Apoptosis
Los inhibidores de la apoptosis son compuestos que previenen o retrasan el proceso de muerte celular programada, conocido como apoptosis. Estos inhibidores son vitales para estudiar los mecanismos de supervivencia celular y se utilizan para investigar enfermedades donde la apoptosis está desregulada, como el cáncer, los trastornos neurodegenerativos y las enfermedades autoinmunes. Al modular la apoptosis, estos inhibidores pueden ayudar en el desarrollo de terapias dirigidas a controlar la muerte celular. En CymitQuimica, ofrecemos una amplia selección de inhibidores de la apoptosis de alta calidad para apoyar su investigación en biología celular, oncología y campos relacionados.
Subcategorías de "Apoptosis"
- ASK(9 productos)
- BCL(11 productos)
- Caspasa(143 productos)
- FOXO1(3 productos)
- IAP(67 productos)
- Mdm2(12 productos)
- PD-1 / PD-L1(139 productos)
- PDK(9 productos)
- PERK(25 productos)
- Serina / treonina quinasa(18 productos)
- Survivin(14 productos)
- TNF(89 productos)
- c-RET(58 productos)
- p53(63 productos)
Mostrar 6 subcategorías más
Se han encontrado 5966 productos de "Apoptosis"
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MJN68390
CAS:<p>MJN68390 has an apparent IC50 value of 15 μM against CASP8 and shows no activity against CASP10.</p>Fórmula:C24H28ClN3O3Pureza:98.86%Forma y color:SolidPeso molecular:441.95GSK-3β inhibitor 3
CAS:GSK-3β inhibitor 3 is a covalent inhibitor (IC50: 6.6 μM) of glycogen synthase kinase 3β (GSK-3β) that is potent, selective, and irreversible.GSK-3β inhibitor 3Fórmula:C18H14FNO2SPureza:97.53%Forma y color:SolidPeso molecular:327.37TNIK-IN-3
CAS:<p>TNIK-IN-3 is a highly potent and orally active inhibitor of Traf2- and Nck-interacting protein kinase (TNIK).</p>Fórmula:C23H18FN3O2Pureza:98.39%Forma y color:SolidPeso molecular:387.41GSK854
CAS:GSK854 is a selective TNNI3K inhibitor reducing heart damage and stress post-infarction in mice.Fórmula:C18H19ClN6O4S2Pureza:98.91%Forma y color:SolidPeso molecular:482.96Mepazine
CAS:Mepazine, a MALT1 inhibitor, blocks GSTMALT1 (IC50: 0.83μM) and GSTMALT1 325-760 (IC50: 0.42μM), promoting apoptosis and reducing cell viability.Fórmula:C19H22N2SPureza:99.88% - 99.92%Forma y color:SolidPeso molecular:310.46Benitrobenrazide
CAS:Benitrobenrazide (Hexokinase 2 inhibitor 1) is a novel orally available hexokinase 2 (HK2) inhibitor with anticancer and antitumor activity for cancer research.Fórmula:C14H11N3O6Pureza:96.87%Forma y color:SolidPeso molecular:317.25MK-28
CAS:MK-28 is a PERK agonist that reduces toxicity in a Huntington's disease model.MK-28 has a significant killing effect on MK28 gastric cancer cells.Fórmula:C24H20N4O2Forma y color:SolidPeso molecular:396.44(S)-Enitociclib
CAS:(S)-Enitociclib (VIP152) is a selective CDK9 inhibitor that inhibits the transcription of anti-apoptotic and pro-survival proteins.Fórmula:C19H18F2N4O2SPureza:98.98%Forma y color:SolidPeso molecular:404.43Bomedemstat ditosylate
CAS:<p>Bomedemstat (IMG-7289) is an LSD1 inhibitor for acute myeloid leukemia, MDS, and Myelofibrosis; induces apoptosis by regulating p53, PUMA, and BCLXL.</p>Fórmula:C42H50FN7O8S2Pureza:99.05%Forma y color:SolidPeso molecular:864.02Trk-IN-9
