Proteasas / Proteasoma
Los inhibidores de proteasas y proteasomas son compuestos que bloquean la actividad de las proteasas y del proteasoma, que están involucrados en la degradación y renovación de proteínas. Estos inhibidores son vitales para estudiar la regulación de la homeostasis proteica, el control del ciclo celular y la apoptosis. Los inhibidores de proteasas y proteasomas también se utilizan en el tratamiento de enfermedades como el cáncer, donde la degradación anormal de proteínas desempeña un papel en la progresión de la enfermedad. Al inhibir las proteasas o el proteasoma, estos compuestos pueden inducir la muerte celular en células cancerosas y son herramientas esenciales tanto en la investigación básica como en el desarrollo terapéutico. En CymitQuimica, ofrecemos una amplia gama de inhibidores de proteasas y proteasomas de alta calidad para apoyar su investigación en bioquímica, biología celular y desarrollo de fármacos.
Subcategorías de "Proteasas / Proteasoma"
- Acetil-CoA Carboxilasa(35 productos)
- Cisteína proteasa(107 productos)
- DPP-4(20 productos)
- Glutaminasa(42 productos)
- Proteasa del VIH(489 productos)
- PAI-1(26 productos)
- Inhibidores de la proteasa(50 productos)
- Receptor activado por proteasa(53 productos)
- Proteasoma(95 productos)
- Serina proteasa(56 productos)
- p97(15 productos)
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Se han encontrado 1085 productos de "Proteasas / Proteasoma"
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MMP-7-IN-3
CAS:<p>MMP-7-IN-3 (compound 15) is a potent and selective MMP-7 inhibitor, inhibiting renal fibrosis in a unilateral ureteral obstruction mouse model.</p>Fórmula:C34H43ClF3N7O9SPureza:99.915%Forma y color:SolidPeso molecular:818.26HIV-1 protease-IN-11
CAS:HIV-1 protease-IN-11 (compound 34a), an HIV-1 protease inhibitor, demonstrates potent inhibition with an IC50 of 0.41 nM and maintains substantial efficacyFórmula:C26H37N3O5SPureza:98%Forma y color:SolidPeso molecular:503.65HIV-1 protease-IN-8
CAS:HIV-1 protease-IN-8 (compound 34b) is a potent inhibitor of the HIV-1 protease enzyme, exhibiting an IC50 of 0.32 nM.Fórmula:C25H35N3O5SPureza:98%Forma y color:SolidPeso molecular:489.63HIV-1 protease-IN-7
CAS:HIV-1 protease-IN-7 (compound 16) is an orally active inhibitor of HIV-1 protease, exhibiting an IC50 of 3.52 nM and an EC50 of 37 nM [1].Fórmula:C68H104N10O12SPureza:98%Forma y color:SolidPeso molecular:1285.68HIV-1 protease-IN-12
CAS:<p>HIV-1 protease-IN-12 (compound 35b) serves as a potent inhibitor of HIV-1 protease, exhibiting an IC50 value of 0.51 nM, and demonstrates efficacy against drug-</p>Fórmula:C25H35N3O5SPureza:98%Forma y color:SolidPeso molecular:489.63NS5A-IN-2
CAS:NS5A-IN-2, a potent inhibitor, is highly effective against HCV 1b and shows increased activity for GT 3a with good metabolic stability.Fórmula:C46H45N7O7Pureza:98%Forma y color:SolidPeso molecular:807.89NCI-B16
CAS:<p>NCI-B16 is a small-molecule RNA binder that inhibits HCV (hepatitis C virus) replication [1].</p>Fórmula:C27H26N8O4Forma y color:SolidPeso molecular:526.55HIV-1 protease-IN-9
CAS:HIV-1 protease-IN-9 (compound 5b), a potent HIV-1 protease inhibitor, exhibits strong antiviral efficacy with a dissociation constant (K_i) of 0.028 nM and aFórmula:C37H41N7O4SPureza:98%Forma y color:SolidPeso molecular:679.83TP0556351
CAS:TP0556351: potent MMP2 inhibitor with 0.2 nM IC50, reduces collagen in pulmonary fibrosis mice.Fórmula:C50H70N10O16Pureza:98%Forma y color:SolidPeso molecular:1067.15MK-3281
CAS:MK-3281: Oral, potent HCV NS5B inhibitor with promising properties and efficacy in replication trials, suitable for clinical use.Fórmula:C29H37N3O3Forma y color:SolidPeso molecular:475.62SQ 32056
CAS:SQ 32056 is a cathepsin E inhibitor.Fórmula:C37H56N4O5Pureza:98%Forma y color:SolidPeso molecular:636.86Beclabuvir HCl
CAS:<p>Beclabuvir (BMS-791325) is an HCV inhibitor targeting NS5B polymerase with sub-28 nM potency for genotypes 1, 3, 4, 5.</p>Fórmula:C36H46ClN5O5SForma y color:SolidPeso molecular:696.3Cipemastat
CAS:Cipemastat is a competitive inhibitor of human collagenases 1, 2, and 3 (Kis: 3.0, 4.4, and 3.4 nM).Fórmula:C22H36N4O5Pureza:98%Forma y color:SolidPeso molecular:436.55Paltimatrectinib
CAS:Paltimatrectinib (PBI-200) is a tyrosine kinase inhibitor with anticancer activity, and is used in the study of bladder, breast, and colorectal cancers.Fórmula:C20H15F5N6Pureza:99.96%Forma y color:SolidPeso molecular:434.37Mergetpa
CAS:Mergetpa, a carboxypeptidase inhibitor, impedes the conversion of kinins and B2 receptor antagonists into metabolites devoid of the C-terminal arginine [1].Fórmula:C7H15N3O2S2Pureza:98%Forma y color:SolidPeso molecular:237.34Collagen proline hydroxylase inhibitor
CAS:<p>Collagen proline hydroxylase inhibitor is an inhibitor collagen proline hydroxylase and useful for antifibrotic proliferative agents.</p>Fórmula:C18H18N4O4Pureza:98%Forma y color:SolidPeso molecular:354.36LU-002i
CAS:<p>LU-002i is a selective inhibitor targeting the human proteasome subunits β2c and β2i, demonstrating an inhibitory concentration (IC50) of 220 nM for β2i [1].</p>Fórmula:C35H52N4O7Pureza:98%Forma y color:SolidPeso molecular:640.81Z-PDLDA-NHOH
CAS:Z-PDLDA-NHOH is a potent, specific vertebrate collagenase inhibitor [1].Fórmula:C22H32N4O6Forma y color:SolidPeso molecular:448.51BMS-189664 HCl
CAS:BMS-189664 HCl is a selective and orally active thrombin active site inhibitor.Fórmula:C22H35ClN6O4SPureza:98%Forma y color:SolidPeso molecular:515.07LM-030
CAS:LM-030, also known as BPR277, is a novel inhibitor of kallikrein-related peptidase 7 (KLK7) and epidermal elastase 2 (ELA2).Fórmula:C46H72N8O12Forma y color:SolidPeso molecular:929.11
