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Proteasas / Proteasoma

Proteasas / Proteasoma

Los inhibidores de proteasas y proteasomas son compuestos que bloquean la actividad de las proteasas y del proteasoma, que están involucrados en la degradación y renovación de proteínas. Estos inhibidores son vitales para estudiar la regulación de la homeostasis proteica, el control del ciclo celular y la apoptosis. Los inhibidores de proteasas y proteasomas también se utilizan en el tratamiento de enfermedades como el cáncer, donde la degradación anormal de proteínas desempeña un papel en la progresión de la enfermedad. Al inhibir las proteasas o el proteasoma, estos compuestos pueden inducir la muerte celular en células cancerosas y son herramientas esenciales tanto en la investigación básica como en el desarrollo terapéutico. En CymitQuimica, ofrecemos una amplia gama de inhibidores de proteasas y proteasomas de alta calidad para apoyar su investigación en bioquímica, biología celular y desarrollo de fármacos.

Subcategorías de "Proteasas / Proteasoma"

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Se han encontrado 1044 productos de "Proteasas / Proteasoma"

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  • Ivachtin

    CAS:
    <p>Ivachtin (Caspase-3 Inhibitor VII) is a nonpeptide, noncompetitive and reversibl caspase-3 inhibitor(IC50 = 23 nM) and is a modest inhibitor of the remaining</p>
    Fórmula:C20H21N3O7S
    Pureza:99.74%
    Forma y color:Solid
    Peso molecular:447.46
  • TCH-165

    CAS:
    <p>TCH-165 boosts 20S proteasome levels, enhancing IDP breakdown.</p>
    Fórmula:C39H37N3O3
    Pureza:98.2% - 98.75%
    Forma y color:Solid
    Peso molecular:595.73
  • Daclatasvir dihydrochloride

    CAS:
    <p>Daclatasvir dihydrochloride is an oral antiviral that treats chronic hepatitis C by inhibiting HCV's NS5A; rare liver enzyme elevation, seldom causes jaundice.</p>
    Fórmula:C40H52Cl2N8O6
    Pureza:99.67%
    Forma y color:Solid
    Peso molecular:811.8
  • Bemnifosbuvir hemisulfate

    CAS:
    <p>Bemnifosbuvir hemisulfate (AT-527) is a potent inhibitor of HCV virus replication.</p>
    Fórmula:C48H68F2N14O18P2S
    Pureza:99.98%
    Forma y color:Solid
    Peso molecular:1261.15
  • Lusutrombopag

    CAS:
    <p>Lusutrombopag (Mulpleta) is an orally bioavailable, small molecule thrombopoietin (TPO) receptor agonist for chronic liver disease (CLD) patients with</p>
    Fórmula:C29H32Cl2N2O5S
    Pureza:99.96%
    Forma y color:Solid
    Peso molecular:591.55
  • TAPI-1 trifluoroacetate (163847-77-6(free base))


    <p>TAPI-1 is an ADAM17/TACE inhibitor, which blocks shedding of cytokine receptors.</p>
    Fórmula:C28H38F3N5O7
    Pureza:98.06%
    Forma y color:Solid
    Peso molecular:613.62
  • Ixazomib citrate

    CAS:
    <p>Ixazomib citrate (MLN9708), a prodrug of Ixazomib (MMLN-2238), is an oral 2nd-gen proteasome inhibitor with anti-cancer potential (IC50: 3.4 nM).</p>
    Fórmula:C20H23BCl2N2O9
    Pureza:98.37% - >99.99%
    Forma y color:Solid
    Peso molecular:517.12
  • Velpatasvir

    CAS:
    <p>Velpatasvir (GS-5816), also known as GS-5816, is a potent and selective Hepatitis C virus NS5A inhibitor.</p>
    Fórmula:C49H54N8O8
    Pureza:99.17% - 99.83%
    Forma y color:Solid
    Peso molecular:883
  • Etravirine

    CAS:
    <p>Etravirine (R165335) is a diarylpyrimidine non-nucleoside reverse transcriptase inhibitor.</p>
    Fórmula:C20H15BrN6O
    Pureza:97.61% - 99.74%
    Forma y color:White To Off-White Solid
    Peso molecular:435.28
  • Letermovir

