Proteasas / Proteasoma
Los inhibidores de proteasas y proteasomas son compuestos que bloquean la actividad de las proteasas y del proteasoma, que están involucrados en la degradación y renovación de proteínas. Estos inhibidores son vitales para estudiar la regulación de la homeostasis proteica, el control del ciclo celular y la apoptosis. Los inhibidores de proteasas y proteasomas también se utilizan en el tratamiento de enfermedades como el cáncer, donde la degradación anormal de proteínas desempeña un papel en la progresión de la enfermedad. Al inhibir las proteasas o el proteasoma, estos compuestos pueden inducir la muerte celular en células cancerosas y son herramientas esenciales tanto en la investigación básica como en el desarrollo terapéutico. En CymitQuimica, ofrecemos una amplia gama de inhibidores de proteasas y proteasomas de alta calidad para apoyar su investigación en bioquímica, biología celular y desarrollo de fármacos.
Subcategorías de "Proteasas / Proteasoma"
- Acetil-CoA Carboxilasa(35 productos)
- Cisteína proteasa(96 productos)
- DPP-4(20 productos)
- Glutaminasa(40 productos)
- Proteasa del VIH(451 productos)
- PAI-1(25 productos)
- Inhibidores de la proteasa(50 productos)
- Receptor activado por proteasa(53 productos)
- Proteasoma(94 productos)
- Serina proteasa(49 productos)
- p97(14 productos)
Mostrar 3 subcategorías más
Se han encontrado 1039 productos de "Proteasas / Proteasoma"
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Azo-Resveratrol
CAS:<p>Azo-Resveratrol is an analog of Resveratrol used as a potent tyrosinase inhibitor.</p>Fórmula:C12H10N2O3Forma y color:SolidPeso molecular:230.22Sortin1
CAS:Sortin1, a chemical genetic-hit compound, specifically induces mislocalization of both soluble and membrane-associated vacuolar markers in plants and yeast.Fórmula:C26H19NO6Pureza:98%Forma y color:SolidPeso molecular:441.43MDK7677
CAS:<p>MDK7677 is a selective inhibitor of cathepsin B endopeptidase and exopeptidase activities.</p>Fórmula:C12H10N4O3Forma y color:SolidPeso molecular:258.23Furaprofen
CAS:<p>Furaprofen is an HCV inhibitor with anti-inflammatory activity that inhibits carrageenan-induced paw edema in rats.</p>Fórmula:C17H14O3Pureza:98.49% - 99.52%Forma y color:SolidPeso molecular:266.29(3S,4S)-A2-32-01
<p>(3S,4S)-A2-32-01, a less active (S,S)-enantiomer of A2-32-01. A2-32-01 is a potent caseinolytic protein proteases (ClpP) inhibitor .</p>Fórmula:C19H27NO2Forma y color:SolidPeso molecular:301.42GEMSA
CAS:<p>GEMSA is a potent inhibitor of enkephalin convertase ( K i =8.8 nM) with analgesic effect[1].</p>Fórmula:C7H13N3O4SForma y color:SolidPeso molecular:235.26MMP-1-IN-1
<p>MMP-1-IN-1 is a highly potent MMP-1 inhibitor with an IC 50 of 0.034 μM .</p>Fórmula:C14H17ClN2O3Forma y color:SolidPeso molecular:296.75Gemigliptin Tartrate(911637-19-9 free base)
CAS:<p>Gemigliptin Tartrate (LC15-0444 tartrate) is a highly selective, reversible and competitive inhibitor of dipeptidyl peptidase-4 (DPP-4).</p>Fórmula:C22H25F8N5O8Pureza:>99.99%Forma y color:SolidPeso molecular:639.45AK 275
CAS:<p>AK 275 is a calpain inhibitor that prevents degradation of cytoskeletal and myelin proteins in spinal cord in vitro.</p>Fórmula:C20H31N3O4Forma y color:SolidPeso molecular:377.48AZD-9684
CAS:<p>AZD-9684, a carboxypeptidase U inhibitor, is used potentially for the prevention of thrombosis.</p>Fórmula:C10H14N2O2SForma y color:SolidPeso molecular:226.3SAP2-IN-1
CAS:<p>SAP2-IN-1 inhibits secreted aspartate protease 2 (IC50: 0.92 μM), doesn't work in vitro, and helps research infections.</p>Fórmula:C34H29NO7Forma y color:SolidPeso molecular:563.6ITX-4520
