Apoptosis
Los inhibidores de la apoptosis son compuestos que previenen o retrasan el proceso de muerte celular programada, conocido como apoptosis. Estos inhibidores son vitales para estudiar los mecanismos de supervivencia celular y se utilizan para investigar enfermedades donde la apoptosis está desregulada, como el cáncer, los trastornos neurodegenerativos y las enfermedades autoinmunes. Al modular la apoptosis, estos inhibidores pueden ayudar en el desarrollo de terapias dirigidas a controlar la muerte celular. En CymitQuimica, ofrecemos una amplia selección de inhibidores de la apoptosis de alta calidad para apoyar su investigación en biología celular, oncología y campos relacionados.
Subcategorías de "Apoptosis"
- ASK(6 productos)
- BCL(11 productos)
- Caspasa(125 productos)
- FOXO1(3 productos)
- IAP(66 productos)
- Mdm2(12 productos)
- PD-1 / PD-L1(125 productos)
- PDK(9 productos)
- PERK(25 productos)
- Serina / treonina quinasa(15 productos)
- Survivin(13 productos)
- TNF(92 productos)
- c-RET(51 productos)
- p53(62 productos)
Mostrar 6 subcategorías más
Se han encontrado 5600 productos de "Apoptosis"
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Bufotalin
CAS:<p>1. Bufotalin (Bufotaline)e is a kind of poisonous secretions of toads.</p>Fórmula:C26H36O6Pureza:99.45% - 99.91%Forma y color:White To Off-White SolidPeso molecular:444.56RO8994
CAS:<p>RO8994: potent MDM2 spiroindolinone inhibitor, IC50: 20 nM (proliferation), 5 nM (binding).</p>Fórmula:C31H31Cl2FN4O4Pureza:99.31% - 99.44%Forma y color:SolidPeso molecular:613.51Tasisulam
CAS:<p>Tasisulam (LY573636) is an apoptosis inducer and an antitumor agent via the intrinsic pathway.</p>Fórmula:C11H6BrCl2NO3S2Pureza:99% - >99.99%Forma y color:SolidPeso molecular:415.11Alantolactone
CAS:<p>Alantolactone is a selective inhibitor of STAT3 that induces cancer-associated apoptosis and has antitumor activity.Cost-effective and quality-assured.</p>Fórmula:C15H20O2Pureza:99.02% - 99.66%Forma y color:Crystalline PowderPeso molecular:232.32Bomedemstat
CAS:<p>Bomedemstat (IMG-7289),Irreversible LSD1 inhibitor. Active in MPN models. Antineoplastic effects. Used in AML and myelofibrosis research.</p>Fórmula:C28H34FN7O2Pureza:99.00%Forma y color:SolidPeso molecular:519.61SKI V
CAS:<p>SKI V is a potent and noncompetitive non-lipid sphingosine kinase (SPHK; SK) inhibitor (GST-hSK,IC50 : 2 μM), and is a PI3K inhibitor(hPI3k,IC50 : 6 μM),</p>Fórmula:C15H10O4Pureza:98.78%Forma y color:SolidPeso molecular:254.24AG1024
CAS:<p>AG1024 (Tyrphostin) suppresses IGF-1R autophosphorylation(IC50=7 μM), and is less potent for IR(IC50=57 μM).</p>Fórmula:C14H13BrN2OPureza:98% - 99.37%Forma y color:SolidPeso molecular:305.17Epibrassinolide
CAS:<p>Epibrassinolide (BP55) (EBR) is a biologically active compound of the brassinosteroids, is a natural brassinosteroid (BR) derivative, is a plant regulator with</p>Fórmula:C28H48O6Pureza:97.57% - 98.11%Forma y color:SolidPeso molecular:480.68UAMC-3203 hydrochloride
