Proteasas / Proteasoma
Los inhibidores de proteasas y proteasomas son compuestos que bloquean la actividad de las proteasas y del proteasoma, que están involucrados en la degradación y renovación de proteínas. Estos inhibidores son vitales para estudiar la regulación de la homeostasis proteica, el control del ciclo celular y la apoptosis. Los inhibidores de proteasas y proteasomas también se utilizan en el tratamiento de enfermedades como el cáncer, donde la degradación anormal de proteínas desempeña un papel en la progresión de la enfermedad. Al inhibir las proteasas o el proteasoma, estos compuestos pueden inducir la muerte celular en células cancerosas y son herramientas esenciales tanto en la investigación básica como en el desarrollo terapéutico. En CymitQuimica, ofrecemos una amplia gama de inhibidores de proteasas y proteasomas de alta calidad para apoyar su investigación en bioquímica, biología celular y desarrollo de fármacos.
Subcategorías de "Proteasas / Proteasoma"
- Acetil-CoA Carboxilasa(35 productos)
- Cisteína proteasa(96 productos)
- DPP-4(20 productos)
- Glutaminasa(40 productos)
- Proteasa del VIH(450 productos)
- PAI-1(25 productos)
- Inhibidores de la proteasa(50 productos)
- Receptor activado por proteasa(53 productos)
- Proteasoma(94 productos)
- Serina proteasa(50 productos)
- p97(14 productos)
Mostrar 3 subcategorías más
Se han encontrado 1044 productos de "Proteasas / Proteasoma"
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Voxilaprevir
CAS:<p>Voxilaprevir is an inhibitor of hepatitis C virus (HCV) nonstructural (NS) protein 3/4A protease.</p>Fórmula:C40H52F4N6O9SPureza:99.83% - 99.93%Forma y color:SolidPeso molecular:868.93Raltegravir potassium
CAS:<p>Raltegravir potassium (MK 0518 potassium salt) salt(MK0518 potassium salt) is a potent integrase (IN) inhibitor, used to treat HIV infection.</p>Fórmula:C20H20FN6O5·KPureza:98% - 99.55%Forma y color:Off-White SolidPeso molecular:482.51L-006235
CAS:L-006235 is a potent and reversible inhibitor of cathepsin K with IC50 of 0.25 nM.Fórmula:C24H30N6O2SPureza:99.37%Forma y color:SolidPeso molecular:466.6LY 3000328
CAS:<p>LY 3000328 (Cathepsin S inhibitor) is a selective inhibitor of cathepsin S.Cost-effective and quality-assured.</p>Fórmula:C25H29FN4O5Pureza:97.83% - 99.54%Forma y color:SolidPeso molecular:484.52Bemnifosbuvir
CAS:<p>Bemnifosbuvir (AT-511) is a novel phosphoramidate prodrug of 2'-fluoro-2'-C-methylguanosine-5'-monophosphate that has potent in vitro activity against HCV.</p>Fórmula:C24H33FN7O7PPureza:99.35% - 99.54%Forma y color:SolidPeso molecular:581.53Ac-DEVD-AMC
CAS:<p>Ac-DEVD-AMC (AC-ASP-MET-GLN-ASP-7-AMINO-4-METHYLCOUMARIN) is the substrate of Caspase-3 .</p>Fórmula:C30H37N5O13Pureza:98.20%Forma y color:White PowderPeso molecular:675.64Temsavir
CAS:<p>Temsavir (BMS626529) is a novel attachment inhibitor that targets HIV-1 gp120 and prevents its binding to CD4+ T cells.</p>Fórmula:C24H23N7O4Pureza:99.14%Forma y color:SolidPeso molecular:473.48Ledipasvir hydrochloride
CAS:<p>Ledipasvir hydrochloride, a hepatitis C NS5A inhibitor, has EC50 of 34 pM (1a) and 4 pM (1b), also inhibits SARS-CoV 3CL pro (IC50 1.62 µM).</p>Fórmula:C49H55ClF2N8O6Forma y color:SolidPeso molecular:925.46Letermovir
