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Proteasas / Proteasoma

Proteasas / Proteasoma

Los inhibidores de proteasas y proteasomas son compuestos que bloquean la actividad de las proteasas y del proteasoma, que están involucrados en la degradación y renovación de proteínas. Estos inhibidores son vitales para estudiar la regulación de la homeostasis proteica, el control del ciclo celular y la apoptosis. Los inhibidores de proteasas y proteasomas también se utilizan en el tratamiento de enfermedades como el cáncer, donde la degradación anormal de proteínas desempeña un papel en la progresión de la enfermedad. Al inhibir las proteasas o el proteasoma, estos compuestos pueden inducir la muerte celular en células cancerosas y son herramientas esenciales tanto en la investigación básica como en el desarrollo terapéutico. En CymitQuimica, ofrecemos una amplia gama de inhibidores de proteasas y proteasomas de alta calidad para apoyar su investigación en bioquímica, biología celular y desarrollo de fármacos.

Subcategorías de "Proteasas / Proteasoma"

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Se han encontrado 1044 productos de "Proteasas / Proteasoma"

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  • TAPI-1 trifluoroacetate (163847-77-6(free base))


    TAPI-1 is an ADAM17/TACE inhibitor, which blocks shedding of cytokine receptors.
    Fórmula:C28H38F3N5O7
    Pureza:98.06%
    Forma y color:Solid
    Peso molecular:613.62
  • Elbasvir

    CAS:
    <p>Elbasvir (MK-8742) is an NS5A inhibitor developed for chronic HCV treatment.</p>
    Fórmula:C49H55N9O7
    Pureza:98.95% - 99.85%
    Forma y color:Solid
    Peso molecular:882.02
  • Daclatasvir dihydrochloride

    CAS:
    <p>Daclatasvir dihydrochloride is an oral antiviral that treats chronic hepatitis C by inhibiting HCV's NS5A; rare liver enzyme elevation, seldom causes jaundice.</p>
    Fórmula:C40H52Cl2N8O6
    Pureza:99.67%
    Forma y color:Solid
    Peso molecular:811.8
  • Dolutegravir

    CAS:
    <p>Dolutegravir (GSK1349572), HIV integrase inhibitor with IC50 of 2.7 nM, partly effective against some raltegravir-resistant HIV strains.</p>
    Fórmula:C20H19F2N3O5
    Pureza:98.97% - 99.75%
    Forma y color:White To Pale Yellow Solid
    Peso molecular:419.38
  • Y-29794 Tosylate

    CAS:
    <p>Y-29794 Tosylate (Y-29794) is an orally active, effective, and specific non-peptide-prolyl endopeptidase (PPCE) inhibitor.</p>
    Fórmula:C30H42N2O4S3
    Pureza:99.86%
    Forma y color:Solid
    Peso molecular:590.86
  • Tegobuvir

    CAS:
    <p>Tegobuvir (GS 333126) is a specific and covalent HCV NS5B polymerase inhibitor.</p>
    Fórmula:C25H14F7N5
    Pureza:99.21%
    Forma y color:Solid
    Peso molecular:517.4
  • Voxilaprevir

    CAS:
    <p>Voxilaprevir is an inhibitor of hepatitis C virus (HCV) nonstructural (NS) protein 3/4A protease.</p>
    Fórmula:C40H52F4N6O9S
    Pureza:99.83% - 99.93%
    Forma y color:Solid
    Peso molecular:868.93
  • Ixazomib citrate

    CAS:
    <p>Ixazomib citrate (MLN9708), a prodrug of Ixazomib (MMLN-2238), is an oral 2nd-gen proteasome inhibitor with anti-cancer potential (IC50: 3.4 nM).</p>
    Fórmula:C20H23BCl2N2O9
    Pureza:98.37% - >99.99%
    Forma y color:Solid
    Peso molecular:517.12
  • Grazoprevir

    CAS:
    <p>Grazoprevir (MK-5172) is a protease inhibitor targeting hepatitis C virus NS3/4A used for treating chronic HCV genotypes 1 or 4 infections. Cost-effective and quality-assured.</p>
    Fórmula:C38H50N6O9S
    Pureza:99.36% - >99.99%
    Forma y color:Solid
    Peso molecular:766.9
  • Ac-DEVD-AMC

