Apoptosis
Los inhibidores de la apoptosis son compuestos que previenen o retrasan el proceso de muerte celular programada, conocido como apoptosis. Estos inhibidores son vitales para estudiar los mecanismos de supervivencia celular y se utilizan para investigar enfermedades donde la apoptosis está desregulada, como el cáncer, los trastornos neurodegenerativos y las enfermedades autoinmunes. Al modular la apoptosis, estos inhibidores pueden ayudar en el desarrollo de terapias dirigidas a controlar la muerte celular. En CymitQuimica, ofrecemos una amplia selección de inhibidores de la apoptosis de alta calidad para apoyar su investigación en biología celular, oncología y campos relacionados.
Subcategorías de "Apoptosis"
- ASK(6 productos)
- BCL(11 productos)
- Caspasa(125 productos)
- FOXO1(3 productos)
- IAP(66 productos)
- Mdm2(12 productos)
- PD-1 / PD-L1(125 productos)
- PDK(9 productos)
- PERK(25 productos)
- Serina / treonina quinasa(15 productos)
- Survivin(13 productos)
- TNF(92 productos)
- c-RET(51 productos)
- p53(62 productos)
Mostrar 6 subcategorías más
Se han encontrado 5600 productos de "Apoptosis"
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PI-1840
CAS:<p>PI-1840 is a reversible and selective chymotrypsin-like (CT-L) inhibitor, with little proteasome proteolytic effects on trypsin-like (T-L) and PGPH-L.</p>Fórmula:C22H26N4O3Pureza:98.82%Forma y color:SolidPeso molecular:394.472'-OMe-Guanosine
CAS:<p>2'-OMe-Guanosine is a modified nucleoside produced by the action of tRNA guanosine-2'-o-methyltransferase. 2'-OMe-Guanosine has a certain pro-apoptotic effect.</p>Fórmula:C11H15N5O5Pureza:99.93%Forma y color:White SolidPeso molecular:297.27Linderalactone
CAS:<p>1. Linderalactone showed significant inhibitory effects on superoxide anion generation by human neutrophils in response to fMLP/CB, values of IC5 is 8.48 μg/mL.</p>Fórmula:C15H16O3Pureza:99.79%Forma y color:SolidPeso molecular:244.29Poncirin
CAS:<p>Poncirin inhibits human gastric cancer cell growth and prevents fat formation while boosting bone density and improving structure in osteoporosis mice.</p>Fórmula:C28H34O14Pureza:99.89% - 99.92%Forma y color:SolidPeso molecular:594.56Mocetinostat
CAS:<p>Mocetinostat (MG0103) is an orally available HDAC inhibitor with most potency for HDAC1 (IC50: 0.15 μM), 2- to 10- fold selectivity against HDAC2/3/11.</p>Fórmula:C23H20N6OPureza:99% - 99.21%Forma y color:SolidPeso molecular:396.44Cucurbitacin IIb
CAS:<p>Cucurbitacin IIb is an active ingredient in Hemsleyadine, used to treat dysentery and other infections; it has anti-inflammatory effects.</p>Fórmula:C30H48O7Pureza:98.66% - >99.99%Forma y color:SolidPeso molecular:520.7Temsirolimus
CAS:<p>Temsirolimus (CCI-779) is a specific mTOR inhibitor ( IC50: 1.76 μM), used in the treatment of advanced renal cell cancer.</p>Fórmula:C56H87NO16Pureza:97.76% - >99.99%Forma y color:White Crystalline PowderPeso molecular:1030.29Calcimycin
