Factor Xa
El factor Xa es una enzima crucial en la cascada de coagulación que convierte la protrombina en trombina, lo que lleva a la formación de coágulos sanguíneos. La inhibición del factor Xa es una estrategia terapéutica ampliamente utilizada para prevenir y tratar los trastornos tromboembólicos, como la trombosis venosa profunda, la embolia pulmonar y el accidente cerebrovascular. En CymitQuimica, ofrecemos inhibidores del factor Xa para apoyar su investigación en hematología, salud cardiovascular y terapia anticoagulante.
Se han encontrado 85 productos de "Factor Xa"
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Garadacimab
CAS:<p>Garadacimab (CSL312) is a human IgG4 antibody against FXIIa, used to research hereditary angioedema.</p>Pureza:SDS-PAGE:95% SEC-HPLC:99.99%Forma y color:LiquidPeso molecular:146.5 kDaRivaroxaban
CAS:Rivaroxaban (BAY 59-7939) is an oral, direct factor Xa inhibitor with anticoagulant properties, interfering with thrombin formation.Fórmula:C19H18ClN3O5SPureza:99.93% - >99.99%Forma y color:SolidPeso molecular:435.88Ciraparantag acetate
CAS:Ciraparantag acetate reverses anticoagulation, binding heparins and DOACs noncovalently.Fórmula:C24H52N12O4Pureza:99.65%Forma y color:SolidPeso molecular:572.75Letaxaban
CAS:Letaxaban (TAK-442) is a small molecule Xa factor inhibitor that can be used to study polar coronary syndromes and thrombotic blockages.Fórmula:C22H26ClN3O5SPureza:99.13% - 99.87%Forma y color:SolidPeso molecular:479.985-R-Rivaroxaban
CAS:<p>5-R-Rivaroxaban is the (R)-enantiomer of Rivaroxaban, a potent FXa inhibitor with IC50 0.7 nM and Ki 0.4 nM.</p>Fórmula:C19H18ClN3O5SPureza:99.75%Forma y color:SolidPeso molecular:435.88Osocimab
CAS:<p>Osocimab (BAY 1213790) is a strong FXIa inhibitor, Ki 2.4 nM, EC50 0.2 nM, and reduces thrombosis in research.</p>Pureza:> 95% - > 95%Forma y color:LiquidPeso molecular:144.46 kDa2-Methoxyphenothiazine
CAS:2-Methoxy Phenothiazine is light yellow or light gray solid.Fórmula:C13H11NOSPureza:99.28%Forma y color:Orange Yellow Crystal PowderPeso molecular:229.3Gabexate mesylate
CAS:Gabexate mesylate (FOY) inhibits thrombin, plasmin, kallikrein; used for pancreatitis, DIC, hemodialysis anticoagulant.Fórmula:C17H27N3O7SPureza:99.2% - 99.64%Forma y color:White CrystalPeso molecular:417.48Asundexian
CAS:Asundexian (BAY-2433334) is a potent and orally active inhibitor of the coagulation factor FXIa that directly and reversibly binds to the active site of FXIa,Fórmula:C26H21ClF4N6O4Pureza:99.89% - 99.90%Forma y color:SolidPeso molecular:592.93Rat Factor Xa
<p>RatFactor Xa is derived from the activation of purified Rat Factor X using Russells' Viper Venom. Following activation, Russells' Viper Venom is removed.</p>Forma y color:Odour SolidCanine Factor Xa
<p>CanineFactor Xa is derived from purified Canine Factor X through activation by Russell's Viper Venom, after which the venom is removed.</p>Forma y color:Odour SolidFXIIa-IN-4
<p>FXIIa-IN-4 (compound 22) is a potent and selective human FXIIa inhibitor, exhibiting IC50 values of 0.032 μM for FXIIa, 0.30 μM for thrombin, and >50 μM for FXIa. It is utilized in anticoagulant research.</p>Fórmula:C11H9FN4O3Peso molecular:264.06587Concizumab