CAS:<p>Trk-IN-9 is a TRK inhibitor with anticancer and antiproliferative activity and can be used in cancer research.</p>Fórmula:C23H24ClFN6OPureza:98.15%Forma y color:SolidPeso molecular:454.93RS1-PDK1 inhibitor
CAS:<p>RS1-PDK1 inhibitor (RS 1) is a selective inhibitor of the protein kinase PDK1 that can be used to treat and prevent disease or disorders.</p>Fórmula:C15H9ClN2O2S3Pureza:98.12%Forma y color:SolidPeso molecular:380.89R306465
CAS:R306465 (JNJ-16241199) is an HDAC 1 inhibitor with broad-spectrum anti-tumor activity, inducing apoptosis, and can be used to study solid tumors.Fórmula:C19H19N5O4SPureza:98.46% - 99.54%Forma y color:SolidPeso molecular:413.45BCL6-IN-7
CAS:BCL6-IN-7 (BCL6 inhibitor-7) is a BCL6 corepressor-interaction inhibitor with potential antitumor activity, used in lymphoma research.Fórmula:C18H15ClN6OPureza:99.03%Forma y color:SolidPeso molecular:366.8Deferitazole
CAS:Deferitazole (FBS 0701) is a novel and orally active, selective and high affinity iron chelator.Fórmula:C18H25NO7SPureza:99.48%Forma y color:SolidPeso molecular:399.46PARP/PI3K-IN-1
CAS:PARP/PI3K-IN-1 is a PARP and PI3K dual inhibitor with anticancer and antiproliferative activities for the study of breast, pancreatic and lung cancers.Fórmula:C33H28F4N8O3Pureza:99.59%Forma y color:SolidPeso molecular:660.62Atrosab
CAS:Atrosab is a humanized IgG1 antibody targeting TNFR1, inhibiting TNF-mediated apoptosis, and can be used to study inflammatory and neurodegenerative diseases.Pureza:95.22% (SEC-HPLC) - >95.0% (SDS-PAGE); 95.68% (SEC-HPLC)Forma y color:LiquidPeso molecular:146.12 kDaRo 90-7501
CAS:Ro 90-7501, an amyloid β42 (Aβ42) protofibril and TPR-dependent PP5 inhibitor, is a novel cervical cancer cell radiosensitizer that inhibits HCMV.Fórmula:C20H16N6Pureza:97.21% - 99.72%Forma y color:SolidPeso molecular:340.38Apostatin-1
CAS:Apostatin-1 (Apt-1) is a novel TRADD inhibitor. Apostatin-1 can bind to a pocket on the N-terminal TRAF2 binding domain of TRADD.Fórmula:C19H27N3OSPureza:99.31%Forma y color:SolidPeso molecular:345.5Antifolate C2
CAS:Antifolate C2 (AGF 154) inhibits tumor growth with 0.14 nM IC, useful in cancer/autoimmune research.Fórmula:C19H21N5O6SPureza:99.57%Forma y color:SolidPeso molecular:447.46UNC0321
CAS:UNC0321 is an effective inhibitor of histone methyltransferase G9a with a Ki of 63 pM and with IC50s 9 nM and 6 nM in ECSD and CLOT assays.Fórmula:C27H45N7O3Pureza:99.80%Forma y color:SolidPeso molecular:515.69Vamotinib
CAS:Vamotinib (PF-114) is a tyrosine kinase inhibitor with antiproliferative and antitumor activity.Vamotinib is used in the study of Alzheimer's disease.Fórmula:C29H27F3N6OPureza:99.64%Forma y color:SolidPeso molecular:532.56LQZ-7F
CAS:LQZ-7F is a survivin dimerization inhibitor with anticancer activity.LQZ-7F induces proteasome-dependent survivin degradation and inhibits human tumor growth.Fórmula:C14H7N9O3Pureza:98.64%Forma y color:SolidPeso molecular:349.26C6 Ceramide
