Apoptosis
Los inhibidores de la apoptosis son compuestos que previenen o retrasan el proceso de muerte celular programada, conocido como apoptosis. Estos inhibidores son vitales para estudiar los mecanismos de supervivencia celular y se utilizan para investigar enfermedades donde la apoptosis está desregulada, como el cáncer, los trastornos neurodegenerativos y las enfermedades autoinmunes. Al modular la apoptosis, estos inhibidores pueden ayudar en el desarrollo de terapias dirigidas a controlar la muerte celular. En CymitQuimica, ofrecemos una amplia selección de inhibidores de la apoptosis de alta calidad para apoyar su investigación en biología celular, oncología y campos relacionados.
Subcategorías de "Apoptosis"
- ASK(6 productos)
- BCL(11 productos)
- Caspasa(127 productos)
- FOXO1(3 productos)
- IAP(66 productos)
- Mdm2(12 productos)
- PD-1 / PD-L1(126 productos)
- PDK(9 productos)
- PERK(23 productos)
- Serina / treonina quinasa(15 productos)
- Survivin(13 productos)
- TNF(91 productos)
- c-RET(51 productos)
- p53(62 productos)
Mostrar 6 subcategorías más
Se han encontrado 5618 productos de "Apoptosis"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
Tetrahydroxyquinone monohydrate
CAS:<p>Anticataract compound; redox-active; forms ROS via semiquinone radical cycle.</p>Fórmula:C6H6O7Forma y color:SolidPeso molecular:190.11PS 48
CAS:<p>PS 48 has been shown to be a PKB Kinase (PDK1) activator (Kd: 10.3 μM). This compound selectively binds to the PIF-binding pocket of PKB Kinase (PDK1).</p>Fórmula:C17H15ClO2Pureza:99.96% - ≥95%Forma y color:SolidPeso molecular:286.75GW 441756
CAS:GW 441756 is a specific Tropomyosin-related kinase A (TrkA) inhibitor with an IC50 value of 2 nM.Fórmula:C17H13N3OPureza:97.73% - 99.8%Forma y color:SolidPeso molecular:275.3Dubermatinib
CAS:<p>Dubermatinib (TP0903) is a potent and selective Axl kinase inhibitor.</p>Fórmula:C24H30ClN7O2SPureza:98.65% - 99.58%Forma y color:SolidPeso molecular:516.06B-AP15
CAS:<p>B-AP15 (NSC-687852) selectively inhibits 26S proteasome enzymes Usp14 and UCHL5, blocking their activity.</p>Fórmula:C22H17N3O6Pureza:91.43% - 98.77%Forma y color:SolidPeso molecular:419.39Apocynin
CAS:<p>Apocynin (NSC 2146) is a specific NADPH-oxidase inhibitor (IC50: 10 μM).</p>Fórmula:C9H10O3Pureza:99.71% - 99.98%Forma y color:Yellowish To Brown PowderPeso molecular:166.17Alda-1
CAS:<p>Alda-1 activates ALDH2*1 and ALDH2*2, permeates cells, and targets mitochondrial aldehyde dehydrogenase 2.</p>Fórmula:C15H11Cl2NO3Pureza:98.5% - 99.63%Forma y color:SolidPeso molecular:324.16GSK 872 hydrochloride
CAS:<p>GSK872 HCl（1346546-69-7 free base） (GSK2399872A) is an effective and specific RIP3 kinase inhibitor.</p>Fórmula:C19H18ClN3O2S2Pureza:99%Forma y color:SolidPeso molecular:419.94BC-1258
CAS:<p>BC-1258 is a unique small molecule F-box/LRR-repeat protein 2 (FBXL2) activator.</p>Fórmula:C22H22N4S2Pureza:97.48% - 99.64%Forma y color:SolidPeso molecular:406.57Metamizole magnesium
