PPAR
Los receptores activados por proliferadores de peroxisomas (PPARs) son un grupo de proteínas receptoras nucleares que funcionan como factores de transcripción regulando la expresión de genes involucrados en el metabolismo, particularmente en el almacenamiento de ácidos grasos y el metabolismo de la glucosa. Los inhibidores de PPAR son herramientas importantes para estudiar trastornos metabólicos como la diabetes, la obesidad y las enfermedades cardiovasculares. Estos inhibidores pueden modular el metabolismo de los lípidos, la sensibilidad a la insulina y la inflamación, lo que los convierte en valiosos en la investigación terapéutica. En CymitQuimica, ofrecemos una gama de inhibidores de PPAR para apoyar su investigación en enfermedades metabólicas, endocrinología y desarrollo de fármacos.
Se han encontrado 175 productos para "PPAR".
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Cevoglitazar
CAS:Cevoglitazar (LBM-642) is a PPARɑ agonist and PPARγ agonist. Cevoglitazar potently reduces food intake and body weight in obese mice and cynomolgus monkeys.Fórmula:C27H21F3N2O6SPureza:97%Forma y color:SolidPeso molecular:558.53Farglitazar
CAS:Farglitazar (GI-262570) is a PPAR-γ agonist and insulin sensitizer used in the study of diabetes.Fórmula:C34H30N2O5Pureza:99.4% - 99.86%Forma y color:SolidPeso molecular:546.61BAY-0069
CAS:BAY-0069 is a potent and selective PPARγ transactivator that inhibits human PPARγ and murine PPARγ with IC50s of 6.3 nM and 24 nM, respectively.BAY-0069 can beFórmula:C22H16BrN3O4Pureza:99.42%Forma y color:SoildPeso molecular:466.28Dazmegrel
CAS:Dazmegrel (UK 38,485) is a thromboxane A2 (TXA2) synthase inhibitor for the prevention of increased whole platelet aggregation in normal pregnancy.Fórmula:C16H17N3O2Pureza:98.81%Forma y color:SolidPeso molecular:283.33BAY-4931
CAS:BAY-4931 is a powerful, covalent, and selective inverse-agonist of PPARγ, exhibiting an IC50 value of 0.17 nM.Fórmula:C22H16ClN3O4Pureza:99.73%Forma y color:SoildPeso molecular:421.83K-111
CAS:K-111 is a PPAR alpha agonist. K-111 improves insulin resistance, reducing bodyweight, and ameliorating atherogenic dyslipidemia.Fórmula:C18H25Cl3O2Pureza:99.64% - 99.95%Forma y color:SolidPeso molecular:379.75Linotroban
CAS:Linotroban（CL-871502） is a potent selective thromboxane (TXA2) receptor antagonist with antithrombotic activity.Fórmula:C14H15NO5S2Pureza:97.95% - >99.99%Forma y color:SolidPeso molecular:341.4Indeglitazar
CAS:Indeglitazar (PPM 204) is orally available pan-agonist of PPAR (PPAR subtypes alpha (α), delta (δ), and gamma (γ)).Fórmula:C19H19NO6SPureza:99.45%Forma y color:SolidPeso molecular:389.42PPARδ agonist 9
CAS:PPARδ agonist 9 (compound 21), with an EC50 of 3.6 nM, is effective in vivo, decreasing serum MCP-1 concentrations in mice and markedly reducing atheroscleroticFórmula:C26H28ClF3N4O3SPureza:98%Forma y color:SolidPeso molecular:569.04Edaglitazone
CAS:Edaglitazone (R-483) is a PPARγ agonist with antiplatelet activity that can be used in studies of diabetes and obesity.Fórmula:C24H20N2O4S2Pureza:98%Forma y color:SolidPeso molecular:464.56KD-3010
CAS:KD-3010 (Kalypsys) is an orally active potent and selective PPARδ agonist for the study of liver injury.Fórmula:C30H33F3N2O8S2Pureza:99.61%Forma y color:SolidPeso molecular:670.72AVE-8134
CAS:AVE-8134 is an agonist of PPARα. For human and rodent PPARα receptor, the EC50 values are 100 and 3000 nM, respectively.Fórmula:C22H23NO5Pureza:98%Forma y color:SolidPeso molecular:381.42PPAR agonist 1
CAS:PPAR agonist 1 is an agonist of PPAR α/γ, used for reducing blood glucose, lipid levels, reducing body weight, and lowering cholesterol.Fórmula:C20H25NO6SPureza:98%Forma y color:SolidPeso molecular:407.48Darglitazone
CAS:Darglitazone (CP-86325) is a potent, selective agonist of PPAR-γ with antidiabetic actions.Fórmula:C23H20N2O4SPureza:99.76%Forma y color:SolidPeso molecular:420.48Imiglitazar
CAS:Imiglitazar (TAK559) is a potent PPAR-β/δ receptor agonist with hypoglycemic effects.Fórmula:C28H26N2O5Pureza:97.33%Forma y color:SolidPeso molecular:470.52U-46619
CAS:U-46619 is an effective thromboxane A2 (TXA2) agonist and a thromboxane A2 analog (endoperoxide), capable of inducing contraction in the aortic smooth muscle (Fórmula:C21H34O4Pureza:98%Forma y color:Transparent LiquidPeso molecular:350.49LCB-2853
CAS:LCB-2853 is a potent thromboxane A2/prostaglandin H2 (TXA2/PGH2) receptor antagonist with antiplatelet aggregation, antivasospasm, and antithrombotic effects.Fórmula:C21H24ClNO4SPureza:97.15%Forma y color:SolidPeso molecular:421.94PPARγ agonist 8
CAS:PPARγ agonist 8, a compound that acts on the peroxisome proliferator-activated receptor gamma (PPARγ), has been shown to stimulate peroxisome proliferatorFórmula:C19H12F4O2SPureza:98%Forma y color:SolidPeso molecular:380.36Ragaglitazar
CAS:Ragaglitazar(NNC-61-0029) is a potent dual activator of PPARγ and PPARα.Cost-effective and quality-assured.Fórmula:C25H25NO5Pureza:97.46% - 98.56%Forma y color:SolidPeso molecular:419.47Inolitazone
CAS:Inolitazone (RS5444) a high-affinity PPARγ agonist. Inolitazone exhibits IC50 for growth inhibition is ~0.8 nM in vitro.Fórmula:C27H26N4O4SPureza:99.41% - 99.53%Forma y color:SolidPeso molecular:502.58Ref: TM-T15581
500mgA consultar1mg70,00€5mg149,00€1mL*10mM (DMSO)178,00€10mg230,00€25mg374,00€50mg532,00€100mg713,00€