CAS:<p>C6 Ceramide (N-hexanoylsphingosine) is an activator of the ceramide pathway that arrests cells in the G0/G1 phase by activating ERK.</p>Fórmula:C24H47NO3Pureza:99.67%Forma y color:SolidPeso molecular:397.63RET-IN-23
CAS:<p>RET-IN-23 is an orally available and highly potent RET inhibitor with significant antitumor activity for the study of non-small cell lung cancer.</p>Fórmula:C28H28FN11Pureza:97.46%Forma y color:SolidPeso molecular:537.59AOH1160
CAS:AOH1160 is an inhibitor of proliferating cell nuclear antigen (PCNA).Fórmula:C25H20N2O3Pureza:98.46% - 99.52%Forma y color:SolidPeso molecular:396.44HS38
CAS:HS38: DAPK-specific ATP-competitive inhibitor; Kds: DAPK1 (300 nM), PIM3 (200 nM), ZIPK (280 nM); useful in smooth muscle disorder research.Fórmula:C14H12ClN5O2SPureza:98.19%Forma y color:SolidPeso molecular:349.8MMRi64
CAS:<p>MMRi64 inhibits Mdm2-MdmX, boosts p53, triggers apoptosis, and is used in cancer research.</p>Fórmula:C22H17Cl2N3OPureza:99.93%Forma y color:SolidPeso molecular:410.3Alethine
CAS:Alethine is a small antitumor compound used to treat cancers and infections, boosting T-cell cytotoxicity by raising TNFα.Fórmula:C10H22N4O2S2Pureza:99.78%Forma y color:SolidPeso molecular:294.44BCP-T.A
CAS:<p>BCP-T.A is an iron death inducer that acts by binding to GPX4.</p>Fórmula:C23H19Cl2N3OSPureza:99.49%Forma y color:SolidPeso molecular:456.39CTA 056
CAS:CTA 056 is an ITK inhibitor that inhibits the growth of MOLT-4 xenograft tumors in mice and can be used to study autoimmune disorders.Fórmula:C35H34N6OPureza:97.22% - 97.76%Forma y color:SolidPeso molecular:554.68Necrostatin-5
CAS:Necrostatin-5 (Nec-5) inhibits RIP1 kinase, prevents cell necrosis, and protects Fadd-deficient Jurkat cells with an EC50 of 240 nM.Fórmula:C19H17N3O2S2Pureza:98.03%Forma y color:SolidPeso molecular:383.49p53-MDM2-IN-1
CAS:<p>p53-MDM2-IN-1 (Example 30), an inhibitor targeting the p53-MDM2/X protein interaction, exhibits a K i value of 23.35 µM.</p>Fórmula:C23H20ClN3O3Pureza:99.98%Forma y color:SoildPeso molecular:421.88FA16
FA16 is a selective, metabolically stable ferroptosis inducer with an IC50 value of 1.26 μM.FA16 is a derivative of 2-(trifluoromethyl)benzimidazole.FA16Fórmula:C22H27F3N4O2SPureza:99.44%Forma y color:SolidPeso molecular:468.54Erastin2
CAS:<p>Erastin2 is an iron death inducer that induces cell death by binding to the lipophilic free radical trapping antioxidant ferrostatin-1 or the iron chelator DFO.</p>Fórmula:C36H35ClN4O4Pureza:99.63%Forma y color:SolidPeso molecular:623.14Anticancer agent 110
CAS:Anticancer Agent 110 exhibits potent in vitro anti-leukemia activity, demonstrating high cytotoxicity against K-562 lineage chronic myelogenous leukemia cellsFórmula:C18H13FN6OSPureza:98%Forma y color:SolidPeso molecular:380.4ZDLD20
CAS:ZDLD20 is a CDK4 inhibitor with anti-HCT116 and anticancer activity that inhibits colony formation and blocks the G1 phase of the cell cycle.Fórmula:C22H22N6OPureza:98.59%Forma y color:SolidPeso molecular:386.45XX-650-23
