PPAR
Los receptores activados por proliferadores de peroxisomas (PPARs) son un grupo de proteínas receptoras nucleares que funcionan como factores de transcripción regulando la expresión de genes involucrados en el metabolismo, particularmente en el almacenamiento de ácidos grasos y el metabolismo de la glucosa. Los inhibidores de PPAR son herramientas importantes para estudiar trastornos metabólicos como la diabetes, la obesidad y las enfermedades cardiovasculares. Estos inhibidores pueden modular el metabolismo de los lípidos, la sensibilidad a la insulina y la inflamación, lo que los convierte en valiosos en la investigación terapéutica. En CymitQuimica, ofrecemos una gama de inhibidores de PPAR para apoyar su investigación en enfermedades metabólicas, endocrinología y desarrollo de fármacos.
Se han encontrado 169 productos de "PPAR"
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Licarin B
CAS:1.(-)-Licarin B (Licarine B) has anti-mycobacterial activity.Fórmula:C20H20O4Pureza:99.82% - ≥95%Forma y color:SolidPeso molecular:324.37Troglitazone
CAS:Troglitazone (Romglizone) is a PPARγ agonist with anti-inflammatory and anti-tumor activity.Fórmula:C24H27NO5SPureza:98% - 99.8%Forma y color:Yellow SolidPeso molecular:441.54Eupatilin
CAS:<p>Eupatilin (NSC-122413), a flavone derived from Artemisia princepsPampanini, is a PPARα agonist, with pharmacological activity.</p>Fórmula:C18H16O7Pureza:98.53% - 99%Forma y color:SolidPeso molecular:344.32DG172 dihydrochloride
CAS:<p>DG172 dihydrochloride (DG-172 dihydrochloride) is an antagonist of PPARβ/δ(IC50 : 27 nM).</p>Fórmula:C20H22BrCl2N3Pureza:99.87%Forma y color:SolidPeso molecular:455.2Tetradecylthioacetic acid
CAS:<p>Synthetic fatty acid TTA has β-sulfur, resists β-oxidation, and activates PPARs, especially PPARα.</p>Fórmula:C16H32O2SPureza:99.93%Forma y color:SolidPeso molecular:288.49T0070907
CAS:<p>T0070907(IC50=1 nM) , an effective and specific PPARγ inhibitor, with the >800-fold selectivity over PPARα and PPARδ.</p>Fórmula:C12H8ClN3O3Pureza:98.25% - 99.98%Forma y color:SolidPeso molecular:277.66Seladelpar
CAS:Seladelpar (MBX 8025) has been used in trials studying the treatment of Hyperlipidemia.Fórmula:C21H23F3O5SPureza:99.18% - 99.41%Forma y color:SolidPeso molecular:444.46Rosiglitazone
CAS:<p>Rosiglitazone (BRL49653) is a PPARγ agonist, TRPC5 activator, and TRPM3 inhibitor with oral activity.</p>Fórmula:C18H19N3O3SPureza:98.61% - 99.87%Forma y color:White To Off-White Crystalline PowderPeso molecular:357.43Angeloylgomisin H
CAS:Angeloylgomisin H shows moderate cytotoxic activities with IC50 values ranging from 100 to 200 ug/mL against MCF7, HEK293 and CAL27 cell lines.Fórmula:C28H36O8Pureza:99.84% - 99.95%Forma y color:SolidPeso molecular:500.58GW9662
CAS:GW9662 (TIMTEC-BB SBB006523) is a PPARγ antagonist (IC50=3.3 nM) with selectivity. GW9662 has anti-tumor effect. High-Quality, Low-Cost!Fórmula:C13H9ClN2O3Pureza:98% - 99.98%Forma y color:Off-White SolidPeso molecular:276.68SR1664
CAS:<p>SR1664 is a potent and selective PPARγ inhibitor with potential antidiabetic activity.</p>Fórmula:C33H29N3O5Pureza:98.02%Forma y color:SolidPeso molecular:547.6FH535
CAS:FH535, a Wnt/β-catenin signaling and PPAR inhibitor, exhibits anti-tumor activities.Fórmula:C13H10Cl2N2O4SPureza:98.25% - 99.5%Forma y color:SolidPeso molecular:361.2Icariin
CAS:Icariin (Ieariline) is a flavonol glycoside that inhibits PDE5 and PDE4 activity and is a PPARα activator. Cost-effective and quality-assured.Fórmula:C33H40O15Pureza:97.82% - 98.3%Forma y color:SolidPeso molecular:676.66GW6471
CAS:GW6471 is an antagonist of PPARα. GW6471 enhances the binding affinity of the PPAR α ligand-binding domain to the co-repressor proteins SMRT and NCoR.Fórmula:C35H36F3N3O4Pureza:98.23% - 99.55%Forma y color:SolidPeso molecular:619.67Palmitelaidic Acid
CAS:Palmitelaidic Acid (trans-Palmitoleic acid) is one of the most abundant fatty acids in serum and tissue.Fórmula:C16H30O2Pureza:99.76%Forma y color:SolidPeso molecular:254.41NSC-87877 disodium
CAS:NSC-87877 disodium (NSC87877) is a cell-permeable inhibitor of both SHP-1 and SHP-2. NSC-87877 also inhibits EGF-induced Erk1/2 activation in HEK293 cells.Fórmula:C19H13N3O7S2·2NaPureza:97.89%Forma y color:SolidPeso molecular:503.42Glabrone
CAS:<p>Glabrone shows antiviral activity against influenza virus.</p>Fórmula:C20H16O5Pureza:99.08% - 99.55%Forma y color:SolidPeso molecular:336.34Tesaglitazar
CAS:<p>Tesaglitazar is a potent and selective peroxide PPARα / γ receptor dual agonist with a more potent affinity for PPARγ than PPARα, The EC50 values for rat PPARα</p>Fórmula:C20H24O7SPureza:99.95%Forma y color:SolidPeso molecular:408.47THR-0921
CAS:THR-0921 (CLX-0921) is a peroxisome proliferator-activated receptor (PPAR) agonist that can be used to study cardiovascular and metabolic diseases.Fórmula:C28H25NO7SPureza:100% - 99.83%Forma y color:SolidPeso molecular:519.5713-Oxo-9E,11E-octadecadienoic acid
CAS:<p>13-Oxo-9E,11E-octadecadienoic acid from tomato juice, an isomer of 9-oxo-ODA, activates PPARα and lowers triglycerides in diabetic mice.</p>Fórmula:C18H30O3Pureza:98%Forma y color:SolidPeso molecular:294.43
