Apoptosis
Los inhibidores de la apoptosis son compuestos que previenen o retrasan el proceso de muerte celular programada, conocido como apoptosis. Estos inhibidores son vitales para estudiar los mecanismos de supervivencia celular y se utilizan para investigar enfermedades donde la apoptosis está desregulada, como el cáncer, los trastornos neurodegenerativos y las enfermedades autoinmunes. Al modular la apoptosis, estos inhibidores pueden ayudar en el desarrollo de terapias dirigidas a controlar la muerte celular. En CymitQuimica, ofrecemos una amplia selección de inhibidores de la apoptosis de alta calidad para apoyar su investigación en biología celular, oncología y campos relacionados.
Subcategorías de "Apoptosis"
- ASK(6 productos)
- BCL(11 productos)
- Caspasa(127 productos)
- FOXO1(3 productos)
- IAP(65 productos)
- Mdm2(12 productos)
- PD-1 / PD-L1(126 productos)
- PDK(9 productos)
- PERK(24 productos)
- Serina / treonina quinasa(15 productos)
- Survivin(13 productos)
- TNF(91 productos)
- c-RET(51 productos)
- p53(62 productos)
Mostrar 6 subcategorías más
Se han encontrado 5622 productos de "Apoptosis"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
YH239-EE
CAS:<p>YH239-EE, the ethyl ester of YH239, is a potent p53-MDM2 antagonist and an apoptosis inducer.</p>Fórmula:C25H27Cl2N3O4Pureza:99.61%Forma y color:SolidPeso molecular:504.41Infigratinib
CAS:<p>Infigratinib (NVP-BGJ398) (BGJ398) is an orally bioavailable pan FGFR inhibitor (IC50: 0.9/1.4/1 nM for FGFR1/2/3), >40-fold selective for FGFR versus FGFR4 and</p>Fórmula:C26H31Cl2N7O3Pureza:98% - 98.97%Forma y color:SolidPeso molecular:560.48Carfilzomib
CAS:<p>Carfilzomib (PR-171) is a proteasome inhibitor that irreversibly binds to the chymotrypsin of the 20S proteasome.</p>Fórmula:C40H57N5O7Pureza:99.6% - 99.84%Forma y color:SolidPeso molecular:719.91Orantinib
CAS:<p>Orantinib (NSC 702827) , a excellent effective against PDGFR autophosphorylation with Ki of 8 nM, also highly inhibits Flk-1 and FGFR1 trans-phosphorylation.</p>Fórmula:C18H18N2O3Pureza:98.92% - 99.52%Forma y color:SolidPeso molecular:310.35LY-411575
CAS:<p>LY-411575, a potent γ-secretase inhibitor, is with IC50 of 0.078 nM in the membrane and 0.082 nM in cell-based. It also suppresses Notch clevage.</p>Fórmula:C26H23F2N3O4Pureza:97.03% - 99.38%Forma y color:SolidPeso molecular:479.48K-Ras(G12C) inhibitor 12
CAS:<p>K-Ras(G12C) inhibitor 12 is an allosteric inhibitor of oncogenic K-Ras(G12C).</p>Fórmula:C15H17ClIN3O3Pureza:97.16%Forma y color:SolidPeso molecular:449.67(Rac)-Idroxioleic acid
CAS:<p>(Rac)-Idroxioleic acid (2-Hydroxyoleic acid) is a fatty acid amide hydrolase inhibitor with anti-tumor effect.</p>Fórmula:C18H34O3Pureza:≥98%Forma y color:SolidPeso molecular:298.46(20S)-Protopanaxatriol
CAS:<p>(20S)-Protopanaxatriol (g-PPT)(g-PPT), a metabolite of ginsenoside, could regulate endothelial cell functions through the estrogen receptor and glucocorticoid</p>Fórmula:C30H52O4Pureza:95% - 99%Forma y color:SolidPeso molecular:476.73DMU-212