CAS:<p>Letermovir (AIC246) (AIC246) is a novel anti-CMV compound (EC50: about 5 nM in fibroblast cells). It targets the pUL56 subunit of the viral terminase complex.</p>Fórmula:C29H28F4N4O4Pureza:99.85% - 99.87%Forma y color:SolidPeso molecular:572.55UAMC00039 dihydrochloride
CAS:UAMC00039 dihydrochloride is a potent, reversible and competitive dipeptidyl peptidase II inhibitor with an IC50 of 0.48 nM.Fórmula:C16H26Cl3N3OPureza:>99.99%Forma y color:SolidPeso molecular:382.76Peptide T acetate(106362-32-7 free base)
<p>Peptide T acetate is an octapeptide from the V2 region of HIV-1 gp120.</p>Fórmula:C37H59N9O18Pureza:99.47%Forma y color:SolidPeso molecular:917.91GSK-A1
CAS:<p>GSK-A1 is a specific inhibitor of PI4KA, also inhibited calcium-driven PRL secretion without affecting calcium signaling and Prl expression.</p>Fórmula:C29H27FN6O4SPureza:98.03% - 98.97%Forma y color:SolidPeso molecular:574.63CA-074 methyl ester
CAS:<p>CA-074 methyl ester (Cathepsin B Inhibitor IV) is a selective inhibitor of Cathepsin B (IC50=36.3 nM). neuroprotective effect. High-Quality, Low-Cost!</p>Fórmula:C19H31N3O6Pureza:97.26% - 99.58%Forma y color:SolidPeso molecular:397.47NM107
CAS:NM107, a ribonucleoside, inhibits HCV NS5B polymerase. It has broad antiviral properties with EC50 of 1.85 μM in wild-type cells.Fórmula:C10H15N3O5Pureza:97.85%Forma y color:White To Off-White PowderPeso molecular:257.24Daclatasvir
CAS:<p>Daclatasvir (EBP 883/BMS-790052) is a potent HCV NS5A inhibitor with EC50 9-50 pM across various genotypes. Phase 3.</p>Fórmula:C40H50N8O6Pureza:99.81%Forma y color:SolidPeso molecular:738.88T-26c
CAS:<p>T-26c is highly potent and selective matrix metalloproteinase-13 (MMP-13) inhibitor (IC50: 6.75 pM).</p>Fórmula:C24H21N3O6SPureza:>99.99%Forma y color:SolidPeso molecular:479.51Patamostat
CAS:<p>Patamostat (E-3123) inhibits trypsin, plasmin, and thrombin; may reduce acute pancreatitis progression. IC50: trypsin 39 nM, plasmin 950 nM, thrombin 1.9 μM.</p>Fórmula:C20H20N4O4SForma y color:SolidPeso molecular:412.46ML281
CAS:<p>ML281 is a potent and selective STK33 inhibitor with IC50 of 14 nM.</p>Fórmula:C22H19N3O2SPureza:99.12% - 99.87%Forma y color:SolidPeso molecular:389.47PTACH
CAS:PTACH (Cpd 51) (NCH-51) is a SAHA-based inhibitor of human HDAC. It can potently inhibit the growth of various human Y cells (EC50: 1 to 10 μM).Fórmula:C20H26N2O2S2Pureza:87.44% - 99.74%Forma y color:SolidPeso molecular:390.56E-64
CAS:<p>E-64 (Proteinase inhibitor E 64) is an irreversible and specific cysteine protease inhibitor. The IC50 of E-64 for papain is 9 nM.</p>Fórmula:C15H27N5O5Pureza:98% - 99.95%Forma y color:White SolidPeso molecular:357.41NQ301
CAS:<p>NQ301, an antithrombotic agent, inhibits collagen-challenged rabbit platelet aggregation (IC50: 10 mg/mL).</p>Fórmula:C18H12ClNO3Pureza:99.74% - 99.76%Forma y color:SolidPeso molecular:325.75Raltegravir
CAS:<p>Raltegravir (MK-0518) is a pyrrolidinone derivative and HIV INTEGRASE INHIBITOR that is used in combination with other ANTI-HIV AGENTS for the treatment of HIV</p>Fórmula:C20H21FN6O5Pureza:99.86% - >99.99%Forma y color:SolidPeso molecular:444.422-CHLOROMETHYL-1,1-DIOXO-1,2-DIHYDRO-1λ*6*-BENZO[D]ISOTHIAZOL-3-ONE
