c-Myc
Los inhibidores de c-Myc se dirigen a la proteína c-Myc, un factor de transcripción que juega un papel crucial en el crecimiento celular, la proliferación y la apoptosis. c-Myc regula la expresión de numerosos genes involucrados en el ciclo celular y a menudo está sobreexpresado en varios tipos de cáncer, lo que lleva a una proliferación celular descontrolada y al crecimiento tumoral. Inhibir c-Myc puede interrumpir estos procesos, induciendo el arresto del ciclo celular y la apoptosis en células cancerosas. Los inhibidores de c-Myc son herramientas importantes en la investigación del cáncer y el desarrollo terapéutico. En CymitQuimica, ofrecemos una amplia gama de inhibidores de c-Myc de alta calidad para apoyar su investigación en oncología, regulación del ciclo celular y control transcripcional.
Se han encontrado 69 productos de "c-Myc"
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Ceramides Mixture
CAS:<p>Ceramides Mixture: endogenous, regulates cell cycle, growth, and telomerase activity, with hydroxy/non-hydroxy fatty acids.</p>Fórmula:C36H71NO4Pureza:98%Forma y color:SolidPeso molecular:581.967FIDAS-5
CAS:<p>FIDAS-5 is an orally active methionine adenosyltransferase 2A (MAT2A) inhibitor with an IC50 of 2.1 μM. Cost-effective and quality-assured.</p>Fórmula:C15H13ClFNPureza:97.66% - 98.3%Forma y color:SolidPeso molecular:261.72Eragidomide
CAS:<p>Eragidomide (Cereblon modulator 1) is a CRBN E3 ligase modulator, specifically binds to CRBN, thereby affecting the activity of the ubiquitin E3 ligase complex.</p>Fórmula:C22H18ClF2N3O4Pureza:97.51% - 99.63%Forma y color:SolidPeso molecular:461.85MYCi361
CAS:<p>MYCi361 (NUCC-0196361) is an inhibitor of MYC (binding to MYC with Kd of 3.2 μM).</p>Fórmula:C26H16ClF9N2O2Pureza:99.52%Forma y color:SolidPeso molecular:594.86MYCMI-6
CAS:<p>MYCMI-6 inhibits MYC:MAX, reduces tumor growth, triggers apoptosis, minimal side effects.</p>Fórmula:C20H19N7OPureza:99.23%Forma y color:SolidPeso molecular:373.41MYCi975
CAS:<p>MYCi975 (NUCC-0200975) is an orally active inhibitor of MYC.</p>Fórmula:C25H16Cl2F6N2O2Pureza:99.3% - 99.82%Forma y color:SolidPeso molecular:561.3Saxagliptin hydrate
CAS:<p>Saxagliptin hydrate (Onglyza hydrate) is a selective and reversible DPP4 inhibitor (IC50: 26 nM; Ki: 1.3 nM).</p>Fórmula:C18H25N3O2·H2OPureza:99.52%Forma y color:SolidPeso molecular:333.43KJ Pyr 9
CAS:<p>KJ Pyr 9 is an MYC inhibitor (Kd: 6.5 nM in vitro assay).</p>Fórmula:C22H15N3O4Pureza:99.56% - ≥98%Forma y color:SolidPeso molecular:385.37FIDAS-3
CAS:<p>FIDAS-3, a stilbene derivative and potent Wnt inhibitor with an IC50 of 4.9 μM for methionine S-adenosyltransferase 2A (MAT2A), exhibits anticancer activities</p>Fórmula:C16H15F2NPureza:97.75%Forma y color:SolidPeso molecular:259.29APTO-253
CAS:<p>APTO-253 (LOR-253) inhibits c-Myc expression, stabilizes G-quadruplex DNA, and induces cell cycle arrest and apoptosis in acute myeloid leukemia cells.</p>Fórmula:C22H14FN5Pureza:98.73%Forma y color:SolidPeso molecular:367.38c-Myc inhibitor 10
CAS:<p>c-Myc inhibitor 10 enhances cell potency with improved permeability from methylated morpholine nitrogen.</p>Fórmula:C28H38N6O3Forma y color:SolidPeso molecular:506.64c-Myc inhibitor 5
<p>DA3: Fluorescent c-Myc inhibitor, targets c-MYC G-quadruplex (K D 16 μM), selective, suppresses c-MYC expression.</p>Fórmula:C30H46N12Forma y color:SolidPeso molecular:574.77Anti-c-myc Antibody (9E10)
<p>Anti-c-myc Antibody (9E10) is a chimeric mouse IgG1 antibody targeting human c-myc.</p>Forma y color:Odour LiquidAnticancer agent 263
<p>Anticanceragent 263 (compound 7) is an effective anticancer agent. It binds with the G-quadruplex DNA (G4) sequence 22-mer Pu22 (a c-Myc DNA analog). As a structural modulator, Anticanceragent 263 significantly enhances the formation of protein α-helices and has the capacity to form a supramolecular network. Furthermore, Anticanceragent 263 exhibits no cytotoxicity.</p>Fórmula:C13H20N2O6Forma y color:SolidPeso molecular:300.308Cotylenin A
CAS:<p>Cotylenin A is a phenanthraquinone compound that synergistically works with vitamin K2 to induce monocyte differentiation and growth arrest. It also inhibits c-Myc expression while inducing cyclin G2 expression in human leukemia HL-60 cells. Cotylenin A is applicable in acute myeloid leukemia research.</p>Fórmula:C33H50O11Forma y color:SolidPeso molecular:622.744H122
<p>H122 is a TEADPROTAC degrader effective in degrading TEAD1 with a DC50 of 3 nM, and it shows strong affinity for TEAD2, TEAD3, and TEAD4 with Ki values of 2.0, 3.6, and 1.6 nM, respectively. H122 also downregulates Myc expression and inhibits the growth of MSTO-211H and NCI-H226 cells, with IC50 values of 21.3 nM and 0.6 nM, respectively, demonstrating antitumor activity in mouse models. (Pink: ligand for target protein; Black: linker; Blue: ligand for E3 ligaseCereblon)</p>Fórmula:C45H45ClFN5O8Forma y color:SolidPeso molecular:838.319Methylcarbamyl PAF C-8
<p>Methylcarbamyl PAF C-8 is resistant to degradation by PAF-AH and has a half-life of over 100 minutes in platelet-poor plasma, exhibiting platelet aggregation activity. In NRK-49 cells overexpressing PAF receptor, it induces the expression of c-myc, c-fos, and activates mitogen-activated protein kinase (MAPK). Furthermore, Methylcarbamyl PAF C-8 can induce G1 phase cell cycle arrest. This compound shows potential for research in cardiovascular and anti-cancer applications.</p>Forma y color:Odour SolidRA-V
<p>RA-V is a natural product that can be used as a reference standard.</p>Fórmula:C160H202N24O41Forma y color:SolidPeso molecular:3117.5VGN50
<p>VGN50 is a bioactive molecule that mimics the function of K-Rta, capable of downregulating MYC-mediated gene transcription. VGN50 exhibits antitumor activity.</p>Fórmula:C121H218N46O32Peso molecular:2827.68453MYC-IN-2
CAS:<p>MYC-IN-2 is a protein-protein inhibitor targeting the MYC protein, designed for use in cancer research.</p>Fórmula:C25H17N3O2SForma y color:SolidPeso molecular:423.49
