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Proteasas / Proteasoma

Proteasas / Proteasoma

Los inhibidores de proteasas y proteasomas son compuestos que bloquean la actividad de las proteasas y del proteasoma, que están involucrados en la degradación y renovación de proteínas. Estos inhibidores son vitales para estudiar la regulación de la homeostasis proteica, el control del ciclo celular y la apoptosis. Los inhibidores de proteasas y proteasomas también se utilizan en el tratamiento de enfermedades como el cáncer, donde la degradación anormal de proteínas desempeña un papel en la progresión de la enfermedad. Al inhibir las proteasas o el proteasoma, estos compuestos pueden inducir la muerte celular en células cancerosas y son herramientas esenciales tanto en la investigación básica como en el desarrollo terapéutico. En CymitQuimica, ofrecemos una amplia gama de inhibidores de proteasas y proteasomas de alta calidad para apoyar su investigación en bioquímica, biología celular y desarrollo de fármacos.

Subcategorías de "Proteasas / Proteasoma"

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Se han encontrado 1044 productos de "Proteasas / Proteasoma"

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  • Sofosbuvir impurity A

    CAS:
    <p>Sofosbuvir impurity A is an diastereoisomer of Sofosbuvir. Sofosbuvir is anHCV RNA replication inhibitor ,with potent anti-hepatitis C virus activity.</p>
    Fórmula:C22H29FN3O9P
    Pureza:98%
    Forma y color:Solid
    Peso molecular:529.45
  • CP-346086 dihydrate

    CAS:
    <p>CP-346086 dihydrate is a strong oral MTP inhibitor with 2.0 nM IC50, reducing cholesterol and triglycerides in vivo.</p>
    Fórmula:C26H26F3N5O3
    Forma y color:Solid
    Peso molecular:513.521
  • Zetomipzomib maleate

    CAS:
    <p>Zetomipzomib maleate (KZR-616) selectively targets LMP7/2 in immunoproteasomes, potential for autoimmune research.</p>
    Fórmula:C34H46N4O12
    Forma y color:Solid
    Peso molecular:702.758
  • Leptosin D

    CAS:
    <p>Leptosin D, a thiodiketopiperazine alkaloid derived from mushrooms, effectively inhibits tyrosinase activity, demonstrating an inhibition concentration (IC50)</p>
    Fórmula:C25H24N4O3S2
    Forma y color:Solid
    Peso molecular:492.61
  • Sofosbuvir impurity H


    <p>Sofosbuvir impurity H, an diastereoisomer of Sofosbuvir, is the impurity of Sofosbuvir.</p>
    Fórmula:C29H33FN3O10P
    Pureza:98%
    Forma y color:Solid
    Peso molecular:633.56
  • TAPI1 acetate


    <p>TAPI1 acetate (TNF-α processing inhibitor-1) is a TACE (ADAM17) inhibitor that inhibits shedding of TNF-α cytokine receptors; MMP inhibitor .</p>
    Fórmula:C28H41N5O7
    Pureza:98.82% - 99.94%
    Forma y color:Solid
    Peso molecular:559.65
  • HCVP-IN-1

    CAS:
    <p>HCVP-IN-1 (compound 1) is a hepatitis C viral polymerase (HCVP) inhibitor.</p>
    Fórmula:C30H34FN5O3
    Forma y color:Solid
    Peso molecular:531.632
  • TMC647055 Choline salt


    <p>TMC647055 choline salt is a selective and cell-permeating inhibitor of HCV NS5B (IC50: 34 nM).</p>
    Fórmula:C37H53N5O8S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:727.91
  • Cathepsin C-IN-6


    <p>Cathepsin C-IN-6 (compound 2), an E-64c-hydrazideas-derived inhibitor of cathepsin C, possesses anti-inflammatory properties and impedes neutrophil elastase</p>
    Fórmula:C24H35N5O4·xC2HF3O2
    Forma y color:Solid
  • Sitagliptin fenilalanil hydrochloride

    CAS:
    <p>Sitagliptin phenylalanine hydrochloride, a dipeptidyl peptidase-4 (DPP-4) inhibitor [1], is a chemical compound utilized in medical applications.</p>
    Fórmula:C25H25ClF6N6O2
    Forma y color:Solid
    Peso molecular:590.95
  • Cyanopeptolin 954

    CAS:
    <p>Cyanopeptolin 954 is a chlorine-containing Microcystis aeruginosa NIVA Cya 43 chymotrypsin Inhibitor.</p>
    Fórmula:C46H63ClN8O12
    Pureza:98%
    Forma y color:Solid
    Peso molecular:955.5
  • Neutrophil elastase inhibitor 4


    <p>Neutrophil elastase inhibitor 4 (compound 4f) is a competitive inhibitor of human neutrophil elastase (HNE) with IC50 of 42.30 nM and Ki of 8.04 nM.</p>
    Fórmula:C20H21N3O5
    Forma y color:Solid
    Peso molecular:383.4
  • HCV-IN-41

    CAS:
    <p>HCV-IN-41: potent HCV inhibitor; EC50 - 0.006762 nM (1b), 5.183 nM (2a), 1.365 nM (3a), 142.2 nM (4a); hinders RNA replication.</p>
    Fórmula:C48H56N6O8
    Forma y color:Solid
    Peso molecular:844.99
  • MMP-9/MMP-13 Inhibitor I

    CAS:
    <p>MMP-9/MMP-13 Inhibitor I is a dual inhibitor of MMP-9 and MMP-13 with IC50 of both 0.9 nM.</p>
    Fórmula:C25H25N3O6S
    Forma y color:Solid
    Peso molecular:495.55
  • EP 171

    CAS:
    <p>EP 171 is a potent agonist of TP-receptors.</p>
    Fórmula:C23H29FO5
    Forma y color:Solid
    Peso molecular:404.47
  • Peptide 74

    CAS:
    <p>Peptide 74 is a synthetic peptide. It also inhibits the activated form of this enzyme.</p>
    Fórmula:C62H107N23O20S2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:1558.79
  • Sofosbuvir impurity J

    CAS:
    Sofosbuvir impurity J is an diastereoisomer of Sofosbuvir.Sofosbuvir is an HCV RNA replication inhibitor, with potent anti-hepatitis C virus activity.
    Fórmula:C22H30FN4O8P
    Pureza:98%
    Forma y color:Solid
    Peso molecular:528.47
  • HCV-IN-4

    CAS:
    <p>HCV-IN-4: Potent, oral HCV NS5A inhibitor; effective vs GT1a/b, GT2b, GT3a, Y93H, L31V; EC90s: 3 pM-0.02 nM.</p>
    Fórmula:C52H58FN9O8
    Pureza:98%
    Forma y color:Solid
    Peso molecular:956.07
  • BAY 1217224

    CAS:
    <p>BAY 1217224 is a neutral, non-prodrug Thrombin inhibitor with good oral pharmacokinetics.</p>
    Fórmula:C24H27ClFN3O5
    Forma y color:Solid
    Peso molecular:491.94
  • Relacatib

    CAS:
    <p>Relacatib (SB-462795) is a potent cathepsins K, L, V inhibitor with high affinity (Ki: 41-68 pM) and reduces bone resorption effectively.</p>
    Fórmula:C27H32N4O6S
    Forma y color:Solid
    Peso molecular:540.64