CAS:<p>Calcimycin (A-23187) is a polyether antibiotic that transports Ca²⁺, uncouples phosphorylation, and inhibits ATPase in mitochondria.</p>Fórmula:C29H37N3O6Pureza:98%Forma y color:SolidPeso molecular:523.62Amantadine
CAS:<p>Amantadine (1-Aminoadamantane), an antiviral, is a weak antagonist of the NMDA-type glutamate receptor, increases dopamine release and blocks dopamine reuptake.</p>Fórmula:C10H17NPureza:99.73% - 99.94%Forma y color:Hexakistetrahedral Crystals By Sublimation SolidPeso molecular:151.25Inecalcitol
CAS:<p>Inecalcitol is a unique vitamin D3 analog that induces apoptosis and has anticancer activity.Cost-effective and quality-assured.</p>Fórmula:C26H40O3Pureza:99.96%Forma y color:SolidPeso molecular:400.59GSK1324726A
CAS:<p>GSK1324726A (I-BET726) is a greatly specific inhibitor of BET family proteins for BRD2(IC50=41 nM), BRD3(IC50=31 nM), and BRD4 (IC50=22 nM).</p>Fórmula:C25H23ClN2O3Pureza:98.34% - 99.85%Forma y color:SolidPeso molecular:434.91MAZ51
CAS:<p>MAZ51 is a VEGFR-3 (Flt-4) tyrosine kinase inhibitor.</p>Fórmula:C21H18N2OPureza:98.53%Forma y color:SolidPeso molecular:314.38MPI-0479605
CAS:<p>MPI-0479605 is an ATP competitive and selective inhibitor.</p>Fórmula:C22H29N7OPureza:97.59% - >99.99%Forma y color:SolidPeso molecular:407.51(-)-Alkannin
CAS:<p>(-)-Alkannin (Shikonin) is a natural red naphthoquinone pigment, has antimicrobial, anti-tumor, and anti-inflammatory effects.</p>Fórmula:C16H16O5Pureza:98.18% - 98.8%Forma y color:White Or Slightly Yellow Crystalline Powder SolidPeso molecular:288.3TVB-3166
CAS:<p>TVB-3166: reversible, selective FASN inhibitor, induces apoptosis, hinders xenograft growth (IC50: 42 nM FASN, 81 nM palmitate synthesis).</p>Fórmula:C24H24N4OPureza:99.53% - 99.57%Forma y color:SolidPeso molecular:384.47Sirtinol
CAS:<p>Sirtinol is a selective SIRT1/2 inhibitor (IC50: 131/38 μM).</p>Fórmula:C26H22N2O2Pureza:97.12% - 99.96%Forma y color:SolidPeso molecular:394.47Troglitazone
CAS:<p>Troglitazone (Romglizone) is a PPARγ agonist with anti-inflammatory and anti-tumor activity.</p>Fórmula:C24H27NO5SPureza:98% - 99.8%Forma y color:Yellow SolidPeso molecular:441.54C646
CAS:<p>C646, a histone acetyltransferase inhibitor, inhibits p300 (Ki: 400 nM, in a cell-free assay).</p>Fórmula:C24H19N3O6Pureza:98% - 99.21%Forma y color:SolidPeso molecular:445.42Embelin
CAS:<p>Embelin (Embelic acid), isolated from the Japanese Ardisia herb, is an inhibitor of the X-linked inhibitor of apoptosis (IC50: 4.1 uM).</p>Fórmula:C17H26O4Pureza:97.07% - 99.88%Forma y color:SolidPeso molecular:294.39Lexibulin
CAS:<p>Lexibulin (CYT-997)(CYT-997) is a potent tubulin polymerization inhibitor (IC50: 10-100 nM, in Y cell lines).</p>Fórmula:C24H30N6O2Pureza:98.87%Forma y color:SolidPeso molecular:434.53Fangchinoline
CAS:<p>Fangchinoline (Tetrandrine B) is extracted from Stephania tetrandra S. Moore.</p>Fórmula:C37H40N2O6Pureza:99.86% - >99.99%Forma y color:SolidPeso molecular:608.72JNJ-7706621
