Apoptosis
Los inhibidores de la apoptosis son compuestos que previenen o retrasan el proceso de muerte celular programada, conocido como apoptosis. Estos inhibidores son vitales para estudiar los mecanismos de supervivencia celular y se utilizan para investigar enfermedades donde la apoptosis está desregulada, como el cáncer, los trastornos neurodegenerativos y las enfermedades autoinmunes. Al modular la apoptosis, estos inhibidores pueden ayudar en el desarrollo de terapias dirigidas a controlar la muerte celular. En CymitQuimica, ofrecemos una amplia selección de inhibidores de la apoptosis de alta calidad para apoyar su investigación en biología celular, oncología y campos relacionados.
Subcategorías de "Apoptosis"
- ASK(6 productos)
- BCL(11 productos)
- Caspasa(127 productos)
- FOXO1(3 productos)
- IAP(65 productos)
- Mdm2(12 productos)
- PD-1 / PD-L1(126 productos)
- PDK(9 productos)
- PERK(24 productos)
- Serina / treonina quinasa(15 productos)
- Survivin(13 productos)
- TNF(91 productos)
- c-RET(51 productos)
- p53(62 productos)
Mostrar 6 subcategorías más
Se han encontrado 5622 productos de "Apoptosis"
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Lenalidomide hemihydrate
CAS:<p>Lenalidomide hemihydrate inhibits TNF-α (IC50=13nM) and binds CRBN/DDB1 complexes.</p>Fórmula:C13H13N3O3H2OPureza:96.22%Forma y color:SolidPeso molecular:268.28ASTX660
CAS:<p>Tolinapant (ASTX660) is an orally bioavailable cIAP1/2 and XIAP antagonist.Cost-effective and quality-assured.</p>Fórmula:C30H42FN5O3Pureza:98.33% - 99.85%Forma y color:SolidPeso molecular:539.68Palomid 529
CAS:<p>Palomid 529 (SG 00529) has been used in trials studying the treatment of Age-Related Macular Degeneration.</p>Fórmula:C24H22O6Pureza:98.40% - 98.59%Forma y color:SolidPeso molecular:406.43BI-6C9
CAS:<p>BI-6C9 is an inhibitor of tBid (Kd = 20 μM).BI-6c9 prevented MOMP and mitochondrial fission, and protected the cells from cell death.</p>Fórmula:C23H25N3O4S2Pureza:98.39%Forma y color:SolidPeso molecular:471.59Alogliptin
CAS:<p>Alogliptin (SYR-322)(SYR-322) is a potent, selective inhibitor of DPP-4 with IC50 of <10 nM, exhibits greater than 10, 000-fold selectivity over DPP-8 and DPP-9</p>Fórmula:C18H21N5O2Pureza:99.63%Forma y color:SolidPeso molecular:339.39Takinib
CAS:<p>Takinib (EDHS-206) is a specific and effective TAK1 inhibitor(IC50= 9.5 nM).</p>Fórmula:C18H18N4O2Pureza:98.29% - 99.35%Forma y color:SolidPeso molecular:322.36ML-210
CAS:<p>ML-210 (CID 49766530) is a glutathione peroxidase 4 (GPX4) inhibitor. ML-210 has antitumor activity and induces ferroptosis. Cost-effective and quality-assured.</p>Fórmula:C22H20Cl2N4O4Pureza:97% - 99.03%Forma y color:SolidPeso molecular:475.32UMI-77
CAS:<p>UMI-77 is a selective Mcl-1 inhibitor. UMI-77 binds to the BH3-binding groove of Mcl-1.Cost-effective and quality-assured.</p>Fórmula:C18H14BrNO5S2Pureza:96% - 99.57%Forma y color:SolidPeso molecular:468.34ACBI1
