Apoptosis
Los inhibidores de la apoptosis son compuestos que previenen o retrasan el proceso de muerte celular programada, conocido como apoptosis. Estos inhibidores son vitales para estudiar los mecanismos de supervivencia celular y se utilizan para investigar enfermedades donde la apoptosis está desregulada, como el cáncer, los trastornos neurodegenerativos y las enfermedades autoinmunes. Al modular la apoptosis, estos inhibidores pueden ayudar en el desarrollo de terapias dirigidas a controlar la muerte celular. En CymitQuimica, ofrecemos una amplia selección de inhibidores de la apoptosis de alta calidad para apoyar su investigación en biología celular, oncología y campos relacionados.
Subcategorías de "Apoptosis"
- ASK(9 productos)
- BCL(11 productos)
- Caspasa(143 productos)
- FOXO1(3 productos)
- IAP(67 productos)
- Mdm2(12 productos)
- PD-1 / PD-L1(139 productos)
- PDK(9 productos)
- PERK(25 productos)
- Serina / treonina quinasa(18 productos)
- Survivin(14 productos)
- TNF(89 productos)
- c-RET(58 productos)
- p53(63 productos)
Mostrar 6 subcategorías más
Se han encontrado 5966 productos de "Apoptosis"
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MAZ51
CAS:MAZ51 is a VEGFR-3 (Flt-4) tyrosine kinase inhibitor.Fórmula:C21H18N2OPureza:98.53%Forma y color:SolidPeso molecular:314.38MPI-0479605
CAS:MPI-0479605 is an ATP competitive and selective inhibitor.Fórmula:C22H29N7OPureza:97.59% - >99.99%Forma y color:SolidPeso molecular:407.51(-)-Alkannin
CAS:<p>(-)-Alkannin (Shikonin) is a natural red naphthoquinone pigment, has antimicrobial, anti-tumor, and anti-inflammatory effects.</p>Fórmula:C16H16O5Pureza:98.18% - 98.8%Forma y color:White Or Slightly Yellow Crystalline Powder SolidPeso molecular:288.3TCS-PIM-1-4a
CAS:<p>SMI-4a, a Pim inhibitor, activates AMPK, halts mTORC1, and kills various myeloid/lymphoid cells (IC50=0.8-40μM).</p>Fórmula:C11H6F3NO2SPureza:99.89%Forma y color:SolidPeso molecular:273.23Dihydrorotenone
CAS:Dihydrorotenone is a potent mitochondrial inhibitor and probably induces Parkinsonian syndrome.Fórmula:C23H24O6Pureza:98.98% - 99.58%Forma y color:SolidPeso molecular:396.43(S)-CPI203
CAS:<p>CPI-203 is an effective BET bromodomain inhibitor (IC50: 37 nM for BRD4).</p>Fórmula:C19H18ClN5OSPureza:99.01% - 99.92%Forma y color:SolidPeso molecular:399.9C646
CAS:<p>C646, a histone acetyltransferase inhibitor, inhibits p300 (Ki: 400 nM, in a cell-free assay).</p>Fórmula:C24H19N3O6Pureza:98% - 99.21%Forma y color:SolidPeso molecular:445.42Methyl protodioscin
CAS:<p>Methyl protodioscin boosts HDL, lowers LDL and triglycerides, has anti-cancer effects, and promotes apoptosis via mitochondrial pathways.</p>Fórmula:C52H86O22Pureza:99.308% - 99.73%Forma y color:SolidPeso molecular:1063.23Scriptaid
CAS:Scriptaid (GCK1026) is an inhibitor of HDAC, and has a greater effect on acetylated H4 than H3.Fórmula:C18H18N2O4Pureza:96.74% - 99.45%Forma y color:SolidPeso molecular:326.35Teneligliptin hydrobromide