    CAS:
    <p>Letermovir (AIC246) (AIC246) is a novel anti-CMV compound (EC50: about 5 nM in fibroblast cells). It targets the pUL56 subunit of the viral terminase complex.</p>
    Fórmula:C29H28F4N4O4
    Pureza:99.85% - 99.87%
    Forma y color:Solid
    Peso molecular:572.55
  • CA-074 methyl ester

    CAS:
    <p>CA-074 methyl ester (Cathepsin B Inhibitor IV) is a selective inhibitor of Cathepsin B (IC50=36.3 nM). neuroprotective effect. High-Quality, Low-Cost!</p>
    Fórmula:C19H31N3O6
    Pureza:97.26% - 99.58%
    Forma y color:Solid
    Peso molecular:397.47
  • Dabigatran Etexilate Mesylate

    CAS:
    <p>Dabigatran Etexilate Mesylate (BIBR 1048MS) is the orally active prodrug of dabigatran. Dabigatran is a reversible and selective, direct thrombin inhibitor.</p>
    Fórmula:C34H41N7O5·CH4O3S
    Pureza:99.91%
    Forma y color:Solid
    Peso molecular:723.84
  • Peptide T acetate(106362-32-7 free base)


    <p>Peptide T acetate is an octapeptide from the V2 region of HIV-1 gp120.</p>
    Fórmula:C37H59N9O18
    Pureza:99.47%
    Forma y color:Solid
    Peso molecular:917.91
  • Bemnifosbuvir

    CAS:
    <p>Bemnifosbuvir (AT-511) is a novel phosphoramidate prodrug of 2'-fluoro-2'-C-methylguanosine-5'-monophosphate that has potent in vitro activity against HCV.</p>
    Fórmula:C24H33FN7O7P
    Pureza:99.35% - 99.54%
    Forma y color:Solid
    Peso molecular:581.53
  • PTACH

    CAS:
    <p>PTACH (Cpd 51) (NCH-51) is a SAHA-based inhibitor of human HDAC. It can potently inhibit the growth of various human Y cells (EC50: 1 to 10 μM).</p>
    Fórmula:C20H26N2O2S2
    Pureza:87.44% - 99.74%
    Forma y color:Solid
    Peso molecular:390.56
  • (S,S)-TAPI-1

    CAS:
    <p>"(S,S)-TAPI-1, an isomer of TAPI-1, inhibits MMPs and TACE (ADAM17), reducing cell surface protein shedding."</p>
    Fórmula:C26H37N5O5
    Forma y color:Solid
    Peso molecular:499.6
  • Darunavir

    CAS:
    <p>Darunavir (TMC114) is an HIV PROTEASE INHIBITOR that is used in the treatment of AIDS and HIV INFECTIONS.</p>
    Fórmula:C27H37N3O7S
    Pureza:99.67% - 99.76%
    Forma y color:White Amorphous Solid
    Peso molecular:547.66
  • Coblopasvir dihydrochloride

    CAS:
    <p>Coblopasvir dihydrochloride can be used to study chronic HCV infection and is a pan-genotypic nonstructural protein 5A (NS5A) inhibitor.</p>
    Fórmula:C41H52Cl2N8O8
    Pureza:99.33%
    Forma y color:Solid
    Peso molecular:855.81
  • Daclatasvir

    CAS:
    <p>Daclatasvir (EBP 883/BMS-790052) is a potent HCV NS5A inhibitor with EC50 9-50 pM across various genotypes. Phase 3.</p>
    Fórmula:C40H50N8O6
    Pureza:99.81%
    Forma y color:Solid
    Peso molecular:738.88
  • Asunaprevir

    CAS:
    <p>Asunaprevir (BMS-650032) is an effective hepatitis C virus (HCV) NS3 protease inhibitor.</p>
    Fórmula:C35H46ClN5O9S
    Pureza:99.34% - 99.8%
    Forma y color:Solid
    Peso molecular:748.29