Proteasas / Proteasoma
Los inhibidores de proteasas y proteasomas son compuestos que bloquean la actividad de las proteasas y del proteasoma, que están involucrados en la degradación y renovación de proteínas. Estos inhibidores son vitales para estudiar la regulación de la homeostasis proteica, el control del ciclo celular y la apoptosis. Los inhibidores de proteasas y proteasomas también se utilizan en el tratamiento de enfermedades como el cáncer, donde la degradación anormal de proteínas desempeña un papel en la progresión de la enfermedad. Al inhibir las proteasas o el proteasoma, estos compuestos pueden inducir la muerte celular en células cancerosas y son herramientas esenciales tanto en la investigación básica como en el desarrollo terapéutico. En CymitQuimica, ofrecemos una amplia gama de inhibidores de proteasas y proteasomas de alta calidad para apoyar su investigación en bioquímica, biología celular y desarrollo de fármacos.
Subcategorías de "Proteasas / Proteasoma"
- Acetil-CoA Carboxilasa(35 productos)
- Cisteína proteasa(96 productos)
- DPP-4(20 productos)
- Glutaminasa(40 productos)
- Proteasa del VIH(450 productos)
- PAI-1(25 productos)
- Inhibidores de la proteasa(50 productos)
- Receptor activado por proteasa(53 productos)
- Proteasoma(94 productos)
- Serina proteasa(50 productos)
- p97(14 productos)
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Se han encontrado 1044 productos de "Proteasas / Proteasoma"
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Cathepsin X-IN-1
CAS:<p>Cathepsin X-IN-1 (compound 25) reduces the migration of PC-3 cell with low cytotoxic that is a potent inhibitor of Cathepsin X (IC 50 = 7.13 μM) [1].</p>Fórmula:C15H13N3O3SPureza:99.34%Forma y color:SolidPeso molecular:315.35(2RS)-FPMPA
CAS:(2RS)-FPMPA（FPMPA） has antiviral activity with an IC50 value of 1.85 μM measured in human MT12 cells infected with SHIV (DH4R).Fórmula:C9H13FN5O4PPureza:99.9% - >99.99%Forma y color:SolidPeso molecular:305.2KM-023
CAS:<p>KM-023 is a new second-generation non-nucleoside reverse transcriptase inhibitor for the study of human immunodeficiency virus (HIV) type 1 infection.</p>Fórmula:C18H19N3O3Pureza:99.47% - >99.99%Forma y color:SolidPeso molecular:325.36PG-116800
CAS:<p>PG-116800 (PG-530742) is a matrix metalloproteinase (MMP) inhibitor. PG-116800 can be used in studies about the treatment of osteoarthritis.</p>Fórmula:C24H27N3O7SPureza:98.03% - 99.66%Forma y color:SolidPeso molecular:501.55Granotapide
CAS:<p>Granotapide is a microsomal triglyceride transfer protein (MTP) inhibitor that treats and rather prevents atherosclerosis, coronary artery disease, metabolic</p>Fórmula:C39H37F3N2O8Pureza:99.70% - 99.79%Forma y color:SolidPeso molecular:718.71Setrobuvir
CAS:<p>Setrobuvir (ANA-598) is an orally active non-nucleoside HCV NS5B polymerase inhibitor with inhibitory effects on de novo RNA synthesis and primer extension with</p>Fórmula:C25H25FN4O6S2Pureza:98.92% - >99.99%Forma y color:SolidPeso molecular:560.62CZL55
CAS:<p>CZL55 is a potent caspase-1 inhibitor with an IC50 value of 0.024 μM.CZL55 has low cytotoxicity and can be used in the study of febrile seizures (FS).</p>Fórmula:C20H22N2O6Pureza:98.19%Forma y color:SolidPeso molecular:386.4Uprifosbuvir
CAS:Uprifosbuvir is an inhibitor of uridine nucleotide analog HCV NS5B polymerase.Fórmula:C22H29ClN3O9PPureza:99.73% - >99.99%Forma y color:SolidPeso molecular:545.91Atevirdine
