HMG-CoA reductasa
La HMG-CoA Reductasa es una enzima clave en la vía del mevalonato, responsable de la síntesis de colesterol y otros isoprenoides. Los inhibidores de la HMG-CoA reductasa, comúnmente conocidos como estatinas, se utilizan ampliamente para reducir los niveles de colesterol y disminuir el riesgo de enfermedades cardiovasculares. Estos inhibidores también tienen beneficios potenciales en la investigación sobre el cáncer y las enfermedades neurodegenerativas. En CymitQuimica, ofrecemos una variedad de inhibidores de la HMG-CoA reductasa para apoyar su investigación en el metabolismo lipídico, la salud cardiovascular y el desarrollo terapéutico.
Se han encontrado 33 productos de "HMG-CoA reductasa"
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Atorvastatin lactone
CAS:Atorvastatin lactone is a prodrug form of atorvastatin. Which is an orally active 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor.Fórmula:C33H33FN2O4Pureza:98.05% - 98.16%Forma y color:SolidPeso molecular:540.62Lipid Metabolism Compound Library
<p>A unique collection of 492 compounds targeting lipid metabolism, can be used for high-throughput screening (HTS) and high-content screening (HCS).</p>Forma y color:Odour SolidGanoderenic acid K
CAS:<p>Ganoderenic acid K, from Ganoderma lucidum, inhibits HMG-CoA reductase with an IC50 of 16.5 μM.</p>Fórmula:C32H44O9Forma y color:SolidPeso molecular:572.69HMG-CoA Reductase-IN-1
HMG-CoA Reductase-IN-1 is an inhibitor of HMG-CoA reductase, demonstrating strong inhibitory activity on HMGR and affinity for OATP1B1, with pIC50 and pKmFórmula:C27H29N3O7Forma y color:SolidPeso molecular:507.54(Rac)-5-Keto Fluvastatin
CAS:(Rac)-5-Keto Fluvastatin (rac 5-Keto Fluvastatin) is an impurity of Fluvastatin which is an inhibitor of HMG-CoA reductase.Fórmula:C24H24FNO4Pureza:95.04%Forma y color:SolidPeso molecular:409.45(3S,5R)-Fluvastatin D6 sodium
CAS:(3S,5R)-Fluvastatin D6 sodium: deuterium-labeled synthetic HMG-CoA reductase inhibitor with 8 nM IC50.Fórmula:C24H25FNNaO4Pureza:98%Forma y color:SolidPeso molecular:439.49Rawsonol
CAS:Rawsonol is a HMG-CoA reductase inhibitor from the tropical green alga Avrainvillea rawsoni.Fórmula:C29H24Br4O7Forma y color:SolidPeso molecular:804.11L 645164
CAS:L 645164 is an inhibitor of hydroxymethylglutaryl-CoA reductase.Fórmula:C22H23FO3Forma y color:SolidPeso molecular:354.4124,25-Epoxycholesterol
CAS:24,25-Epoxycholesterol is an oxysterol agonist of the liver X receptor, known to inhibit the activity of 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMG-CoA reductase) in hepatic cells. Additionally, 24,25-Epoxycholesterol plays a role in regulating cholesterol metabolism within the liver.Fórmula:C27H44O2Peso molecular:400.64Rosuvastatin Sodium
CAS:Rosuvastatin Sodium (ZD4522 Sodium) is a competitive HMG-CoA reductase (HMGCR) inhibitor (IC50=11 nM) with lipid-lowering and anti-atherosclerotic effects.Fórmula:C22H27FN3NaO6SForma y color:SolidPeso molecular:503.52Pravastatin lactone
CAS:<p>Pravastatin lactone, a non-enzymatic stomach derivative of pravastatin, inhibits HMG-CoA reductase and stems from mevastatin.</p>Fórmula:C23H34O6Forma y color:SolidPeso molecular:406.519Atorvastatin calcium trihydrate
CAS:Atorvastatin is used to inhibits HMG-CoA reductase for lowering blood cholesterol and for prevention of events associated with cardiovascular disease.Fórmula:C66H74CaF2N4O13Forma y color:SolidPeso molecular:1209.39PPD 10558
CAS:PPD 10558, a HMG-CoA reductase inhibitor, is used potentially for treatment of primary hypercholesterolemia.Fórmula:C34H37FN2O6Forma y color:SolidPeso molecular:588.677-Ketocholesterol
CAS:7-Ketocholesterol is a metabolite of CholesterolFórmula:C27H44O2Pureza:97.59% - 98.84%Forma y color:SolidPeso molecular:400.65Tenivastatin
CAS:Tenivastatin (Simvastatin acid) is an anti-hyperlipidemic HMG-CoA reductase inhibitor used in the study of primary hyperlipidemia.Fórmula:C25H40O6Pureza:99.56%Forma y color:SolidPeso molecular:436.58Simvastatin acid ammonium
CAS:Simvastatin acid ammonium (Tenivastatin ammonium) is an HMG-CoA reductase (HMGCR) inhibitor.Fórmula:C25H43NO6Pureza:98.3%Forma y color:SolidPeso molecular:453.61Pravastatin
CAS:Pravastatin (CS-514) is a competitive HMG-CoA reductase inhibitor with an IC50 of 5.6 μM for sterol synthesis, capable of lowering serum cholesterol.Fórmula:C23H36O7Pureza:99.99%Forma y color:White PowderPeso molecular:424.534-Acetylsimvastatin
CAS:4-Acetylsimvastatin is acetylated simvastatin. Simvastatin is a competitive inhibitor of HMG-CoA reductase (Ki: 0.2 nM).Fórmula:C27H40O6Pureza:98%Forma y color:SolidPeso molecular:460.6(3S,5R)-Pitavastatin calcium
CAS:(3S,5R)-Pitavastatin calcium is the enantiomer of Pitavastatin which is a potent HMG-CoA reductase inhibitor.Fórmula:C25H26CaFNO4Pureza:98%Forma y color:SolidPeso molecular:463.562(3S,5S)-Pitavastatin calcium
CAS:(3S,5S)-Pitavastatin calcium is the 3-epimer of Pitavastatin which is a potent HMG-CoA reductase inhibitor.Fórmula:C25H26CaFNO4Pureza:98%Forma y color:SolidPeso molecular:463.562