CAS:ACBI1 is a potent PROTAC degrader of BAF ATPase subunits SMARCA2 and SMARCA4, also degrades the polybromo-associated BAF (PBAF) complex member PBRM1, with DC50sFórmula:C49H58FN9O7SPureza:97.54% - 98.15%Forma y color:SolidPeso molecular:936.1[8]-Shogaol
CAS:[8]-Shogaol is a component of ginger and maintains anti-inflammatory activity as a cyclooxygenase-2 inhibitor.Fórmula:C19H28O3Pureza:97.01%Forma y color:SolidPeso molecular:304.42R-7050
CAS:<p>R-7050 (TNF-α Antagonist III), a tumor necrosis factor receptor (TNFR) antagonist, exhibits heightened selectivity for TNFα.</p>Fórmula:C16H8ClF3N4SPureza:98.64% - 99.8%Forma y color:SolidPeso molecular:380.77(+)-Nortrachelogenin
CAS:<p>(+)-Nortrachelogenin is a lignan isolated from Wikstroemia indica C.A. Meyer (Thymelaeaceae). (+)-Nortrachelogenin possesses antileukemic activity.</p>Fórmula:C20H22O7Pureza:99.88%Forma y color:SolidPeso molecular:374.38Cidofovir dihydrate
CAS:<p>Cidofovir dihydrate: Injectable anti-CMV; suppresses CMV by inhibiting viral DNA polymerase; treats CMV retinitis in AIDS.</p>Fórmula:C8H18N3O8PPureza:99.44%Forma y color:SolidPeso molecular:315.22Erdafitinib
CAS:<p>Erdafitinib (JNJ-42756493) is a quinoxaline derivative compound, acts on FGFR1/2/3/4.</p>Fórmula:C25H30N6O2Pureza:97.00% - 99.07%Forma y color:SolidPeso molecular:446.54ASK1-IN-1
CAS:ASK1-IN-1 inhibits apoptosis kinase 1, crucial in cell stress responses, with 21 nM IC50.Fórmula:C19H19N9O2Pureza:99.92%Forma y color:SolidPeso molecular:405.41Taurochenodeoxycholic Acid
CAS:<p>Taurochenodeoxycholic Acid (12-Deoxycholyltaurine) is one of the main bioactive substances of animals' bile acid.</p>Fórmula:C26H45NO6SPureza:99.53% - 99.86%Forma y color:SolidPeso molecular:499.7MGH-CP1
CAS:<p>MGH-CP1 inhibits TEAD2/4 auto-palmitoylation with IC50 of 710 and 672 nM, respectively.</p>Fórmula:C20H24N4OSPureza:98.66%Forma y color:SolidPeso molecular:368.5BAY 61-3606 dihydrochloride
CAS:<p>BAY 61-3606 dihydrochloride (BAY 61-3606) is a potent and selective inhibitor of Syk kinase (Ki = 7.5 nM).</p>Fórmula:C20H18N6O3·2HClPureza:99.46%Forma y color:SolidPeso molecular:463.32Lycorine
CAS:<p>Lycorine (Narcissine) inhibits protein synthesis and may inhibit ascorbic acid biosynthesis, although studies on the latter are controversial and inconclusive.</p>Fórmula:C16H17NO4Pureza:98.60% - 99.95%Forma y color:SolidPeso molecular:287.312BAct
CAS:<p>2BAct is a novel eif2b activator, preventing neurological defects caused by a chronic integrated stress response</p>Fórmula:C19H16ClF3N4O3Pureza:97.97% - 99.04%Forma y color:SolidPeso molecular:440.8Irigenin
CAS:<p>Irigenin mediates its antimetastatic effect by specifically and selectively blocking the α9β1 and α4β1 integrin binding sites on the C-C loop of the Extra</p>Fórmula:C18H16O8Pureza:99.50% - 99.85%Forma y color:SolidPeso molecular:360.31ML141
CAS:<p>ML141 (CID-2950007) is an effective, specific and reversible non-competitive inhibitor of Rho family GTPase cdc42 (IC50: 200 nM).</p>Fórmula:C22H21N3O3SPureza:99.36% - 99.56%Forma y color:SolidPeso molecular:407.49SW106065