CAS:<p>Metamizole magnesium (Metamizolemagnesiumsalt) is a pain reliever, which can antispasmodic.</p>Fórmula:C26H32MgN6O8S2Pureza:93.51%Forma y color:SolidPeso molecular:645.01ARRY 520 hydrochloride
CAS:<p>'ARRY 520 hydrochloride: a KSP inhibitor causing apoptosis and strong anti-proliferative effects.'</p>Fórmula:C20H23ClF2N4O2SPureza:98.06% - 99.62%Forma y color:SolidPeso molecular:456.94Oleic acid
CAS:<p>Oleic acid, a common unsaturated fat, is used in oleates, lotions, and as a pharma solvent.</p>Fórmula:C18H34O2Pureza:97.14% - 99.91%Forma y color:Colorless Or Nearly Colorless Liq (Above 5-7 Deg C) Oleic Acid Is A Colorless To Pale Yellow Liquid With A Mild Odor Floats On Water (Uscg 1999)Peso molecular:282.46Serdemetan
CAS:<p>Serdemetan (JNJ-26854165) is an orally bioavailable HDM2 antagonist with potential antineoplastic activity.</p>Fórmula:C21H20N4Pureza:98% - 99.51%Forma y color:SolidPeso molecular:328.41L-685458
CAS:<p>L-685458 (L-685,458) is a specific and potent inhibitor of A beta PP gamma-secretase activity with Ki of 17 nM.</p>Fórmula:C39H52N4O6Pureza:99.62% - 99.80%Forma y color:SolidPeso molecular:672.85Eltrombopag Olamine
CAS:<p>Eltrombopag Olamine (Eltrombopag diethanolamine salt) is the orally active ethanolamine salt of eltrombopag, a small-molecule, nonpeptide thrombopoietin</p>Fórmula:C29H36N6O6Pureza:99.59% - 99.89%Forma y color:SolidPeso molecular:564.63SJ-172550
CAS:SJ-172550 is a small molecule inhibitor of MDMX (EC50: 5 μM).Fórmula:C22H21ClN2O5Pureza:99.87%Forma y color:SolidPeso molecular:428.87C-DIM12
CAS:<p>C-DIM12 boosts Nurr1 gene expression, heightens Nurr1 protein in neurons, and improves survival against 6-OHDA.</p>Fórmula:C23H17ClN2Pureza:97.72% - ≥95%Forma y color:SolidPeso molecular:356.85CI-1040
CAS:<p>CI-1040 (PD 184352) (PD184352) is an ATP non-competitive MEK1/2 inhibitor (IC50: 17 nM).</p>Fórmula:C17H14ClF2IN2O2Pureza:99.64%Forma y color:Off-White To Pale Beige SolidPeso molecular:478.66COTI-2
CAS:<p>COTI-2, an orally available thiosemicarbazone, is an activator of mutant forms of the p53 protein with potential antineoplastic activity.</p>Fórmula:C19H22N6SPureza:99% - 99.55%Forma y color:SolidPeso molecular:366.48BTZO-1
CAS:<p>BTZO-1 is an antioxidant response element (ARE) activator with cardioprotective activity.</p>Fórmula:C13H8N2OSPureza:99.46%Forma y color:SolidPeso molecular:240.28ASP3026
CAS:<p>ASP3026 has been used in trials studying the treatment of Solid Tumor, B-Cell Lymphoma, Advanced Malignancies,and Positive for Anaplastic Lymphoma Kinase.</p>Fórmula:C29H40N8O3SPureza:98.78% - 99.81%Forma y color:SolidPeso molecular:580.74HA15
CAS:<p>HA15 targets BiP/GRP78/HSPA5, showing anti-cancer effects on all tested melanoma cells, resistant or patient-derived.</p>Fórmula:C23H22N4O3S2Pureza:99.77% - 99.86%Forma y color:SolidPeso molecular:466.58α-Thujone
