PPAR
Los receptores activados por proliferadores de peroxisomas (PPARs) son un grupo de proteínas receptoras nucleares que funcionan como factores de transcripción regulando la expresión de genes involucrados en el metabolismo, particularmente en el almacenamiento de ácidos grasos y el metabolismo de la glucosa. Los inhibidores de PPAR son herramientas importantes para estudiar trastornos metabólicos como la diabetes, la obesidad y las enfermedades cardiovasculares. Estos inhibidores pueden modular el metabolismo de los lípidos, la sensibilidad a la insulina y la inflamación, lo que los convierte en valiosos en la investigación terapéutica. En CymitQuimica, ofrecemos una gama de inhibidores de PPAR para apoyar su investigación en enfermedades metabólicas, endocrinología y desarrollo de fármacos.
Se han encontrado 175 productos para "PPAR".
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
E0924G
CAS:E0924G is an orally active PPARδ agonist with an EC50 of 2.82 μM. It enhances the upregulation of osteoprotegerin (OPG) expression, with an EC50 of 0.29 μM. E0924G reduces RANKL-induced osteoclast differentiation and inhibits F-actin ring formation in RAW264.7 macrophages. Additionally, E0924G modulates bone density and bone loss in models of ovariectomy (OVX) and age-related osteoporosis.Fórmula:C12H12N2O3Forma y color:SolidPeso molecular:232.24(±)-CBCQ
CAS:(±)-CBCQ, an oxidation product of cannabidiol, exhibits an EC50 value of 14.7 μM for the activation of peroxisome proliferator-activated receptor γ (PPAR-γ).Fórmula:C21H28O3Forma y color:SolidPeso molecular:328.45PPARγ agonist 16
CAS:PPARγ agonist16 (Compound 4G) is a PPARγ agonist that competitively binds to the ligand-binding domain (LBD) of PPARγ with an IC50 of 1790 nM. It reduces ear swelling in mouse models and exhibits antihyperglycemic activity in mice with Streptozotocin-induced diabetes.Fórmula:C19H14BrNO4SForma y color:SolidPeso molecular:432.29Tesaglitazar
CAS:Tesaglitazar is a potent and selective peroxide PPARα / γ receptor dual agonist with a more potent affinity for PPARγ than PPARα, The EC50 values for rat PPARαFórmula:C20H24O7SPureza:99.95%Forma y color:SolidPeso molecular:408.47Ref: TM-T17044
1mg43,00€1mL*10mM (DMSO)92,00€5mg93,00€10mg130,00€25mg241,00€50mg405,00€100mg632,00€200mg875,00€Inolitazone dihydrochloride
CAS:Inolitazone dihydrochloride is an effective, high-affinity PPARγ agonist; its biological activity is dependent on PPARγ (IC50:0.8 nM) to inhibit cell growth.Fórmula:C27H28Cl2N4O4SForma y color:SolidPeso molecular:575.51FTX-6746
CAS:FTX-6746 is an orally active and selective PPARG reverse inhibitor with anticancer activity. It can be used in research on urothelial carcinoma.Fórmula:C16H7ClF2N2OPureza:98.68%Forma y color:SolidPeso molecular:316.69Daltroban
CAS:Daltroban (SKF 96148) is a specific thromboxane A2 (TXA2) receptor antagonist.Fórmula:C16H16ClNO4SPureza:99.66%Forma y color:SolidPeso molecular:353.82Ref: TM-T15049
1mg55,00€1mL*10mM (DMSO)111,00€5mg122,00€10mg177,00€25mg295,00€50mg420,00€100mg572,00€200mg772,00€FX-909
CAS:FX-909 is a covalent peroxisome proliferator-activated receptor gamma ( PPARG ) inverse agonist. FX-909 can be used for the research of cancer .Fórmula:C17H10F2N2O3SPureza:99.53%Forma y color:White SolidPeso molecular:360.33Saroglitazar
CAS:Saroglitazar (Lipaglyn) is an agonist of PPAR with EC50 values of 0.65 pM and 3 nM for PPARα and PPARγ.Fórmula:C25H29NO4SPureza:98.51%Forma y color:SolidPeso molecular:439.57Pparδ agonist 2
CAS:Pparδ agonist 2 is an agonist of PPARδ.Fórmula:C20H18F3N3O3SPureza:98%Forma y color:SolidPeso molecular:437.44BVT.13
CAS:BVT.13 is an orally active selective PPARγ agonist with antidiabetic activity comparable to rosiglitazone, supporting research in metabolic regulation.Fórmula:C18H11Cl2N3O4Pureza:98.59%Forma y color:White SolidPeso molecular:404.2GW 9578
CAS:GW 9578 is a PPARα agonist with potent lipid-lowering activity for the study of psoriasis, arthritis, alopecia, asthma and type I diabetes.Fórmula:C26H34F2N2O3SPureza:98%Forma y color:SolidPeso molecular:492.62ARH-049020
CAS:ARH-049020, a peroxisome proliferator-activated receptor (PPAR) agonist, is used potentially for the treatment of insulin resistance and type 2 diabetes.Fórmula:C24H31NO6Pureza:99.45% - 99.79%Forma y color:SolidPeso molecular:429.51PPARα-MO-1
CAS:PPARα-MO-1 is a potent modulator of PPARα.Fórmula:C27H37NO5Pureza:98%Forma y color:SolidPeso molecular:455.59LG100754
CAS:LG100754 (UVI 2112) is an insulin sensitizer and RXR modulator, antagonizing RXR homodimers while agonizing RXR:PPARα/γ heterodimers.Fórmula:C26H36O3Forma y color:White SolidPeso molecular:396.56Chiglitazar
CAS:Chiglitazar is a PPAR α/γ/δ agonist and insulin sensitizer used in the treatment of type 2 diabetes mellitus , anti-inflammatory and anti-fibrotic.Fórmula:C36H29FN2O4Pureza:99.81%Forma y color:SolidPeso molecular:572.63Peliglitazar racemate
CAS:Peliglitazar racemate(BMS 426707-01 racemate) is the racemate of Peliglitazar.Peliglitazar racemate may be used as a potential antidiabetic and anti-obesityFórmula:C30H30N2O7Pureza:97.75%Forma y color:SolidPeso molecular:530.57Reglitazar
CAS:Reglitazar, a dual PPARα/γ agonist, enhances insulin signaling, reduces insulin resistance, and lowers hypertriglyceridemia in obese rats.Fórmula:C22H20N2O5Pureza:97.07% - 98.72%Forma y color:SolidPeso molecular:392.4THR-0921
CAS:THR-0921 (CLX-0921) is a peroxisome proliferator-activated receptor (PPAR) agonist that can be used to study cardiovascular and metabolic diseases.Fórmula:C28H25NO7SPureza:100% - 99.83%Forma y color:White SolidPeso molecular:519.57GSK376501A
CAS:GSK376501A is a selective and effective modulator of peroxisome proliferator-activated receptor γ (PPARγ) for the study of type 2 diabetes.Fórmula:C32H37NO6Pureza:97.71% - >99.99%Forma y color:White SolidPeso molecular:531.64
