Canal de cloruro
Los canales de cloruro son proteínas de membrana que controlan el movimiento de los iones de cloruro a través de las membranas celulares, desempeñando un papel vital en el mantenimiento del volumen celular, la excitabilidad eléctrica y el equilibrio ácido-base. La desregulación de los canales de cloruro está relacionada con enfermedades como la fibrosis quística, la epilepsia y los trastornos renales. En CymitQuimica, ofrecemos una variedad de moduladores de canales de cloruro para apoyar su investigación en el transporte de iones, la homeostasis celular y los mecanismos de enfermedades.
Se han encontrado 49 productos de "Canal de cloruro"
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Niflumic acid
CAS:<p>Niflumic acid (Nifluril) is a Ca2+-activated Cl- channel blocker and an analgesic and anti-inflammatory agent used in the therapy of rheumatoid arthritis.</p>Fórmula:C13H9F3N2O2Pureza:99.47%Forma y color:SolidPeso molecular:282.22T16Ainh-A01
CAS:<p>T16Ainh-A01 is a potent TMEM16A chloride channel inhibitor with a 1 μM IC50, targeting CaCC.</p>Fórmula:C19H20N4O3S2Pureza:97.18% - 98.15%Forma y color:SolidPeso molecular:416.52Afoxolaner
CAS:<p>Afoxolaner is an isoxazoline insecticide/acaricide against Ixodes scapularis in dogs.</p>Fórmula:C26H17ClF9N3O3Pureza:99.1% - 99.38%Forma y color:SolidPeso molecular:625.87DCPIB
CAS:<p>DCPIB, a known specific and potent inhibitor of volume-regulated anion channels (VRAC),DCPIB displayed superior selectivity toward TRESK with an IC50 of 0.14 μM</p>Fórmula:C22H28Cl2O4Pureza:99.79% - 99.87%Forma y color:SolidPeso molecular:427.36Flufenamic acid
CAS:<p>Flufenamic acid (Arlef) is an anthranilic acid derivative with analgesic, anti-inflammatory, and antipyretic properties.</p>Fórmula:C14H10F3NO2Pureza:98.68%Forma y color:White To Light Yellow Crystalline PowderPeso molecular:281.23Endovion
CAS:<p>Endovion (NS3728) is a pharmacological anion channel and an Anoctamin-1 (ANO 1) channel inhibitor. Endovion is also the specific VRAC/VSOAC blocker.</p>Fórmula:C16H9BrF6N6OPureza:98.51%Forma y color:SolidPeso molecular:495.18Meticrane
CAS:<p>Meticrane (Arresten) is a sulphonamide-derivative with thiazide-like diuretic activity.</p>Fórmula:C10H13NO4S2Pureza:99.16%Forma y color:SolidPeso molecular:275.34Halothane
CAS:<p>Halothane (Anestan) 可以减弱内皮依赖性舒张作用。</p>Fórmula:C2HBrClF3Pureza:98.50% - >99.99%Forma y color:Colorless Volatile Liquid Density 1 875 G / Cm3 Boiling Point 122 4°F (50 2°C) NoncombustiblePeso molecular:197.38Eact
CAS:<p>Eact is a potent TMEM16A activator that also triggers TRPV1, causing itch, pain, and heat sensitivity.</p>Fórmula:C22H24N2O5SPureza:98.14%Forma y color:SolidPeso molecular:428.5NS1652
CAS:<p>NS1652 is an anion conductance inhibitor. NS1652 blocks chloride channel has an IC50 of 1.6 μM in human and mouse red blood cells.</p>Fórmula:C15H11F3N2O3Pureza:99.62%Forma y color:SolidPeso molecular:324.25Chlorotoxin
CAS:<p>Chlorotoxin: 36-amino acid peptide from deathstalker scorpion venom; blocks small chloride channels.</p>Fórmula:C158H249N53O47S11Pureza:98%Forma y color:SolidPeso molecular:3995.71Chlorotoxin(linear)
<p>Chlorotoxin(linear): 36-amino-acid peptide from Egyptian scorpion venom, used in research as chloride channel blocker.</p>Fórmula:C158H256N52O48S11Pureza:98%Forma y color:SolidPeso molecular:4004.76Chlorotoxin TFA
<p>Chlorotoxin TFA, a scorpion venom peptide, blocks chloride channels and has anti-cancer properties.</p>Fórmula:C160H250F3N53O49S11Forma y color:SolidPeso molecular:4109.74GaTx2
CAS:<p>High-affinity ClC-2 blocker (KD ~50 pM), selective over other ClCs/CFTR/GABAC/CaCC/KV1.2; slows activation, no effect on open channels.</p>Fórmula:C125H199N39O47S6Pureza:98%Forma y color:SolidPeso molecular:3192.54Ion Channel Targeted Library
<p>A unique collection of 931 compounds targeting ion channels for research in ion channels-related diseases and ion channel drug discovery;</p>Forma y color:Odour SolidANO1-IN-4
CAS:<p>ANO1-IN-4 (Compound 10bm) is a reversible inhibitor of the calcium-activated chloride channel transmembrane protein 16A (TMEM16A, also known as ANO1), with an IC50 of 0.030 µM. It demonstrates good metabolic stability in rat liver microsomes and can inhibit spontaneous contractions in isolated mouse ileum.</p>Fórmula:C19H19BrF2N2O2SForma y color:SolidPeso molecular:457.33Lubiprostone hemiketal
CAS:<p>Lubiprostone (hemiketal) (RU-0211 (hemiketal)), a selective activator of the chloride channel 2 (CLCN2), facilitates the treatment of chronic idiopathic constipation and opioid-induced constipation. It functions by enhancing CLCN2 channel activity, which boosts chloride ion secretion in the intestines, subsequently increasing fluid secretion and improving intestinal peristalsis. Additionally, Lubiprostone (hemiketal) may be utilized in research related to chronic constipation and cancer.</p>Fórmula:C20H32F2O5Forma y color:SolidPeso molecular:390.46Adjudin
CAS:<p>Adjudin (AF-2364) is a small molecule compound known to possess antispermatogenic function, attenuates microglia activation by suppression of the NF-κB pathway.</p>Fórmula:C15H12Cl2N4OPureza:96.51% - ≥95%Forma y color:SolidPeso molecular:335.19Fenamic acid
CAS:<p>Fenamic acid (N-Phenylanthranilic acid) is a chloride channel blocker that causes renal papillary necrosis in rats.</p>Fórmula:C13H11NO2Pureza:99.6%Forma y color:White To Off-White Crystalline PowderPeso molecular:213.2319Irisolidone
CAS:<p>Irisolidone is a potent volume-regulated anion channel (VRAC) current inhibitor, it exhibits high efficacy for VRAC blockade with IC50s of 5-13 μM.</p>Fórmula:C17H14O6Pureza:99.41% - 99.87%Forma y color:SolidPeso molecular:314.29