CAS:<p>α-Thujone is an inhibitor of ACh with an IC50 value of 24.7μM.</p>Fórmula:C10H16OPureza:97.02% - 98.41%Forma y color:Less Or Almost Colorless Liquid With A Menthol- Like Odor (Albert-Puleo 1978; Budavari 1996) Colorless Or Almost Colorless Liquid With A Menthol- Like Odor (Albert-Puleo 1978; Budavari 1996)Peso molecular:152.23Phenazine methylsulfate
CAS:<p>Phenazine methylsulfate is anti-bacterial agents.</p>Fórmula:C14H14N2O4SPureza:97.67% - >99.99%Forma y color:Yellow CrystallinePeso molecular:306.34ISRIB (trans-isomer)
CAS:<p>ISRIB (trans-isomer) is a potent inhibitor of PERK that rescues protein translation and prevents SG formation in the presence of P-eIF2α. Cost effective and quality assured.</p>Fórmula:C22H24Cl2N2O4Pureza:97.86% - 99.27%Forma y color:SolidPeso molecular:451.341A-116
CAS:<p>1A-116 is a specific Rac1 inhibitor.</p>Fórmula:C16H16F3N3Pureza:99.71%Forma y color:SolidPeso molecular:307.31Thalidomide 4-fluoride
CAS:<p>Thalidomide 4-fluoride (E3 ligase Ligand 4) (Cereblon ligand 4) is the Thalidomide-based Cereblon ligand.</p>Fórmula:C13H9FN2O4Pureza:99.12%Forma y color:SolidPeso molecular:276.22Etomoxir sodium salt
CAS:<p>Etomoxir sodium salt ((R)-Etomoxir sodium salt) is a carnitine palmitoyltransferase 1a (CPT-1a) inhibitor that blocks fatty acid synthesis.</p>Fórmula:C15H18ClO4·NaPureza:99.34% - 99.82%Forma y color:SolidPeso molecular:320.74Thalidomide-O-amido-C6-NH2 hydrochloride
CAS:<p>Thalidomide-O-amido-C6-NH2 HCl, a cereblon ligand-linker for PROTAC synthesis.</p>Fórmula:C21H27ClN4O6Pureza:97.33%Forma y color:SolidPeso molecular:466.915PHA-767491 hydrochloride
CAS:<p>PHA-767491 (CAY-10572) is a potent Cdc7/CDK9 inhibitor (IC50: 10/34 nM), selective against GSK3-β, CDK1/2, CDK5, MK2, CHK2, PLK1.</p>Fórmula:C12H12ClN3OPureza:99.56% - 99.92%Forma y color:SolidPeso molecular:249.69CA-4948
CAS:<p>CA-4948 (Emavusertib) is a potent IRAK4/FLT3 inhibtor. CA-4948 with anti-tumor activity.</p>Fórmula:C24H25N7O5Pureza:99.35% - 99.88%Forma y color:SolidPeso molecular:491.5Tenovin-6
CAS:<p>Tenovin-6 is a p53 transcriptional activity agonist.</p>Fórmula:C25H34N4O2SPureza:97.71% - >99.99%Forma y color:SolidPeso molecular:454.63Mimosine
CAS:<p>L-Mimosine (Leucenol) is an antineoplastic alanine-substituted pyridine derivative isolated from Leucena glauca and acts as an iron chelator.</p>Fórmula:C8H10N2O4Pureza:99.2% - 99.84%Forma y color:Crystals From Water SolidPeso molecular:198.18Dacarbazine citrate
CAS:<p>Dacarbazine citrate treats lymphatic cancers, malignant melanoma, islet cell carcinoma, and soft tissue sarcoma.</p>Fórmula:C12H18N6O8Forma y color:SolidPeso molecular:374.31ASK1-IN-2
CAS:<p>ASK1-IN-2: oral ASK1 inhibitor, IC50 32.8 nM, potential ulcerative colitis treatment.</p>Fórmula:C19H17FN6OPureza:98.79%Forma y color:SolidPeso molecular:364.38Rottlerin
CAS:<p>Rottlerin (NSC-56346), a Mallotus Philippinensis extract, inhibits PKC (3-100 μM IC50); triggers apoptosis by activating caspase 3.</p>Fórmula:C30H28O8Pureza:97.41% - 99.44%Forma y color:Orange To Brown PowderPeso molecular:516.54ZM-447439
