CAMK
Calcium/Calmodulin-Dependent Protein Kinase (CaMK) inhibitors are specialized compounds that inhibit the activity of CaMK, a critical kinase involved in a range of cellular processes, particularly within the nervous system. CaMK is essential for translating calcium signals into various cellular responses, including synaptic plasticity, memory formation, and gene expression. Dysregulation of CaMK activity is linked to several neurological disorders, making these inhibitors valuable tools in the study of synaptic signaling, learning, and memory. By using CaMK inhibitors, researchers can explore the molecular mechanisms underlying cognitive function and synaptic plasticity. At CymitQuimica, we provide high-quality CaMK inhibitors to support your research in synaptic plasticity, cognitive function, and neuropharmacology.
Se han encontrado 73 productos de "CAMK"
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Trifluoperazine dihydrochloride
CAS:Trifluoperazine dihydrochloride (SKF5019) is a potent dopamine D2 receptor inhibitor used as an antipsychotic and an antiemetic.Fórmula:C21H26Cl2F3N3SPureza:99.57% - 99.96%Forma y color:Cream Fine PowderPeso molecular:480.43Y-33075 dihydrochloride
CAS:Y-33075 dihydrochloride is a selective inhibitor of ROCK(IC50 of 3.6 nM).Fórmula:C16H18Cl2N4OPureza:98.88% - 99.89%Forma y color:SolidPeso molecular:353.25Ref: TM-T13384L
1mg35,00€5mg70,00€10mg107,00€25mg202,00€50mg360,00€100mg538,00€200mg772,00€1mL*10mM (DMSO)82,00€A-3 hydrochloride
CAS:<p>A-3 hydrochloride: potent, reversible kinase antagonist; permeable; inhibits PKC, CKI, PKA, CKII, MLCK; Ki: 4.3-80 μM.</p>Fórmula:C12H14Cl2N2O2SPureza:99.32%Forma y color:SolidPeso molecular:321.22Elziverine
CAS:<p>Elziverine: oral calmodulin antagonist, inhibits Ca-induced acanthocyte formation, potential for neurological and cognitive disorder treatment.</p>Fórmula:C32H37N3O5Pureza:99.79%Forma y color:SolidPeso molecular:543.65Fasciculic acid A
CAS:Fasciculic acid A is a calmodulin antagonist isolated from mushroom Naematoloma fasciculare.Fórmula:C36H60O8Forma y color:SolidPeso molecular:620.868TAT-CN21 (scrambled)
TAT-CN21(scrambled) is a control peptide lacking specific targeting activity and serves as a negative control for TatCN21. TatCN21 is an effective and selective inhibitory peptide for calcium/calmodulin-dependent protein kinase II (CaMKII).Forma y color:Odour SolidFasciculic acid B
CAS:Fasciculic acid B: ester of fasciculol B, 3-hydroxy-methylglutaric acid; a calmodulin antagonist from Naematoloma fasciculare.Fórmula:C36H60O9Pureza:98%Forma y color:SolidPeso molecular:636.86Encecalinol
CAS:Encecalinol, a compound isolated from the aerial parts of Ageratina grandifolia, acts as a potent inhibitor of calmodulin [1].Fórmula:C14H18O3Forma y color:SolidPeso molecular:234.29CALP2 TFA
CALP2 TFA, a CaM antagonist with 7.9 µM Kd, blocks CaM-dependent enzymes, boosts Ca2+ levels, and activates macrophages.Fórmula:C70H105F3N14O15SForma y color:SolidPeso molecular:1471.72Calmodulin-Dependent Protein Kinase II 290-309 acetate
Calmodulin-Dependent Protein Kinase II 290-309 acetate is an effective antagonist of Ca2+/calmodulin-dependent protein kinase II (IC50 = 52 nM).Fórmula:C105H189N31O26SPureza:96.7%Forma y color:SolidPeso molecular:2333.88Cloxacepride
CAS:cloxacepride is a CaM antagonist that is used to treat asthma disease.Fórmula:C22H27Cl2N3O4Pureza:99.76%Forma y color:SolidPeso molecular:468.37Beauverolide Ja
CAS:Beauverolide Ja: cyclotetradepsipeptide, CaM inhibitor; Kd 0.078 μM, Ki 0.39 μM; from Isaria fumosorosea.Fórmula:C35H46N4O5Forma y color:SolidPeso molecular:602.76CALP2
CAS:CALP2 is a CaM antagonist blocking EF-hand/Ca2+ site; inhibits CaM phosphodiesterase, raises Ca2+, and activates alveolar macrophages.Fórmula:C68H104N14O13SPureza:98%Forma y color:SolidPeso molecular:1357.72Calmodulin-Dependent Protein Kinase II (281-309)
CAS:Calmodulin-Dependent Protein Kinase II (281-309) is a synthetic peptide that can be phosphorylated at Thr286 by PKC and inhibits CaM kinase II (IC50 = 80 nM).Fórmula:C146H254N46O39S3Pureza:98%Forma y color:SolidPeso molecular:3374.06TAT-CN21
TatCN21, with an IC 50 of 77 nM, serves as a potent and selective inhibitor peptide of the calcium/calmodulin-dependent protein kinase II (CaMKII), a ubiquitously-expressed multifunctional serine/threonine protein kinase. It is particularly useful in research pertaining to ischemia and neurodegenerative diseases.Fórmula:C169H303N69O43Forma y color:SolidPeso molecular:3989.65Calmodulin Binding Peptide 1
CAS:Calmodulin Binding Peptide 1, a high-affinity MLCK-derived inhibitor, blocks IP3-induced Ca2+ release.Fórmula:C231H373N69O70S2Pureza:98%Forma y color:SolidPeso molecular:5301.1Acremonidin A
CAS:Acremonidin A, from Purpureocillium lilacinum, is a strong CaM inhibitor binding to hCaM M124C-mBBr with a Kd of 19.40 nM.Fórmula:C33H26O12Forma y color:SolidPeso molecular:614.55Fasciculic acid C
CAS:Fasciculic acid C is a calmodulin antagonist isolated from mushroom Naematoloma fasciculare.Fórmula:C38H63NO11Pureza:98%Forma y color:SolidPeso molecular:709.91RA306
RA306 is an orally active CAMK2 inhibitor that effectively disrupts the PEAK1/CAMK2 signaling pathway. It demonstrates anti-tumor activity by inhibiting proliferation, migration, and invasion of breast cancer cells. Additionally, RA306 shows potential in cardiac disease research, as it improves dilated cardiomyopathy in mice.Forma y color:Odour SolidFluphenazine-N-2-chloroethane (hydrochloride)
CAS:Fluphenazine: antipsychotic, binds dopamine D2 (Ki=0.55nM), inhibits calmodulin. Its derivative adds irreversible D2 antagonism and anticancer potential.Fórmula:C22H27Cl3F3N3SForma y color:SolidPeso molecular:528.89
