Proteasas / Proteasoma

Los inhibidores de proteasas y proteasomas son compuestos que bloquean la actividad de las proteasas y del proteasoma, que están involucrados en la degradación y renovación de proteínas. Estos inhibidores son vitales para estudiar la regulación de la homeostasis proteica, el control del ciclo celular y la apoptosis. Los inhibidores de proteasas y proteasomas también se utilizan en el tratamiento de enfermedades como el cáncer, donde la degradación anormal de proteínas desempeña un papel en la progresión de la enfermedad. Al inhibir las proteasas o el proteasoma, estos compuestos pueden inducir la muerte celular en células cancerosas y son herramientas esenciales tanto en la investigación básica como en el desarrollo terapéutico. En CymitQuimica, ofrecemos una amplia gama de inhibidores de proteasas y proteasomas de alta calidad para apoyar su investigación en bioquímica, biología celular y desarrollo de fármacos.

Subcategorías de "Proteasas / Proteasoma"

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Se han encontrado 1044 productos de "Proteasas / Proteasoma"

Pureza (%)

100

productos por página.

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MMP-3 Inhibitor
CAS:
- 158841-76-0
MMP-3 Inhibitor is a peptide matrix metalloproteinase-3 (MMP-3) inhibitor with a Ki value of 95 nM.MMP-3 inhibitor has anticancer and antitumor activity.
Fórmula:C₂₇H₄₆N₁₀O₉S
Pureza:98.87%
Forma y color:Solid
Peso molecular:686.78
Ref: TM-T37048
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15,16-Dihydrotanshindiol C
15,16-Dihydrotanshindiol C is a useful organic compound for research related to life sciences and the catalog number is T123985.
Fórmula:C₁₈H₁₈O₅
Forma y color:Solid
Peso molecular:314.337
Ref: TM-T123985
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Linagliptin Methyldimer
CAS:
- 1418133-47-7
Linagliptin Methyldimer is a potent dipeptidyl peptidase IV inhibitor, IC50=6 pM.
Fórmula:C₅₀H₅₆N₁₆O₄
Pureza:97.23%
Forma y color:Solid
Peso molecular:945.08
Ref: TM-T67852
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Grazoprevir potassium salt
CAS:
- 1206524-86-8
Grazoprevir, a drug for hepatitis C, is a second-gen NS3/4a protease inhibitor.
Fórmula:C₃₈H₄₉KN₆O₉S
Forma y color:Solid
Peso molecular:805
Ref: TM-T19948
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Acetyl-Calpastatin(184-210)(human)
CAS:
- 123714-50-1
Calpain inhibitor, Ki 0.2 nM for calpain I/II, doesn't affect papain/trypsin/cat L. Raises Aβ42, Aβ40 secretion & Aβ42/Aβ40 ratio.
Fórmula:C₁₄₂H₂₃₀N₃₆O₄₄S
Pureza:98%
Forma y color:Solid
Peso molecular:3177.65
Ref: TM-TP2056
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Enzyme-IN-1
CAS:
- 868540-02-7
Enzyme-IN-1（compound 1）为基于肽的N端亲核试剂（Ntn）水解酶抑制剂，特别针对20S蛋白酶体的糜胰蛋白酶样活性（CT-L）进行抑制，可能展现出抗炎特性。
Fórmula:C₃₆H₅₀N₄O₇
Forma y color:Solid
Peso molecular:650.8
Ref: TM-T74878
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Nostosin G
Nostosin G, a linear peptide with Hpla, Hty, and argininal, inhibits trypsin effectively (IC50 = 0.1 μM).
Fórmula:C₂₅H₃₃N₅O₆
Forma y color:Solid
Peso molecular:499.56
Ref: TM-T75647
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Rivulariapeptolides 1121
Rivulariapeptolides 1121 inhibits serine proteases: chymotrypsin (IC50=35.52 nM), elastase (13.24 nM), proteinase K (48.05 nM).
Fórmula:C₅₆H₈₃N₉O₁₅
Forma y color:Solid
Peso molecular:1122.31
Ref: TM-T75650
