Cromatina / Epigenética
Los inhibidores de cromatina/epigenética son compuestos que modulan la estructura y función de la cromatina o interfieren con modificaciones epigenéticas, como la metilación del ADN y la modificación de histonas. Estos inhibidores son herramientas esenciales para estudiar la regulación de la expresión génica y el papel de la epigenética en enfermedades como el cáncer, los trastornos neurológicos y las anomalías del desarrollo. Al dirigirse a los procesos epigenéticos, estos inhibidores pueden alterar los patrones de expresión génica y ofrecer nuevas vías terapéuticas. En CymitQuimica, ofrecemos una amplia selección de inhibidores de cromatina/epigenética de alta calidad para apoyar su investigación en biología molecular, genética y epigenética.
Subcategorías de "Cromatina / Epigenética"
Se han encontrado 2245 productos de "Cromatina / Epigenética"
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Izilendustat hydrochloride
CAS:<p>Izilendustat hydrochloride inhibits prolyl hydroxylase, stabilizing HIF-1α/HIF-2, with potential to treat various HIF-1α diseases.</p>Fórmula:C22H29Cl2N3O4Forma y color:SolidPeso molecular:470.396-Bromo-3-methyl-1,4-dihydroquinazolin-2-one
CAS:<p>CHEMBRDG-BB 7118966 is an inhibitor of Bromodomain-containing protein 4 (human).</p>Fórmula:C9H9BrN2OPureza:99.28%Forma y color:SolidPeso molecular:241.08EB-47 dihydrochloride
CAS:EB 47 is an effective inhibitor of PARP-1 (IC50: 45 nM).Fórmula:C24H29Cl2N9O6Forma y color:SolidPeso molecular:610.45SC-43
CAS:<p>SC-43 is a potent and orally active agonist of SHP-1 (PTPN6).</p>Fórmula:C21H13ClF3N3O2Pureza:98.44%Forma y color:SolidPeso molecular:431.8MS31 trihydrochloride
<p>MS31 trihydrochloride: a selective SPIN1 inhibitor, binds H3K4me3 (IC50: 77-243 nM), non-toxic to healthy cells.</p>Fórmula:C20H30Cl3N3O2Forma y color:SolidPeso molecular:450.83WM-8014
CAS:<p>WM-8014 (MOZ-IN-3) is an inhibitor of MOZ(IC50=55 nM), a member of histone acetyltransferases.</p>Fórmula:C20H17FN2O3SPureza:99.64%Forma y color:SolidPeso molecular:384.42PF 477736
CAS:<p>PF 477736 (PF-736,PF-00477736) is a specifc, effective and ATP-competitive Chk1 inhibitor (Ki: 0.49 nM ) and also inhibits FGFR3, Aurora-A, VEGFR2, Flt3, Fms (</p>Fórmula:C22H25N7O2Pureza:97.58% - 99.94%Forma y color:SolidPeso molecular:419.48GSK3685032
CAS:<p>GSK3685032 is a non-covalent and selective DNMT1 inhibitor(IC50 = 36 nM).</p>Fórmula:C22H24N6OSPureza:98.56% - 99.49%Forma y color:SolidPeso molecular:420.53653-47
CAS:<p>653-47 enhances the effects of 666-15 on inhibiting CREB and is a mild CREB inhibitor itself (IC50: 26.3μM).</p>Fórmula:C20H19ClN2O3Forma y color:SolidPeso molecular:370.83Abrocitinib
CAS:<p>Abrocitinib (PF-04965842) (PF-04965842) is a potent, specific and orally-active JAK1 inhibitor (IC50s: 29/803 nM for JAK1/2).</p>Fórmula:C14H21N5O2SPureza:99.09% - 99.91%Forma y color:SolidPeso molecular:323.41GSK 690 Hydrochloride
CAS:<p>GSK 690 (Hydrochloride) is a reversible lysine specific demethylase 1 (LSD1) inhibitor with a Kd value of 9 nM and IC 50 of 37 nM.</p>Fórmula:C24H24ClN3OPureza:98%Forma y color:SolidPeso molecular:405.92JQ-1 (carboxylic acid)
CAS:<p>JQ-1 (carboxylic acid) is a cell-permeable BRD4 inhibitor with IC50s of 77 nM for BRD4(1) and 33 nM for BRD4(2)</p>Fórmula:C19H17ClN4O2SPureza:99.14% - 99.9%Forma y color:SolidPeso molecular:400.88Aurora kinase inhibitor-3
CAS:<p>Aurora kinase inhibitor-3 (Aurora Kinase Inhibitor III) is a potent inhibitor of Aurora A kinase (IC50 = 42 nM).1 It is selective for Aurora A over BMX, BTK,</p>Fórmula:C21H18F3N5OPureza:98.91%Forma y color:SolidPeso molecular:413.4Daphnetin
CAS:<p>Daphnetin (7,8-Dihydroxycoumarin), a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 μM), PKA (IC50: 9.33 μM),</p>Fórmula:C9H6O4Pureza:97.47% - 99.8%Forma y color:SolidPeso molecular:178.14WHI-P97
CAS:WHI-P97 is a rationally designed potent inhibitor of JAK-3.Fórmula:C16H13Br2N3O3Pureza:99.93%Forma y color:SolidPeso molecular:455.1GN44028
CAS:<p>GN44028 is a HIF-1 inhibitor with an IC50 of 14 nM, stopping HIF-1α activity but not mRNA or protein levels, or dimerization.</p>Fórmula:C18H15N3O2Pureza:99.52%Forma y color:SolidPeso molecular:305.33TCS7010
CAS:<p>TCS7010 (Aurora A Inhibitor I) is a novel, potent, and selective inhibitor of Aurora A with IC50 of 3.4 nM in a cell-free assay.</p>Fórmula:C31H31ClFN7O2Pureza:98.49% - 99.62%Forma y color:SolidPeso molecular:588.07CPI-1205
CAS:<p>CPI-1205 是一种高效的选择性 EZH2 抑制剂（IC50：0.002 μM，EC50：0.032 μM）。</p>Fórmula:C27H33F3N4O3Pureza:98.71% - 99.7%Forma y color:SolidPeso molecular:518.57XAV-939
CAS:<p>XAV-939 (NVP-XAV939) shows the selective inhibition against Wnt/β-catenin-mediated transcription by tankyrase1/2 inhibition (IC50: 11/4 nM in cell-free assay).</p>Fórmula:C14H11F3N2OSPureza:97.47% - 99.67%Forma y color:SolidPeso molecular:312.31Pyridone 6
CAS:<p>Pyridone 6, a selective JAK1/2/3 and Tyk2 inhibitor with IC50s: JAK1=15 nM, JAK2=1 nM, JAK3 (Ki=5 nM), Tyk2=1 nM; weakly binds other kinases (130 nM-10 μM).</p>Fórmula:C18H16FN3OPureza:97.1% - 98.74%Forma y color:SolidPeso molecular:309.34