CAS:<p>UAMC-3203 hydrochloride is a potent and selective Ferroptosis inhibitor with an IC50 of 12 nM.</p>Fórmula:C25H38ClN5O2SPureza:99.62%Forma y color:SolidPeso molecular:508.12PIK-75
CAS:<p>PIK-75, a DNA-PK and PI3K inhibitor, suppresses DNA-PK(IC50=2 nM), p110α(IC50=5.8 nM) and p110γ(IC50=76 nM).</p>Fórmula:C16H14BrN5O4SPureza:98.52% - >99.99%Forma y color:SolidPeso molecular:452.28Mocetinostat
CAS:<p>Mocetinostat (MG0103) is an orally available HDAC inhibitor with most potency for HDAC1 (IC50: 0.15 μM), 2- to 10- fold selectivity against HDAC2/3/11.</p>Fórmula:C23H20N6OPureza:99% - 99.21%Forma y color:SolidPeso molecular:396.44Ripretinib
CAS:<p>Ripretinib (DCC-2618) is an orally bioavailable inhibitor of KIT and PDGFRA.</p>Fórmula:C24H21BrFN5O2Pureza:99.07% - 99.38%Forma y color:SolidPeso molecular:510.36Levomenol
CAS:<p>Levomenol, or (-)-α-Bisabolol, is a sesquiterpene in aromatic plant oils with antioxidant, anti-inflammatory, and anti-apoptotic properties.</p>Fórmula:C15H26OPureza:96.01%Forma y color:Clear To Yellowish LiquidPeso molecular:222.37Baicalein monohydrate
CAS:<p>Baicalein monohydrate blocks 12-lipoxygenase, curbs leukotrienes, lysosomal enzymes, Ca2+ dynamics, and fights arthritis.</p>Fórmula:C15H12O6Forma y color:SolidPeso molecular:288.25PKR-IN-C16
CAS:<p>PKR-IN-C16: inhibits PKR autophosphorylation and translation blockade; binds ATP site; IC50 of 186-210 nM; protects cells from ER stress damage.</p>Fórmula:C13H8N4OSPureza:97.8%Forma y color:SolidPeso molecular:268.29Neferine
CAS:<p>Neferine: anti-tumor, enhances DOX efficacy, prevents diabetic vasculopathy; mediates via CYP3A4, GSH depletion, blocks ROS/Akt/NF-κB.</p>Fórmula:C38H44N2O6Pureza:98.81% - 99.65%Forma y color:SolidPeso molecular:624.77Momordin Ic
CAS:<p>Momordin Ic (Momordin 1c) might represent a potential anticancer activity, by inducing apoptosis through oxidative stress-regulated mitochondrial dysfunction</p>Fórmula:C41H64O13Pureza:98% - 99.69%Forma y color:SolidPeso molecular:764.94A-1331852
CAS:<p>A-1331852 is a potent and selectiveBCL-XL inhibitor and may be useful in the treatment of cancer, immune and autoimmune diseases.</p>Fórmula:C38H38N6O3SPureza:98.15% - >99.99%Forma y color:SolidPeso molecular:658.81BV6
CAS:<p>BV6 is an antagonist of c-IAP1 and XIAP, members of the inhibitors of apoptosis (IAP) family.</p>Fórmula:C70H96N10O8Pureza:97.46% - 99.82%Forma y color:SolidPeso molecular:1205.57Sal003
CAS:<p>Sal003, an effective cell-permeable analog, inhibitis the eIF2α phosphatase.</p>Fórmula:C18H15Cl4N3OSPureza:99.17% - 99.77%Forma y color:SolidPeso molecular:463.21Infigratinib
CAS:<p>Infigratinib (NVP-BGJ398) (BGJ398) is an orally bioavailable pan FGFR inhibitor (IC50: 0.9/1.4/1 nM for FGFR1/2/3), >40-fold selective for FGFR versus FGFR4 and</p>Fórmula:C26H31Cl2N7O3Pureza:98% - 98.97%Forma y color:SolidPeso molecular:560.48LCL161
CAS:<p>LCL161 is a SMAC mimetic, an IAP antagonist with oral activity that inhibits XIAP and cIAP1. LCL161 has potential antitumor activity. Cost-effective and quality-assured.</p>Fórmula:C26H33FN4O3SPureza:99.13% - 99.87%Forma y color:SolidPeso molecular:500.63Salvigenin
