Glucoquinasa
La glucocinasa (GK) es una enzima que cataliza la fosforilación de la glucosa a glucosa-6-fosfato, un paso crítico en la glucólisis. La GK se expresa predominantemente en el hígado y el páncreas, donde desempeña un papel clave en la regulación de los niveles de glucosa en sangre. Los inhibidores de GK son de interés en el estudio de trastornos metabólicos como la diabetes, ya que pueden modular el metabolismo de la glucosa y la secreción de insulina. En CymitQuimica, ofrecemos inhibidores de glucocinasa para apoyar su investigación en diabetes, metabolismo y desarrollo terapéutico.
Se han encontrado 57 productos de "Glucoquinasa"
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MK-0941 free base
CAS:MK-0941: an oral glucokinase activator for type 2 diabetes with potent glucose-lowering effects.Fórmula:C21H24N4O6SPureza:98.75%Forma y color:SolidPeso molecular:460.5Dorzagliatin
CAS:Dorzagliatin (HMS5552) is a dual-acting glucokinase (GK) activator. It also improves glycaemic control and pancreatic β-cell function in type 2 diabetes.Fórmula:C22H27ClN4O5Pureza:98.67% - 99.45%Forma y color:SolidPeso molecular:462.93Oxfendazole
CAS:Oxfendazole (RS-8858), a broad spectrum benzimidazole anthelmintic, protects livestock against roundworm, strongyles and pinworms.Fórmula:C15H13N3O3SPureza:98.99% - 99.17%Forma y color:White To Yellowish PowderPeso molecular:315.35WAY-640509
CAS:WAY-640509 is a glucocerebrosidase inhibitor.Fórmula:C25H23N5O4SPureza:99.36%Forma y color:SolidPeso molecular:489.55MitoPQ
CAS:MitoPQ (MitoParaquat) inhibits insulin-stimulated glucose uptake and plasma membrane translocation in myotubes and can be used to study oxidative stress.Fórmula:C39H46I3N2PPureza:99.87% - 99.91%Forma y color:SolidPeso molecular:954.48KAN0438757
CAS:<p>KAN0438757 is a selective and potent inhibitor of the metabolic kinase PFKFB3 with an IC50 of 0.19 μM.</p>Fórmula:C21H18FNO7SPureza:99.34%Forma y color:SolidPeso molecular:447.43ML251
CAS:ML251, potent inhibitor, targets T. brucei PFK (IC50=0.37μM) & T. cruzi PFK (IC50=0.13μM), aids parasite research.Fórmula:C17H13Cl2N3O4SPureza:99.87%Forma y color:SolidPeso molecular:426.27WAY-615145
CAS:WAY-615145 is a compound that activates glucokinase.Fórmula:C16H18N2OSPeso molecular:286.39ML266
CAS:<p>ML266: GCase chaperone, non-inhibiting, IC50=2.5 µM, aids mutant protein transport, may help in Gaucher disease study.</p>Fórmula:C24H22BrN3O4Pureza:99.58%Forma y color:SolidPeso molecular:496.35AP-III-a4 hydrochloride
CAS:AP-III-a4 hydrochloride (ENOblock hydrochloride) is a direct enolase (enolase) inhibitor that inhibit metastasis and affect glucose homeostasis.Fórmula:C31H44ClFN8O3Pureza:98%Forma y color:SolidPeso molecular:631.18ADP-specific glucokinase
CAS:<p>ADP-specific glucokinase, expressed in thermophilic archaea, is an ADP-specific enzyme that catalyzes the conversion of glucose to glucose-6-phosphate, thereby facilitating glycolysis. This enzyme can activate T cells and enhance the phagocytic activity of macrophages. It is used in research related to metabolic disorders, neurological diseases, and tumors.</p>Forma y color:SolidNeuron-specific enolase, Human
Neuron-specific enolase, Human (EC 4.2.1.11), is an enolase enzyme that serves as a biomarker for traumatic brain injury (TBI), stroke following cardiac arrest, hypoxic encephalopathy, and acute spinal cord injury (SCI).Forma y color:Odour Solid(1S,2R)-Globalagliatin
CAS:(1S,2R)-Globalagliatin is a highly potent glucokinase (GK) activator for the study of type 2 diabetes.Fórmula:C28H37N3O3S3Pureza:99.09% - 99.17%Forma y color:SoildPeso molecular:559.81PF-04991532
CAS:PF-04991532 is a hepatoselective glucokinase activator that reduces plasma glucose and AMP concentrations in the Goto-Kakizaki rat model.Fórmula:C18H19F3N4O3Pureza:99.99%Forma y color:SolidPeso molecular:396.36Cadisegliatin
CAS:Cadisegliatin (TTP-399) may activate liver GK to lower blood sugar in type 2 diabetes studies.Fórmula:C21H33N3O4S2Forma y color:SolidPeso molecular:455.63Anti-Glucokinase Antibody (3U461)
Anti-Glucokinase Antibody (3U461) is a Rabbit antibody targeting Glucokinase. Anti-Glucokinase Antibody (3U461) can be used in ELISA.Forma y color:Odour Liquid5MPN
CAS:5MPN is a PFKFB4 inhibitor that inhibits the F6P binding site and suppresses the proliferation of myeloma cells.Fórmula:C15H19N3O4Pureza:98.92% - 99.69%Forma y color:SolidPeso molecular:305.33Anti-Glucokinase Antibody (5Q209)
Anti-Glucokinase Antibody (5Q209) is a Mouse antibody targeting Glucokinase. Anti-Glucokinase Antibody (5Q209) can be used in ELISA.Forma y color:Odour LiquidHex
CAS:Hex is a potent inhibitor of enolase, exhibiting inhibitory activity with Ki values of 74.4 nM and 269.4 nM against ENO2 and ENO1, respectively.Fórmula:C5H10NO5PForma y color:SolidPeso molecular:195.11Glucokinase Protein, Human, Recombinant
Glucokinase belongs to the bacterial glucokinase family.Forma y color:Lyophilized PowderPeso molecular:52.2 kDa (predicted); 52.2 kDa (reducing conditions)
