CFTR
El CFTR es una proteína de canal de cloruro que regula el transporte de iones cloruro y bicarbonato a través de las membranas de las células epiteliales, desempeñando un papel crucial en el mantenimiento del equilibrio de fluidos en los tejidos. Las mutaciones en el gen CFTR conducen a la fibrosis quística, un trastorno genético caracterizado por la producción de moco espeso que puede obstruir las vías respiratorias y provocar graves problemas respiratorios y digestivos. En CymitQuimica, ofrecemos una selección de moduladores de CFTR para apoyar su investigación en fibrosis quística, transporte de iones y trastornos genéticos.
Se han encontrado 67 productos para "CFTR".
Filtrar por
Porcentaje de pureza
0
100
|
0
|
50
|
90
|
95
|
100
- Precio más bajo
- Precio más alto
- Pureza más baja
- Pureza más alta
- Entrega estimada más rápida
Glibenclamide
CAS:Glibenclamide (Glyburide) is an antidiabetic sulfonylurea derivative with actions similar to those of chlorpropamide.Fórmula:C23H28ClN3O5SPureza:99.05% - 99.75%Forma y color:White SolidPeso molecular:494.004Elexacaftor
CAS:Elexacaftor (VX-445) is a cystic fibrosis transmembrane conductance regulator (CFTR) corrector.Cost-effective and quality-assured.Fórmula:C26H34F3N7O4SPureza:98.87% - 99.87%Forma y color:SolidPeso molecular:597.653CFTR activator 2
CAS:CFTR activator 2 (WAY-326769) is an activator of mutant CFTR (cystic fibrosis transmembrane conductance regulator), which increases ion transport activity and can be used for research into cystic fibrosis (CF).Fórmula:C27H27N3O3Pureza:99.70%Forma y color:SolidPeso molecular:441.52H2-Gamendazole
CAS:H2-Gamendazole: inhibits spermatogenesis, cancer therapy, targets heat shock proteins & EF1α, regulates Hsp90.Fórmula:C18H13Cl2F3N2O2Pureza:97.39%Forma y color:SolidPeso molecular:417.209Cavosonstat
CAS:Cavosonstat (N91115) is an oral GSNOR inhibitor aiding CFTR in cystic fibrosis.Fórmula:C16H10ClNO3Pureza:99.64%Forma y color:Yellow SolidPeso molecular:299.708Crofelemer
CAS:Crofelemer (Provir) is an orally active antidiarrheal agent. It targets the cystic fibrosis transmembrane conductance regulator (CFTR) and calcium-activated chloride channels (CACC), which are responsible for chloride and fluid secretion in the gastrointestinal tract. Crofelemer is applicable for research in diarrhea-related conditions.Forma y color:SolidAstressin 2B
CAS:CRF2 antagonist with IC50 of 1.3 nM; >500 nM for CRF1. Aids gastric emptying.Fórmula:C183H307N49O53Pureza:98%Forma y color:SolidPeso molecular:4041.69Urocortin III, mouse (free acid)
Urocortin III (mouse) is a CRF2 receptor agonist that slows gastric emptying without affecting colonic transit.Fórmula:C186H311N51S2Peso molecular:4171.26Zatonacaftor
CAS:Zatonacaftor, a cystic fibrosis transmembrane regulator (CFTR) modulator, is utilized in the research of cystic fibrosis [1] [2].Fórmula:C24H27N3O4SForma y color:SolidPeso molecular:453.55(R)-Crinecerfont
CAS:4-(2-chloro-4-methoxy-5-methylphenyl)-N-[(1A)-2-cyclopropyl-1-(3-fluoro-4-methylphenyl)ethyl]-5-methyl-N-(2-propyn-1-yl)-2-thiazolamine is an enantiomericFórmula:C27H28ClFN2OSPureza:98.51%Forma y color:Orange SolidPeso molecular:483.04kCAL01
CAS:kCAL01 is a CAL inhibitor with a Ki value of 2.3 μM and holds potential for research in cystic fibrosis (CF).Fórmula:C36H57N11O9Forma y color:SolidPeso molecular:787.91Vanzacaftor
CAS:Vanzacaftor is a CFTR modulator improving protein processing and surface trafficking, restoring chloride transport and aiding cystic fibrosis therapy research.Fórmula:C32H39N7O4SPureza:99.14%Forma y color:White SolidPeso molecular:617.76(Rac)-Tezacaftor
CAS:(Rac)-Tezacaftor, a racemate, corrects F508del CFTR for cystic fibrosis research.Fórmula:C26H27F3N2O6Forma y color:SolidPeso molecular:520.5CP-628006
CAS:CP-628006 is a small molecule CFTR potentiator that effectively restores ATP-dependent channel gating to G551D-CFTR, the mutant form found in cystic fibrosis.Fórmula:C32H35F3N2O2Forma y color:SolidPeso molecular:536.639WAY-326766
CAS:WAY-326766 increases ion transport through mutant CFTR and can be used to alter the lifespan of eukaryotes.WAY-326766 can be used to treat cystic fibrosis (CF).Fórmula:C21H23N3O5Pureza:99.87%Forma y color:SolidPeso molecular:397.4244Crinecerfont hydrochloride
CAS:SSR-125543, a potent CRF1 receptor non-peptide antagonist, effective in CAH research, taken orally.Fórmula:C27H29Cl2FN2OSForma y color:SolidPeso molecular:519.501Tezacaftor
CAS:Tezacaftor (VX661) is a small molecule that can be used as a corrector of the cystic fibrosis transmembrane conductance regulator (CFTR) gene function.Fórmula:C26H27F3N2O6Pureza:98.84% - >99.99%Forma y color:SolidPeso molecular:520.4976KM11060
CAS:KM11060 is a novel corrector of the F508del-CFTR trafficking defect, Correcting F508del-CFTR trafficking, increasing the amount of functional CFTR at the plasmaFórmula:C19H17Cl2N3O2SPureza:99.08%Forma y color:SolidPeso molecular:422.328PPQ-102
CAS:PPQ-102 (CFTR Inhibitor), an effective CFTR inhibitor, can completely inhibit CFTR chloride current (IC50: 90 nM).Fórmula:C26H22N4O3Pureza:98.80% - ≥95%Forma y color:Yellow SolidPeso molecular:438.4779IOWH-032
CAS:IOWH-032 (IOWH032) , a synthetic CFTR inhibitor, has been investigated for the treatment of cholera, diarrhea, and secretory diarrhea.Fórmula:C22H15Br2N3O4Pureza:99% - >99.99%Forma y color:SolidPeso molecular:545.18
