PPAR
Los receptores activados por proliferadores de peroxisomas (PPARs) son un grupo de proteínas receptoras nucleares que funcionan como factores de transcripción regulando la expresión de genes involucrados en el metabolismo, particularmente en el almacenamiento de ácidos grasos y el metabolismo de la glucosa. Los inhibidores de PPAR son herramientas importantes para estudiar trastornos metabólicos como la diabetes, la obesidad y las enfermedades cardiovasculares. Estos inhibidores pueden modular el metabolismo de los lípidos, la sensibilidad a la insulina y la inflamación, lo que los convierte en valiosos en la investigación terapéutica. En CymitQuimica, ofrecemos una gama de inhibidores de PPAR para apoyar su investigación en enfermedades metabólicas, endocrinología y desarrollo de fármacos.
Se han encontrado 169 productos de "PPAR"
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K-111
CAS:K-111 is a PPAR alpha agonist. K-111 improves insulin resistance, reducing bodyweight, and ameliorating atherogenic dyslipidemia.Fórmula:C18H25Cl3O2Pureza:99.64% - 99.88%Forma y color:SolidPeso molecular:379.75BAY-4931
CAS:<p>BAY-4931 is a powerful, covalent, and selective inverse-agonist of PPARγ, exhibiting an IC50 value of 0.17 nM.</p>Fórmula:C22H16ClN3O4Pureza:99.47%Forma y color:SoildPeso molecular:421.83Linotroban
CAS:Linotroban（CL-871502） is a potent selective thromboxane (TXA2) receptor antagonist with antithrombotic activity.Fórmula:C14H15NO5S2Pureza:97.95% - >99.99%Forma y color:SolidPeso molecular:341.4Darglitazone
CAS:Darglitazone (CP-86325) is a potent, selective agonist of PPAR-γ with antidiabetic actions.Fórmula:C23H20N2O4SPureza:99.76%Forma y color:SolidPeso molecular:420.48KD-3010
CAS:<p>KD-3010 (Kalypsys) is an orally active potent and selective PPARδ agonist for the study of liver injury.</p>Fórmula:C30H33F3N2O8S2Pureza:99.61%Forma y color:SolidPeso molecular:670.72PPARγ agonist 8
CAS:PPARγ agonist 8, a compound that acts on the peroxisome proliferator-activated receptor gamma (PPARγ), has been shown to stimulate peroxisome proliferatorFórmula:C19H12F4O2SPureza:98%Forma y color:SolidPeso molecular:380.36U-46619
CAS:U-46619 is an effective thromboxane A2 (TXA2) agonist and a thromboxane A2 analog (endoperoxide), capable of inducing contraction in the aortic smooth muscle (Fórmula:C21H34O4Pureza:98%Forma y color:SolidPeso molecular:350.49PPARδ agonist 9
CAS:PPARδ agonist 9 (compound 21), with an EC50 of 3.6 nM, is effective in vivo, decreasing serum MCP-1 concentrations in mice and markedly reducing atheroscleroticFórmula:C26H28ClF3N4O3SPureza:98%Forma y color:SolidPeso molecular:569.04PPAR agonist 1
CAS:PPAR agonist 1 is an agonist of PPAR α/γ, used for reducing blood glucose, lipid levels, reducing body weight, and lowering cholesterol.Fórmula:C20H25NO6SPureza:98%Forma y color:SolidPeso molecular:407.48LCB-2853
CAS:LCB-2853 is a potent thromboxane A2/prostaglandin H2 (TXA2/PGH2) receptor antagonist with antiplatelet aggregation, antivasospasm, and antithrombotic effects.Fórmula:C21H24ClNO4SPureza:97.15%Forma y color:SolidPeso molecular:421.94Edaglitazone
CAS:Edaglitazone (R-483) is a PPARγ agonist with antiplatelet activity that can be used in studies of diabetes and obesity.Fórmula:C24H20N2O4S2Pureza:98%Forma y color:SolidPeso molecular:464.56Imiglitazar
CAS:<p>Imiglitazar (TAK559) is a potent PPAR-β/δ receptor agonist with hypoglycemic effects.</p>Fórmula:C28H26N2O5Pureza:97.33%Forma y color:SolidPeso molecular:470.52CRX000227
CAS:<p>CRX000227 is a PPAR modulator suitable for researching metabolic and cell proliferative disorders [1].</p>Fórmula:C25H24N4O2SPureza:98%Forma y color:SolidPeso molecular:444.55Ragaglitazar
CAS:Ragaglitazar(NNC-61-0029) is a potent dual activator of PPARγ and PPARα.Cost-effective and quality-assured.Fórmula:C25H25NO5Pureza:97.46% - 98.56%Forma y color:SolidPeso molecular:419.47Inolitazone
CAS:Inolitazone (RS5444) a high-affinity PPARγ agonist. Inolitazone exhibits IC50 for growth inhibition is ~0.8 nM in vitro.Fórmula:C27H26N4O4SPureza:99.41% - 99.53%Forma y color:SolidPeso molecular:502.58PPARγ agonist 10
CAS:PPARγ agonist 10 (compound 33g) serves as a PPARγ agonist, enhancing insulin secretion, glucose uptake, and insulin sensitivity in βTC6 cells [1].Fórmula:C17H14N4O3S2Forma y color:SolidPeso molecular:386.45Anti-NASH agent 2
CAS:<p>Anti-NASH agent 2 (compound 21) is an inhibitor of neolipogenesis activity and α-SMA gene expression. It improves hepatic steatosis, edema, inflammatory infiltration, and liver fibrosis in NASH mouse models.</p>Fórmula:C32H51N3O2Forma y color:SolidPeso molecular:509.766PPARγ agonist 17
CAS:PPARγ agonist17 (Compound C1) is an orally active PPARγ agonist. It enhances PPARγ activity, arrests the cell cycle of HT-29 cells at the G2/M phase, inhibits cell migration, and induces apoptosis. PPARγ agonist17 exhibits broad-spectrum antiproliferative activity against cancer cells with relatively low toxicity to normal cells and does not cross the blood-brain barrier.Fórmula:C48H63NO7Forma y color:SolidPeso molecular:766.016PPARγ modulator-2
CAS:PPARγmodulator-2 (Compound (R)-2n) is a reversible modulator of PPARγ, inhibiting the PPARγ ligand-binding domain (LBD) with an IC50 of 41 nM. It helps lower blood glucose levels, improves glucose tolerance and insulin sensitivity, and demonstrates antidiabetic activity in db/db mouse models.Fórmula:C26H21NO7S3SeForma y color:SolidPeso molecular:634.6Amezalpat
CAS:Amezalpat is a PPARα antagonist with an IC50 of 58 nM [nanomolar]. Amezalpat also exhibits antitumor activity.Fórmula:C34H41N3O4Forma y color:SolidPeso molecular:555.707