CAS:Concizumab is an anti-TFPI monoclonal antibody (IgG4 type) that selectively binds to the Kunitz protease inhibitor (KPI) 2 domain of TFPI, thereby blocking thePureza:> 95%Forma y color:LiquidPeso molecular:145.76 kDaChromozym PK
CAS:Chromozym PK is a chromogenic substrate for factor XII assay.Fórmula:C33H38N8O6Forma y color:SolidPeso molecular:642.70D-Leu-Pro-Arg-Rh110-D-Pro acetate
D-Leu-Pro-Arg-Rh110-D-Pro acetate is a substrate for Factor XaI (FXIa) with binding affinity. This compound is formed by linking Rhodamine 110 to a peptide chain via a cleavable bond. The cleavage of this bond enhances the intensity of the fluorophore. D-Leu-Pro-Arg-Rh110-D-Pro acetate can be used to detect FXIa activity.Fórmula:C42H51N9O7·xC2H4O2CH3OCO-D-CHA-Gly-Arg-pNA acetate
CAS:CH3OCO-D-CHA-Gly-Arg-pNA acetate serves as a chromogenic substrate for Factor Xa, as documented in sources [1] [2].Fórmula:C27H42N8O9Pureza:98%Forma y color:SolidPeso molecular:622.67O-Desmethyl apixaban sulfate sodium
O-Desmethyl apixaban sulfate sodium inhibits factor X (FXa) with a Ki of 58 μM,and is a major circulating metabolite of Apixaban in humans.Fórmula:C24H22N5NaO7SPureza:98%Forma y color:SolidPeso molecular:547.52Naroparcil
CAS:Naroparcil, an oral thioglycoside, has antithrombotic properties and alters thrombin complex formation.Fórmula:C19H17NO4S2Pureza:99.88% - 99.99%Forma y color:SolidPeso molecular:387.47FXIIa-IN-3
FXIIa-IN-3 (Compound 8) is an effective and selective inhibitor of Factor XIIa (FXIIa), with an IC50 of 0.045 μM. It demonstrates significant selectivity over related serine proteases, including FXIa, FXa, and FIXa. FXIIa-IN-3 is suitable for research in thromboembolic diseases.Fórmula:C14H16N4O6Peso molecular:336.10698Boc-Ile-Glu-Gly-Arg-AMC
CAS:<p>Boc-IEGR-AMC: fluorogenic substrate for factor Xa and Halocynthia roretzi acrosin.</p>Fórmula:C34H50N8O10Pureza:98%Forma y color:White PowderPeso molecular:730.81Lofacimig
Lofacimig is a bispecific antibody of VH-VH-G1(h-CH2-CH3) dimer type that targets FXI/PTA.Forma y color:Odour LiquidPorcine Factor Xa
CAS:PorcineFactor Xa is obtained by activating purified Porcine Factor X using Russells' Viper Venom, after which the venom is removed.Forma y color:SolidRabbit Factor Xa
RabbitFactor Xa is produced from purified Rabbit Factor X through activation by Russells' Viper Venom, followed by the removal of the venom.Forma y color:Odour SolidMethoxycarbonyl-D-Nle-Gly-Arg-pNA
CAS:Methoxycarbonyl-D-Nle-Gly-Arg-pNA is a synthetic trypsin substrate utilized for coagulation factors IXa (FIXa) and Xa (FXa), as evidenced by studies [1] [2] [3Fórmula:C22H34N8O7Forma y color:SolidPeso molecular:522.55D-Pro-Phe-Arg-Chloromethylketone
CAS:D-Pro-Phe-Arg-Chloromethylketone, an inhibitor of coagulation factor XII and plasma kallikrein, is significant in the regulation of thrombosis and inflammationFórmula:C21H31ClN6O3Pureza:98%Forma y color:SolidPeso molecular:450.96FXIa-IN-15
CAS:<p>FXIa-IN-15 (Compound (S)-10h) is an inhibitor of factor XIa (FXIa) and plasma kallikrein (PKa) with IC50 values of 0.38 nM and 59.2 nM, respectively. It exhibits anticoagulant properties by prolonging the 50% activated partial thromboplastin time (aPTT) with an EC1.5X of 0.55 μM.</p>Fórmula:C32H23ClF3N7O4Forma y color:SolidPeso molecular:662.02FXIIa-IN-1 HCl