CAS:<p>SW106065 is a novel pharmacologic inducer of apoptosis in MPNST (malignant peripheral nerve sheath tumors). SW106065 inhibits ATP consumption of sMPNST.</p>Fórmula:C10H8N2OSPureza:99.97%Forma y color:SolidPeso molecular:204.25(S)-(+)-Rolipram
CAS:(S)-(+)-Rolipram ((+)-Rolipram) inhibits human monocyte cyclic AMP-specific PDE4 with IC50 of 0.75 μM, has anti-inflammatory and anti-depressant activity in theFórmula:C16H21NO3Pureza:99.14%Forma y color:SolidPeso molecular:275.34Nur77 modulator 1
CAS:<p>Nur77 modulator 1: binds at 3.58 μM, boosts expression, alters location, triggers ER stress/autophagy, induces apoptosis, and fights hepatoma.</p>Fórmula:C28H25N5O2SPureza:99.62%Forma y color:SolidPeso molecular:495.6KRIBB11
CAS:<p>KRIBB11 is an inhibitor of Heat shock factor (HSF) inhibitor.</p>Fórmula:C13H12N6O2Pureza:97.25% - 99.91%Forma y color:SolidPeso molecular:284.27Asperosaponin VI
CAS:Asperosaponin VI, from Dipsacus asper rhizome, treats back pain, hematoma, and fractures.Fórmula:C47H76O18Pureza:97.15% - 99.79%Forma y color:SolidPeso molecular:929.10Ginsenoside Rg6
CAS:<p>Ginsenoside Rg6 inhibits the proliferation and induces apoptosis of human lymphoma JK cells</p>Fórmula:C42H70O12Pureza:97.34%Forma y color:SolidPeso molecular:767GSK2334470
CAS:<p>GSK2334470 is a novel PDK1 inhibitor (IC50: ~10 nM, in a cell-free assay), with no inhibitory at other close related AGC-kinases.</p>Fórmula:C25H34N8OPureza:99.57% - 99.87%Forma y color:SolidPeso molecular:462.59Dictamine
CAS:<p>Dictamine (Dectamine) shows anticholinesterase, anti-inflammatory, mutagenic, and has antimicrobial activity against bacteria and fungi.</p>Fórmula:C12H9NO2Pureza:99.72% - 99.889%Forma y color:SolidPeso molecular:199.21Masitinib
CAS:<p>Masitinib (AB1010) is a tyrosine-kinase inhibitor used in the treatment of mast cell tumors in animals, specifically dogs.</p>Fórmula:C28H30N6OSPureza:97.56% - >99.99%Forma y color:SolidPeso molecular:498.64RSL3
CAS:<p>View and buy RSL3 from TargetMol.RSL3 is a VDAC-independent ferroptosis activator.Cited in 10 publications.</p>Fórmula:C23H21ClN2O5Pureza:98% - 99.96%Forma y color:SolidPeso molecular:440.88Schisandrin C
CAS:<p>Schisandrin C (Wuweizisu-C) is a phytochemical lignan isolated from Schizandra chinensis Baill; shows anticancer-effects in human leukemia U937 cells.</p>Fórmula:C22H24O6Pureza:99.44% - 99.56%Forma y color:SolidPeso molecular:384.42WM-3835
CAS:<p>WM-3835, a specific KAT7 inhibitor, potently halts OS cell growth, migration, and induces apoptosis.</p>Fórmula:C20H17FN2O4SPureza:97.78% - 99.36%Forma y color:SolidPeso molecular:400.42Venetoclax
CAS:<p>Venetoclax (ABT-199) is a selective inhibitor of Bcl-2 (Ki < 0.010 nM), binding over 3 orders of magnitude less avidly to Bcl-xL, and Bcl-W (Kis = 48/245 nM).</p>Fórmula:C45H50ClN7O7SPureza:98.00% - 99.97%Forma y color:SolidPeso molecular:868.44Monomethyl auristatin E