CAS:<p>XX-650-23 is a CREB inhibitor that induces apoptosis and cell cycle arrest in AML cells and can be used to study acute myeloid leukemia (AML).</p>Fórmula:C18H12N2O2Pureza:97.01%Forma y color:SolidPeso molecular:288.3cRIPGBM chloride
CAS:cRIPGBM chloride is a pro-apoptotic derivative found in GBM cancer stem cells with anti-tumor activity, inducing caspase-1-dependent apoptosis.Fórmula:C26H20ClFN2O2Pureza:99.75%Forma y color:SolidPeso molecular:446.9CCT020312
CAS:<p>CCT020312 (0-9 µM, 24 h) treatment of medium HT29 cells for 24 h resulted in a concentration-dependent loss of P-S608-pRB.Cost-effective and quality-assured.</p>Fórmula:C31H30Br2N4O2Pureza:98.63%Forma y color:SolidPeso molecular:650.4UCB-5307
CAS:UCB-5307 inhibits TNFR1, binds TNFα with 9 nM KD, shows slow kinetics (KD=6 nM), and penetrates hTNF/hTNFR1 complexes.Fórmula:C22H21N3OPureza:98.76%Forma y color:SolidPeso molecular:343.42CUDC-427
CAS:<p>CUDC-427 (GDC-0917) is an orally bioactive and pan antagonist of inhibitor of apoptosis proteins(IAPs). CUDC-427 can be used in research on cancers.</p>Fórmula:C29H36N6O4SPureza:99.92%Forma y color:SolidPeso molecular:564.7LCS3
CAS:<p>LCS3 is a reversible and non-competitive synergistic inhibitor of glutathione disulfide reductase (GSR) and thioredoxin reductase 1 (TXNRD1) with IC50s of 3.3</p>Fórmula:C11H7ClN2O4Pureza:99.68%Forma y color:SolidPeso molecular:266.64AQ4
CAS:AQ4 is a topoisomerase II inhibitor and DNA-inserting agent that inhibits proliferation and induces apoptosis in two cell lines.Fórmula:C22H28N4O4Pureza:96.28% - 97.15%Forma y color:SolidPeso molecular:412.48Imipramine
CAS:Imipramine (Dimipressin) is a Fascin1 inhibitor with antitumor activity and induces apoptosis.Fórmula:C19H24N2Pureza:99.4%Forma y color:White To Off-White /Hydrochloride/ SolidPeso molecular:280.41AMG PERK 44
CAS:AMG PERK 44 is a PERK inhibitor that induces autophagy.AMG PERK 44 inhibits GCN2 and B-Raf and can be used in cancer research.Fórmula:C34H29ClN4O2Pureza:98.8% - 99.81%Forma y color:SolidPeso molecular:561.07Epristeride
CAS:Epristeride (ONO-9302) is a steroidal 5-alpha-reductase isoform 2 inhibitor that inhibits SR isoform 2. Epristeride reduces prostate size.Fórmula:C25H37NO3Pureza:98.12% - >99.99%Forma y color:SolidPeso molecular:399.57P505-15 Acetate
CAS:<p>P505-15 Acetate inhibits spleen tyrosine kinase, reduces immune response and inflammation, and lowers arthritis severity.</p>Fórmula:C21H27N9O3Pureza:99.99%Forma y color:SolidPeso molecular:453.5RIPK3-IN-1
CAS:RIPK3-IN-1 is a RIPK3 inhibitor (IC50: 9.1 nM) that inhibits c-Met kinase, RIPK1, and RIPK2 activity and can be used to study apoptosis.Fórmula:C29H25FN4O4Pureza:98.27%Forma y color:SolidPeso molecular:512.53STAT3-IN-13
CAS:STAT3-IN-13 is a STAT3 inhibitor with antiproliferative activity that induces apoptosis and can be used to study breast and liver cancer.Fórmula:C21H20N6O3SPureza:98.89%Forma y color:SolidPeso molecular:436.49Tiomolibdate diammonium
CAS:<p>Tiomolibdate diammonium (NSC-286644) blocks SOD1 and COX, acting as an antiangiogenic and antitumor agent.</p>Fórmula:H8MoN2S4Pureza:98%Forma y color:Brown To Black Iridescent Crystalline PowderPeso molecular:260.28
