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Proteasas / Proteasoma

Proteasas / Proteasoma

Los inhibidores de proteasas y proteasomas son compuestos que bloquean la actividad de las proteasas y del proteasoma, que están involucrados en la degradación y renovación de proteínas. Estos inhibidores son vitales para estudiar la regulación de la homeostasis proteica, el control del ciclo celular y la apoptosis. Los inhibidores de proteasas y proteasomas también se utilizan en el tratamiento de enfermedades como el cáncer, donde la degradación anormal de proteínas desempeña un papel en la progresión de la enfermedad. Al inhibir las proteasas o el proteasoma, estos compuestos pueden inducir la muerte celular en células cancerosas y son herramientas esenciales tanto en la investigación básica como en el desarrollo terapéutico. En CymitQuimica, ofrecemos una amplia gama de inhibidores de proteasas y proteasomas de alta calidad para apoyar su investigación en bioquímica, biología celular y desarrollo de fármacos.

Subcategorías de "Proteasas / Proteasoma"

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Se han encontrado 1039 productos de "Proteasas / Proteasoma"

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  • Avatrombopag

    CAS:
    <p>Avatrombopag (YM477) is a new oral thrombopoietin (TPO) receptor agonist, activating TPO receptor and increasing megakaryocytic proliferation/differentiation</p>
    Fórmula:C29H34Cl2N6O3S2
    Pureza:99.01% - 99.63%
    Forma y color:Solid
    Peso molecular:649.65
  • KGP94

    CAS:
    <p>KGP94 is a potent, selective, and competitive inhibitor of the lysosomal endopeptidase enzyme.</p>
    Fórmula:C14H12BrN3OS
    Pureza:99.6%
    Forma y color:Solid
    Peso molecular:350.23
  • SB-734117

    CAS:
    <p>SB-734117 inhibits productive replication of several HCMV strains.</p>
    Fórmula:C14H16N6O
    Pureza:99.72%
    Forma y color:Solid
    Peso molecular:284.32
  • HZ-1157

    CAS:
    HZ-1157 (DHFR-inhibitor) is a hepatitis C virus (HCV) inhibitor with inhibitory activities toward HCV NS3/4A protease.
    Fórmula:C12H16N4O
    Pureza:98.23%
    Forma y color:Solid
    Peso molecular:232.28
  • Enfuvirtide acetate

    CAS:
    <p>Enfuvirtide acetate salt is a linear synthetic peptide made of 36 amino acids. It has an acetylated N-terminus and a carboxamide C-terminus.</p>
    Fórmula:C206H305N51O66
    Pureza:99.34%
    Forma y color:Solid
    Peso molecular:4552
  • Z-YVAD-FMK

    CAS:
    <p>AA-Z-YVAD-FMK is a Irreversible caspase-1 inhibitor,with anti-inflammatory and anti-tumor activities.</p>
    Fórmula:C31H39FN4O9
    Pureza:98.00%
    Forma y color:Solid
    Peso molecular:630.66
  • Ixazomib

    CAS:
    <p>Ixazomib (MLN2238) is a boron-based peptide proteasome inhibitor targeting β5 site (IC50: 3.4 nM), also affecting β1 and β2 sites.</p>
    Fórmula:C14H19BCl2N2O4
    Pureza:98% - 98.92%
    Forma y color:Solid
    Peso molecular:361.03
  • Azvudine

    CAS:
    <p>Azvudine (FNC) is a powerful NRTI effective against HIV, HBV, HCV, and resistant strains.</p>
    Fórmula:C9H11FN6O4
    Pureza:99.76% - >99.99%
    Forma y color:Solid
    Peso molecular:286.22
  • MMP-9-IN-1

    CAS:
    <p>MMP-9-IN-1 is an inhibitor of specific matrix metalloproteinase-9 (MMP-9).</p>
    Fórmula:C16H17F2N3O3S
    Pureza:99.21% - 99.86%
    Forma y color:Solid
    Peso molecular:369.39
  • GW280264X