CAS:<p>DMU-212, a Resveratrol derivative, has antimitotic, antiproliferative, antioxidant properties; induces apoptosis via ERK1/2.</p>Fórmula:C18H20O4Pureza:99.86%Forma y color:SolidPeso molecular:300.35Toddaculin
CAS:<p>Toddaculine may be beneficial for the prevention and treatment of osteoporosis, it can not only inhibit the differentiation of osteoclasts via activation of the</p>Fórmula:C16H18O4Pureza:99.91%Forma y color:SolidPeso molecular:274.31LDN-57444
CAS:<p>LDN-57444 is a reversible, competitive proteasome Uch-L1 inhibitor(IC50=0.88 μM) .</p>Fórmula:C17H11Cl3N2O3Pureza:97.8% - 99.87%Forma y color:SolidPeso molecular:397.64Quinidine sulfate dihydrate
CAS:<p>Quinidine sulfate dihydrate (Pitayine Sodium) is a potent and selective cytochrome P450db inhibitor</p>Fórmula:C40H54N4O10SPureza:99.85%Forma y color:White To Light Yellow Crystal PowdePeso molecular:782.9Capmatinib 2HCl.H2O
CAS:Capmatinib 2HCl.H2O (NVP-INC280 2HCl.H2O) is an orally bioavailable inhibitor of the proto-oncogene c-Met (HGFR)with potential antineoplastic activity.Fórmula:C23H21Cl2FN6O2Pureza:99.77%Forma y color:SolidPeso molecular:503.36Zoledronic acid monohydrate
CAS:<p>Zoledronic acid monohydrate (CGP 42446) is a synthetic imidazole bisphosphonate analog with anti-bone-resorption activity.</p>Fórmula:C5H12N2O8P2Pureza:99.91%Forma y color:White To Off-White PowderPeso molecular:290.1Prosapogenin A
CAS:<p>Prosapogenin A (Progenin III) has anticancer activity.</p>Fórmula:C39H62O12Pureza:99.60% - 99.75%Forma y color:SolidPeso molecular:722.9MK-8745
CAS:<p>MK-8745 is a potent and selective Aurora A inhibitor.</p>Fórmula:C20H19ClFN5OSPureza:99.09% - 99.79%Forma y color:SolidPeso molecular:431.91Epoxomicin
CAS:<p>Epoxomicin, a selective proteasome inhibitor, chiefly blocks CH-L activity, mildly affecting T-L and PGPH at lower rates.</p>Fórmula:C28H50N4O7Pureza:98.65% - 98.86%Forma y color:White To Off-White SolidPeso molecular:554.72Epieriocalyxin A
CAS:<p>Epieriocalyxin A can suppress Caco-2 colon cancer cell growth. It could be a potential drug for colon cancer therapy in the future.</p>Fórmula:C20H24O5Pureza:97.00%Forma y color:SolidPeso molecular:344.4RAF265
CAS:<p>RAF265 (CHIR-265) inhibits C-Raf/B-Raf/V600E (IC50: 3-60 nM), blocks VEGFR2 (EC50: 30 nM), in Phase 2 trials.</p>Fórmula:C24H16F6N6OPureza:99.56%Forma y color:SolidPeso molecular:518.41Isoalantolactone
CAS:<p>Isoalantolactone (Isohelenin), isolated from Inula spp., can inhibit the growth of several types of Y cells.</p>Fórmula:C15H20O2Pureza:99.75% - 99.94%Forma y color:SolidPeso molecular:232.32PS-1145
CAS:<p>PS-1145 (IKK Inhibitor X) is a specific IKK inhibitor with IC50 of 88 nM.</p>Fórmula:C17H11ClN4OPureza:98.81% - >99.99%Forma y color:SolidPeso molecular:322.75Momordin Ic
CAS:<p>Momordin Ic (Momordin 1c) might represent a potential anticancer activity, by inducing apoptosis through oxidative stress-regulated mitochondrial dysfunction</p>Fórmula:C41H64O13Pureza:98% - 99.69%Forma y color:SolidPeso molecular:764.94Neferine
