PPAR
Los receptores activados por proliferadores de peroxisomas (PPARs) son un grupo de proteínas receptoras nucleares que funcionan como factores de transcripción regulando la expresión de genes involucrados en el metabolismo, particularmente en el almacenamiento de ácidos grasos y el metabolismo de la glucosa. Los inhibidores de PPAR son herramientas importantes para estudiar trastornos metabólicos como la diabetes, la obesidad y las enfermedades cardiovasculares. Estos inhibidores pueden modular el metabolismo de los lípidos, la sensibilidad a la insulina y la inflamación, lo que los convierte en valiosos en la investigación terapéutica. En CymitQuimica, ofrecemos una gama de inhibidores de PPAR para apoyar su investigación en enfermedades metabólicas, endocrinología y desarrollo de fármacos.
Se han encontrado 179 productos para "PPAR".
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Choline Fenofibrate
CAS:Choline Fenofibrate (Trilipix) is a choline formulation of fenofibrate, a synthetic phenoxy-isobutyric acid derivate and prodrug with antihyperlipidemicFórmula:C22H28ClNO5Pureza:98.82%Forma y color:SolidPeso molecular:421.91E0924G
CAS:E0924G is an orally active PPARδ agonist with an EC50 of 2.82 μM. It enhances the upregulation of osteoprotegerin (OPG) expression, with an EC50 of 0.29 μM. E0924G reduces RANKL-induced osteoclast differentiation and inhibits F-actin ring formation in RAW264.7 macrophages. Additionally, E0924G modulates bone density and bone loss in models of ovariectomy (OVX) and age-related osteoporosis.Fórmula:C12H12N2O3Forma y color:SolidPeso molecular:232.24(±)-CBCQ
CAS:(±)-CBCQ, an oxidation product of cannabidiol, exhibits an EC50 value of 14.7 μM for the activation of peroxisome proliferator-activated receptor γ (PPAR-γ).Fórmula:C21H28O3Forma y color:SolidPeso molecular:328.45Prostaglandin A3
CAS:Prostaglandin A3 is a non-enzymatic dehydration product of prostaglandin E3 (PGE3). It demonstrates significant affinity for canine EP2 and EP4 receptors with IC50 values of 120 nM and 20 nM, respectively. For human PPARγ, Prostaglandin A3 has a Ki value of 188 μM.Fórmula:C20H28O4Peso molecular:332.43Fmoc-Leu-OH-D10
CAS:Fmoc-Leu-OH-D10 is a deuterated compound of Fmoc-Leu-OH. Fmoc-Leu-OH (T8638) has a CAS number of 35661-60-0. NPC 15199 is an anti-inflammatory agent.Fórmula:C21D10H13NO4Peso molecular:363.47Anti-obesity agent 1
Compound 4 (Anti-obesity agent 1) demonstrates potential for enhanced lipolysis, highlighting its anti-obesity characteristics.Fórmula:C21H22N2O6Forma y color:SolidPeso molecular:398.409PPARγ agonist 16
CAS:PPARγ agonist16 (Compound 4G) is a PPARγ agonist that competitively binds to the ligand-binding domain (LBD) of PPARγ with an IC50 of 1790 nM. It reduces ear swelling in mouse models and exhibits antihyperglycemic activity in mice with Streptozotocin-induced diabetes.Fórmula:C19H14BrNO4SForma y color:SolidPeso molecular:432.29Tesaglitazar
CAS:Tesaglitazar is a potent and selective peroxide PPARα / γ receptor dual agonist with a more potent affinity for PPARγ than PPARα, The EC50 values for rat PPARαFórmula:C20H24O7SPureza:99.95%Forma y color:SolidPeso molecular:408.47Ref: TM-T17044
1mg43,00€1mL*10mM (DMSO)92,00€5mg93,00€10mg130,00€25mg241,00€50mg405,00€100mg632,00€200mg875,00€Inolitazone dihydrochloride
CAS:Inolitazone dihydrochloride is an effective, high-affinity PPARγ agonist; its biological activity is dependent on PPARγ (IC50:0.8 nM) to inhibit cell growth.Fórmula:C27H28Cl2N4O4SForma y color:SolidPeso molecular:575.51GW 9578
CAS:GW 9578 is a PPARα agonist with potent lipid-lowering activity for the study of psoriasis, arthritis, alopecia, asthma and type I diabetes.Fórmula:C26H34F2N2O3SPureza:98%Forma y color:SolidPeso molecular:492.62Peliglitazar racemate
CAS:Peliglitazar racemate(BMS 426707-01 racemate) is the racemate of Peliglitazar.Peliglitazar racemate may be used as a potential antidiabetic and anti-obesityFórmula:C30H30N2O7Pureza:97.75%Forma y color:SolidPeso molecular:530.57BVT.13
CAS:BVT.13 is an orally active selective PPARγ agonist with antidiabetic activity comparable to rosiglitazone, supporting research in metabolic regulation.Fórmula:C18H11Cl2N3O4Pureza:98.59%Forma y color:White SolidPeso molecular:404.2FTX-6746
CAS:FTX-6746 is an orally active and selective PPARG reverse inhibitor with anticancer activity. It can be used in research on urothelial carcinoma.Fórmula:C16H7ClF2N2OPureza:98.68%Forma y color:SolidPeso molecular:316.69GSK376501A
CAS:GSK376501A is a selective and effective modulator of peroxisome proliferator-activated receptor γ (PPARγ) for the study of type 2 diabetes.Fórmula:C32H37NO6Pureza:97.71% - >99.99%Forma y color:White SolidPeso molecular:531.64Pparδ agonist 2
CAS:Pparδ agonist 2 is an agonist of PPARδ.Fórmula:C20H18F3N3O3SPureza:98%Forma y color:SolidPeso molecular:437.44Daltroban
CAS:Daltroban (SKF 96148) is a specific thromboxane A2 (TXA2) receptor antagonist.Fórmula:C16H16ClNO4SPureza:99.66%Forma y color:SolidPeso molecular:353.82Ref: TM-T15049
1mg55,00€1mL*10mM (DMSO)111,00€5mg122,00€10mg177,00€25mg295,00€50mg420,00€100mg572,00€200mg772,00€FX-909
CAS:FX-909 is a covalent peroxisome proliferator-activated receptor gamma ( PPARG ) inverse agonist. FX-909 can be used for the research of cancer .Fórmula:C17H10F2N2O3SPureza:99.53%Forma y color:White SolidPeso molecular:360.33Saroglitazar
CAS:Saroglitazar (Lipaglyn) is an agonist of PPAR with EC50 values of 0.65 pM and 3 nM for PPARα and PPARγ.Fórmula:C25H29NO4SPureza:98.51%Forma y color:SolidPeso molecular:439.57PPARα-MO-1
CAS:PPARα-MO-1 is a potent modulator of PPARα.Fórmula:C27H37NO5Pureza:98%Forma y color:SolidPeso molecular:455.59LG100754
CAS:LG100754 (UVI 2112) is an insulin sensitizer and RXR modulator, antagonizing RXR homodimers while agonizing RXR:PPARα/γ heterodimers.Fórmula:C26H36O3Forma y color:White SolidPeso molecular:396.56
