Apoptosis
Los inhibidores de la apoptosis son compuestos que previenen o retrasan el proceso de muerte celular programada, conocido como apoptosis. Estos inhibidores son vitales para estudiar los mecanismos de supervivencia celular y se utilizan para investigar enfermedades donde la apoptosis está desregulada, como el cáncer, los trastornos neurodegenerativos y las enfermedades autoinmunes. Al modular la apoptosis, estos inhibidores pueden ayudar en el desarrollo de terapias dirigidas a controlar la muerte celular. En CymitQuimica, ofrecemos una amplia selección de inhibidores de la apoptosis de alta calidad para apoyar su investigación en biología celular, oncología y campos relacionados.
Subcategorías de "Apoptosis"
- ASK(9 productos)
- BCL(8 productos)
- Caspasa(147 productos)
- FOXO1(3 productos)
- IAP(67 productos)
- Mdm2(12 productos)
- PD-1 / PD-L1(140 productos)
- PDK(9 productos)
- PERK(26 productos)
- Serina / treonina quinasa(19 productos)
- Survivin(14 productos)
- TNF(91 productos)
- c-RET(61 productos)
- p53(63 productos)
Mostrar 6 subcategorías más
Se han encontrado 6114 productos de "Apoptosis"
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CAS:SEC triggers ANXA7 GTPase via AMPK/mTORC1/STAT3, causing ITGB4-driven apoptosis in ITGB4-high cancer cells.Fórmula:C22H23ClN2O5Forma y color:SolidPeso molecular:430.88RET-IN-16
CAS:RET-IN-16: Selective RET inhibitor, IC50s 3.98-15.05 nM for various RET mutations; anticancer properties.Fórmula:C31H29F3N8O2Forma y color:SolidPeso molecular:602.61c-Fms-IN-12
CAS:c-Fms-IN-12 inhibits FMS/c-KIT, triggers A549 cell apoptosis, and has potential as a multi-cancer therapy.Fórmula:C30H32N6O6Forma y color:SolidPeso molecular:572.61PD-1/PD-L1-IN 5
CAS:PD-1/PD-L1-IN 5 is a potent PD-1/PD-L1 protein/protein interaction inhibitor (IC50 ≤ 100 nM).Fórmula:C22H18N4O3SForma y color:SolidPeso molecular:418.47Oxythiamine chloride HCl
CAS:Oxythiamine chloride is a thiamine antagonist and anticancer agent that inhibits transketolase, affecting RNA/DNA synthesis and inducing apoptosis.Fórmula:C12H17Cl2N3O2SForma y color:SolidPeso molecular:338.25IQDMA
CAS:IQDMA is an inhibitor of the transcription factor STAT5.Fórmula:C19H20N4Forma y color:SolidPeso molecular:304.39NBI-42902
CAS:NBI-42902 is a potent GnRH receptor antagonist (Ki=0.56 nm, Kd=0.19 nm), suppressing serum LH in macaques without causing histamine release.Fórmula:C27H24F3N3O3Forma y color:SolidPeso molecular:495.49Theophylline sodium glycinate
CAS:Theophylline sodium glycinate inhibits PDE3, treats asthma/COPD, blocks adenosine receptors, activates HDAC, reduces inflammation and induces apoptosis.Fórmula:C9H12N5NaO4Forma y color:SolidPeso molecular:277.216SZM-1209
CAS:SZM-1209 is a potent and specific RIPK1 inhibitor with oral activity, displaying a dissociation constant (Kd) of 85 nM.Fórmula:C31H29F5N4O5S2Pureza:98%Forma y color:SolidPeso molecular:696.71Anticancer agent 50
CAS:Anticancer agent 50 targets ABCB1 pump, has cytotoxic effects, alters cyclin D1/p53, and shows promise in T lymphoma research.Fórmula:C30H32N2O4SeForma y color:SolidPeso molecular:563.55YC-137
CAS:YC-137 inhibits BCL-2, triggers apoptosis in Bcl-2-high cells, and blocks its anti-apoptotic function.Fórmula:C24H21N3O6S2Forma y color:SolidPeso molecular:511.57PI3Kδ/γ-IN-3
CAS:PI3Kδ/γ-IN-3 (Compound 58) is an orally active dual inhibitor of PI3Kδ (IC50: 1 nM) and PI3Kγ (IC50: 16 nM).Fórmula:C23H20ClN9OForma y color:SolidPeso molecular:473.92Justicidin B