CAS:<p>Atevirdine is an HIV-1 reverse transcriptase inhibitor with antiviral activity for the study of the AIDS dementia complex (ADC).</p>Fórmula:C21H25N5O2Pureza:98.20%Forma y color:SolidPeso molecular:379.46Etarotene
CAS:<p>Etarotene (Arotinoid ethyl sulphone) is an ethylsulfonyl derivative of aloe acid with differentiation-inducing and potentially antitumor activity.Etarotene is a</p>Fórmula:C25H32O2SPureza:99.58% - 99.93%Forma y color:SolidPeso molecular:396.59TY-51469
CAS:<p>TY-51469 is an inhibitor of chymase (IC50s for simian and human chymases: 0.4 and 7.0 nM, respectively).</p>Fórmula:C20H15FN2O6S4Pureza:99.65%Forma y color:SolidPeso molecular:526.6MMP-2/MMP-9 Inhibitor I
CAS:<p>MMP-2/MMP-9-IN-1: oral IV collagenase inhibitor; IC50: 0.24 μM (MMP-9), 0.31 μM (MMP-2); targets cancer.</p>Fórmula:C21H19NO4SPureza:99.74%Forma y color:SolidPeso molecular:381.44CPA inhibitor
CAS:<p>CPA inhibitor (Carboxypeptidase inhibitor) is a potent carboxypeptidase A (CPA) inhibitor with a Ki of 0.32 μM.</p>Fórmula:C18H19NO4Pureza:99.94%Forma y color:SolidPeso molecular:313.35BAY-43-9695
CAS:<p>BAY-43-9695 is a non-nucleoside compound with anti-human cytomegalovirus (HCMV) activity. It is the major metabolite of BAY-38-4766.</p>Fórmula:C22H25N3O4SPureza:99.50% - 99.65%Forma y color:SolidPeso molecular:427.52UPGL00004
CAS:<p>UPGL00004: potent GAC inhibitor, IC50=29 nM, Kd=27 nM, suppresses triple-negative breast cancer cell growth.</p>Fórmula:C25H26N8O2S2Pureza:97.93%Forma y color:SolidPeso molecular:534.66Sovaprevir
CAS:<p>Sovaprevir is a non-structural 3 (NS3) protease inhibitor with antiviral activity for the treatment of HCV infection.</p>Fórmula:C43H53N5O8SPureza:99.11%Forma y color:SolidPeso molecular:799.97Melagatran
CAS:<p>Melagatran is an orally available, direct synthetic thrombin inhibitor that does not require endogenous cofactors other than thrombin.Cost-effective and quality-assured.</p>Fórmula:C22H31N5O4Pureza:98.29% - >99.99%Forma y color:SolidPeso molecular:429.51TG-2-IN-1
CAS:<p>TG-2-IN-1 (Compound D003) is a transglutaminase-2 ( TGM-2 ) inhibitor. TG-2-IN-1 can be used in myopia research[1].</p>Fórmula:C8H13ClN2OSPureza:98.43%Forma y color:SolidPeso molecular:220.72Opaviraline
CAS:<p>Opaviraline (GW-420867X) is a potent reverse transcriptase inhibitor that inhibits Human immunodeficiency virus 1 and has the potential to treat HIV infection.</p>Fórmula:C14H17FN2O3Pureza:99.94%Forma y color:SolidPeso molecular:280.29NP-313
CAS:<p>NP-313 (NSC-4264) is a potent antithrombotic that blocks platelet aggregation via thromboxane A2 synthesis inhibition and targets SOCC-mediated Ca2+ efflux.</p>Fórmula:C12H8ClNO3Pureza:98.97%Forma y color:SolidPeso molecular:249.65Lenacapavir
CAS:<p>Lenacapavir (GS-6207) is the first HIV-1 capsid inhibitor approved by the U.S. Food and Drug Administration, the European Medicines Agency, and Health Canada for the treatment of MDR HIV-1 infection.Cost-effective and quality-assured.</p>Fórmula:C39H32ClF10N7O5S2Pureza:99.61% - 99.87%Forma y color:SolidPeso molecular:968.28Gemigliptin
CAS:<p>Gemigliptin (LC15-0444) is a potent dipeptidyl peptidase-4 (DPP-4) inhibitor(KD : 7.25 nM.)</p>Fórmula:C18H19F8N5O2Pureza:99.72%Forma y color:SolidPeso molecular:489.36DB04760
CAS:<p>DB04760: selective MMP-13 inhibitor, non-zinc-chelating, IC50=8nM, reduces paclitaxel neurotoxicity, anticancer.</p>Fórmula:C22H20F2N4O2Pureza:99.93% - 99.99%Forma y color:SolidPeso molecular:410.42MMP2-IN-3