CAS:FXIIa-IN-1 HCl is a selective inhibitor of Factor XIIa,and can be used to study thrombosis and inflammation induced by artificial surfaces.Fórmula:C21H17ClN2O6Pureza:99.61%Forma y color:SoildPeso molecular:428.82Edoxaban Isomer
CAS:Edoxaban Isomer is an impurity of Edoxaban, which is a novel inhibitor of factor Xa.Fórmula:C24H30ClN7O4SForma y color:SolidPeso molecular:548.06cMCoFx1
CAS:cMCoFx1 is an effective and selective FXIIa cyclic peptide inhibitor. It exhibits high binding affinity for FXIIa (KD: 900 pM) and potent inhibitory activity (Ki: 370 pM). cMCoFx1 effectively suppresses the intrinsic coagulation pathway, demonstrates high stability in serum, and shows no cytotoxicity.Fórmula:C146H232N52O44S6Forma y color:SolidPeso molecular:3612.12Edoxaban impurity 6
CAS:<p>Edoxaban impurity 6 is a byproduct of the anticoagulant Edoxaban, a potent oral factor Xa inhibitor with Kis of 0.561 nM. Used to prevent stroke.</p>Fórmula:C16H22ClN5O3Forma y color:SolidPeso molecular:367.83Ethyl 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate
CAS:<p>Ethyl 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl) compound inhibits coagulation factor Xa, useful for thrombotic conditions study.</p>Fórmula:C27H28N4O5Pureza:99.5%Forma y color:SolidPeso molecular:488.54Betrixaban-d6
CAS:Betrixaban D6 is a deuterium-labeled Betrixaban. Betrixaban is a selective and orally efficacious FXa inhibitor.Fórmula:C23H22ClN5O3Pureza:98%Forma y color:SolidPeso molecular:457.95Apixaban 13C,d3
CAS:Apixaban 13C,d3 is a deuterium labeling of Apixaban for isotopic tracing. Apixaban 13C,d3 is a selective inhibitor of coagulation factor XaFórmula:C25H25N5O4Pureza:98%Forma y color:SolidPeso molecular:463.51Darexaban
CAS:<p>Darexaban (YM-150) selectively inhibits Factor Xa, reducing clotting and risk of heart/stroke events.</p>Fórmula:C27H30N4O4Pureza:98.33%Forma y color:SolidPeso molecular:474.55Enoxaparin sodium
CAS:Enoxaparin, a low-weight heparin approved by FDA for STEMI, enhances antithrombin and prevents clotting by inhibiting factors XIa, IXa, Xa, IIa.Fórmula:C42H59N3Na4O35S2Pureza:98%Forma y color:SolidPeso molecular:1322Edoxaban Tosylate Monohydrate
CAS:<p>Edoxaban(DU-176) is an oral factor Xa (FXa) inhibitor in clinical development for stroke prevention.</p>Fórmula:C31H40ClN7O8S2Pureza:99.86% - 99.91%Forma y color:SolidPeso molecular:738.27Apixaban
CAS:Apixaban (BMS-562247-01) is an orally active inhibitor of coagulation factor Xa with anticoagulant activity.Fórmula:C25H25N5O4Pureza:99.73% - 99.93%Forma y color:SolidPeso molecular:459.5Edoxaban hydrochloride
CAS:Edoxaban (DU-176b) HCl: Oral, selective Factor Xa inhibitor, Ki 0.561 nM; prevents thromboembolic disease.Fórmula:C24H31Cl2N7O4SForma y color:SolidPeso molecular:584.52Fondaparinux sodium
CAS:<p>Fondaparinux sodium (SR-90107A) is an antithrombin-dependent factor Xa inhibitor with antithrombotic activity.</p>Fórmula:C31H43N3Na10O49S8Pureza:98% - >99.99%Forma y color:SolidPeso molecular:1728.084-Chlorophenylurea
