CAMK
Calcium/Calmodulin-Dependent Protein Kinase (CaMK) inhibitors are specialized compounds that inhibit the activity of CaMK, a critical kinase involved in a range of cellular processes, particularly within the nervous system. CaMK is essential for translating calcium signals into various cellular responses, including synaptic plasticity, memory formation, and gene expression. Dysregulation of CaMK activity is linked to several neurological disorders, making these inhibitors valuable tools in the study of synaptic signaling, learning, and memory. By using CaMK inhibitors, researchers can explore the molecular mechanisms underlying cognitive function and synaptic plasticity. At CymitQuimica, we provide high-quality CaMK inhibitors to support your research in synaptic plasticity, cognitive function, and neuropharmacology.
Se han encontrado 67 productos para "CAMK".
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Elziverine
CAS:Elziverine: oral calmodulin antagonist, inhibits Ca-induced acanthocyte formation, potential for neurological and cognitive disorder treatment.Fórmula:C32H37N3O5Pureza:99.79%Forma y color:SolidPeso molecular:543.6533A-3 hydrochloride
CAS:A-3 hydrochloride: potent, reversible kinase antagonist; permeable; inhibits PKC, CKI, PKA, CKII, MLCK; Ki: 4.3-80 μM.Fórmula:C12H14Cl2N2O2SPureza:99.32%Forma y color:SolidPeso molecular:321.22Trifluoperazine dihydrochloride
CAS:Trifluoperazine dihydrochloride (SKF5019) is a potent dopamine D2 receptor inhibitor used as an antipsychotic and an antiemetic.Fórmula:C21H26Cl2F3N3SPureza:99.57% - 99.96%Forma y color:SolidPeso molecular:480.417Y-33075 dihydrochloride
CAS:Y-33075 dihydrochloride is a selective inhibitor of ROCK(IC50 of 3.6 nM).Fórmula:C16H18Cl2N4OPureza:98.88% - 99.89%Forma y color:SolidPeso molecular:353.246MLCK Peptide
CAS:MLCK Peptide, a high-affinity (pM), fully reversible CaM-binding peptide, is derived from smooth muscle myosin light-chain kinase [1].Fórmula:C91H156N36O20Forma y color:SolidPeso molecular:2074.44Fasciculic acid C
CAS:Fasciculic acid C is a calmodulin antagonist isolated from mushroom Naematoloma fasciculare.Fórmula:C38H63NO11Pureza:98%Forma y color:SolidPeso molecular:709.91AC3-I, myristoylated
Myristoylated AC3-I is a biologically active peptide and a myristoylated variant of the Autocamtide-3-Derived Inhibitory Peptide (AC3-I).Fórmula:C78H137N21O20Pureza:98%Forma y color:SolidPeso molecular:1689.05TAT-CN21 (scrambled)
TAT-CN21(scrambled) is a control peptide lacking specific targeting activity and serves as a negative control for TatCN21. TatCN21 is an effective and selective inhibitory peptide for calcium/calmodulin-dependent protein kinase II (CaMKII).Forma y color:Odour SolidRA306
RA306 is an orally active CAMK2 inhibitor that effectively disrupts the PEAK1/CAMK2 signaling pathway. It demonstrates anti-tumor activity by inhibiting proliferation, migration, and invasion of breast cancer cells. Additionally, RA306 shows potential in cardiac disease research, as it improves dilated cardiomyopathy in mice.Forma y color:Odour SolidTAT-CN21
TAT-CN21 is a cell-permeable CaMKII inhibitory peptide used to study neuronal excitotoxicity and ischemic injury by blocking CaMKII activity.Fórmula:C169H303N69O43Forma y color:White SolidPeso molecular:3989.65Fluphenazine-N-2-chloroethane (hydrochloride)
CAS:Fluphenazine-N-2-chloroethane hydrochloride is a fluphenazine derivative used as a calmodulin probe.Fórmula:C22H27Cl3F3N3SForma y color:SolidPeso molecular:528.89CALP2 TFA
CALP2 TFA, a CaM antagonist with 7.9 µM Kd, blocks CaM-dependent enzymes, boosts Ca2+ levels, and activates macrophages.Fórmula:C70H105F3N14O15SForma y color:SolidPeso molecular:1471.72Cloxacepride
CAS:cloxacepride is a CaM antagonist that is used to treat asthma disease.Fórmula:C22H27Cl2N3O4Pureza:99.76%Forma y color:SolidPeso molecular:468.373CALP2
CAS:CALP2 is a CaM antagonist blocking EF-hand/Ca2+ site; inhibits CaM phosphodiesterase, raises Ca2+, and activates alveolar macrophages.Fórmula:C68H104N14O13SPureza:98%Forma y color:SolidPeso molecular:1357.72Beauverolide Ja
CAS:Beauverolide Ja: cyclotetradepsipeptide, CaM inhibitor; Kd 0.078 μM, Ki 0.39 μM; from Isaria fumosorosea.Fórmula:C35H46N4O5Forma y color:SolidPeso molecular:602.76CaMKIIδ-IN-1 hydrochloride
CaMKIIδ-IN-1 (Compound 15e) hydrochloride is a pyrimidine-based inhibitor of CaMKIIδ with an IC50 value of 12 nM.Calmodulin Binding Peptide 1
CAS:Calmodulin Binding Peptide 1, a high-affinity MLCK-derived inhibitor, blocks IP3-induced Ca2+ release.Fórmula:C231H373N69O70S2Pureza:98%Forma y color:SolidPeso molecular:5301.1Calmodulin-Dependent Protein Kinase II 290-309 acetate
Calmodulin-Dependent Protein Kinase II 290-309 acetate is an effective antagonist of Ca2+/calmodulin-dependent protein kinase II (IC50 = 52 nM).Fórmula:C105H189N31O26SPureza:96.7%Forma y color:SolidPeso molecular:2333.88Calmodulin-Dependent Protein Kinase II (281-309)
CAS:Calmodulin-Dependent Protein Kinase II (281-309) is a synthetic peptide that can be phosphorylated at Thr286 by PKC and inhibits CaM kinase II (IC50 = 80 nM).Fórmula:C146H254N46O39S3Pureza:98%Forma y color:SolidPeso molecular:3374.06Calmodulin Kinase IINtide, Myristoylated
Myristoylated Calmodulin Kinase IINtide (Myr-CaMKIINtide) serves as a selective and noncompetitive inhibitor of CaMKII [1].Fórmula:C156H275N47O43Pureza:98%Forma y color:SolidPeso molecular:3497.14
