Apoptosis
Los inhibidores de la apoptosis son compuestos que previenen o retrasan el proceso de muerte celular programada, conocido como apoptosis. Estos inhibidores son vitales para estudiar los mecanismos de supervivencia celular y se utilizan para investigar enfermedades donde la apoptosis está desregulada, como el cáncer, los trastornos neurodegenerativos y las enfermedades autoinmunes. Al modular la apoptosis, estos inhibidores pueden ayudar en el desarrollo de terapias dirigidas a controlar la muerte celular. En CymitQuimica, ofrecemos una amplia selección de inhibidores de la apoptosis de alta calidad para apoyar su investigación en biología celular, oncología y campos relacionados.
Subcategorías de "Apoptosis"
- ASK(9 productos)
- BCL(8 productos)
- Caspasa(147 productos)
- FOXO1(3 productos)
- IAP(67 productos)
- Mdm2(12 productos)
- PD-1 / PD-L1(140 productos)
- PDK(9 productos)
- PERK(26 productos)
- Serina / treonina quinasa(19 productos)
- Survivin(14 productos)
- TNF(91 productos)
- c-RET(61 productos)
- p53(63 productos)
Mostrar 6 subcategorías más
Se han encontrado 6114 productos de "Apoptosis"
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Trametinib (DMSO solvate)
CAS:Trametinib (DMSO solvate) (GSK-1120212 (DMSO solvate)) is a Highly Potent and Selective MEK Inhibitor that specifically inhibits MEK1/2(IC50 :2 nM)Fórmula:C28H29FIN5O5SPureza:99.71% - 99.92%Forma y color:SolidPeso molecular:693.53TCS PrP Inhibitor 13
CAS:TCS PrP Inhibitor 13 (5-(4-Nitrophenyl)-2-Phenyl-4H-Pyrazol-3-One) is an antiprion agent inhibiting protease-resistant prion protein (PrP-res) accumulation.Fórmula:C15H11N3O3Pureza:99.7%Forma y color:SolidPeso molecular:281.27Ref: TM-T23450
5mg35,00€10mg55,00€25mg100,00€50mg156,00€100mg231,00€200mg329,00€1mL*10mM (DMSO)38,00€Cladribine
CAS:Cladribine (2CdA), an adenosine deaminase inhibitor, is utilized in the treatment of lymphoproliferative diseases.Fórmula:C10H12ClN5O3Pureza:99.58% - >99.99%Forma y color:White Crystalline SolidPeso molecular:285.69Talampanel
CAS:Talampanel (LY-300164), an oral selective AMPA receptor antagonist, exhibits anti-seizure and neuroprotective properties.Fórmula:C19H19N3O3Pureza:98.3%Forma y color:SolidPeso molecular:337.37ENMD-1068 hydrochloride
CAS:ENMD-1068 hydrochloride: selective PAR2 antagonist, counters liver fibrosis, hinders endometrial cell growth, and induces apoptosis in studies.Fórmula:C15H30ClN3O2Forma y color:SolidPeso molecular:319.87Glycochenodeoxycholic acid sodium salt
CAS:GCDCA, a bile acid-glycine salt, is a secondary bile acid from colonic microbes.Fórmula:C26H42NNaO5Pureza:95.48% - 99.82%Forma y color:SolidPeso molecular:471.61σ1 Receptor antagonist-1
CAS:σ1 Receptor antagonist-1 is a selective sigma 1 receptor antagonist.Fórmula:C21H23NOSPureza:99.8%Forma y color:SolidPeso molecular:337.48Tenovin-6 Hydrochloride
CAS:Tenovin-6 HCl: Inhibits SIRT1 (21µM), SIRT2 (10µM), HDAC8; potent p53 activator.Fórmula:C25H35ClN4O2SPureza:99.36%Forma y color:SolidPeso molecular:491.09Ref: TM-T8480
1mg39,00€2mg51,00€5mg70,00€10mg88,00€25mg140,00€50mg226,00€100mg376,00€1mL*10mM (DMSO)73,00€Azoramide
CAS:Azoramide, a small-molecule modulator, has the antidiabetic activity of unfolded protein response.Fórmula:C15H17ClN2OSPureza:99.08% - 99.85%Forma y color:SolidPeso molecular:308.83Thalidomide-5-methyl