    CAS:
    <p>Ac-DEVD-AMC (AC-ASP-MET-GLN-ASP-7-AMINO-4-METHYLCOUMARIN) is the substrate of Caspase-3 .</p>
    Fórmula:C30H37N5O13
    Pureza:98.20%
    Forma y color:White Powder
    Peso molecular:675.64
  • 4-Phenoxybenzylamine

    CAS:
    <p>4-Phenoxybenzylamine inhibits the function of the NS3 protein by stabilizing an inactive conformation with an IC50 of about 500 μM against HCV NS3/4a .</p>
    Fórmula:C13H13NO
    Pureza:97.26%
    Forma y color:Solid
    Peso molecular:199.25
  • Lersivirine

    CAS:
    <p>Lersivirine (UK-453061)(UK 453061) is a second-generation non-nucleoside reverse transcriptase inhibitor (NNRTI) under development for HIV infection therapy.</p>
    Fórmula:C17H18N4O2
    Pureza:98.01%
    Forma y color:Solid
    Peso molecular:310.35
  • Dolutegravir sodium

    CAS:
    <p>Dolutegravir sodium (GSK-1349572A) salt(DTG; GSK1349572) is an HIV integrase inhibitor(IC50: 2.7 nM), modest activity against raltegravir-resistant signature</p>
    Fórmula:C20H18F2N3NaO5
    Pureza:98% - 99.46%
    Forma y color:Solid
    Peso molecular:441.36
  • CA-074 methyl ester

    CAS:
    <p>CA-074 methyl ester (Cathepsin B Inhibitor IV) is a selective inhibitor of Cathepsin B (IC50=36.3 nM). neuroprotective effect. High-Quality, Low-Cost!</p>
    Fórmula:C19H31N3O6
    Pureza:97.26% - 99.58%
    Forma y color:Solid
    Peso molecular:397.47
  • Peptide T acetate(106362-32-7 free base)


    <p>Peptide T acetate is an octapeptide from the V2 region of HIV-1 gp120.</p>
    Fórmula:C37H59N9O18
    Pureza:99.47%
    Forma y color:Solid
    Peso molecular:917.91
  • Daclatasvir

    CAS:
    <p>Daclatasvir (EBP 883/BMS-790052) is a potent HCV NS5A inhibitor with EC50 9-50 pM across various genotypes. Phase 3.</p>
    Fórmula:C40H50N8O6
    Pureza:99.81%
    Forma y color:Solid
    Peso molecular:738.88
  • PTACH

    CAS:
    PTACH (Cpd 51) (NCH-51) is a SAHA-based inhibitor of human HDAC. It can potently inhibit the growth of various human Y cells (EC50: 1 to 10 μM).
    Fórmula:C20H26N2O2S2
    Pureza:87.44% - 99.74%
    Forma y color:Solid
    Peso molecular:390.56
  • Marimastat

    CAS:
    <p>Marimastat (BB2516) (BB-2516) is a potent, broad spectrum matrix metalloprotease (MMP) inhibitor.</p>
    Fórmula:C15H29N3O5
    Pureza:97.46% - 98.11%
    Forma y color:Solid
    Peso molecular:331.41
  • Letermovir

    CAS:
    <p>Letermovir (AIC246) (AIC246) is a novel anti-CMV compound (EC50: about 5 nM in fibroblast cells). It targets the pUL56 subunit of the viral terminase complex.</p>
    Fórmula:C29H28F4N4O4
    Pureza:99.85% - 99.87%
    Forma y color:Solid
    Peso molecular:572.55
  • (R)-MG-132

    CAS:
    <p>(R)-MG-132 (Z-Leu-D-leu-leu-al) is the enantiomer of MG-132. (R)-MG-132 stereoisomer is a more potent proteasome inhibitor than MG-132.</p>
    Fórmula:C26H41N3O5
    Pureza:98.45%
    Forma y color:Solid
    Peso molecular:475.62