CAS:<p>ZM 447439 selectively inhibits Aurora A/B (IC50: 110/130 nM); 8x less effective on MEK1, Src, Lck; minimal impact on CDK1/2/4, Plk1, Chk1.</p>Fórmula:C29H31N5O4Pureza:99.11% - 99.59%Forma y color:Pale Yellow SolidPeso molecular:513.59FOXO4-DRI acetate
<p>FOXO4-DRI acetate is a bioactive chemical.</p>Fórmula:C36H64N14O14SPureza:99.10%Forma y color:SolidPeso molecular:5358.06Rosiglitazone hydrochloride
CAS:<p>Rosiglitazone hydrochloride (BRL-49653 HCl) is a blood glucose-lowering drugs, stimulating insulin secretion by binding to the PPAR receptors in fat cells.</p>Fórmula:C18H19N3O3S·HClPureza:99.63% - 99.79%Forma y color:SolidPeso molecular:393.89Periplocin
CAS:<p>Periplocin fights lung cancer, induces apoptosis, stunts growth via beta-catenin/Tcf, and treats rheumatoid arthritis/traditional ailments.</p>Fórmula:C36H56O13Pureza:99.66% - 99.74%Forma y color:SolidPeso molecular:696.82INH1
CAS:INH1 (IBT13131) is a cell-permeable Hec1 inhibitor that specifically disrupts the Hec1/Nek2 interaction.Fórmula:C18H16N2OSPureza:99.80%Forma y color:SolidPeso molecular:308.45-Geranoxy-7-methoxycoumarin
CAS:<p>5-Geranoxy-7-methoxycoumarin shows antifungal activity.</p>Fórmula:C20H24O4Pureza:98.94% - 99.99%Forma y color:SolidPeso molecular:328.4NSC 23766 trihydrochloride
CAS:<p>NSC 23766 trihydrochloride (Rac1 Inhibitor) is an inhibitor of Rac GTPase targeting Rac activation by GEFs; no inhibitory for RhoA or Cdc42.</p>Fórmula:C24H35N7·3HClPureza:96.48% - 99.54%Forma y color:SolidPeso molecular:530.96TrxR1-IN-B19
CAS:<p>TrxR1-IN-B19 (TrxR1 IN B19), a TrxR1 inhibitor, selectively kills gastric cancer cells by a small molecule via targeting TrxR1 and ROS-mediated ER stress</p>Fórmula:C21H22O5Pureza:98.6%Forma y color:SolidPeso molecular:354.4Scopoletin
CAS:<p>Scopoletin (Esculetin 6-methyl ether) is a plant growth factor derived from the root of Scopolia carniolica, inhibits of acetylcholinesterase (AChE).</p>Fórmula:C10H8O4Pureza:97.06% - 99.88%Forma y color:Yellow To Beige Crystalline PowderPeso molecular:192.17Thalidomide-O-amido-C3-NH2 TFA
CAS:<p>Thalidomide-based E3 ligase linker for PROTAC tech; cereblon ligand conjugate.</p>Fórmula:C20H21F3N4O8Pureza:98.47%Forma y color:SolidPeso molecular:502.4Thalidomide-O-COOH
CAS:<p>Thalidomide-O-COOH is a Cereblon ligand for CRBN protein recruitment and PROTAC construction with a linker.</p>Fórmula:C15H12N2O7Pureza:98% - 98.29%Forma y color:SolidPeso molecular:332.27HS-1793
CAS:<p>HS-1793, resveratrol-like, reduces HIF-1, VEGF in hypoxia, and curbs human breast cancer growth in mouse model.</p>Fórmula:C16H12O3Pureza:98.16% - 99.82%Forma y color:SolidPeso molecular:252.26Garcinol
CAS:<p>Garcinol: inhibits HATs/PCAF (IC50=7/5 μM), anti-inflammatory, anti-cancer, anti-cholinesterase (AChE IC50=0.66 μM, BChE IC50=7.39 μM).</p>Fórmula:C38H50O6Pureza:98.59%Forma y color:SolidPeso molecular:602.8MK-8745
CAS:<p>MK-8745 is a potent and selective Aurora A inhibitor.</p>Fórmula:C20H19ClFN5OSPureza:99.09% - 99.79%Forma y color:SolidPeso molecular:431.91