CAS:Teneligliptin hydrobromide: potent, novel DPP-4 inhibitor; inhibits human/rat plasma DPP-4 with ~1 nM IC50.Fórmula:C22H30N6OSBrHPureza:97.83% - 99.92%Forma y color:SolidPeso molecular:628.86Aniline mustard
CAS:<p>Aniline mustard (Mesylerythrol) is alkylating mustard with anti-neoplastic activity.</p>Fórmula:C10H13Cl2NPureza:99.54%Forma y color:SolidPeso molecular:218.12Flurbiprofen Axetil
CAS:<p>Flurbiprofen Axetil (Lipfen) is an anti-inflammatory used as an analgesic.</p>Fórmula:C19H19FO4Pureza:97.58% - 98%Forma y color:SolidPeso molecular:330.35Glycitein
CAS:<p>1. Gycitein has weak estrogenic activity. 2. Glycitein (Glycetein) inhibits glioma cell invasion through down-regulation of MMP-3 and MMP-9 gene expression.</p>Fórmula:C16H12O5Pureza:99.23% - 99.94%Forma y color:White PowderPeso molecular:284.269-Methoxycamptothecin
CAS:9-Methoxycamptothecin (MCPT) has antitumour activities through topoisomerase inhibition.Fórmula:C21H18N2O5Pureza:98.49% - 99.56%Forma y color:SolidPeso molecular:378.38Sodium taurodeoxycholate hydrate
CAS:<p>Sodium taurodeoxycholate hydrate (Taurodeoxycholic acid sodium salt monohydrate) has been used in a study to assess the effect of submicellar concentrations of</p>Fórmula:C26H44NO6S·Na·H2OPureza:99.78%Forma y color:SolidPeso molecular:539.7Radotinib
CAS:<p>Radotinib (IY-5511), and sometimes referred to by its investigational name IY5511, is a drug for the treatment of different types of Y, most notably</p>Fórmula:C27H21F3N8OPureza:99.13% - 99.97%Forma y color:SolidPeso molecular:530.5NSC 73150
CAS:<p>6-Methyl-1H-pyrimidin-4-one (NSC 73150) shows antitumor effects, impeding growth in breast, lung, liver cancer, and inducing apoptosis.</p>Fórmula:C12H12N4O2Pureza:99.84%Forma y color:SolidPeso molecular:244.25TAS6417
CAS:Zipalertinib (TAS6417, CLN-081) is a novel, highly potent, orally active covalent EGFR tyrosine kinase inhibitor.Cost-effective and quality-assured.Fórmula:C23H20N6OPureza:99.71%Forma y color:SolidPeso molecular:396.44Ispinesib
CAS:<p>Ispinesib (SB-715992), a selective, effectvie and reversible inhibitor of kinesin spindle protein (KSP), is derived from quinazolinone, with antineoplastic</p>Fórmula:C30H33ClN4O2Pureza:98% - 99.09%Forma y color:SolidPeso molecular:517.06BMS-833923
CAS:<p>BMS-833923 (XL-139), an orally bioavailable Smoothened antagonist, inhibits BODIPY cyclopamine binding to SMO in a dose-dependent manner (IC50: 21 nM).</p>Fórmula:C30H27N5OPureza:99.47% - 99.76%Forma y color:SolidPeso molecular:473.574E1rcat
CAS:<p>4E1RCat is a dual inhibitor of eIF4E:eIF4 g and eIF4E:4E-BP1 interaction. And it inhibits the binding of eIF4 g to eIF4E with IC50 of 3.2 μM.</p>Fórmula:C28H18N2O6Pureza:99.47%Forma y color:SolidPeso molecular:478.45EI1
CAS:EI1 (Ezh2 inhibitor) is a potent and selective EZH2 inhibitor with IC50 of 15 nM and 13 nM for EZH2 (WT) and EZH2 (Y641F), respectively.Fórmula:C23H26N4O2Pureza:99.93%Forma y color:SolidPeso molecular:390.484-MMPB