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Cepeginterferon alfa-2b
CAS:
- 1192706-52-7
Cepeginterferon alfa-2b: pegylated interferon with 20 kDa PEG for HCV, PV, ET research.
Forma y color:Liquid
Ref: TM-T76943
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Ac-DEMEEC-OH
CAS:
- 208921-05-5
Ac-DEMEEC-OH is a competitive inhibitor of the HCV NS3 protease with a Ki of 0.6 µM.
Fórmula:C₂₉H₄₄N₆O₁₆S₂
Forma y color:Solid
Peso molecular:796.82
Ref: TM-TP2848
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L 659286
CAS:
- 119742-06-2
L 659286 is one kind of cephalosporin derivative.
Fórmula:C₁₇H₂₁N₅O₇S₂
Forma y color:Solid
Peso molecular:471.51
Ref: TM-T32460
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Tyrosinase-IN-32
Tyrosinase-IN-32 (compound 11), a hydroxamate-based alkaloid extracted from black pepper (Piper nigrum L.), functions as an inhibitor of mushroom tyrosinase. In addition to its inhibitory properties, it exhibits antioxidant activity.
Fórmula:C₁₅H₁₉NO₃
Forma y color:Solid
Peso molecular:261.32
Ref: TM-TN8160
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6-Acetylnimbandiol
CAS:
- 1281766-66-2
6-Acetylnimbandiol, a non-toxic agent, inhibits tyrosinase (IC50=69.85 μM), melanin, and MITF; useful in melanoma studies.
Fórmula:C₂₈H₃₄O₈
Forma y color:Solid
Peso molecular:498.56
Ref: TM-T75506
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Rivulariapeptolides 1155
Rivulariapeptolides 1155 inhibits chymotrypsin (41.84 nM), elastase (4.94 nM), and proteinase K (56.54 nM).
Fórmula:C₅₉H₈₁N₉O₁₅
Forma y color:Solid
Peso molecular:1156.33
Ref: TM-T75648
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Nitidanin
Nitidanin is a useful organic compound for research related to life sciences and the catalog number is T125599.
Fórmula:C₂₁H₂₄O₈
Forma y color:Solid
Peso molecular:404.415
Ref: TM-T125599
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α 1(I) Collagen (614-639), human
CAS:
- 210905-12-7
This is a peptide inhibitor of collagen fibrillar matrix assembly.
Fórmula:C₁₃₄H₁₈₉N₃₇O₃₉
Pureza:98%
Forma y color:Solid
Peso molecular:2942.16
Ref: TM-TP1643
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RJS308
RJS308 is a PROTAC degrader of cyclosporin A (cyclosporin A) with a DC50 of 284 nM. It exhibits antiviral activity by inhibiting the replication of HIV-1 and HCV. (Pink: ligand for target protein CypA ligand-2; Black: linker; Blue: ligand for E3 ligase VHL (S,R,S)-AHPC-Me)
Fórmula:C₆₃H₇₅N₁₃O₁₁S
Forma y color:Solid
Peso molecular:1222.42
Ref: TM-T205591
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Pseudostellarin G
CAS:
- 156525-71-2
Pseudostellarin G, a naturally occurring cyclo-octapeptide, exhibits inhibitory activity against tyrosinase and suppresses melanin production.
Fórmula:C₄₂H₅₆N₈O₉
Forma y color:Solid
Peso molecular:816.94
Ref: TM-TP2861
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NVP-DPP728 dihydrochloride
CAS:
- 207556-62-5
NVP-DPP728 dihydrochloride is a potent, selective DPP-IV inhibitor with a Ki of 11 nM, useful in diabetes research.
Fórmula:C₁₅H₂₀Cl₂N₆O
Forma y color:Solid
Peso molecular:371.27
Ref: TM-T39481
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Leptosphaerodione
CAS:
- 138039-33-5
Leptosphaerodione from Remotididymella sp.: a potent UPS inhibitor with 3.2 μM IC50 in HeLa cells; anti-tumor.
Fórmula:C₂₁H₂₂O₅
Forma y color:Solid
Peso molecular:354.4
Ref: TM-T75488