CAS:4-Chlorophenylurea (NSC-12971) is a novel orally bioavailable inhibitor of factor Xa.Fórmula:C7H7ClN2OPureza:98.87%Forma y color:White Granular / PrillPeso molecular:170.6Heparin sodium salt
CAS:Heparin sodium, a sulfated glycosaminoglycan, acts as an anticoagulant and inhibits exosome-cell interactions.Fórmula:C26H42N2NaO37S5Pureza:98%Forma y color:SolidPeso molecular:1157.89Benzamidine hydrochloride
CAS:<p>Benzamidine hydrochloride (Benzamidine HCl) is a reversible inhibitor of serine proteases, including trypsin, plasmin, and thrombin.</p>Fórmula:C7H9ClN2Pureza:99.25% - 99.97%Forma y color:White To Off-White PowderPeso molecular:156.61Betrixaban hydrochloride(330942-05-7(free base))
Betrixaban hydrochloride(330942-05-7(free base)) (PRT054021 hydrochloride) is a potent, selective, and orally efficacious factor Xa (fXa) inhibitor (IC50: 1.5Fórmula:C23H23Cl2N5O3Pureza:99.54%Forma y color:SolidPeso molecular:488.36BISMUTH SUBGALLATE
CAS:<p>Bismuth subgallate (Dermatol Puder) is an astringent and antiseptic and is applied to skin diseases such as eczema.</p>Fórmula:C7H5BiO6Pureza:98.7%Forma y color:White To Yellow CrystalsPeso molecular:394.09Abelacimab
CAS:NI-0801 (Anti-CXCL10 / IP-1) is a CHO-expressed humanized monoclonal antibody targeting CXCL10/IP-10 for the study of vitiligo and biliary cirrhosis.Pureza:94.9% (SDS-PAGE); 99.1% (SEC-HPLC) - 94.9% (SDS-PAGE); 99.1% (SEC-HPLC)Forma y color:LiquidEdoxaban-d6
CAS:Edoxaban-d6 is a deuterated compound of Edoxaban. Edoxaban has a CAS number of 480449-70-5. Edoxaban(DU-176) is an oral factor Xa (FXa) inhibitor in clinical development for stroke prevention.Fórmula:C24H24D6ClN7O4SForma y color:SolidPeso molecular:554.09Betrixaban maleate
CAS:<p>"Betrixaban, a non-vitamin K anticoagulant by Portola, inhibits factor Xa with low hERG affinity, preventing VTE in at-risk adults."</p>Fórmula:C27H26ClN5O7Pureza:99.46% - 99.86%Forma y color:SolidPeso molecular:567.98Rivaroxaban-d4
CAS:<p>Rivaroxaban-d4 is a deuterated marker of Rivaroxaban for isotopic tracing.BAY 59-7939 is a potent and selective direct inhibitor of coagulation factor Xa (FXa.</p>Fórmula:C19H18ClN3O5SPureza:98%Forma y color:SolidPeso molecular:439.91Betrixaban
CAS:Betrixaban is a non-VKORC1 anticoagulant targeting factor Xa, with low hERG affinity, used to prevent VTE in adults with mobility issues.Fórmula:C23H22ClN5O3Pureza:99.33%Forma y color:SolidPeso molecular:451.91Milvexian
CAS:Milvexian (BMS-986177) is an oral antithrombotic, reversibly inhibiting human/rabbit FXIa with K i of 0.11/0.38 nM.Fórmula:C28H23Cl2F2N9O2Forma y color:SolidPeso molecular:626.45Eribaxaban
CAS:Eribaxaban (PD348292) is an orally available factor Xa inhibitor for the prevention and treatment of venous thromboembolism.Fórmula:C24H22ClFN4O4Pureza:98.99% - 99.13%Forma y color:SolidPeso molecular:484.91YM-75466
CAS:YM-75466 is a factor Xa inhibitor reducing TAT in plasma dose-dependently without prolonging coagulation.Fórmula:C28H35N5O8S2Forma y color:SolidPeso molecular:633.74Ciraparantag TFA
CAS:Ciraparantag TFA reverses anticoagulants by inhibiting thrombin and factor Xa.Fórmula:C26H50F6N12O6Pureza:98%Forma y color:SolidPeso molecular:740.74BMS 740808