CAS:<p>ITX-4520 novel highly potent, orally bioavailable inhibitor of hepatitis C virus (HCV) entry.</p>Fórmula:C24H23F2N3OSForma y color:SolidPeso molecular:439.52NAAA-IN-2
CAS:<p>NAAA-IN-2, a selective inhibitor with 50 nM IC50, targets NAAA, an enzyme hydrolyzing PEA/OEA, and may aid inflammation and pain studies.</p>Fórmula:C11H13N3O2SForma y color:SolidPeso molecular:251.3L 722151
CAS:<p>L 722151 is an FXIIIa inhibitor.</p>Fórmula:C8H9ClN2O5S3Pureza:98%Forma y color:SolidPeso molecular:344.82TAPI-0
CAS:<p>TAPI-0 is a matrix metalloprotease (MMP) and TACE inhibitor.</p>Fórmula:C24H32N4O5Forma y color:SolidPeso molecular:456.53Chymase-IN-1
CAS:<p>Chymase-IN-1 is a selective, orally active inhibitor of human mast cell chymase (IC50: 29 nM).</p>Fórmula:C20H15ClNO4PSPureza:99.17%Forma y color:SolidPeso molecular:431.83Tyrosinase-IN-10
CAS:<p>Tyrosinase-IN-10 serves as a partially competitive inhibitor of tyrosinase, demonstrating an inhibition concentration (IC50) value of 1.6 μM against the enzyme'</p>Fórmula:C16H12O4Forma y color:SolidPeso molecular:268.26ADAMTS-5-IN-2
CAS:<p>ADAMTS-5-IN-2 is a potent inhibitor of ADAMTS-5, exhibiting an IC50 of 0.71 µM, and holds potential for osteoarthritis research.</p>Fórmula:C17H15N3OSForma y color:SolidPeso molecular:309.39Calpain-2-IN-1
CAS:<p>Calpain-2-IN-1 is a selective calpain-2 inhibitor that prolongs ERK activation and thus enhances learning and memory.</p>Fórmula:C28H37N3O7Forma y color:SolidPeso molecular:527.61Safironil
CAS:<p>Safironil, a novel antifibrotic, competitively inhibits collagen synthesis and modulates fibrosis, impacting type I/III collagen levels.</p>Fórmula:C15H23N3O4Pureza:99.83%Forma y color:SolidPeso molecular:309.36BR351
CAS:<p>BR351 is a brain penetrant MMP inhibitor (IC50s: 4, 2, 11, 50 nM for MMP2, MMP8, MMP9 and MMP13).</p>Fórmula:C20H25FN2O5SPureza:98%Forma y color:SolidPeso molecular:424.49HCV-IN-35
CAS:<p>HCV-IN-35 is a potent inhibitor of HCV and shows potential for infectious disease research.</p>Fórmula:C30H36ClN5Forma y color:SolidPeso molecular:502.09Calpain Inhibitor XI
CAS:<p>Calpain Inhibitor XI, a reversible covalent inhibitor of calpain-1, is utilized in the research of neurodegenerative disorders.</p>Fórmula:C26H40N4O6Forma y color:SolidPeso molecular:504.62AM 4299 B
CAS:<p>AM 4299 B is a novel inhibitor of a thiol protease.</p>Fórmula:C16H27N3O7Pureza:98%Forma y color:SolidPeso molecular:373.4MDL 27399
CAS:<p>MDL 27399 suppresses human neutrophil cathepsin G.</p>Fórmula:C26H36N4O8Forma y color:SolidPeso molecular:532.59CAA0225
CAS:<p>CAA0225 is a selective inhibitor of cathepsin L. CAA0225 is a probe for autophagic proteolysis.</p>Fórmula:C28H29N3O5Forma y color:SolidPeso molecular:487.55Immunoproteasome inhibitor 1
CAS:<p>Potent, reversible immunoproteasome inhibitor; Ki: β5c 1.18 μM, β1i 0.27 μM, β5i 1.91 μM; potential in treating cancer.</p>Fórmula:C20H26N2O4Forma y color:SolidPeso molecular:358.43α-Glucosidase-IN-5
CAS:<p>α-Glucosidase-IN-5 (compound 8) is isolated from a twig extract of Polyalthia cinnamomea which is a potent α-glucosidase inhibitor with an IC50 of 57.9 µM.</p>Fórmula:C15H13NO3Forma y color:SolidPeso molecular:255.27JO146
CAS:<p>JO146为针对沙眼衣原体高温需要蛋白A(CtHtrA)的蛋白酶抑制剂，其对CtHtrA和人中性粒细胞弹性蛋白酶(HNE)的IC50值分别为21.86 μM和1.15 μM，可应用于细菌感染的抑制。</p>Fórmula:C31H44N3O7PForma y color:SolidPeso molecular:601.67L-873724
CAS:<p>L-873724: Selective, reversible cathepsin K inhibitor; IC50s—cat K: 0.2 nM, cat S: 178 nM, cat L: 264 nM, cat B: 5239 nM; inhibits bone resorption.</p>Fórmula:C23H26F3N3O3SPureza:98%Forma y color:SolidPeso molecular:481.53(R)-ND-336
CAS:<p>(R)-ND-336: potent, selective MMP-9 inhibitor (K i = 19 nM); inhibits MMP-2 (127 nM), MMP-14 (119 nM); studied for diabetic foot ulcers.</p>Fórmula:C16H18ClNO3S2Forma y color:SolidPeso molecular:371.89Adafosbuvir PM