CAS:<p>2-CHLOROMETHYL-1,1-DIOXO-1,2-DIHYDRO-1LAMBDA*6*-BENZO[D]ISOTHIAZOL-3-ONE targets the Neutrophil elastase (human).</p>Fórmula:C8H6ClNO3SPureza:97.28%Forma y color:SolidPeso molecular:231.66AF 399
CAS:<p>AF 399 is a CCR4 antagonist. It reverses the tumor-promoting environment.</p>Fórmula:C12H17N3O3SPureza:99.83%Forma y color:SolidPeso molecular:283.35LDC4297 hydrochloride
CAS:<p>LDC4297 hydrochloride is a selective and potent CDK7 inhibitor with broad-spectrum antiviral activity, useful for research on viral infections.</p>Fórmula:C23H29ClN8OForma y color:SolidPeso molecular:468.98Alvelestat
CAS:<p>Alvelestat (AZD9668) is an orally bioavailable, selective and reversible inhibitor of human neutrophil elastase (NE), with potential anti-inflammatory activity.</p>Fórmula:C25H22F3N5O4SPureza:98% - >99.99%Forma y color:SolidPeso molecular:545.53Asunaprevir
CAS:<p>Asunaprevir (BMS-650032) is an effective hepatitis C virus (HCV) NS3 protease inhibitor.</p>Fórmula:C35H46ClN5O9SPureza:99.34% - 99.8%Forma y color:SolidPeso molecular:748.29SU 4942
CAS:<p>SU-4942 is a modulator of tyrosine kinase signaling.</p>Fórmula:C15H10BrNOPureza:99% - 99.32%Forma y color:SolidPeso molecular:300.15Dabigatran Etexilate Mesylate
CAS:<p>Dabigatran Etexilate Mesylate (BIBR 1048MS) is the orally active prodrug of dabigatran. Dabigatran is a reversible and selective, direct thrombin inhibitor.</p>Fórmula:C34H41N7O5·CH4O3SPureza:99.91%Forma y color:SolidPeso molecular:723.84Tris(4-aminophenyl)methane
CAS:<p>Tris(4-aminophenyl)methane (Leucopararosaniline), a triphenylmethane dye, is a weak HCV helicase inhibitor.</p>Fórmula:C19H19N3Pureza:95.73%Forma y color:Beige Solid CrystallinePeso molecular:289.37CH 5450
CAS:<p>CH 5450 (Z-Ile-Glu-Pro-Phe-Ome) (Z-Ile-Glu-Pro-Phe-Ome) is a short peptide inhibitor of chymase in the human heart</p>Fórmula:C34H44N4O9Pureza:95.93%Forma y color:SolidPeso molecular:652.73KKI-5 acetate(97145-43-2 free base)
<p>KKI-5 acetate: Serine protease inhibitor, targets kallikrein/plasmin, potential anticancer and angioedema therapy.</p>Fórmula:C37H59N11O11Pureza:99.44%Forma y color:SolidPeso molecular:833.95Obefazimod
CAS:<p>Obefazimod (ABX-464) is a potent anti-HIV agent. ABX464 inhibits HIV-1 replication in stimulated peripheral blood mononuclear cells (PBMCs).</p>Fórmula:C16H10ClF3N2OPureza:99.86%Forma y color:SolidPeso molecular:338.71Boc-Asp(OMe)-fluoromethyl ketone
CAS:<p>Boc-Asp(OMe)-FMK is a broad-spectrum caspase inhibitor that blocks Fas-mediated processes without affecting IL-8 chemotaxis.</p>Fórmula:C11H18FNO5Pureza:≥98%Forma y color:SolidPeso molecular:263.26Cilastatin
CAS:<p>Cilastatin (MK0791): protects imipenem from renal breakdown; inhibits leukotriene D4 metabolism.</p>Fórmula:C16H26N2O5SPureza:97.76% - 99.71%Forma y color:SolidPeso molecular:358.45Velpatasvir
CAS:<p>Velpatasvir (GS-5816), also known as GS-5816, is a potent and selective Hepatitis C virus NS5A inhibitor.</p>Fórmula:C49H54N8O8Pureza:99.17% - 99.83%Forma y color:SolidPeso molecular:883Fostemsavir