CAS:Justicidin B: anticancer, proapoptotic, inhibits bone resorption & platelets, antiviral, fungicidal, antiprotozoal.Fórmula:C21H16O6Forma y color:SolidPeso molecular:364.35Isodispar B
CAS:Isodispar B: an anticancer drug, halts many cancer types' growth, triggers cell death.Fórmula:C20H18O5Forma y color:SolidPeso molecular:338.35STAT3-IN-10
CAS:STAT3-IN-10 (A11) inhibits STAT3; halts tumor growth and triggers apoptosis in cancer cells (IC 50 = 5.18 μM).Fórmula:C17H13NO5Forma y color:SolidPeso molecular:311.29Bcl-2-IN-9
CAS:Bcl-2-IN-9: a novel, selective Bcl-2 inhibitor inducing apoptosis in leukemia with an IC50 of 2.9 μM; low cytotoxicity.Fórmula:C27H31N7O3SForma y color:SolidPeso molecular:533.65Anticancer agent 58
Anticancer agent 58 targets A549/T24 cell lines; IC50: 0.6/0.7 μM. It triggers apoptosis, ups Ca2+/ROS, and lowers mitochondrial potential.Fórmula:C39H55NO5Forma y color:SolidPeso molecular:617.86EGFR/BRAFV600E-IN-1
CAS:EGFR/BRAFV600E-IN-1 inhibits EGFR (0.08 μM) & BRAFV600E (0.15 μM), affects A-549, MCF-7, Panc-1 & HT-29 (IC50: 0.79-1.3 μM).Fórmula:C24H24ClN3O3Forma y color:SolidPeso molecular:437.92MDM2/XIAP-IN-3
CAS:MDM2/XIAP-IN-3 (compound 3e), a dual inhibitor of MDM2/XIAP, diminishes MDM2 and XIAP protein levels while augmenting p53 expression, consequently suppressingFórmula:C29H30N2O5SForma y color:SolidPeso molecular:518.62DNA topoisomerase II inhibitor 1
CAS:Potent DNA topoisomerase II blocker; arrests cell cycle, induces apoptosis, anti-growth effects.Fórmula:C28H24N4O3SForma y color:SolidPeso molecular:496.58CS1
CAS:CS1: potent topoisomerase II alpha inhibitor, broad-spectrum antitumor, low toxicity, anti-resistance, induces DNA damage, G2/M arrest, apoptosis.Fórmula:C16H12O3Forma y color:SolidPeso molecular:252.26Vin-F03
CAS:Vin-F03 protects pancreatic β-cells in type 2 diabetes research with an EC50 of 0.27 μM and prevents STZ-induced apoptosis.Fórmula:C22H29N3Forma y color:SolidPeso molecular:335.49CA224
CAS:CA224: selective oral Cdk4-cyclin D1 inhibitor, IC50=6.2μM, promotes apoptosis, has antitumor effects.Fórmula:C24H22N2OForma y color:SolidPeso molecular:354.44Antitumor agent-55
CAS:Antitumor agent-55 (5q) inhibits PC3 (IC50: 0.91 μM), blocks G1/S phase, induces apoptosis, and halts migration.Fórmula:C32H34N6O4SForma y color:SolidPeso molecular:598.72(rel)-Oxaliplatin
CAS:(rel)-Oxaliplatin, a DNA inhibitor, induces crosslinks, hinders replication/transcription, and triggers apoptosis; used in cancer studies.Fórmula:C8H14N2O4PtForma y color:SolidPeso molecular:397.29YM-155 hydrochloride
CAS:Sepantronium hydrochloride (YM-155 hydrochloride) is a novel survivin suppressant that inhibits survivin promoter with an IC 50 of 0.54 nM[1].Fórmula:C20H19ClN4O3Forma y color:SolidPeso molecular:398.85PI3K-IN-34
CAS:PI3K-IN-34 targets PI3K-α/β/δ (IC50: 11.73/6.09/11.18 μM); potential leukemia research tool.Fórmula:C23H22N6O3Forma y color:SolidPeso molecular:430.46PI3K/Akt/mTOR-IN-2
CAS:Potent PI3K/AKT/mTOR inhibitor, selective for MDA-MB-231 cells with IC50 of 2.29 μM; induces arrest and apoptosis.Fórmula:C17H13F2NOPureza:99.98%Forma y color:SolidPeso molecular:285.29Ref: TM-T60564
1mg39,00€5mg84,00€10mg131,00€25mg269,00€50mg432,00€100mg635,00€500mg1.349,00€1mL*10mM (DMSO)92,00€Anti-inflammatory agent 55
CAS:Compound 9j (anti-inflammatory agent 55), a Coixol derivative, exhibits anti-inflammatory properties by inhibiting the NF-κB pathway and reducing the expressionFórmula:C17H15N3O7Forma y color:SolidPeso molecular:373.32Esuberaprost Sodium
CAS:Famitinib (SHR1020), an oral drug, inhibits c-kit, VEGFR-2, and PDGFRβ (IC50: 2.3/4.7/6.6 nM) and triggers apoptosis in gastric cancer.
