK-C98
CAS:PIK-C98 is an inhibitor of PI3K that acts by displaying potent preclinical activity against multiple myeloma.Fórmula:C16H10Cl2N2OSPureza:98%Forma y color:SolidPeso molecular:349.23ORY-1001 free base
CAS:ORY-1001: potent KDM1A inhibitor (IC50 <20nM), selective, affects THP-1 cell gene regulation and apoptosis, hinders MV(4;11) cell growth (EC50 <1nM).Fórmula:C15H22N2Pureza:98%Forma y color:SolidPeso molecular:230.35Tigilanol tiglate
CAS:Tigilanol tiglate (EBC-46) is a PKC/C1 domain activator. Tigilanol tiglate induces immunogenic cell death and tumour regression.Fórmula:C30H42O10Pureza:98%Forma y color:SolidPeso molecular:562.652'-Deoxyadenosine
CAS:2'-Deoxyadenosine (NSC-141848) is the DNA nucleoside A. It pairs with deoxythymidine (T) in double-stranded DNA.Fórmula:C10H13N5O3Pureza:99.71%Forma y color:SolidPeso molecular:251.24MM-102
CAS:MM-102 (HMTase Inhibitor IX) is a potent inhibitor of WDR5/MLL interaction with IC50 of 2.4 nM and Ki of less than 1 nM in a WDR5 binding assay.Cost-effective and quality-assured.Fórmula:C35H49F2N7O4Pureza:98.77% - 99.99%Forma y color:SolidPeso molecular:669.8Ref: TM-T6333
1mg39,00€2mg51,00€5mg105,00€10mg168,00€25mg351,00€50mg543,00€100mg777,00€1mL*10mM (DMSO)156,00€Selicrelumab
CAS:Selicrelumab (RG-7876) is an antibody targeting CD40 with potential anti-tumor activity for the study of pancreatic cancer.Pureza:98.7% (SDS-PAGE); 95.2% (SEC-HPLC) - 98.7% (SDS-PAGE); 95.2% (SEC-HPLC)Forma y color:LiquidCHS-828 nicotinate
CAS:CHS-828, or GMX-1778, is a potent NAMPT inhibitor with anticancer properties, active against tumors and enhanced by certain drugs.Fórmula:C25H27ClN6O3Forma y color:SolidPeso molecular:494.97Mepazine acetate
CAS:Mepazine acetate is a MALT1 inhibitor.Fórmula:C21H26N2O2SForma y color:SolidPeso molecular:370.51Antitumor agent-81
CAS:Antitumor agent-81, a P62-RNF168 agonist, reduces H2A ubiquitination, hinders DNA repair, and inhibits tumor growth.Fórmula:C19H19N7O3Forma y color:SolidPeso molecular:393.42-chloro Palmitic Acid
CAS:2-chloro Palmitic acid triggers NETosis, elevates COX-2, adhesion molecules in HCAECs, and induces apoptosis and caspase-3 in THP-1 cells/monocytes.Fórmula:C16H31ClO2Forma y color:SolidPeso molecular:290.87Anticancer agent 31
CAS:Anticancer agent 31, a 1,3-diphenylurea quinoxaline derivative, halts S phase and triggers apoptosis.Fórmula:C28H21F2N5O2Forma y color:SolidPeso molecular:497.5ABN401
CAS:ABN401: potent c-MET inhibitor (IC50: 10 nM), cytotoxic to MET-dependent cancers, blocks tumor c-MET phosphorylation, for cancer research.Fórmula:C29H34N12OForma y color:SolidPeso molecular:566.66Cl-Necrostatin-1
CAS:Cl-Necrostatin-1 is an inhibitor of receptor-interacting protein kinase. It inhibits RIPK1 activity.Fórmula:C13H12ClN3OSForma y color:SolidPeso molecular:293.77RSH-7
CAS:RSH-7 is a potent dual inhibitor of BTK and FLT3, with IC50s of 47 and 12 nM, respectively.RSH-7 has antiproliferative and antitumor activities, inducingFórmula:C22H25FN8OPureza:99.43%Forma y color:SolidPeso molecular:436.49CAY10406
