AhR
El Receptor de Hidrocarburos Aromáticos (AhR) es un factor de transcripción activado por ligandos que desempeña un papel crítico en la regulación de las respuestas biológicas a contaminantes ambientales, como las dioxinas. AhR también está involucrado en el metabolismo de xenobióticos y en la regulación de las respuestas inmunitarias, la proliferación y la diferenciación celular. La desregulación de la señalización de AhR está vinculada a diversas enfermedades, incluido el cáncer y los trastornos autoinmunes. En CymitQuimica, ofrecemos una gama de inhibidores de AhR para apoyar su investigación en toxicología, biología del cáncer e inmunología.
Se han encontrado 42 productos de "AhR"
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GNF351
CAS:GNF351: Full AHR antagonist, inhibits DRE-dependent/independent activity, low toxicity, binds AHR (IC50: 62 nM).Fórmula:C24H25N7Pureza:98.43%Forma y color:SolidPeso molecular:411.5BAY 2416964
CAS:BAY 2416964 is a small molecule inhibitor that selectively targets aromatic receptor (AhR) and is commonly used in tumor research. Cost-effective and quality-assured.Fórmula:C18H18ClN5O3Pureza:99.15% - 99.85%Forma y color:SolidPeso molecular:387.82Mexiletine hydrochloride
CAS:Mexiletine hydrochloride is a lidocaine-like antiarrhythmic (Class IB) and anesthetic, stabilizing heartbeats by inhibiting sodium in cardiac cells.Fórmula:C11H18ClNOPureza:99.88%Forma y color:White To Off-White SolidPeso molecular:215.72Nimodipine
CAS:Nimodipine (BAY-e 9736), a 1, 4-dihydropyridine calcium channel blocker, acts primarily on vascular smooth muscle cells.Fórmula:C21H26N2O7Pureza:99.64% - 99.79%Forma y color:SolidPeso molecular:418.44Leflunomide
CAS:Leflunomide (HWA486) is an immunomodulatory agent used in the therapy of rheumatoid arthritis and psoriatic arthritis.Fórmula:C12H9F3N2O2Pureza:99.52% - 99.96%Forma y color:Off White Crystalline SolidPeso molecular:270.21Diosmin
CAS:Diosmin (Venosmine) is a bioflavonoid that strengthens vascular walls.Fórmula:C28H32O15Pureza:97.90%Forma y color:Greyish-Yellow Or Light Yellow Hygroscopic PowderPeso molecular:608.54AHR Inhibitor I-103
CAS:AHR Inhibitor I-103 is an aryl hydrocarbon receptor (AHR) inhibitor with anticancer activity used in the study of breast cancer and acute myeloid leukemia.Fórmula:C21H17FN6Pureza:98.70%Forma y color:SoildPeso molecular:372.4StemRegenin 1 Hydrochloride
CAS:StemRegenin 1 Hydrochloride is an AhR antagonist (IC₅₀ = 127 nM) that inhibits RANKL-induced osteoclast generation and differentiation.Fórmula:C24H24ClN5OSPureza:99.94%Forma y color:SolidPeso molecular:466WAY-605471
CAS:WAY-605471 is a AHR antagonist with IC50 of 0.5 - 1 μM.Fórmula:C14H15NO3S2Pureza:99.62%Forma y color:SolidPeso molecular:309.4KYN-101
CAS:<p>KYN-101 is an and aryl hydrocarbon receptor (AHR) inhibitor with anticancer activity. KYN-101 is used for the study of breast cancer and acute myeloid leukemia.</p>Fórmula:C22H19FN6Pureza:98.35%Forma y color:SolidPeso molecular:386.433',4'-Dimethoxyflavone
CAS:3',4'-Dimethoxyflavone is a standard compound of flavonoids with numerous medicinal activities.Fórmula:C17H14O4Pureza:98.05%Forma y color:SolidPeso molecular:282.29MeBIO
CAS:MeBIO is an agonist of aryl hydrocarbon receptor, with IC50 of 44 and 55 μM for GSK-3 and CDK1/CyclinB, respectively. MeBIO does not affect GSK-3β.Fórmula:C17H12BrN3O2Pureza:99.64%Forma y color:SolidPeso molecular:370.2L-Kynurenine
CAS:L-Kynurenine ((S)-Kynurenine)) is an endogenous agonist of aryl hydrocarbon receptor (AHR) ,inhibits allogeneic T cell proliferation. High-Quality, Low-Cost!Fórmula:C10H12N2O3Pureza:98.44% - 99.91%Forma y color:Light Yellow CrystallinePeso molecular:208.21YL-109
CAS:YL-109, a novel anticancer agent, can inhibit breast Y cell growth and invasiveness in vitro and in vivo.Fórmula:C14H11NO2SPureza:99.77% - ≥95%Forma y color:SolidPeso molecular:257.31ITE
CAS:ITE is a potent endogenous agonist of aryl hydrocarbon receptor (AhR) (Ki : 3 nM), has immunosuppressive activity.Fórmula:C14H10N2O3SPureza:97.91% - 99.14%Forma y color:SolidPeso molecular:286.31PDM11
CAS:PDM11 (1-[2-(4-Chloro-phenyl)-vinyl]-3,5-diMeth) is an antagonist of aryl hydrocarbon receptor (AhR)Fórmula:C16H15ClO2Pureza:99.88%Forma y color:SolidPeso molecular:274.74Benzyl butyl phthalate
CAS:Benzyl butyl phthalate (1,2-benzenedicarboxylic acid) is used as a plasticizer for PVC.Fórmula:C19H20O4Pureza:99.02%Forma y color:Colourless Liquid Oily LiquidPeso molecular:312.36Indole-3-pyruvic acid
CAS:Indole-3-pyruvic acid is a precursor for the plant growth hormone indole-3-acetic acid.Fórmula:C11H9NO3Pureza:98.89% - 99.21%Forma y color:Off White CrystalsPeso molecular:203.19Tapinarof
CAS:Tapinarof (Benvitimod) is targeted as a topical cream treatment for psoriasis, a chronic autoimmune skin disease.Fórmula:C17H18O2Pureza:99.64% - >99.99%Forma y color:SolidPeso molecular:254.32PD98059
CAS:PD98059 is an MEK inhibitor that inhibits MEK1 and MEK2 (IC50=2/50 μM) and is non-ATP-competitive.Fórmula:C16H13NO3Pureza:98.63% - >99.99%Forma y color:Yellow SolidPeso molecular:267.28