CAS:<p>Neferine: anti-tumor, enhances DOX efficacy, prevents diabetic vasculopathy; mediates via CYP3A4, GSH depletion, blocks ROS/Akt/NF-κB.</p>Fórmula:C38H44N2O6Pureza:98.81% - 99.65%Forma y color:SolidPeso molecular:624.77Tenovin-3
CAS:Tenovin-3 acts as a p53 activator.Fórmula:C18H21N3OSPureza:99.72% - ≥95%Forma y color:SolidPeso molecular:327.44ELR510444
CAS:<p>ELR510444 (LR510444) is a novel microtubule disruptor; inhibits MDA-MB-231 cell proliferation with IC50 of 30.9 nM.</p>Fórmula:C19H16N2O2S2Pureza:97.67% - 98.69%Forma y color:SolidPeso molecular:368.47PKR-IN-C16
CAS:<p>PKR-IN-C16: inhibits PKR autophosphorylation and translation blockade; binds ATP site; IC50 of 186-210 nM; protects cells from ER stress damage.</p>Fórmula:C13H8N4OSPureza:97.8%Forma y color:SolidPeso molecular:268.29Levomenol
CAS:<p>Levomenol, or (-)-α-Bisabolol, is a sesquiterpene in aromatic plant oils with antioxidant, anti-inflammatory, and anti-apoptotic properties.</p>Fórmula:C15H26OPureza:96.01%Forma y color:Clear To Yellowish LiquidPeso molecular:222.37AG1024
CAS:<p>AG1024 (Tyrphostin) suppresses IGF-1R autophosphorylation(IC50=7 μM), and is less potent for IR(IC50=57 μM).</p>Fórmula:C14H13BrN2OPureza:98% - 99.37%Forma y color:SolidPeso molecular:305.17PIK-75
CAS:<p>PIK-75, a DNA-PK and PI3K inhibitor, suppresses DNA-PK(IC50=2 nM), p110α(IC50=5.8 nM) and p110γ(IC50=76 nM).</p>Fórmula:C16H14BrN5O4SPureza:98.52% - >99.99%Forma y color:SolidPeso molecular:452.28PF-573228
CAS:<p>PF-573228 is an ATP-competitive FAK inhibitor. In a cell-free assay, the IC50 of FAK is 4 nM.</p>Fórmula:C22H20F3N5O3SPureza:96.58% - 99.51%Forma y color:SolidPeso molecular:491.49Thapsigargin
CAS:<p>Thapsigargin is a natural product, an inhibitor of sarcoplasmic/endoplasmic reticulum Ca2+ ATPase (SERCA) and an endoplasmic reticulum stress inducer.</p>Fórmula:C34H50O12Pureza:99.07% - 99.3%Forma y color:Colourless FilmPeso molecular:650.75Laquinimod
CAS:<p>Laquinimod (LAQ) is an effective immunomodulator, which is currently under development in phase III trials for the treatment of multiple sclerosis as an oral</p>Fórmula:C19H17ClN2O3Pureza:98.42% - 98.84%Forma y color:SolidPeso molecular:356.8INCB-057643
CAS:<p>INCB057643 is a potent, selective and orally bioavailable BET inhibitor.</p>Fórmula:C20H21N3O5SPureza:99.5%Forma y color:SolidPeso molecular:415.46Goserelin acetate
CAS:<p>Goserelin acetate (Fertilan) is a synthetic long-acting agonist of gonadotropin-releasing hormone, used in treatments of cancer.</p>Fórmula:C61H88N18O16Pureza:99.77% - >99.99%Forma y color:White Crystalline PowderPeso molecular:1329.46Kumatakenin
CAS:<p>Kumatakenin can suppress >80% of the SOS-inducing activity of Trp-P-1 at <0.06 micromol/mL.</p>Fórmula:C17H14O6Pureza:97.44% - 98.29%Forma y color:SolidPeso molecular:314.29MDK83190
CAS:<p>MDK83190 (Apoptosis Activator 2) is a potent apoptosis activator, induceing caspase-3 activation, PARP cleavage, and DNA fragmentation .</p>Fórmula:C15H9Cl2NO2Pureza:97.40% - 98%Forma y color:Orange SolidPeso molecular:306.14ML162