CAS:CAY10406, a trifluoromethyl isatin sulfonamide, selectively targets and inhibits caspase-3 and -7, key in apoptosis, with no data on its inhibition potency.Fórmula:C27H23F3N2O5SForma y color:SolidPeso molecular:544.54MDH1-IN-2
CAS:MDH1-IN-2 is a potent MDH1 inhibitor with potential anticancer activity for the study of diseases related to the immune system.Fórmula:C25H33NO5Pureza:99.21%Forma y color:SolidPeso molecular:427.5315(S)-HpETE
CAS:15(S)-HpETE is a product of arachidonic acid formed in the 15-lipoxygenase pathway and inhibits angiogenesis.Fórmula:C20H32O4Forma y color:SolidPeso molecular:336.47XMD15-44
CAS:XMD15-44, a RET kinase inhibitor, demonstrates potent growth-inhibitory effects on RAT1 cells transformed by RET/C634R and RET/M918T, with IC50 values of 11.5 nM and 8.3 nM, respectively. It effectively inhibits RET kinase activity and signaling in human thyroid cancer cell lines harboring oncogenic RET alleles, thereby reducing cell proliferation.Fórmula:C29H29F3N4OPeso molecular:506.56Ferroptosis-IN-4
CAS:Ferroptosis-IN-4 (compound 6k), an inhibitor of ferroptosis, exhibits an EC50 of 20 μM and lacks significant cytotoxicity. It demonstrates a protective role in glycerol-induced RM-AKI mice by alleviating kidney dysfunction [1].Fórmula:C17H24ClN3O2Peso molecular:337.84PBOX-15
CAS:PBOX-15 induces apoptosis, regulates death receptors, enhances TRAIL effects, and inhibits T cell migration in myeloma cells.Fórmula:C28H19NO3Forma y color:SolidPeso molecular:417.46APX2009
CAS:APX2009, a 2nd-gen APE1/Ref-1 inhibitor, curbs NFkB activity, survivin, and prostate cancer cell growth; induces cell cycle arrest.Fórmula:C21H25NO4Forma y color:SolidPeso molecular:355.43Ceranib-2
CAS:<p>Ceranib-2, a ceramidase inhibitor (IC50: 28 μM, SKOV3), reduces sphingosine/S1P and promotes apoptosis, showing anticancer properties.</p>Fórmula:C25H19NO3Pureza:98.49%Forma y color:SolidPeso molecular:381.42KU-0058948
CAS:KU-0058948: PARP inhibitor, triggers cell cycle arrest and apoptosis in myeloid leukemia cells in vitro.Fórmula:C21H21FN4O2Forma y color:SolidPeso molecular:380.42TJ08
CAS:TJ08 has anticancer properties and can effectively induce G1/S phase blockade while promoting apoptosis in a variety of cancer cells.Fórmula:C22H16FN3O4Pureza:99.89%Forma y color:SolidPeso molecular:405.38EP12
CAS:EP12, a c-Myc inhibitor and G4 stabilizer, induces apoptosis and DNA damage in multiple myeloma cells while obstructing P65/P50 nuclear translocation byFórmula:C26H22FN3O2Pureza:98%Forma y color:SolidPeso molecular:427.47Telomerase-IN-4
CAS:Telomerase-IN-4 is a potent inhibitor of telomerase with antiproliferative properties and induces apoptosis [1].Fórmula:C21H18N4OS2Pureza:98%Forma y color:SolidPeso molecular:406.52Ac-IETD-CHO
CAS:Ac-IETD-CHO is a potent, reversible inhibitor of granzyme B and caspase 8, which also impedes Fas-mediated apoptosis, hemorrhagic conditions, and liver failure.Fórmula:C21H34N4O10Pureza:98%Forma y color:SolidPeso molecular:502.52