CAS:<p>Fostemsavir (BMS-663068) is an HIV-1 attachment inhibitor in development for the treatment of HIV-1 infection.</p>Fórmula:C25H26N7O8PPureza:98.95%Forma y color:SolidPeso molecular:583.49S 3304
CAS:<p>S 3304 is a novel matrix metalloproteinases inhibitor which is specific for MMP-2 and MMP-9.</p>Fórmula:C24H20N2O4S2Pureza:98.09%Forma y color:SolidPeso molecular:464.56Avatrombopag
CAS:<p>Avatrombopag (YM477) is a new oral thrombopoietin (TPO) receptor agonist, activating TPO receptor and increasing megakaryocytic proliferation/differentiation</p>Fórmula:C29H34Cl2N6O3S2Pureza:99.01% - 99.63%Forma y color:SolidPeso molecular:649.65Paritaprevir
CAS:<p>Paritaprevir (ABT450) 是一种非结构蛋白 3/4A 蛋白酶抑制剂，对 HCV 1a 和 HCV 1b 的 EC50 值分别为 1 和 0.21 nM。它也是SARS-CoV 3CLpro 的抑制剂，IC50为 1.31 μM。</p>Fórmula:C40H43N7O7SPureza:99.72%Forma y color:SolidPeso molecular:765.88Samatasvir
CAS:<p>Samatasvir (ATOLIHZIXHZSBA-BTSKBWHGSA-N) is a pan-genotypic inhibitor of the HCV non-structural protein 5A.</p>Fórmula:C47H48N8O6S2Pureza:98.03%Forma y color:SolidPeso molecular:885.06Ombitasvir
CAS:<p>Ombitasvir (ABT-267) inhibits HCV protein NS5A, effective orally, EC50: 0.82-19.3 pM (genotypes 1-5), 366 pM (genotype 6a).</p>Fórmula:C50H67N7O8Pureza:97.27% - 99.56%Forma y color:SolidPeso molecular:894.11Bortezomib-pinanediol
CAS:Bortezomib-pinanediol is a proteasome inhibitor. is a prodrug of Bortezomib.Fórmula:C29H39BN4O4Pureza:97.5%Forma y color:Yellow SolidPeso molecular:518.46HIV-1 Nef-IN-1
CAS:<p>HIV-1 Nef-IN-1 is an inhibitor of HIV-1 Nef protein. It efficiently competes for Nef-SH3Hck interactions(Kd : 6.7 μM).</p>Fórmula:C18H16O2Pureza:99.90%Forma y color:SolidPeso molecular:264.322-(2-bromophenyl)-5-chloro-4H-3,1-benzoxazin-4-one
CAS:<p>2-(2-bromophenyl)-5-chloro-4H-3,1-benzoxazin-4-one is an human neutrophil elastase inhibitor.</p>Fórmula:C14H7BrClNO2Pureza:97.36%Forma y color:SolidPeso molecular:336.57Proteasome inhibitor IX
CAS:<p>Proteasome inhibitor IX (PS-IX) is an inhibitor of chymotrypsin-like activity of the 20S proteasome (IC50 ~1 μM).</p>Fórmula:C20H21B2NO5Pureza:99.77%Forma y color:SolidPeso molecular:377.01Grazoprevir hydrate
CAS:<p>Grazoprevir: Hepatitis C protease inhibitor effective against various genotypes, including drug-resistant strains.</p>Fórmula:C38H52N6O10SPureza:98%Forma y color:SolidPeso molecular:784.92P-113 acetate
<p>P-113 acetate: AMP from histatin 5, treats gingivitis and HIV-related oral candidiasis safely and effectively.</p>Fórmula:C73H114N28O15Pureza:97.4%Forma y color:SolidPeso molecular:1623.86Anagliptin
CAS:<p>Anagliptin (SK-0403) is a potent Inhibitor of DPP-4(IC50 of 3.8 nM), for the treatment of type 2 diabetes mellitus.</p>Fórmula:C19H25N7O2Pureza:97.59% - 99.98%Forma y color:SolidPeso molecular:383.45L-Albizziin
CAS:<p>L-Albizziin (L-beta-Ureidoalanine) is a glutamase inhibitor and is a glutaminyl-tRNA synthetase inhibitor.</p>Fórmula:C4H9N3O3Pureza:99.98%Forma y color:White PowderPeso molecular:147.13
![2-CHLOROMETHYL-1,1-DIOXO-1,2-DIHYDRO-1λ*6*-BENZO[D]ISOTHIAZOL-3-ONE](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FT8602.webp&w=3840&q=75)