CAS:<p>Salvigenin is a potent hMAO-A inhibitor, has neuroprotective, antitumor and immunomodulatory effects.</p>Fórmula:C18H16O6Pureza:99.17% - 99.78%Forma y color:SolidPeso molecular:328.32Gardenin B
CAS:<p>Gardenin B exhibits superior antiproliferative activity against lung, breast, colon, hepatic and leukaemia cell lines as well as in keratinocytes .</p>Fórmula:C19H18O7Pureza:98.80% - 99.74%Forma y color:SolidPeso molecular:358.34Delanzomib
CAS:<p>Delanzomib (CEP-18770) is an oral proteasome inhibitor with an IC50 of 3.8 nM, targeting chymotrypsin-like activity with minimal effect on other activities.</p>Fórmula:C21H28BN3O5Pureza:95.52% - 99.46%Forma y color:SolidPeso molecular:413.28Telekin
CAS:<p>Telekin, a sesquiterpene lactone from Carpesium divaricatum, strongly inhibits cancer cell growth.</p>Fórmula:C15H20O3Pureza:99.86% - 99.97%Forma y color:SolidPeso molecular:248.32AT7519
CAS:<p>AT7519 is a CDK1/2/4/6/9 inhibitor (IC50: 10-210 nM). It is less effective to CDK3 and little active to CDK7.</p>Fórmula:C16H17Cl2N5O2Pureza:98.88% - 99.65%Forma y color:SolidPeso molecular:382.24Malabaricone B
CAS:<p>Malabaricone B is a Spice-derived phenolic, it induces mitochondrial damage in lung cancer cells via a p53-independent pathway.</p>Fórmula:C21H26O4Pureza:99.84% - 99.91%Forma y color:SolidPeso molecular:342.43(E/Z)-TG003
CAS:<p>(E/Z)-TG003 is a potent and ATP-competitive Cdc2-like kinase (Clk) inhibitor.</p>Fórmula:C13H15NO2SPureza:98% - 99.04%Forma y color:SolidPeso molecular:249.33ENMD-2076
CAS:<p>ENMD-2076, a multi-targeted kinase inhibitor, has specific activity against Aurora A, Flt3, KDR/VEGFR2, Flt4/VEGFR3, FGFR1, FGFR2, Src, PDGFRα.</p>Fórmula:C21H25N7Pureza:97.63% - ≥95%Forma y color:SolidPeso molecular:375.47m-3M3FBS
CAS:<p>m-3M3FBS is a phospholipase C (PLC) activator.</p>Fórmula:C16H16F3NO2SPureza:99.66%Forma y color:SolidPeso molecular:343.36Polygalacin D
CAS:<p>Polygalacin D shows anti- proliferation, anti-inflammary, and hepatoprotective activities, it can inhibit the expression of lipopolysaccharide (LPS)-induced</p>Fórmula:C57H92O27Pureza:98.95% - ≥98%Forma y color:SolidPeso molecular:1209.4Choline
CAS:<p>Choline is a ubiquitous water soluble nutrient, often associated with the B vitamins</p>Fórmula:C5H15NO2Pureza:99.97% - ≥98%Forma y color:LiquidPeso molecular:121.18MPTP hydrochloride
CAS:<p>MPTP hydrochloride is a precursor of MPP+, a dopamine neurotoxin with blood-brain barrier permeability.</p>Fórmula:C12H16ClNPureza:96.35% - >99.99%Forma y color:SolidPeso molecular:209.72CHR-6494 TFA
CAS:<p>CHR-6494 TFA: potent haspin inhibitor (IC50=2 nM), blocks H3T3 phosphorylation, triggers apoptosis in cancer cells. Used for cancer research.</p>Fórmula:C18H17F3N6O2Pureza:99.50%Forma y color:SolidPeso molecular:406.36Obatoclax Mesylate