CAS:<p>Adafosbuvir PM (AL-335 PM) is a small molecule NS5B inhibitor that can be used to study chronic hepatitis C.</p>Fórmula:C10H13FN2O6Pureza:97.08%Forma y color:SolidPeso molecular:276.22OM-189
CAS:<p>OM-189 is a selective inhibitor of synthetic thrombin.</p>Fórmula:C24H36N6O3SPureza:98%Forma y color:SolidPeso molecular:488.65MMP-2/9-IN-1
CAS:<p>MMP-2/9-IN-1 (Compound 4a) is a potent dual inhibitor of MMP-2 (IC50: 56 nM) and MMP-9 (IC50: 38 nM). leading to DNA fragmentation.</p>Fórmula:C14H16IN7SForma y color:SolidPeso molecular:441.29GLS1 Inhibitor-3
CAS:<p>GLS1 Inhibitor-3 (compound C147) is a potent inhibitor of GLS1 (IC50: 27.98 nM) and exhibits anti-proliferative effects.</p>Fórmula:C30H32N10O2SForma y color:SolidPeso molecular:596.71CA 074
CAS:<p>CA 074 is a potent inhibitor of cathepsin B with a Ki value of 2 to 5 nM.CA 074 inhibits ischemic hippocampal neuronal death in primates and attenuates</p>Fórmula:C18H29N3O6Pureza:97.80%Forma y color:SolidPeso molecular:383.44XMU-MP-2
CAS:<p>XMU-MP-2 is a potent and selective protease inhibitor with anticancer activity that inhibits the growth of oncogenic BRK-driven tumors in a mouse xenograft</p>Fórmula:C32H33F3N8O2Pureza:99.29%Forma y color:SolidPeso molecular:618.65Tyrosinase-IN-1
CAS:<p>Tyrosinase-IN-1: potent inhibitor for skin-whitening & food preservation with uses in cosmetics & medicine.</p>Fórmula:C10H9N3O2S2Forma y color:SolidPeso molecular:267.33HCV-IN-36
CAS:<p>HCV-IN-36: oral HCV inhibitor, EC50 0.016 μM, CC50 8.78 μM, potent antiviral.</p>Fórmula:C30H36ClN5Forma y color:SolidPeso molecular:502.09BMS-363131
CAS:<p>BMS-363131 (BMS363131) is a potent and selective trypsin inhibitor with an IC50 value of <1.7 nM.</p>Fórmula:C28H40N6O5Pureza:97.99%Forma y color:SolidPeso molecular:540.652',5-Difluoro-2'-deoxycytidine
CAS:<p>2',5-Difluoro-2'-deoxycytidine has potent anti-HCV activity and toxicity to rRNA.</p>Fórmula:C9H11F2N3O4Pureza:98%Forma y color:SolidPeso molecular:263.2BRD-8899
CAS:<p>BRD-8899 is a STK33 inhibitor, with an IC 50 of 11 nM [1].</p>Fórmula:C17H22N4O3SForma y color:SolidPeso molecular:362.45Tyrosinase-IN-5
CAS:<p>Tyrosinase-IN-5 (16c) inhibits tyrosinase with 0.02 μM IC50, reduces melanogenesis, and is low-toxicity.</p>Fórmula:C18H13N3O6Forma y color:SolidPeso molecular:367.31Elasnin
CAS:<p>Elasnin is a reversible inhibitor of elastase for human granulocyte and pancreatic enzymes with IC50 values of 1.3 and 30 µg/ml, respectively.</p>Fórmula:C24H40O4Forma y color:SolidPeso molecular:392.57ASPER-29
CAS:<p>ASPER-29, an Asperphenamate analog, inhibits cathepsins L/S with IC50s of 6.03/5.02 μM, useful in cancer migration/invasion research.</p>Fórmula:C31H29BrN2O5SForma y color:SolidPeso molecular:621.54Gü1303
CAS:<p>Gü1303 is a highly potent and reversible inhibitor of Cathepsin K (CatK), with a Ki value of 0.91 nM for mature CatK (mCatK).</p>Fórmula:C20H22N4O3Forma y color:SolidPeso molecular:366.41CAY10704
CAS:<p>CAY10704: Potent HCV inhibitor, EC50=17 nM, low cytotoxicity, good in mice, liver-targeted, not hepatotoxic, weak against dengue.</p>Fórmula:C18H20Cl2N2Forma y color:SolidPeso molecular:335.27DPP-4-IN-1
CAS:<p>DPP-4-IN-1 inhibits DPP-4 with 49 nM IC50, ideal for diabetes study, akin to Alogliptin.</p>Fórmula:C19H19ClN6Forma y color:SolidPeso molecular:366.85AA10 TG2 inhibitor
CAS:<p>AA10 is an irreversible inhibitor of transglutaminase 2 (TG2).</p>Fórmula:C32H36N4O5Forma y color:SolidPeso molecular:556.65ABT-770
CAS:<p>ABT-770: an orally potent and selective MMP inhibitor, shown to reduce tumor growth in animal models.</p>Fórmula:C22H22F3N3O6Forma y color:SolidPeso molecular:481.42
