Proteasas / Proteasoma
Los inhibidores de proteasas y proteasomas son compuestos que bloquean la actividad de las proteasas y del proteasoma, que están involucrados en la degradación y renovación de proteínas. Estos inhibidores son vitales para estudiar la regulación de la homeostasis proteica, el control del ciclo celular y la apoptosis. Los inhibidores de proteasas y proteasomas también se utilizan en el tratamiento de enfermedades como el cáncer, donde la degradación anormal de proteínas desempeña un papel en la progresión de la enfermedad. Al inhibir las proteasas o el proteasoma, estos compuestos pueden inducir la muerte celular en células cancerosas y son herramientas esenciales tanto en la investigación básica como en el desarrollo terapéutico. En CymitQuimica, ofrecemos una amplia gama de inhibidores de proteasas y proteasomas de alta calidad para apoyar su investigación en bioquímica, biología celular y desarrollo de fármacos.
Subcategorías de "Proteasas / Proteasoma"
- Acetil-CoA Carboxilasa(35 productos)
- Cisteína proteasa(96 productos)
- DPP-4(20 productos)
- Glutaminasa(40 productos)
- Proteasa del VIH(451 productos)
- PAI-1(25 productos)
- Inhibidores de la proteasa(50 productos)
- Receptor activado por proteasa(53 productos)
- Proteasoma(94 productos)
- Serina proteasa(49 productos)
- p97(14 productos)
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Se han encontrado 1039 productos de "Proteasas / Proteasoma"
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midesteine
CAS:<p>Midesteine (MR-889) is a small molecule neutrophil elastase inhibitor used in the treatment of bronchitis, asthma and chronic lung disease.</p>Fórmula:C12H13NO3S3Pureza:99.52% - 99.98%Forma y color:SolidPeso molecular:315.43PF 00356231
CAS:<p>PF 00356231 is a selectivity inhibitor MMP-12 and can be used in studies about the treatment of emphysema and chronic obstructive pulmonary disease (COPD).</p>Fórmula:C25H20N2O3SPureza:99.35%Forma y color:SolidPeso molecular:428.5Histatin 5
CAS:<p>Histatin 5, a human saliva peptide, blocks MMP-2 and MMP-9 at IC50s of 0.57/0.25 μM and kills fungi.</p>Fórmula:C133H195N51O33Pureza:98%Forma y color:SolidPeso molecular:3036.29EP 171
CAS:<p>EP 171 is a potent agonist of TP-receptors.</p>Fórmula:C23H29FO5Forma y color:SolidPeso molecular:404.47Sofosbuvir impurity K
CAS:<p>Sofosbuvir impurity K is an diastereoisomer of Sofosbuvir.Sofosbuvir is an HCV RNA replication inhibitor, with potent anti-hepatitis C virus activity.</p>Fórmula:C22H29ClN3O9PPureza:98%Forma y color:SolidPeso molecular:545.91Trivalent hydroxyarsinothricn
<p>Trivalent hydroxyarsinothricn (R-AST-OH) is a covalent and irreversible inhibitor of kidney-type glutaminase (KGA). It binds to the glutamine binding site and forms a covalent bond with the cysteine residue at the active site. This compound selectively kills triple-negative breast cancer (TNBC) cells without being cytotoxic to control cell lines. KGA is an enzyme that regulates glutamine metabolism and is associated with tumor malignancy.</p>Fórmula:C4H10AsNO4Peso molecular:210.98258HCV-IN-7 hydrochloride
CAS:HCV-IN-7 hydrochloride: Oral, potent HCV NS5A inhibitor, pan-genotypic, IC50s 3-47 pM, good pharmacokinetics, favorable liver uptake.Fórmula:C40H50Cl2N8O6SPureza:98%Forma y color:SolidPeso molecular:841.85VD2173
CAS:<p>VD2173: a macrocyclic peptide that inhibits HGF serine proteases, matriptase, and hepsin, potentially for lung cancer research.</p>Fórmula:C31H45N9O6SForma y color:SolidPeso molecular:671.81Procizumab
<p>Procizumab is a humanized IgG1 antibody that targets dipeptidyl peptidase 3 (DPP3). It shows potential for investigating sepsis. For the isotype control, refer to HumanIgG1kappa, Isotype Control.</p>Forma y color:Odour LiquidSofigatran
CAS:<p>Sofigatran (MCC-977) is an oral anticoagulant targeting thrombin for cardiovascular research.</p>Fórmula:C24H44N4O4SForma y color:SolidPeso molecular:484.7PSI-353661
CAS:<p>PSI-353661 (GS-558093), inhibits HCV's NS5B polymerase; EC90: 8nM (wild-type), 11nM (S282T); active in human hepatocytes.</p>Fórmula:C24H32FN6O8PForma y color:SolidPeso molecular:582.52Obtusifolin-2-O-glucoside
CAS:<p>Obtusifolin-2-O-glucoside (compound 7), a tyrosinase inhibitor with an IC50 value of 9.2 μM, can be isolated from cassia seed [1].</p>Fórmula:C22H22O10Forma y color:SolidPeso molecular:446.4Ellipyrone B
<p>Ellipyrone B, a γ-pyrone-based macrocyclic polyketide with antihyperglycemic properties, demonstrates inhibitory activity against dipeptidyl peptidase-4 (IC 50</p>Fórmula:C25H38O7Forma y color:SolidPeso molecular:450.57NIM811
CAS:<p>NIM811 is an orally bioavailable dual inhibitor of mitochondrial permeability transition and cyclophilin.</p>Fórmula:C62H111N11O12Pureza:98%Forma y color:SolidPeso molecular:1202.635Cajaninstilbene acid
CAS:<p>Cajaninstilbene acid is a useful organic compound for research related to life sciences. The catalog number is T124035 and the CAS number is 87402-84-4.</p>Fórmula:C21H22O4Forma y color:SolidPeso molecular:338.403GSK2818713
CAS:<p>GSK2818713 is a novel Hepatitis C NS5A replication complex inhibitor.</p>Fórmula:C46H56N8O8Forma y color:SolidPeso molecular:849.002Tyrosinase-IN-36
<p>Tyrosinase-IN-36 is a moderately potent inhibitor of tyrosine, exhibiting an inhibition percentage of 42.75% compared to kojic acid at a concentration of 100 μM and possesses antioxidant activity.</p>Forma y color:Odour SolidZ-FG-NHO-Bz
CAS:<p>Z-FG-NHO-Bz is a selective inhibitor of cathepsin [1].</p>Fórmula:C26H25N3O6Forma y color:SolidPeso molecular:475.49DPP8/9-IN-1
<p>DPP8/9-IN-1 (Compound 16) is a selective covalent inhibitor of dipeptidyl peptidase 8 and 9 (DPP8/9), with IC50 values of 14 nM and 298 nM, respectively. It irreversibly binds to the active site serine (such as S730 in DPP9) through a phosphate ester warhead, blocking substrate binding and inhibiting DPP8/9-mediated protein processing. DPP8/9-IN-1 holds potential for research in cancer and inflammatory diseases.</p>Forma y color:Odour SolidLMP7/LMP2-IN-1
CAS:<p>LMP7/LMP2-IN-1 (Compound 19) is an orally effective inhibitor targeting the immunoproteasome subunits LMP7 and LMP2, with respective IC50 values of 257 and 10 nM. This compound reduces the production of antibodies and downregulates the B cells in the germinal centers of the spleen and plasma cells in NP-OVA immunized mice. It has potential applications in the study of autoimmune diseases.</p>Fórmula:C16H27BN4O3Forma y color:SoildPeso molecular:334.22