CAS:Obatoclax Mesylate (GX15-070) is a Bcl-2 antagonist (Ki: 0.22 μM) and can induce apoptosis with up-regulation of Bim, induced cytochrome c release, andFórmula:C20H19N3O·CH4O3SPureza:99.58% - 99.88%Forma y color:SolidPeso molecular:413.49CCT007093
CAS:<p>CCT007093 is an effective PPM1D (WIP1) inhibitor (IC50: 8.4 μM).</p>Fórmula:C15H12OS2Pureza:98% - 99.88%Forma y color:SolidPeso molecular:272.39Temsirolimus
CAS:<p>Temsirolimus (CCI-779) is a specific mTOR inhibitor ( IC50: 1.76 μM), used in the treatment of advanced renal cell cancer.</p>Fórmula:C56H87NO16Pureza:97.76% - >99.99%Forma y color:White Crystalline PowderPeso molecular:1030.29Amantadine
CAS:<p>Amantadine (1-Aminoadamantane), an antiviral, is a weak antagonist of the NMDA-type glutamate receptor, increases dopamine release and blocks dopamine reuptake.</p>Fórmula:C10H17NPureza:99.73% - 99.94%Forma y color:Hexakistetrahedral Crystals By Sublimation SolidPeso molecular:151.25Inecalcitol
CAS:<p>Inecalcitol is a unique vitamin D3 analog that induces apoptosis and has anticancer activity.Cost-effective and quality-assured.</p>Fórmula:C26H40O3Pureza:99.96%Forma y color:SolidPeso molecular:400.59GSK1324726A
CAS:<p>GSK1324726A (I-BET726) is a greatly specific inhibitor of BET family proteins for BRD2(IC50=41 nM), BRD3(IC50=31 nM), and BRD4 (IC50=22 nM).</p>Fórmula:C25H23ClN2O3Pureza:98.34% - 99.85%Forma y color:SolidPeso molecular:434.91MPI-0479605
CAS:<p>MPI-0479605 is an ATP competitive and selective inhibitor.</p>Fórmula:C22H29N7OPureza:97.59% - >99.99%Forma y color:SolidPeso molecular:407.51(-)-Alkannin
CAS:<p>(-)-Alkannin (Shikonin) is a natural red naphthoquinone pigment, has antimicrobial, anti-tumor, and anti-inflammatory effects.</p>Fórmula:C16H16O5Pureza:98.18% - 98.8%Forma y color:White Or Slightly Yellow Crystalline Powder SolidPeso molecular:288.3Prosapogenin A
CAS:<p>Prosapogenin A (Progenin III) has anticancer activity.</p>Fórmula:C39H62O12Pureza:99.60% - 99.75%Forma y color:SolidPeso molecular:722.9Isocurcumenol
CAS:<p>1. Isocurcumenol inhibits 5α-reductase which converts testosterone to dihydrotestosterone (DHT).</p>Fórmula:C15H22O2Pureza:99.29% - ≥95%Forma y color:SolidPeso molecular:234.33UAMC-3203
CAS:<p>UAMC-3203 is a potent and selective Ferroptosis inhibitor (IC50: 12 nM).</p>Fórmula:C25H37N5O2SPureza:97.052% - 99.72%Forma y color:SolidPeso molecular:471.66C646
CAS:<p>C646, a histone acetyltransferase inhibitor, inhibits p300 (Ki: 400 nM, in a cell-free assay).</p>Fórmula:C24H19N3O6Pureza:98% - 99.21%Forma y color:SolidPeso molecular:445.42Aniline mustard
CAS:<p>Aniline mustard (Mesylerythrol) is alkylating mustard with anti-neoplastic activity.</p>Fórmula:C10H13Cl2NPureza:99.54%Forma y color:SolidPeso molecular:218.12Flurbiprofen Axetil
CAS:<p>Flurbiprofen Axetil (Lipfen) is an anti-inflammatory used as an analgesic.</p>Fórmula:C19H19FO4Pureza:97.58% - 98%Forma y color:SolidPeso molecular:330.359-Methoxycamptothecin
CAS:9-Methoxycamptothecin (MCPT) has antitumour activities through topoisomerase inhibition.Fórmula:C21H18N2O5Pureza:98.49% - 99.56%Forma y color:SolidPeso molecular:378.38