CAS:15-Lipoxygenase Inhibitor 1 is a selective inhibitor of 15-lipoxygenase, with an IC50 of 18 μM.Fórmula:C16H19N5SPureza:97.18%Forma y color:SolidPeso molecular:313.42pimpinellin
CAS:<p>Pimpinellin is a natural product that acts as antagonist of proteins with GABA receptor activity.</p>Fórmula:C13H10O5Pureza:99.85% - ≥95%Forma y color:SolidPeso molecular:246.22β-Lapachone
CAS:β-Lapachone (ARQ-501) is a specific DNA topoisomerase I inhibitor, and no inhibitory activities against DNA topoisomerase II or ligase.Fórmula:C15H14O3Pureza:99.76% - 99.88%Forma y color:SolidPeso molecular:242.27MX69
CAS:MX69 is the MDM2/XIAP inhibitor, blocking the MDM2 protein-XIAP RNA interaction, leading to MDM2 degradation.Fórmula:C27H26N2O4SPureza:97.27% - 99.57%Forma y color:SolidPeso molecular:474.57Macitentan
CAS:<p>Macitentan (ACT-064992) is an endothelin receptor antagonist that is used in the therapy of pulmonary arterial hypertension (PAH).</p>Fórmula:C19H20Br2N6O4SPureza:98% - >99.99%Forma y color:SolidPeso molecular:588.27DAPT
CAS:<p>DAPT (LY-374973) is a γ-secretase inhibitor that inhibits total Aβ and Aβ42 (IC50=115/200 nM) and is orally active.</p>Fórmula:C23H26F2N2O4Pureza:98.06% - 99.81%Forma y color:White SolidPeso molecular:432.46Isatin
CAS:<p>Isatin (2,3-Indolinedione) is an endogenous MAO inhibitor.</p>Fórmula:C8H5NO2Pureza:98.92%Forma y color:Yellow To Reddish Crystalline SolidPeso molecular:147.13Bay 11-7085
CAS:<p>Bay 11-7085 can irreversibly inhibit the IκBα phosphorylation induced by TNFα (IC50: 10 μM).</p>Fórmula:C13H15NO2SPureza:99.76% - 99.94%Forma y color:White SolidPeso molecular:249.33BDA-366
CAS:BDA-366, a potent Bcl2 antagonist, selectively binds the Bcl2-BH4 domain with high affinity (Ki = 3.3 nM), inducing a conformational change that nullifies itsFórmula:C24H29N3O4Pureza:98.61%Forma y color:SoildPeso molecular:423.53BDO
CAS:3BDO is a new mTOR activator. 3BDO inhibits autophagy.Fórmula:C18H17NO5Pureza:97.76%Forma y color:SolidPeso molecular:327.33UNC1215
CAS:<p>UNC1215, a potent MBT antagonist, targets L3MBTL3 with high selectivity (IC50: 40 nM, Kd: 120 nM, 50x versus MBT family).</p>Fórmula:C32H43N5O2Pureza:98% - 99.04%Forma y color:SolidPeso molecular:529.72H-Gly-Arg-Gly-Asp-Asn-Pro-OH
CAS:RGD peptide (GRGDNP) (RGD peptide GRGDNP(2TFA)) is a integrin-ligand interactions inhibitor.Fórmula:C23H38N10O10Pureza:>99.99%Forma y color:SolidPeso molecular:614.61Sodium dichloroacetate
CAS:Sodium dichloroacetate (BCA) inhibits PDK (IC50: 183 μM PDK2, 80 μM PDK4), triggers cancer cell apoptosis, and impedes tumor growth.Fórmula:C2HCl2NaO2Pureza:99.32% - 99.87%Forma y color:White PowderPeso molecular:150.92AES-350
CAS:AES-350, an HDAC6 inhibitor (IC50: 0.0244 μM), also targets HDAC-3, -8, -11, induces AML cell apoptosis, and aids AML research.Fórmula:C18H20N2O3Pureza:98.82%Forma y color:SolidPeso molecular:312.36N-Formyl-Met-Leu-Phe