CAS:Thalidomide-5-methyl is the Thalidomide-based cereblon (CRBN) ligand. Thalidomide-5-methyl is used in the recruitment of CRBN protein.Fórmula:C14H12N2O4Pureza:99.48%Forma y color:SolidPeso molecular:272.26Ref: TM-T40503
1mg65,00€5mg144,00€10mg210,00€25mg359,00€50mg504,00€100mg680,00€200mg919,00€1mL*10mM (DMSO)130,00€Laquinimod
CAS:Laquinimod (LAQ) is an effective immunomodulator, which is currently under development in phase III trials for the treatment of multiple sclerosis as an oral
Fórmula:C19H17ClN2O3Pureza:98.42% - 98.84%Forma y color:SolidPeso molecular:356.8Tenovin-3
CAS:Tenovin-3 acts as a p53 activator.Fórmula:C18H21N3OSPureza:99.72% - ≥95%Forma y color:SolidPeso molecular:327.44PKD-IN-1 dihydrochloride (956121-30-5 free base)
CAS:CRT0066101 dihydrochloride is an inhibitor of PKD.Fórmula:C18H21Cl3N4OPureza:99.5%Forma y color:SolidPeso molecular:415.75PEAQX
CAS:PEAQX (NVP-AAM077) is an oral NMDA antagonist, inhibits 1A/2A receptors (IC50: 270 nM), less so 1A/2B (IC50: 29,600 nM).Fórmula:C17H17BrN3O5PPureza:98% - 99.9%Forma y color:SolidPeso molecular:454.21Ref: TM-T4171
1mg34,00€2mg46,00€5mg74,00€10mg125,00€25mg216,00€50mg338,00€100mg470,00€200mg680,00€1mL*10mM (DMSO)97,00€Bilobalide
CAS:Bilobalide ((-)-Bilobalide), a bioactive from Gingko Biloba, is active on hypoxia-induced alterations.Fórmula:C15H18O8Pureza:98.81% - 99.92%Forma y color:White SolidPeso molecular:326.30Ipatasertib
CAS:Ipatasertib (GDC-0068) is a selective, ATP-competitive pan-Akt inhibitor that can lead to p53-independent PUMA activation.Cost-effective and quality-assured.Fórmula:C24H32ClN5O2Pureza:98.28% - 99.79%Forma y color:SolidPeso molecular:458Nω-Hydroxy-nor-L-Arginine Dihydrochloride
CAS:Nω-Hydroxy-nor-L-Arginine Dihydrochloride is a competitive and reversible inhibitor of arginaseFórmula:C5H14Cl2N4O3Pureza:99.12% - 99.84%Forma y color:SolidPeso molecular:249.10Ref: TM-T9096
1mg38,00€2mg50,00€5mg84,00€10mg116,00€25mg225,00€50mg335,00€100mg469,00€500mgA consultarAlda-1
CAS:Alda-1 activates ALDH2*1 and ALDH2*2, permeates cells, and targets mitochondrial aldehyde dehydrogenase 2.Fórmula:C15H11Cl2NO3Pureza:98.5% - 99.63%Forma y color:SolidPeso molecular:324.16Ref: TM-T2662
5mg42,00€10mg62,00€25mg78,00€50mg87,00€100mg156,00€200mg195,00€500mg442,00€1mL*10mM (DMSO)67,00€Eltrombopag Olamine
CAS:Eltrombopag Olamine (Eltrombopag diethanolamine salt) is the orally active ethanolamine salt of eltrombopag, a small-molecule, nonpeptide thrombopoietinFórmula:C29H36N6O6Pureza:99.59% - 99.89%Forma y color:SolidPeso molecular:564.63Ref: TM-T6825
2mg43,00€5mg64,00€10mg90,00€25mg140,00€50mg177,00€100mg230,00€200mg340,00€500mg563,00€1mL*10mM (DMSO)90,00€HA15
CAS:HA15 targets BiP/GRP78/HSPA5, showing anti-cancer effects on all tested melanoma cells, resistant or patient-derived.Fórmula:C23H22N4O3S2Pureza:99.77% - 99.86%Forma y color:SolidPeso molecular:466.58Ref: TM-T6855
1mg35,00€2mg48,00€5mg72,00€10mg96,00€25mg187,00€50mg283,00€100mg439,00€1mL*10mM (DMSO)74,00€ISRIB (trans-isomer)
CAS:ISRIB (trans-isomer) is a potent inhibitor of PERK that rescues protein translation and prevents SG formation in the presence of P-eIF2α. Cost effective and quality assured.Fórmula:C22H24Cl2N2O4Pureza:97.86% - 99.27%Forma y color:SolidPeso molecular:451.34CA-4948
CAS:CA-4948 (Emavusertib) is a potent IRAK4/FLT3 inhibtor. CA-4948 with anti-tumor activity.Fórmula:C24H25N7O5Pureza:99.35% - 99.88%Forma y color:SolidPeso molecular:491.5Ref: TM-T9027
