Glucoquinasa
La glucocinasa (GK) es una enzima que cataliza la fosforilación de la glucosa a glucosa-6-fosfato, un paso crítico en la glucólisis. La GK se expresa predominantemente en el hígado y el páncreas, donde desempeña un papel clave en la regulación de los niveles de glucosa en sangre. Los inhibidores de GK son de interés en el estudio de trastornos metabólicos como la diabetes, ya que pueden modular el metabolismo de la glucosa y la secreción de insulina. En CymitQuimica, ofrecemos inhibidores de glucocinasa para apoyar su investigación en diabetes, metabolismo y desarrollo terapéutico.
Se han encontrado 53 productos de "Glucoquinasa"
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Dorzagliatin
CAS:<p>Dorzagliatin (HMS5552) is a dual-acting glucokinase (GK) activator. It also improves glycaemic control and pancreatic β-cell function in type 2 diabetes.</p>Fórmula:C22H27ClN4O5Pureza:98.67% - 99.45%Forma y color:SolidPeso molecular:462.93MitoPQ
CAS:<p>MitoPQ (MitoParaquat) inhibits insulin-stimulated glucose uptake and plasma membrane translocation in myotubes and can be used to study oxidative stress.</p>Fórmula:C39H46I3N2PPureza:99.91% - ≥98%Forma y color:SolidPeso molecular:954.48WAY-640509
CAS:<p>WAY-640509 is a glucocerebrosidase inhibitor.</p>Fórmula:C25H23N5O4SPureza:99.36%Forma y color:SolidPeso molecular:489.55MK-0941 free base
CAS:<p>MK-0941: an oral glucokinase activator for type 2 diabetes with potent glucose-lowering effects.</p>Fórmula:C21H24N4O6SPureza:98.75%Forma y color:SolidPeso molecular:460.5Oxfendazole
CAS:<p>Oxfendazole (RS-8858), a broad spectrum benzimidazole anthelmintic, protects livestock against roundworm, strongyles and pinworms.</p>Fórmula:C15H13N3O3SPureza:98.99% - 99.17%Forma y color:White To Yellowish PowderPeso molecular:315.35KAN0438757
CAS:<p>KAN0438757 is a selective and potent inhibitor of the metabolic kinase PFKFB3 with an IC50 of 0.19 μM.</p>Fórmula:C21H18FNO7SPureza:99.34%Forma y color:SolidPeso molecular:447.43ADP-specific glucokinase
CAS:<p>ADP-specific glucokinase, expressed in thermophilic archaea, is an ADP-specific enzyme that catalyzes the conversion of glucose to glucose-6-phosphate, thereby facilitating glycolysis. This enzyme can activate T cells and enhance the phagocytic activity of macrophages. It is used in research related to metabolic disorders, neurological diseases, and tumors.</p>Forma y color:Solid(1S,2R)-Globalagliatin
CAS:<p>(1S,2R)-Globalagliatin is a highly potent glucokinase (GK) activator for the study of type 2 diabetes.</p>Fórmula:C28H37N3O3S3Pureza:99.09% - >99.99%Forma y color:SoildPeso molecular:559.81ML266
CAS:<p>ML266: GCase chaperone, non-inhibiting, IC50=2.5 µM, aids mutant protein transport, may help in Gaucher disease study.</p>Fórmula:C24H22BrN3O4Pureza:99.58%Forma y color:SolidPeso molecular:496.35ML251
CAS:<p>ML251, potent inhibitor, targets T. brucei PFK (IC50=0.37μM) & T. cruzi PFK (IC50=0.13μM), aids parasite research.</p>Fórmula:C17H13Cl2N3O4SPureza:99.87%Forma y color:SolidPeso molecular:426.27AP-III-a4 hydrochloride
CAS:<p>AP-III-a4 hydrochloride (ENOblock hydrochloride) is a direct enolase (enolase) inhibitor that inhibit metastasis and affect glucose homeostasis.</p>Fórmula:C31H44ClFN8O3Pureza:98%Forma y color:SolidPeso molecular:631.18Glucokinase Protein, Human, Recombinant
<p>Glucokinase belongs to the bacterial glucokinase family.</p>Forma y color:Lyophilized PowderPeso molecular:52.2 kDa (predicted); 52.2 kDa (reducing conditions)Cadisegliatin
CAS:<p>Cadisegliatin (TTP-399) may activate liver GK to lower blood sugar in type 2 diabetes studies.</p>Fórmula:C21H33N3O4S2Forma y color:SolidPeso molecular:455.63Anti-Glucokinase Antibody (5Q209)
<p>Anti-Glucokinase Antibody (5Q209) is a Mouse antibody targeting Glucokinase. Anti-Glucokinase Antibody (5Q209) can be used in ELISA.</p>Forma y color:Odour LiquidAnti-Glucokinase Antibody (3U461)
<p>Anti-Glucokinase Antibody (3U461) is a Rabbit antibody targeting Glucokinase. Anti-Glucokinase Antibody (3U461) can be used in ELISA.</p>Forma y color:Odour Liquid5MPN
CAS:<p>5MPN is a PFKFB4 inhibitor that inhibits the F6P binding site and suppresses the proliferation of myeloma cells.</p>Fórmula:C15H19N3O4Pureza:98.92% - 99.69%Forma y color:SolidPeso molecular:305.33PF-04991532
CAS:<p>PF-04991532 is a hepatoselective glucokinase activator that reduces plasma glucose and AMP concentrations in the Goto-Kakizaki rat model.</p>Fórmula:C18H19F3N4O3Pureza:99.99%Forma y color:SolidPeso molecular:396.36PFK-015
CAS:<p>PFK-015 (PFK15) is an effective inhibitor of PFKFB3 (IC50: 110 nM) and inhibits PFKFB3 activity in Y cells (IC50: 20 nM).</p>Fórmula:C17H12N2OPureza:99.7% - 99.85%Forma y color:SolidPeso molecular:260.29Globalagliatin
CAS:<p>Globalagliatin (LY2608204) has been used in trials studying the treatment of Diabetes Mellitus, Type 2.</p>Fórmula:C28H37N3O3S3Pureza:98% - 99.49%Forma y color:SolidPeso molecular:559.81(E)-3PO
CAS:<p>(E)-3PO is a PFKFB3 (6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase) inhibitor.</p>Fórmula:C13H10N2OPureza:98.8% - 98.92%Forma y color:SolidPeso molecular:210.23