CAS:<p>N-Formyl-Met-Leu-Phe (N-Formyl-MLF) (fMLF) is a synthetic peptide that acts as an agonist at formyl peptide receptors (FPR; Ki = 0.8 pM).</p>Fórmula:C21H31N3O5SPureza:98.69% - ≥95%Forma y color:SolidPeso molecular:437.55Rotundic acid
CAS:Rotundic acid fights various cancers: HepG2, A375, NCI-H446, MCF-7, and HT-29.Fórmula:C30H48O5Pureza:96.91% - 99.97%Forma y color:SolidPeso molecular:488.70Medicarpin
CAS:<p>Medicarpin, an ER agonist, stimulates osteoblasts, enhances peak bone mass, has no uterine effects, and is orally bioavailable.</p>Fórmula:C16H14O4Pureza:99.32% - 99.86%Forma y color:SolidPeso molecular:270.28Isobavachalcone
CAS:<p>Isobavachalcone (Corylifolinin) is a chalcone constituent of Angelica keiskei, has potent anti-inflammatory activity, possible can ameliorate neuronal injury in</p>Fórmula:C20H20O4Pureza:98% - 99.76%Forma y color:SolidPeso molecular:324.37Apremilast
CAS:Apremilast (CC-10004) (CC-10004) is a potent and orally active PDE4 (IC50=74 nM) with anti-inflammation activities.Fórmula:C22H24N2O7SPureza:98.13% - 99.95%Forma y color:SolidPeso molecular:460.50FLLL32
CAS:<p>FLLL32 is an effective JAK2/STAT3 inhibitor (IC50 of <5 μM).</p>Fórmula:C28H32O6Pureza:97% - 97.90%Forma y color:SolidPeso molecular:464.55Palmatine chloride
CAS:Palmatine chloride an isoquinoline alkaloid, is an important medicinal herbal extract with diverse pharmacological and biological properties.Fórmula:C21H22ClNO4Pureza:97.9% - 99.47%Forma y color:SolidPeso molecular:387.86Polyporenic acid C
CAS:Polyporenic acid C shows inhibitory activity against human collagenase.Fórmula:C31H46O4Pureza:96.84% - 99.90%Forma y color:SolidPeso molecular:482.69RITA
CAS:<p>RITA (NSC-652287) forms DNA-DNA/protein cross-links without DNA breaks; disrupts p53/Mdm2 like nutlin-3.</p>Fórmula:C14H12O3S2Pureza:98.49% - 99.55%Forma y color:SolidPeso molecular:292.37Bortezomib
CAS:Bortezomib (LDP 341) is a 20S proteasome inhibitor (Ki=0.6 nM) that is reversible and selective.Fórmula:C19H25BN4O4Pureza:97.79% - >99.99%Forma y color:Yellow SolidPeso molecular:384.24Danshensu
CAS:<p>Danshensu (Dan shen suan A) is an active ingredient of Salvia miltiorrhiza with wide cardiovascular benefit.</p>Fórmula:C9H10O5Pureza:98.4% - 99.74%Forma y color:SolidPeso molecular:198.17IACS-010759
CAS:IACS-010759 is an orally bioavailable inhibitor of complex I of oxidative phosphorylation of the mitochondrial electron transport chain.Fórmula:C25H25F3N6O4SPureza:99.54% - 99.73%Forma y color:SolidPeso molecular:562.56Ketorolac
CAS:Ketorolac (Acuvail) is an NSAID that blocks prostaglandin synthesis, related to heterocyclic acetic acids.Fórmula:C15H13NO3Pureza:99.68%Forma y color:White Crystalline Or White PowderPeso molecular:255.27TPCA-1
CAS:<p>TPCA-1 (TPCA1) is an effective and specific IKK-2 inhibitor (IC50: 17.9 nM); shows >22-fold selectivity over IKK-1 and >550-fold selectivity over others kinases</p>Fórmula:C12H10FN3O2SPureza:95.03% - 97.86%Forma y color:SolidPeso molecular:279.29