CAS:ML162 is a covalent glutathione peroxidase 4 (GPX4) inhibitor that induces ferroptosis. ML162 has antitumor activity. Cost-effective and quality-assured.Fórmula:C23H22Cl2N2O3SPureza:98.42% - 99.55%Forma y color:SolidPeso molecular:477.4TPCA-1
CAS:<p>TPCA-1 (TPCA1) is an effective and specific IKK-2 inhibitor (IC50: 17.9 nM); shows >22-fold selectivity over IKK-1 and >550-fold selectivity over others kinases</p>Fórmula:C12H10FN3O2SPureza:95.03% - 97.86%Forma y color:SolidPeso molecular:279.29DAPK Substrate Peptide acetate
<p>DAPK Substrate Peptide acetate is a death-associated protein kinase (DAPK, Km = 9 μM) peptide substrate.</p>Fórmula:C70H115N25O17Pureza:98.12%Forma y color:SolidPeso molecular:1578.82Panobinostat
CAS:<p>Panobinostat (NVP-LBH589) is a broad-spectrum HDAC inhibitor (IC50=5 nM) with oral activity and non-selectivity.</p>Fórmula:C21H23N3O2Pureza:97.2% - 99.81%Forma y color:Yellow SolidPeso molecular:349.43Ketorolac
CAS:<p>Ketorolac (Acuvail) is an NSAID that blocks prostaglandin synthesis, related to heterocyclic acetic acids.</p>Fórmula:C15H13NO3Pureza:99.68%Forma y color:White Crystalline Or White PowderPeso molecular:255.27Epibrassinolide
CAS:<p>Epibrassinolide (BP55) (EBR) is a biologically active compound of the brassinosteroids, is a natural brassinosteroid (BR) derivative, is a plant regulator with</p>Fórmula:C28H48O6Pureza:97.57% - 98.11%Forma y color:SolidPeso molecular:480.68Bortezomib
CAS:<p>Bortezomib (LDP 341) is a 20S proteasome inhibitor (Ki=0.6 nM) that is reversible and selective.</p>Fórmula:C19H25BN4O4Pureza:97.79% - >99.99%Forma y color:Yellow SolidPeso molecular:384.24Ripretinib
CAS:Ripretinib (DCC-2618) is an orally bioavailable inhibitor of KIT and PDGFRA.Fórmula:C24H21BrFN5O2Pureza:99.07% - 99.62%Forma y color:SolidPeso molecular:510.36K858 (Racemic)
CAS:<p>K858 Racemic (K858) is a selective mitotic kinesin Eg5 inhibitor which acts in an ATP-noncompetitive manner.</p>Fórmula:C13H15N3O2SPureza:>99.99%Forma y color:SolidPeso molecular:277.34Polyporenic acid C
CAS:<p>Polyporenic acid C shows inhibitory activity against human collagenase.</p>Fórmula:C31H46O4Pureza:96.84% - 99.71%Forma y color:SolidPeso molecular:482.69[8]-Shogaol
CAS:[8]-Shogaol is a component of ginger and maintains anti-inflammatory activity as a cyclooxygenase-2 inhibitor.Fórmula:C19H28O3Pureza:97.01%Forma y color:SolidPeso molecular:304.42Cobimetinib
CAS:Cobimetinib (GDC-0973) is a MEK1 inhibitor with selective and oral activity. Cobimetinib exhibits antitumor activity. Cost-effective and quality-assured.Fórmula:C21H21F3IN3O2Pureza:98% - 99.61%Forma y color:SolidPeso molecular:531.31FLLL32
CAS:<p>FLLL32 is an effective JAK2/STAT3 inhibitor (IC50 of <5 μM).</p>Fórmula:C28H32O6Pureza:97% - 97.90%Forma y color:SolidPeso molecular:464.55Apremilast
CAS:Apremilast (CC-10004) (CC-10004) is a potent and orally active PDE4 (IC50=74 nM) with anti-inflammation activities.Fórmula:C22H24N2O7SPureza:98.13% - 99.95%Forma y color:SolidPeso molecular:460.50
![[8]-Shogaol](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FT5430.webp&w=3840&q=75)