CAS:<p>JNJ-7706621 is a potent aurora kinase inhibitor, and also inhibits CDK1 and CDK2.</p>Fórmula:C15H12F2N6O3SPureza:99.1% - 99.85%Forma y color:SolidPeso molecular:394.363-Bromopyruvic acid
CAS:<p>3-Bromopyruvic acid (Hexokinase II Inhibitor II, 3-BP) is a hexokinase II inhibitor with Ki of 2.4 mM for glycolysis/hexokinase inhibition.</p>Fórmula:C3H3BrO3Pureza:95% - 99.644%Forma y color:White To Pale Yellow Crystalline PowderPeso molecular:166.96Aniline mustard
CAS:<p>Aniline mustard (Mesylerythrol) is alkylating mustard with anti-neoplastic activity.</p>Fórmula:C10H13Cl2NPureza:99.54%Forma y color:SolidPeso molecular:218.12Flurbiprofen Axetil
CAS:<p>Flurbiprofen Axetil (Lipfen) is an anti-inflammatory used as an analgesic.</p>Fórmula:C19H19FO4Pureza:97.58% - 98%Forma y color:SolidPeso molecular:330.359-Methoxycamptothecin
CAS:9-Methoxycamptothecin (MCPT) has antitumour activities through topoisomerase inhibition.Fórmula:C21H18N2O5Pureza:98.49% - 99.56%Forma y color:SolidPeso molecular:378.38Radotinib
CAS:<p>Radotinib (IY-5511), and sometimes referred to by its investigational name IY5511, is a drug for the treatment of different types of Y, most notably</p>Fórmula:C27H21F3N8OPureza:99.13% - 99.97%Forma y color:SolidPeso molecular:530.5NSC 73150
CAS:<p>6-Methyl-1H-pyrimidin-4-one (NSC 73150) shows antitumor effects, impeding growth in breast, lung, liver cancer, and inducing apoptosis.</p>Fórmula:C12H12N4O2Pureza:99.84%Forma y color:SolidPeso molecular:244.25CPI1189
CAS:<p>CPI1189 (REN-1189) is a TNF-a release inhibitor potentially for the treatment of sciatica and postherpetic neuralgia.</p>Fórmula:C13H18N2O2Pureza:98.34% - 99.51%Forma y color:SolidPeso molecular:234.29Calpeptin
CAS:<p>Calpeptin is a potent, cell-permeable calpain inhibitor.</p>Fórmula:C20H30N2O4Pureza:97.06% - 98.33%Forma y color:White To Off-White PowderPeso molecular:362.46Y-27632
CAS:<p>Y-27632 (Y-27632) is an orally potent, ATP-competitive inhibitor of ROCK-I and ROCK-II.</p>Fórmula:C14H21N3OPureza:99.53% - 99.87%Forma y color:SolidPeso molecular:247.34Ispinesib
CAS:<p>Ispinesib (SB-715992), a selective, effectvie and reversible inhibitor of kinesin spindle protein (KSP), is derived from quinazolinone, with antineoplastic</p>Fórmula:C30H33ClN4O2Pureza:98% - 99.09%Forma y color:SolidPeso molecular:517.06BMS-833923
CAS:<p>BMS-833923 (XL-139), an orally bioavailable Smoothened antagonist, inhibits BODIPY cyclopamine binding to SMO in a dose-dependent manner (IC50: 21 nM).</p>Fórmula:C30H27N5OPureza:99.47% - 99.76%Forma y color:SolidPeso molecular:473.574E1rcat
CAS:<p>4E1RCat is a dual inhibitor of eIF4E:eIF4 g and eIF4E:4E-BP1 interaction. And it inhibits the binding of eIF4 g to eIF4E with IC50 of 3.2 μM.</p>Fórmula:C28H18N2O6Pureza:99.47%Forma y color:SolidPeso molecular:478.45EI1
CAS:<p>EI1 (Ezh2 inhibitor) is a potent and selective EZH2 inhibitor with IC50 of 15 nM and 13 nM for EZH2 (WT) and EZH2 (Y641F), respectively.</p>Fórmula:C23H26N4O2Pureza:99.93%Forma y color:SolidPeso molecular:390.484-MMPB
