CCR
Los receptores de quimiocinas C-C (CCRs) son un grupo de GPCR que responden a las quimiocinas, moléculas de señalización que guían la migración de células inmunitarias hacia sitios de inflamación o infección. Los CCR desempeñan un papel crucial en las respuestas inmunitarias, la inflamación y el desarrollo de diversas enfermedades, incluidas las enfermedades autoinmunes y el cáncer. La modulación de la actividad de los CCR se está explorando como una estrategia terapéutica para afecciones como la artritis reumatoide, la esclerosis múltiple y la infección por VIH. En CymitQuimica, ofrecemos una gama de moduladores de CCR de alta calidad para apoyar su investigación en inmunología, inflamación y desarrollo terapéutico.
Se han encontrado 136 productos de "CCR"
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PNU-177864 hydrochloride
CAS:<p>PNU-177864 hydrochloride is a potent, selective and orally active antagonist of dopamine D3 receptor.</p>Fórmula:C18H22ClF3N2O3SPureza:99.95%Forma y color:SolidPeso molecular:438.89PNU-177864
CAS:<p>PNU-177864 is a selective dopamine D3 receptor antagonist.</p>Fórmula:C18H21F3N2O3SPureza:99.92%Forma y color:SolidPeso molecular:402.43BMS-457
CAS:<p>BMS-457 is a potent, CCR1-selective antagonist.</p>Fórmula:C24H35ClN2O4Pureza:98%Forma y color:SolidPeso molecular:451AZD-1678
CAS:<p>AZD-1678 is a potent CCR4 receptor antagonist.</p>Fórmula:C11H8Cl2FN3O3SForma y color:SolidPeso molecular:352.17MLN3126
CAS:<p>MLN3126: Oral CCR9 blocker, hinders CCL25-triggered chemotaxis/thymocyte calcium influx, IC50 of 6.3 nM.</p>Fórmula:C21H19ClN2O5SForma y color:SolidPeso molecular:446.9JNJ-27141491
CAS:<p>JNJ-27141491 is a potent, noncompetitive antagonist of human CCR2.</p>Fórmula:C17H15F2N3O3SPureza:98%Forma y color:SolidPeso molecular:379.38TAK-220
CAS:<p>TAK-220: Oral CCR5 antagonist. IC50: 3.5 nM (RANTES), 1.4 nM (MIP-1α).</p>Fórmula:C31H41ClN4O3Pureza:98%Forma y color:SolidPeso molecular:553.14C-021 dihydrochloride
CAS:<p>C-021 dihydrochloride is a potent CCR4 antagonist. It potently inhibits functional chemotaxis in human and mouse with IC50s of 140 nM and 39 nM.</p>Fórmula:C27H43Cl2N5O2Pureza:98.67%Forma y color:SolidPeso molecular:540.57CCR1 antagonist 6
CAS:<p>CCR1 antagonist 6 is a CCR1 antagonist (IC50: 3 nM).</p>Fórmula:C21H23ClN4O3SPureza:99.02% - 99.15%Forma y color:SolidPeso molecular:446.95Ancriviroc
CAS:<p>Ancriviroc (SCH-351125) is an orally bioavailable small molecule chemokine receptor CCR5 antagonist.Cost-effective and quality-assured.</p>Fórmula:C28H37BrN4O3Pureza:99.76% - 99.82%Forma y color:SolidPeso molecular:557.52BMS CCR2 22
CAS:<p>BMS CCR2 22 is a potent and selective antagonist of CCR2 with calcium flux IC50 of 18 nM, chemotaxis IC50 of 1 nM, and binding IC50 of 5.1 nM.</p>Fórmula:C28H34F3N5O4SPureza:99.65%Forma y color:SolidPeso molecular:593.66CCR2 antagonist 5
CAS:<p>JNJ-41443532: oral hCCR2 antagonist, IC50=37 nM, anti-chemotaxis, treats inflammation & diabetes.</p>Fórmula:C22H25F3N4O3SPureza:99.09%Forma y color:SolidPeso molecular:482.52BMS-817399
CAS:<p>BMS-817399: oral CCR1 antagonist with binding and chemotaxis inhibition IC50s, potential for rheumatoid arthritis research.</p>Fórmula:C23H36ClN3O4Pureza:99.7%Forma y color:SolidPeso molecular:454SB 328437
CAS:<p>SB 328437 ((S)-methyl 2-(1-naphthamido)-3-(4-nitrophenyl)propanoate) is an effective and selective antagonist of CCR3 (IC50 = 4.5 nM).</p>Fórmula:C21H18N2O5Pureza:99.54%Forma y color:SolidPeso molecular:378.38Cosalane
CAS:<p>Cosalane (NSC 658586) is an HIV replication inhibitor and an inhibitor of chemokine receptor 7 (CCR7) signalling in humans and mice.</p>Fórmula:C45H60Cl2O6Pureza:99.53% - 99.78%Forma y color:SolidPeso molecular:767.86GSK2239633A
CAS:<p>GSK2239633A is an allosteric antagonist of CC-chemokine receptor 4 (CCR4) with a pIC50 of 7.96 for the binding of [125I]-TARC to human CCR4.</p>Fórmula:C24H25ClN4O5S2Pureza:99.82%Forma y color:SolidPeso molecular:549.06VCH-286
CAS:<p>VCH-286 is a C-C chemokine receptor type 5 (CCR5) receptor antagonist.</p>Fórmula:C34H50F2N4O3Pureza:98%Forma y color:SolidPeso molecular:600.78PF-04634817 succinate
CAS:<p>PF-0463481 succinate is a potent and orally active dual antagonist of CCR2/CCR5 with comparable human and rodent CCR2 potency with IC50 of 20.8 nM.</p>Fórmula:C29H42F3N5O7Pureza:98%Forma y color:SolidPeso molecular:629.67CCR2 antagonist 4
CAS:<p>CCR2 antagonist 4 (Teijin compound 1) is a potent and specific antagonist of CCR2(IC50s of 180 nM), and potently inhibits MCP-1-induced chemotaxis(IC50 of 24 nM</p>Fórmula:C21H21ClF3N3O2Pureza:99.86%Forma y color:SolidPeso molecular:439.86CCR4 antagonist 4
CAS:<p>CCR4 Antagonist 4 (Compound 22) is a potent and selective antagonist of the CC chemokine receptor-4 (CCR4), displaying an IC50 value of 0.02 μM. It also inhibits MDC-mediated chemotaxis and Ca2+ mobilization, with IC50 values of 0.007 μM and 0.003 μM, respectively. This compound is utilized in research on allergic inflammation [1].</p>Fórmula:C24H27Cl2N7OForma y color:SolidPeso molecular:500.42