CAS:BMS-740808 is a highly effective and selective factor X inhibitor.Fórmula:C31H27F3N6O3Forma y color:SolidPeso molecular:588.58Milvexian TFA
CAS:Milvexian (BMS-986177/JNJ-70033093) is a factor XIa inhibitor with Ki=44 nM for kallikrein, Ki=35 nM for chymotrypsin, 32% bioavailability.Fórmula:C30H26Cl2F5N9O4Forma y color:SolidPeso molecular:742.49Ciraparantag
CAS:Ciraparantag inhibits thrombin, factor Xa, and reverses various anticoagulants.Fórmula:C22H48N12O2Pureza:98%Forma y color:SolidPeso molecular:512.7Darexaban glucuronide
CAS:Darexaban glucuronide is the major component in plasma after oral administration of darexaban to humans. Darexaban (YM150) is a direct inhibitor of factor Xa.Fórmula:C33H38N4O10Forma y color:SolidPeso molecular:650.68Tanogitran
CAS:Tanogitran, a coagulation factor Xa inhibitor, is used potentially for the treatment of septic shock.Fórmula:C25H31N7O3Pureza:98%Forma y color:SolidPeso molecular:477.56DPC-423
CAS:DPC-423 is a factor Xa inhibitor potentially for the treatment of thrombosis.Fórmula:C25H21ClF4N4O3SPureza:98%Forma y color:SolidPeso molecular:568.97Razaxaban hydrochloride
CAS:Razaxaban hydrochloride is a highly potent, selective and orally active inhibitor of factor Xa(Ki of 0.19 nM),has strongly antithrombotic activity.Fórmula:C24H21ClF4N8O2Pureza:98%Forma y color:SolidPeso molecular:564.92Otamixaban
CAS:Otamixaban (FXV673) is a selective and highly effective Xa inhibitor that inhibits the generation of thrombin and can be used to study acute coronary syndrome.Fórmula:C25H26N4O4Pureza:98.08%Forma y color:SolidPeso molecular:446.5Pegnivacogin
CAS:Pegnivacogin is a coagulation factor IXa RNA aptamer inhibitor.Fórmula:C20H40N3O11PPureza:98%Forma y color:SolidPeso molecular:529.52Edoxaban
CAS:Edoxaban: potent, selective FXa inhibitor; Ki 0.561 nM. Used as an oral anticoagulant for stroke prevention, also inhibits thrombin and FIXa.Fórmula:C24H30ClN7O4SPureza:97.67% - 99.71%Forma y color:SolidPeso molecular:548.06Fidexaban
CAS:<p>Fidexaban (CI1031) is a novel, potent, selective and orally active factor Xa inhibitor that has demonstrated antithrombotic activity in a variety of assays</p>Fórmula:C25H24F2N6O5Pureza:98.64% - 99.43%Forma y color:SolidPeso molecular:526.49LY 517717
CAS:LY 517717 is an orally active inhibitor of coagulation factor Xa with antithrombotic activity for the study of venous thromboembolism (VTE).Fórmula:C27H33N5O2Pureza:99.77% - 99.88%Forma y color:SolidPeso molecular:459.58Zifaxaban
CAS:Zifaxaban (TY-602) is an oral selective factor Xa inhibitor with an IC50 of 11.1 nM, highly specific over other serine proteases, used in thrombosis studies.Fórmula:C20H16ClN3O4SPureza:97.46% - 99.82%Forma y color:SolidPeso molecular:429.88BI-11634
CAS:BI-11634 is a factor Xa inhibitor.Fórmula:C22H23ClN4NaO4Pureza:98%Forma y color:SolidPeso molecular:465.89BMS-654457
CAS:BMS-654457 is a small-molecule, reversible inhibitor of factor XIa (FXIa; Kis: 0.2 and 0.42 nM for human and rabbit FXIa).Fórmula:C36H37N5O4Pureza:98%Forma y color:SolidPeso molecular:603.71Frunexian
CAS:Frunexian (EP-7041) is a selective and potent inhibitor of coagulation factor XI/activated factor XI, specifically targeting XIa.Fórmula:C19H26N4O4Pureza:98%Forma y color:SolidPeso molecular:374.43BMS-262084