CAS:<p>15-Lipoxygenase Inhibitor 1 is a selective inhibitor of 15-lipoxygenase, with an IC50 of 18 μM.</p>Fórmula:C16H19N5SPureza:97.18%Forma y color:SolidPeso molecular:313.42pimpinellin
CAS:<p>Pimpinellin is a natural product that acts as antagonist of proteins with GABA receptor activity.</p>Fórmula:C13H10O5Pureza:99.85% - ≥95%Forma y color:SolidPeso molecular:246.22β-Lapachone
CAS:<p>β-Lapachone (ARQ-501) is a specific DNA topoisomerase I inhibitor, and no inhibitory activities against DNA topoisomerase II or ligase.</p>Fórmula:C15H14O3Pureza:99.76% - 99.88%Forma y color:SolidPeso molecular:242.27MX69
CAS:<p>MX69 is the MDM2/XIAP inhibitor, blocking the MDM2 protein-XIAP RNA interaction, leading to MDM2 degradation.</p>Fórmula:C27H26N2O4SPureza:97.27% - 99.57%Forma y color:SolidPeso molecular:474.57Isatin
CAS:<p>Isatin (2,3-Indolinedione) is an endogenous MAO inhibitor.</p>Fórmula:C8H5NO2Pureza:98.92%Forma y color:Yellow To Reddish Crystalline SolidPeso molecular:147.13Bay 11-7085
CAS:<p>Bay 11-7085 can irreversibly inhibit the IκBα phosphorylation induced by TNFα (IC50: 10 μM).</p>Fórmula:C13H15NO2SPureza:99.76% - 99.94%Forma y color:White SolidPeso molecular:249.33BDA-366
CAS:<p>BDA-366, a potent Bcl2 antagonist, selectively binds the Bcl2-BH4 domain with high affinity (Ki = 3.3 nM), inducing a conformational change that nullifies its</p>Fórmula:C24H29N3O4Pureza:98.61%Forma y color:SoildPeso molecular:423.5Zoledronic Acid
CAS:<p>Zoledronic Acid (ZOL 446) 是一种含氮二磷酸盐，能抑制破骨细胞的分化和凋亡，具有高效的抗骨质再吸收活性，也有抗癌作用。</p>Fórmula:C5H10N2O7P2Pureza:98% - 99.93%Forma y color:White Crystalline PowderPeso molecular:272.09R1530
CAS:<p>R1530 is a multikinase inhibitor with antineoplastic and antiangiogenesis activities.</p>Fórmula:C18H14ClFN4OPureza:98.422%Forma y color:SolidPeso molecular:356.783BDO
CAS:<p>3BDO is a new mTOR activator. 3BDO inhibits autophagy.</p>Fórmula:C18H17NO5Pureza:97.76%Forma y color:SolidPeso molecular:327.33Betulin
CAS:<p>Betulin (betulinol) (lup-20(29)-ene-3β, 28-diol) is an abundant, naturally occurring triterpene.</p>Fórmula:C30H50O2Pureza:98.52% - 99.88%Forma y color:White Crystalline PowderPeso molecular:442.72UNC1215
CAS:<p>UNC1215, a potent MBT antagonist, targets L3MBTL3 with high selectivity (IC50: 40 nM, Kd: 120 nM, 50x versus MBT family).</p>Fórmula:C32H43N5O2Pureza:98% - 99.04%Forma y color:SolidPeso molecular:529.72Sodium dichloroacetate
CAS:<p>Sodium dichloroacetate (BCA) inhibits PDK (IC50: 183 μM PDK2, 80 μM PDK4), triggers cancer cell apoptosis, and impedes tumor growth.</p>Fórmula:C2HCl2NaO2Pureza:99.32% - 99.87%Forma y color:White PowderPeso molecular:150.92ILK-IN-2
CAS:<p>ILK-IN-2 (OSU-T315) is a novel potent, orally active ILK (integrin-linked kinase) inhibitor with IC50 of 0.6 μM.</p>Fórmula:C30H30F3N5OPureza:99.30%Forma y color:SolidPeso molecular:533.59AES-350
CAS:<p>AES-350, an HDAC6 inhibitor (IC50: 0.0244 μM), also targets HDAC-3, -8, -11, induces AML cell apoptosis, and aids AML research.</p>Fórmula:C18H20N2O3Pureza:98.82%Forma y color:SolidPeso molecular:312.36