    CAS:
    GW280264X (Carbamic acid) is an inhibitor of ADAM17 .
    Fórmula:C28H41N5O6S
    Pureza:99.51%
    Forma y color:Solid
    Peso molecular:575.72
  • Coblopasvir dihydrochloride

    CAS:
    <p>Coblopasvir dihydrochloride can be used to study chronic HCV infection and is a pan-genotypic nonstructural protein 5A (NS5A) inhibitor.</p>
    Fórmula:C41H52Cl2N8O8
    Pureza:99.33%
    Forma y color:Solid
    Peso molecular:855.81
  • 2,4-Dioxaspiro(5.5)undec-8-ene, 3-(2-furanyl)-

    CAS:
    <p>2,4-Dioxaspiro(5.5)undec-8-ene, 3-(2-furanyl)- (Ulinastatin) ,as an urinary trypsin inhibitor (UTI), is a glycoprotein that is isolated from healthy human urine</p>
    Fórmula:C13H16O3
    Pureza:99.53% - 99.81%
    Forma y color:Solid
    Peso molecular:220.26
  • Glutaminase C-IN-1

    CAS:
    <p>Glutaminase C-IN-1 (Compound 968) is a Glutaminase C allosteric inhibitor.</p>
    Fórmula:C27H27BrN2O
    Pureza:99.68% - >99.99%
    Forma y color:Solid
    Peso molecular:475.42
  • Saxagliptin

    CAS:
    <p>Saxagliptin (BMS-477118) is a selective and reversible DPP4 inhibitor with IC50 of 26 nM.</p>
    Fórmula:C18H25N3O2
    Pureza:99.17% - 99.95%
    Forma y color:Solid
    Peso molecular:315.41
  • Samatasvir

    CAS:
    <p>Samatasvir (ATOLIHZIXHZSBA-BTSKBWHGSA-N) is a pan-genotypic inhibitor of the HCV non-structural protein 5A.</p>
    Fórmula:C47H48N8O6S2
    Pureza:98.03%
    Forma y color:Solid
    Peso molecular:885.06
  • RO8191

    CAS:
    <p>RO8191 (CDM-3008) (CDM-3008) is an agonist of interferon (IFN) receptor.</p>
    Fórmula:C14H5F6N5O
    Pureza:98% - 98.85%
    Forma y color:Solid
    Peso molecular:373.21
  • 4-Phenoxybenzylamine

    CAS:
    <p>4-Phenoxybenzylamine inhibits the function of the NS3 protein by stabilizing an inactive conformation with an IC50 of about 500 μM against HCV NS3/4a .</p>
    Fórmula:C13H13NO
    Pureza:97.26%
    Forma y color:Solid
    Peso molecular:199.25
  • Simeprevir

    CAS:
    <p>Simeprevir (TMC435) is a potent HCV NS3/4A protease inhibitor, and inhibits HCV replication with EC50 of 8 nM.</p>
    Fórmula:C38H47N5O7S2
    Pureza:99.45% - 99.92%
    Forma y color:Solid
    Peso molecular:749.94
  • Ombitasvir

    CAS:
    <p>Ombitasvir (ABT-267) inhibits HCV protein NS5A, effective orally, EC50: 0.82-19.3 pM (genotypes 1-5), 366 pM (genotype 6a).</p>
    Fórmula:C50H67N7O8
    Pureza:97.27% - 99.56%
    Forma y color:Solid
    Peso molecular:894.11
  • Proteasome inhibitor IX

    CAS:
    <p>Proteasome inhibitor IX (PS-IX) is an inhibitor of chymotrypsin-like activity of the 20S proteasome (IC50 ~1 μM).</p>
    Fórmula:C20H21B2NO5
    Pureza:99.77%
    Forma y color:Solid
    Peso molecular:377.01