1mg35,00€2mg52,00€5mg77,00€10mg87,00€25mg170,00€50mg311,00€100mg535,00€1mL*10mM (DMSO)84,00€Tenovin-6
CAS:Tenovin-6 is a p53 transcriptional activity agonist.Fórmula:C25H34N4O2SPureza:98.89% - >99.99%Forma y color:SolidPeso molecular:454.63Ref: TM-T1818
1mg43,00€2mg56,00€5mg77,00€10mg87,00€25mg157,00€50mg230,00€100mg393,00€500mg930,00€1mL*10mM (DMSO)79,00€Dacarbazine citrate
CAS:Dacarbazine citrate treats lymphatic cancers, malignant melanoma, islet cell carcinoma, and soft tissue sarcoma.Fórmula:C12H18N6O8Forma y color:SolidPeso molecular:374.31FOXO4-DRI acetate
FOXO4-DRI acetate is a bioactive chemical.Fórmula:C36H64N14O14SPureza:99.10%Forma y color:SolidPeso molecular:5358.06TrxR1-IN-B19
CAS:TrxR1-IN-B19 (TrxR1 IN B19), a TrxR1 inhibitor, selectively kills gastric cancer cells by a small molecule via targeting TrxR1 and ROS-mediated ER stressFórmula:C21H22O5Pureza:98.6%Forma y color:SolidPeso molecular:354.4Ref: TM-T29017
1mg96,00€2mg115,00€5mg170,00€10mg270,00€25mg444,00€50mg620,00€100mg837,00€200mg1.121,00€1mL*10mM (DMSO)178,00€Thalidomide-O-amido-C3-NH2 TFA
CAS:Thalidomide-based E3 ligase linker for PROTAC tech; cereblon ligand conjugate.Fórmula:C20H21F3N4O8Pureza:98.47%Forma y color:SolidPeso molecular:502.4Methoxychlor
CAS:Methoxychlor, an organochlorine pesticide, is thought to be an endocrine disrupter that affects Ca2 homeostasis and cell viability in different cell models.Fórmula:C16H15Cl3O2Pureza:98.82% - ≥95%Forma y color:Colorless Crystals (Technical Grey Powder) To The Environment Immediate Steps Should Be Taken To Limit Its Spread To The Environment IfPeso molecular:345.65Liproxstatin-1 hydrochloride
CAS:Liproxstatin-1 hydrochloride is a high-potency ferroptosis inhibitor capable of effectively preventing ferroptotic cell death, with an IC50 value of 22 nM [1].Fórmula:C19H22Cl2N4Forma y color:SolidPeso molecular:377.31Thalidomide-4-OH
CAS:Thalidomide-4-OH, a Thalidomide-derived Cereblon binder, recruits CRBN and serves as a PROTAC linker.Fórmula:C13H10N2O5Pureza:99.59%Forma y color:SolidPeso molecular:274.23Difurazon hydrochloride
CAS:Difurazon HCl: a mutagenic antibacterial and growth promoter, used for bacillary dysentery in feed.Fórmula:C14H13ClN6O6Pureza:98.51%Forma y color:SolidPeso molecular:396.74Bigelovin
CAS:Bigelovin: RXRα agonist, inhibits mTOR via ROS, induces apoptosis/autophagy, anti-tumor sesquiterpene from Inula sp.Fórmula:C17H20O5Pureza:99.61% - 99.72%Forma y color:SolidPeso molecular:304.34Ref: TM-TN6735
1mg96,00€5mg205,00€10mg268,00€25mg465,00€50mg662,00€100mg888,00€1mL*10mM (DMSO)203,00€KRCA-0008
CAS:KRCA-0008 is an effective and specific ALK/Ack1 inhibitor (IC50: 12/4 nM); displays drug-like properties without hERG liability.Fórmula:C30H37ClN8O4Pureza:96.19%Forma y color:SolidPeso molecular:609.12Perhexiline
CAS:Perhexiline: oral CPT1/2 inhibitor, limits fat metabolism, crosses BBB, anti-cancer, induces liver cell apoptosis, for cancer/cardio research.Fórmula:C19H35NForma y color:SolidPeso molecular:277.49Ketorolac hemicalcium
CAS:Ketorolac hemicalcium: NSAID, COX-1/COX-2 inhibitor (IC50: 20/120 nM), treats eye inflammation & pain, used in cancer research.Fórmula:C30H24CaN2O6Forma y color:SolidPeso molecular:548.608Thalidomide-NH-C6-NH2 hydrochloride
CAS:Pomalidomide-C6-NH2 HCl is a synthetic conjugate for PROTAC, combining CRBN ligand and linker.