Fórmula:C23H27FN4O2Forma y color:SolidPeso molecular:410.48hGGPPS-IN-1
CAS:HGGPPS-IN-1: analog of C2-ThP-BPs, inhibits hGGPPS, triggers apoptosis in MM cells, shows anti-myeloma effects in vivo.Fórmula:C13H13N3O6P2SForma y color:SolidPeso molecular:401.27Anti-inflammatory agent 15
CAS:Compound 29, anti-inflammatory and antimycobacterial, halts Mtb H37Rv and M299 growth; MIC50 at 2.3 and 7.8 μM. Blocks iNOS, TNF-α, IL-1β.Fórmula:C17H20N2SForma y color:SolidPeso molecular:284.42PDMP (hydrochloride)
CAS:PDMP, a glucosylceramide synthase inhibitor with 4 stereoisomers, acts at 0.8μM; D-threo enantiomer also blocks lactosylceramide synthesis.Fórmula:C23H39ClN2O3Forma y color:SolidPeso molecular:427.03IW-927
CAS:IW-927 is a potent and selective TNFα/TNFRc1 interaction antagonist.Fórmula:C22H23N3O3S2Forma y color:SolidPeso molecular:441.57Apoptosis inducer 8
CAS:Apoptosis inducer 8 is a galectin-1 (gal-1)-mediated apoptosis inducer and a PET imaging agent that significantly reduces gal-1 protein levels and can be usedFórmula:C29H22ClN5O2Forma y color:SolidPeso molecular:507.97Mps1-IN-5
CAS:Mps1-IN-5: oral Mps1 inhibitor with 29 nM IC50, induces apoptosis, G2/M arrest, and has anti-tumor properties.Fórmula:C24H25N9Forma y color:SolidPeso molecular:439.52GY1-22
CAS:GY1-22, an inhibitor targeting the DNAJA1-mutP53 R175H interaction pocket, holds potential for cancer research applications.Fórmula:C23H20N4OSForma y color:SolidPeso molecular:400.5GK563
CAS:GK563, an iPLA2 inhibitor (IC50=1nM), is 22,000x more potent vs. cPLA2 and may reduce β-cell death in type 1 diabetes.Fórmula:C16H22O2Forma y color:SolidPeso molecular:246.34MeOIstPyrd
CAS:MeOIstPyrd is an anti-skin cancer agent that inhibits cell proliferation, migration, and spheroid formation through activation of the mitochondrial intrinsicFórmula:C14H16N4O2SForma y color:SolidPeso molecular:304.37KRC-108
CAS:KRC-108 is a potent kinase inhibitor targeting Ron, Flt3, TrkA, and c-Met with strong anti-proliferative effects on various cancer cells.Fórmula:C20H20N6OForma y color:SolidPeso molecular:360.41hnRNPK-IN-1
CAS:hnRNPK-IN-1 binds hnRNPK tightly (Kd 4.6-2.6 μM), disrupting c-myc transcription and inducing apoptosis in Hela cells.Fórmula:C23H21N3O5Forma y color:SolidPeso molecular:419.43MDM2/XIAP-IN-2
CAS:MDM2/XIAP-IN-2 is a dual inhibitor targeting murine double minute 2 (MDM2) and X-linked inhibitor of apoptosis protein (XIAP).Fórmula:C29H32N2O4SForma y color:SolidPeso molecular:504.64Penehyclidine hydrochloride
CAS:Penehyclidine hydrochloride: M1/M3 antagonist, activates NF-κB, anti-inflammatory, anticholinergic.Fórmula:C20H30ClNO2Pureza:99.79% - 99.91%Forma y color:SolidPeso molecular:351.91Thioxodihydroquinazolinone-19
CAS:Thioxodihydroquinazolinone-19 triggers apoptosis in A2780cis ovarian cancer cells and enhances cisplatin efficacy.Fórmula:C16H14N2OSPureza:98%Forma y color:SolidPeso molecular:282.36Anticancer agent 99
CAS:Anticancer agent 99 targets HepG2 cells, IC50 at 35.9 μM, induces apoptosis and hinders cell growth.Fórmula:C19H20F3N3O2Forma y color:SolidPeso molecular:379.38Pracinostat dihydrochloride
CAS:Pracinostat dihydrochloride is a highly effective histone deacetylase (HDAC) inhibitor with IC₅₀ values ranging from 40 to 140 nM, utilized in cancer research. Additionally, it inhibits metallo-β-lactamase domain-containing protein 2 (MBLAC2) hydrolase activity with an EC₅₀ of less than 10 nM.Fórmula:C20H32Cl2N4O2Forma y color:SolidPeso molecular:431.40Caspase-3/7 activator 2
Caspase-3/7 activator 2 triggers apoptosis with tumor selectivity and anti-proliferative properties.Fórmula:C32H34N2O7Forma y color:SolidPeso molecular:558.62MRS 2693 trisodium salt
CAS:MRS 2693 trisodium salt is a P2Y6 agonist.Fórmula:C9H22IN5O12P2Pureza:98%Forma y color:SolidPeso molecular:581.15Luxeptinib
CAS:Luxeptinib (CG-806) is an oral, non-covalent pan-FLT3/BTK inhibitor for acute myeloid leukemia.Fórmula:C25H17F4N5O2Forma y color:SolidPeso molecular:495.43STK17A/B-IN-1
CAS:STK17A/B-IN-1 (compound 9) is an orally active, potent, and selective inhibitor of STK17A/B, demonstrating an IC50 of 23 nM for STK17A. This compound is utilized in tumor research.Fórmula:C26H27N7OForma y color:SolidPeso molecular:453.54