CAS:Monomethyl auristatin E (MMAE) (MMAE), an antimitotic agent, inhibits cell division by blocking the polymerization of tubulin and also has inhibition ofFórmula:C39H67N5O7Pureza:98.47% - 99.9%Forma y color:SolidPeso molecular:717.98Limonin
CAS:<p>Limonin (Citrolimonin) is a triterpenoid enriched in citrus fruits, which has antivirus and antitumor ability.</p>Fórmula:C26H30O8Pureza:99.65% - 99.66%Forma y color:White To Slightly Off White PowderPeso molecular:470.51(-)-Huperzine A
CAS:<p>(-)-Huperzine A: Lycopodium alkaloid, AChE inhibitor, treats Alzheimer's in China.</p>Fórmula:C15H18N2OPureza:99.19% - >99.99%Forma y color:White To Slight White Crystaline PowderPeso molecular:242.32Zoledronic Acid
CAS:<p>Zoledronic Acid (ZOL 446) 是一种含氮二磷酸盐，能抑制破骨细胞的分化和凋亡，具有高效的抗骨质再吸收活性，也有抗癌作用。</p>Fórmula:C5H10N2O7P2Pureza:98% - 99.93%Forma y color:White Crystalline PowderPeso molecular:272.09Troglitazone
CAS:<p>Troglitazone (Romglizone) is a PPARγ agonist with anti-inflammatory and anti-tumor activity.</p>Fórmula:C24H27NO5SPureza:98% - 99.8%Forma y color:Yellow SolidPeso molecular:441.54KYP-2047
CAS:<p>KYP-2047 is a very potent, selective Prolyl oligopeptidase (POP) inhibitor.</p>Fórmula:C20H25N3O2Pureza:99.71%Forma y color:SolidPeso molecular:339.43Artemisitene
CAS:<p>Artemisitene, an oxidized antimalarial derivative of Artemisinin, stems from precursors like Artemisinin B and Artemisinic acid.</p>Fórmula:C15H20O5Pureza:99.58%Forma y color:SolidPeso molecular:280.32BAM7
CAS:<p>BAM 7 is a direct and specific activator of proapoptotic Bax (EC50: 3.3 μM).</p>Fórmula:C21H19N5O2SPureza:98.51% - 98.68%Forma y color:SolidPeso molecular:405.47Glyphosate
CAS:<p>Glyphosate (Atila) is an herbicide. It also is a possible carcinogen to humans.</p>Fórmula:C3H8NO5PPureza:99.12% - 99.91%Forma y color:White Crystals (Darkens) Ph (1% Solution In Water) 2 5 (Ntp 1992)Peso molecular:169.07GSK621
CAS:<p>GSK621 is a specific and potent AMPK activator.</p>Fórmula:C26H20ClN3O5Pureza:97.02% - 97.05%Forma y color:SolidPeso molecular:489.91Sodium Oxamate
CAS:<p>Sodium Oxamate (Oxamic acid sodium salt) is an LDH inhibitor that specifically inhibits LDHA.</p>Fórmula:C2H2NNaO3Pureza:99.23% - ≥98%Forma y color:White Crystalline PowderPeso molecular:111.03SC99
CAS:SC99 inhibits JAK2-STAT3, reducing STAT3 genes, platelet activity, and has anti-myeloma, anti-thrombotic effects.Fórmula:C15H8Cl2FN3OPureza:99.56%Forma y color:SolidPeso molecular:336.15Cichoric Acid
CAS:<p>Cichoric Acid (Dicaffeoyltartaric acid) is a potent inhibitor of human immunodeficiency virus type-1 (HIV-1) integrase and the replication in tissues.</p>Fórmula:C22H18O12Pureza:97.87% - 98.77%Forma y color:SolidPeso molecular:474.37BML-210
CAS:<p>BML-210 (CAY10433) is a new-type HDAC inhibitor.</p>Fórmula:C20H25N3O2Pureza:96.37% - 98.12%Forma y color:SolidPeso molecular:339.43Prosapogenin A
CAS:<p>Prosapogenin A (Progenin III) has anticancer activity.</p>Fórmula:C39H62O12Pureza:99.60% - 99.75%Forma y color:SolidPeso molecular:722.9
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