Fórmula:C19H25ClN4O4Pureza:99.27%Forma y color:SolidPeso molecular:408.88Verteporfin
CAS:Verteporfin (BPD-MA) is a YAP inhibitor that inhibits YAP-TEAD interactions.Fórmula:C41H42N4O8Pureza:95.37% - 99.82%Forma y color:Dark Green To Black SolidPeso molecular:718.79Ref: TM-T3112
1mg40,00€2mg51,00€5mg85,00€10mg115,00€25mg225,00€50mg365,00€100mg462,00€1mL*10mM (DMSO)120,00€Sulfaphenazole
CAS:Sulfaphenazole (Plisulfan) is an inhibitor of CYP2C9 (Ki: 0.3 μM) that demonstrates at least 100-fold selectivity over other CYP450 isoforms (Ki: 63/29 μM for
Fórmula:C15H14N4O2SPureza:97.53% - 99.67%Forma y color:SolidPeso molecular:314.36PK11000
CAS:PK11000 is a p53 targeting compound, has anti-tumor activities through activation of unstable p53.Fórmula:C6H5ClN2O4SPureza:99.70%Forma y color:SolidPeso molecular:236.63Abacavir monosulfate
CAS:Abacavir monosulfate: oral HIV inhibitor, anticancer; crosses blood-brain barrier, suppresses telomerase.Fórmula:C14H20N6O5SForma y color:SolidPeso molecular:384.41Thalidomide-O-amido-PEG2-C2-NH2 TFA
CAS:Thalidomide-based E3 ligase ligand-linker for PROTAC with PEG2 bridge; cereblon-targeted.
Fórmula:C23H27F3N4O10Pureza:95.74% - 99%Forma y color:SolidPeso molecular:576.48KX2-361
CAS:KX2-361 is a orally bioavailable small molecule dual Src/tubulin inhibitor that provides long term survival in a murine model of glioblastomaFórmula:C24H24FN3O2Pureza:99.64% - 99.68%Forma y color:SolidPeso molecular:405.46Ref: TM-T9411
1mg81,00€5mg170,00€10mg235,00€25mg386,00€50mg543,00€100mg730,00€200mg938,00€1mL*10mM (DMSO)182,00€Ralimetinib dimesylate
CAS:Ralimetinib dimesylate (LY2228820 dimesylate) is a orally available, p38 MAPK inhibitor with potential anti-inflammatory and antineoplastic activities.Fórmula:C24H29FN6·2CH4O3SPureza:98% - 99.38%Forma y color:SolidPeso molecular:612.74Crebanine
CAS:Crebanine mitigates arrhythmias, increases aconitine tolerance in rats, lacks effect on ouabain-induce arrhythmias, and shows anti-cancer properties.Fórmula:C20H21NO4Pureza:99.17% - 99.77%Forma y color:SolidPeso molecular:339.39DEL-22379
CAS:DEL-22379 is a water-soluble ERK dimerization inhibitor with IC50 of ～0.5 μM.Fórmula:C26H28N4O3Pureza:99.3% - 99.53%Forma y color:SolidPeso molecular:444.53Rabeprazole sodium
CAS:Rabeprazole sodium treats stomach ulcers and Zollinger-Ellison syndrome, blocking ATPase in gastric cells.Fórmula:C18H20N3NaO3SPureza:98% - 99.912%Forma y color:White Or Off White Crystalline PowderPeso molecular:381.42Mitochonic acid 5
CAS:MA-5, derived from a plant hormone, binds mitochondria and reduces heart/kidney damage, aiding mitochondrial disease survival.Fórmula:C18H13F2NO3Pureza:98.85%Forma y color:SolidPeso molecular:329.3Avadomide HCl
CAS:Avadomide (CC-122), an oral drug, targets CRBN, degrades Ikaros/Aiolos, and mimics interferon, showing antitumor effects in DLBCL.Fórmula:C14H15ClN4O3Forma y color:SolidPeso molecular:322.75NAE-IN-M22
CAS:NAE-IN-M22: Selective, potent NEDD8 enzyme inhibitor; blocks cancer cell growth; induces apoptosis in A549 cells; effective in vivo.Fórmula:C20H24Cl2N2Pureza:97.65%Forma y color:SolidPeso molecular:363.32Ref: TM-T8816
1mg92,00€5mg216,00€10mg323,00€25mg547,00€50mg783,00€100mg1.074,00€500mg2.175,00€1mL*10mM (DMSO)240,00€Lercanidipine hydrochloride
CAS:Lercanidipine hydrochloride (Corifeo) is a calcium channel blocker of the dihydropyridine class.Fórmula:C36H41N3O6·HClPureza:99.86% - 99.91%Forma y color:Pale-Yellow PowderPeso molecular:648.19
