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Proteasas / Proteasoma

Proteasas / Proteasoma

Los inhibidores de proteasas y proteasomas son compuestos que bloquean la actividad de las proteasas y del proteasoma, que están involucrados en la degradación y renovación de proteínas. Estos inhibidores son vitales para estudiar la regulación de la homeostasis proteica, el control del ciclo celular y la apoptosis. Los inhibidores de proteasas y proteasomas también se utilizan en el tratamiento de enfermedades como el cáncer, donde la degradación anormal de proteínas desempeña un papel en la progresión de la enfermedad. Al inhibir las proteasas o el proteasoma, estos compuestos pueden inducir la muerte celular en células cancerosas y son herramientas esenciales tanto en la investigación básica como en el desarrollo terapéutico. En CymitQuimica, ofrecemos una amplia gama de inhibidores de proteasas y proteasomas de alta calidad para apoyar su investigación en bioquímica, biología celular y desarrollo de fármacos.

Subcategorías de "Proteasas / Proteasoma"

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Se han encontrado 1044 productos de "Proteasas / Proteasoma"

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  • Pentosan Polysulfate

    CAS:
    <p>Pentosan Polysulfate: anti-HIV, anti-inflammatory, supports cartilage, treats interstitial cystitis.</p>
    Pureza:98%
    Forma y color:Solid
    Peso molecular:N/A
  • MMP-3 Inhibitor acetate


    <p>MMP-3 Inhibitor acetate is a cell-permeable and potent inhibitor of human MMP-3.</p>
    Fórmula:C29H50N10O11S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:746.83
  • BMS-767778

    CAS:
    <p>BMS-767778, a DPP-4 inhibitor, is used potentially for the treatment of type 2 diabetes.</p>
    Fórmula:C19H20Cl2N4O2
    Forma y color:Solid
    Peso molecular:407.29
  • Tyrosinase-IN-34


    <p>Tyrosinase-IN-34 (compound 5a), a human tyrosinase inhibitor (IC 50: 3.5 μM), shows promise in regulating melanogenesis and pigmentation.</p>
    Fórmula:C19H14BrClN4O
    Forma y color:Solid
    Peso molecular:429.7
  • α 1(I) Collagen (614-639), human

    CAS:
    <p>This is a peptide inhibitor of collagen fibrillar matrix assembly.</p>
    Fórmula:C134H189N37O39
    Pureza:98%
    Forma y color:Solid
    Peso molecular:2942.16
  • Apovincamine

    CAS:
    <p>Apovincamine is a vinca alkaloid and a chemical precursor of Vinpocetine, which is a derivative of Vincamine with vasodilating activity.</p>
    Fórmula:C21H24N2O2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:336.44
  • Nitidanin


    <p>Nitidanin is a useful organic compound for research related to life sciences and the catalog number is T125599.</p>
    Fórmula:C21H24O8
    Forma y color:Solid
    Peso molecular:404.415
  • NVP-DPP728 dihydrochloride

    CAS:
    <p>NVP-DPP728 dihydrochloride is a potent, selective DPP-IV inhibitor with a Ki of 11 nM, useful in diabetes research.</p>
    Fórmula:C15H20Cl2N6O
    Forma y color:Solid
    Peso molecular:371.27
  • RJS308


    <p>RJS308 is a PROTAC degrader of cyclosporin A (cyclosporin A) with a DC50 of 284 nM. It exhibits antiviral activity by inhibiting the replication of HIV-1 and HCV. (Pink: ligand for target protein CypA ligand-2; Black: linker; Blue: ligand for E3 ligase VHL (S,R,S)-AHPC-Me)</p>
    Fórmula:C63H75N13O11S
    Forma y color:Solid
    Peso molecular:1222.42
  • Stevia Powder


    <p>Stevia Powder, a natural sweetener, possesses antioxidant properties. It regulates antifibrotic pathways in cirrhotic rats, demonstrated by a reduction in hepatic stellate cells and decreased expression of matrix metalloproteinases MMP2 and MMP13. Furthermore, it increases the antifibrotic molecule Smad7, which helps prevent the elevation of serum necrosis and bile retention markers, thereby inhibiting the progression of liver fibrosis.</p>
    Forma y color:Odour Solid
  • PR 39 (porcine) acetate


    <p>PR 39 (porcine) acetate is a noncompetitive, reversible and allosteric proteasome inhibitor.</p>
    Pureza:98%
    Forma y color:Liquid
    Peso molecular:N/A
  • 6-Acetylnimbandiol

    CAS:
    <p>6-Acetylnimbandiol, a non-toxic agent, inhibits tyrosinase (IC50=69.85 μM), melanin, and MITF; useful in melanoma studies.</p>
    Fórmula:C28H34O8
    Forma y color:Solid
    Peso molecular:498.56
  • Isoleucylvaline

    CAS:
    <p>Isoleucylvaline is a dipeptide.</p>
    Fórmula:C11H22N2O3
    Forma y color:Solid
    Peso molecular:230.30
  • PPACK II

    CAS:
    <p>PPACK II is an irreversible and specific glandular and plasma kallikreins inhibitor [1] .</p>
    Fórmula:C25H33ClN6O3
    Forma y color:Solid
    Peso molecular:501.02
  • L 659286

    CAS:
    <p>L 659286 is one kind of cephalosporin derivative.</p>
    Fórmula:C17H21N5O7S2
    Forma y color:Solid
    Peso molecular:471.51
  • Pseudostellarin G

    CAS:
    <p>Pseudostellarin G, a naturally occurring cyclo-octapeptide, exhibits inhibitory activity against tyrosinase and suppresses melanin production.</p>
    Fórmula:C42H56N8O9
    Forma y color:Solid
    Peso molecular:816.94
  • Fotagliptin

    CAS:
    <p>Fotagliptin is a dipeptidyl peptidase IV inhibitor.</p>
    Fórmula:C17H19FN6O
    Forma y color:Solid
    Peso molecular:342.37
  • Ellipyrone A


    <p>Ellipyrone A: γ-pyrone macrocycle, inhibits DPP-4 (IC50=0.35mM), α-glucosidase (IC50=0.74mM), α-amylase (IC50=0.59mM).</p>
    Fórmula:C25H34O8
    Forma y color:Solid
    Peso molecular:462.53
  • PM 102

    CAS:
    <p>Peptide that reverses the anticoagulant effect of heparin. Potently binds heparin (Kd = 36 nM in vitro).</p>
    Fórmula:C235H425N111O64
    Pureza:98%
    Forma y color:Solid
    Peso molecular:5830
  • WYRGRL

    CAS:
    <p>WYRGRL is a peptide that targets collagen II α1 (collagen II α1) through binding interaction. This short chondro-targeting peptide sequence enhances the targeting efficiency of peptide-functionalized nanoplatforms for cartilage in vivo, increasing it by approximately 72 times.</p>
    Fórmula:C40H59N13O8
    Forma y color:Solid
    Peso molecular:849.98