CAS:BMS-262084 is a potent selective β-lactam trypsin inhibitor with therapeutic potential in the treatment of asthma.Fórmula:C18H31N7O5Forma y color:SolidPeso molecular:425.48FXIa-IN-1
CAS:FXIa-IN-1 is a potent β-lactam covalent heparin-derived factor XIa (fXIa) inhibitor.Fórmula:C20H19F3N4O5Pureza:98%Forma y color:SolidPeso molecular:452.38AS1468240
CAS:AS1468240 is a factor Xa inhibitor. It has significant oral anticoagulant activity.Fórmula:C25H25Cl2N5O3Forma y color:SolidPeso molecular:514.4FXa-IN-1
CAS:FXa-IN-1, an FXa blocker: IC50=3 nM, Ki=0.7 nM, orally available, long half-life, for thrombosis research.Fórmula:C24H18F5N5OForma y color:SolidPeso molecular:487.42FXIa-IN-7
CAS:FXIa-IN-7 is an orally available, selective and potent inhibitor of factor XIa for the study of thrombophilia.Fórmula:C28H28N2O4Pureza:98.55%Forma y color:SolidPeso molecular:456.53BMS-962212
CAS:BMS-962212: reversible, selective FXIa blocker, well-tolerated, quick PD effect, rapid clearance, alters clotting time/activity.Fórmula:C32H28ClFN8O5Pureza:98%Forma y color:SolidPeso molecular:659.07Dechloro Rivaroxaban
CAS:Dechloro Rivaroxaban is a Factor Xa inhibitor that inhibits free FXa and plasminogen and fibrin-associated FXa activity in humans.Fórmula:C19H19N3O5SPureza:98.63%Forma y color:SolidPeso molecular:401.44FXIa-IN-8
FXIa-IN-8: potent FXIa blocker (IC50: 14.2 nM), anti-thrombotic, low bleeding/toxicity risk.Forma y color:SolidFXIa-IN-10
FXIa-IN-10 is a potent, orally bioavailable inhibitor of Activator XI (FXIa) (Ki: 0.17 nM).Fórmula:C23H18Cl2F3N9O2Forma y color:SolidPeso molecular:580.35FXIa-IN-6
CAS:FXIa-IN-6: Potent, selective FXIa inhibitor (Ki=0.3 nM); strong PK with high oral bioavailability, low clearance preclinically.Fórmula:C31H29ClF2N4O4Forma y color:SolidPeso molecular:595.04FXIa-6f
CAS:<p>FXIa-6f is a high affinity, orally bioavailable macrocyclic FXIa inhibitor with antithrombotic activity in preclinical species</p>Fórmula:C31H29ClF2N4O4Forma y color:SolidPeso molecular:595.04DX-9065A HCl hydrate
CAS:<p>DX-9065a: Competitive fXa/prothrombinase inhibitor; blocks proinflammatory events; Ki ~10-20 nM.</p>Fórmula:C26H39ClN4O8Pureza:98%Forma y color:SolidPeso molecular:571.06RWJ-445167
CAS:RWJ-445167 is a thrombin and factor Xa dual inhibitor(Ki of 4.0 nM and 230 nM, respectively), with potent antithrombotic activity.Fórmula:C18H24N6O5SPureza:98%Forma y color:SolidPeso molecular:436.49FXIa-IN-9
CAS:FXIa-IN-9, a potent FXIa inhibitor (K i : human 0.17 nM, rabbit 0.5 nM), forms hydrogen bonds and has anticoagulant properties.Fórmula:C23H18Cl2F3N9O2Forma y color:SolidPeso molecular:580.35BAY 3389934
CAS:BAY 3389934 is a dual inhibitor of factor IIa (factor IIa) and factor Xa (factor Xa), providing anticoagulant and organ-protective effects. It alleviates coagulopathy and organ dysfunction in baboon models of Staphylococcus aureus sepsis.Fórmula:C26H30ClN5O7S2Forma y color:SolidPeso molecular:624.1295-Chlorothiophene-2-carboxylic acid
CAS:5-Chlorothiophene-2-carboxylic acid [catalog number: T66447, CAS number: 24065-33-6] is a valuable organic compound for life sciences research.Fórmula:C5H3ClO2SForma y color:SolidPeso molecular:162.59
