Proteasas / Proteasoma
Los inhibidores de proteasas y proteasomas son compuestos que bloquean la actividad de las proteasas y del proteasoma, que están involucrados en la degradación y renovación de proteínas. Estos inhibidores son vitales para estudiar la regulación de la homeostasis proteica, el control del ciclo celular y la apoptosis. Los inhibidores de proteasas y proteasomas también se utilizan en el tratamiento de enfermedades como el cáncer, donde la degradación anormal de proteínas desempeña un papel en la progresión de la enfermedad. Al inhibir las proteasas o el proteasoma, estos compuestos pueden inducir la muerte celular en células cancerosas y son herramientas esenciales tanto en la investigación básica como en el desarrollo terapéutico. En CymitQuimica, ofrecemos una amplia gama de inhibidores de proteasas y proteasomas de alta calidad para apoyar su investigación en bioquímica, biología celular y desarrollo de fármacos.
Subcategorías de "Proteasas / Proteasoma"
- Acetil-CoA Carboxilasa(34 productos)
- Cisteína proteasa(96 productos)
- DPP-4(20 productos)
- Glutaminasa(40 productos)
- Proteasa del VIH(449 productos)
- PAI-1(25 productos)
- Inhibidores de la proteasa(50 productos)
- Receptor activado por proteasa(53 productos)
- Proteasoma(94 productos)
- Serina proteasa(50 productos)
- p97(14 productos)
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Se han encontrado 1044 productos de "Proteasas / Proteasoma"
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CP-346086 dihydrate
CAS:<p>CP-346086 dihydrate is a strong oral MTP inhibitor with 2.0 nM IC50, reducing cholesterol and triglycerides in vivo.</p>Fórmula:C26H26F3N5O3Forma y color:SolidPeso molecular:513.521APC-6860
CAS:<p>APC-6860, a serine protease inhibitor, targets multiple enzymes; most potent against human urokinase (Ki: 0.1 µM). Used in cancer research.</p>Fórmula:C9H7IN2SForma y color:SolidPeso molecular:302.13NVP-DPP728 dihydrochloride
CAS:<p>NVP-DPP728 dihydrochloride is a potent, selective DPP-IV inhibitor with a Ki of 11 nM, useful in diabetes research.</p>Fórmula:C15H20Cl2N6OForma y color:SolidPeso molecular:371.27PSI-353661
CAS:<p>PSI-353661 (GS-558093), inhibits HCV's NS5B polymerase; EC90: 8nM (wild-type), 11nM (S282T); active in human hepatocytes.</p>Fórmula:C24H32FN6O8PForma y color:SolidPeso molecular:582.525-epi-Arvestonate A
CAS:<p>5-epi-Arvestonate A, a sesquiterpenoid from Seriphidium transiliense, stimulates melanogenesis and suppresses IFN-γ-chemokine in HaCaT cells.</p>Fórmula:C16H26O5Forma y color:SolidPeso molecular:298.37Imitrodast
CAS:<p>Imitrodast is a small molecule thromboxane A2 synthase (TXA2 synthase) inhibitor for the treatment of immune system disorders, respiratory disorders, and</p>Fórmula:C13H12N2O2SPureza:98.39%Forma y color:SolidPeso molecular:260.31AP-C2
CAS:<p>AP-C2 is a potent small molecule guanosine 3',5'-cyclic monophosphate (cGMP)-dependent protein kinase II (cGKII) inhibitor with a pIC50 of 5.2 for cGKII.</p>Fórmula:C18H16N4SPureza:99.87%Forma y color:SoildPeso molecular:320.41VD2173
CAS:<p>VD2173: a macrocyclic peptide that inhibits HGF serine proteases, matriptase, and hepsin, potentially for lung cancer research.</p>Fórmula:C31H45N9O6SForma y color:SolidPeso molecular:671.81PS 915
CAS:<p>PS 915 is a substrate for colorimetric assay. It was used for plasma antithrombin.</p>Fórmula:C27H36ClN7O6Pureza:98%Forma y color:SolidPeso molecular:590.08CRA-2059 hydrochloride
<p>CRA-2059 hydrochloride is a highly specific and selective tryptase inhibitor, with a Ki of 620 pM for recombinant human tryptase-β (rHTβ)[1][2].</p>Forma y color:SolidSofosbuvir impurity A
CAS:<p>Sofosbuvir impurity A is an diastereoisomer of Sofosbuvir. Sofosbuvir is anHCV RNA replication inhibitor ,with potent anti-hepatitis C virus activity.</p>Fórmula:C22H29FN3O9PPureza:98%Forma y color:SolidPeso molecular:529.45TAPI1 acetate
<p>TAPI1 acetate (TNF-α processing inhibitor-1) is a TACE (ADAM17) inhibitor that inhibits shedding of TNF-α cytokine receptors; MMP inhibitor .</p>Fórmula:C28H41N5O7Pureza:98.82% - 99.94%Forma y color:SolidPeso molecular:559.656,6′-Dihydroxythiobinupharidine
CAS:<p>6,6′-Dihydroxythiobinupharidine, a cysteine proteases inhibitor, amplifies DNA cleavage facilitated by human topoisomerase IIα and IIβ by approximately 8-fold</p>Fórmula:C30H42N2O4SForma y color:SolidPeso molecular:526.73PROTAC 20S proteasome subunit β5 degrader 2
<p>PROTAC 20S proteasome subunit β5 degrader 2 is a PROTAC degrader targeting the 20S proteasome subunit β5 (20Sproteasomesubunit β5), with a DC50 of 0.16 μM. It inhibits the proliferation of FaDu cancer cells, showcasing an IC50 of 0.23 μM. Additionally, PROTAC20Sproteasomesubunit β5 degrader 2 demonstrates antitumor activity in a mouse model.</p>Forma y color:Odour SolidNeutrophil elastase inhibitor 4
<p>Neutrophil elastase inhibitor 4 (compound 4f) is a competitive inhibitor of human neutrophil elastase (HNE) with IC50 of 42.30 nM and Ki of 8.04 nM.</p>Fórmula:C20H21N3O5Forma y color:SolidPeso molecular:383.4Ellipyrone B
<p>Ellipyrone B, a γ-pyrone-based macrocyclic polyketide with antihyperglycemic properties, demonstrates inhibitory activity against dipeptidyl peptidase-4 (IC 50</p>Fórmula:C25H38O7Forma y color:SolidPeso molecular:450.57Tyrosinase-IN-36
<p>Tyrosinase-IN-36 is a moderately potent inhibitor of tyrosine, exhibiting an inhibition percentage of 42.75% compared to kojic acid at a concentration of 100 μM and possesses antioxidant activity.</p>Forma y color:Odour SolidSofosbuvir impurity J
CAS:<p>Sofosbuvir impurity J is an diastereoisomer of Sofosbuvir.Sofosbuvir is an HCV RNA replication inhibitor, with potent anti-hepatitis C virus activity.</p>Fórmula:C22H30FN4O8PPureza:98%Forma y color:SolidPeso molecular:528.47Tyrosinase-IN-38
<p>Tyrosinase-IN-38 (compound 6b) is a competitive inhibitor of tyrosinase, demonstrating an IC50 of 25.82 μM and exhibits antioxidant activity.</p>Forma y color:Odour SolidGrazoprevir potassium salt
CAS:<p>Grazoprevir, a drug for hepatitis C, is a second-gen NS3/4a protease inhibitor.</p>Fórmula:C38H49KN6O9SForma y color:SolidPeso molecular:805