CAS:<p>MMP2-IN-3 is a potent inhibitor of matrix metalloproteinases (MMP-2) (IC50: 31 μM).</p>Fórmula:C23H21N3OPureza:99.38%Forma y color:SolidPeso molecular:355.43TG2-IN-3h
CAS:<p>TG2-IN-3h is a highly selective, potent, cell-permeable fluorescent irreversible tissue transglutaminase (tg2) inhibitor</p>Fórmula:C21H26N4O4SPureza:99.34% - 99.76%Forma y color:SolidPeso molecular:430.52BDCRB
<p>BDCRB disrupts HCMV DNA maturation by altering terminase cleavage, extending packaging 30 kb until second site.</p>Fórmula:C12H11BrCl2N2O4Pureza:99.41% - 99.43%Forma y color:SoildPeso molecular:398.04MK-8325
CAS:<p>MK-8325 is a potent and orally available HCV NS5A inhibitor with replicative activity against a wide range of genotypes.MK-8325 has demonstrated bioavailability</p>Fórmula:C43H54Cl2F2N8O6SiPureza:>99.99%Forma y color:SolidPeso molecular:915.93Sirpiglenastat
CAS:<p>Sirpiglenastat (DRP-104) is a glutamine antagonist, a prodrug of DON, with antitumor activity that acts by suppressing the adaptive immune system.</p>Fórmula:C22H27N5O5Pureza:98.01% - 98.37%Forma y color:SolidPeso molecular:441.4820S Proteasome activator 1
CAS:<p>20S Proteasome activator 1: IC50—0.3 μM (trypsin), 0.7 μM (chymotrypsin), 1.8 μM (caspase); reduces alpha-synuclein A53T, aids neurodegenerative studies.</p>Fórmula:C27H19ClF2N2OSPureza:99.82%Forma y color:SolidPeso molecular:492.97P32/98 hemifumarate
CAS:<p>P32/98 hemifumarate is a DPP4 inhibitor with hypoglycemic properties and is used in the study of type 2 diabetes.</p>Fórmula:C22H40N4O6S2Pureza:99.46%Forma y color:SolidPeso molecular:520.71L 756423
CAS:<p>L756423 is a potent, selective HIV protease inhibitor (Ki=0.049 nM), effective against HIV spread in MT25 lymphocytes at 0.1-0.5 nM, useful for AIDS research.</p>Fórmula:C39H48N4O5Pureza:99.34% - 99.88%Forma y color:SolidPeso molecular:652.82BMS-488043
CAS:<p>BMS-488043 is a novel and unique oral small molecule HIV fusion inhibitor that inhibits the attachment of Human Immunodeficiency Virus type 1 (HIV-1) to CD4(+)</p>Fórmula:C22H22N4O5Pureza:99.95%Forma y color:SolidPeso molecular:422.43VRK-IN-1
CAS:VRK-IN-1 is a potent and selective inhibitor of cowpox-associated kinase 1 (VRK1), which can be used in the study of neurological disorders.Fórmula:C18H11F4NO2Pureza:99.18% - 99.25%Forma y color:SolidPeso molecular:349.28MMP-145
CAS:<p>MMP-145 is used as a protease inhibitor.</p>Fórmula:C20H20N2O7SPureza:98%Forma y color:SolidPeso molecular:432.45LM-030
CAS:<p>LM-030, also known as BPR277, is a novel inhibitor of kallikrein-related peptidase 7 (KLK7) and epidermal elastase 2 (ELA2).</p>Fórmula:C46H72N8O12Forma y color:SolidPeso molecular:929.11SID 26681509
CAS:<p>SID 26681509 is a selective, reversible and competitive human cathepsin L inhibitor (IC50 of 56 nM).</p>Fórmula:C27H33N5O5SPureza:98.16%Forma y color:SolidPeso molecular:539.65HCV-IN-44
CAS:<p>HCV-IN-44 (compound 28) is an inhibitor of the HCV NS5B protein, efficacious in suppressing HCV virus replication and useful for researching HCV infection [1].</p>Fórmula:C24H26FN3O5SForma y color:SolidPeso molecular:487.54(1R,4S)-Yimitasvir diphosphate
CAS:<p>Yimitasvir diphosphate, also known as Emitasvir, is an orally-administered inhibitor of the hepatitis C virus (HCV) nonstructural protein 5A (NS5A).</p>Fórmula:C49H64N8O14P2Forma y color:SolidPeso molecular:1051.03MeOSuc-AAPV-CMK
CAS:<p>MeOSuc-AAPV-CMK (Elastase Inhibitor III) serves as an inhibitor of elastase, as well as cathepsin G and proteinase 3, and impedes leukocyte elastase-mediated</p>Fórmula:C22H35ClN4O7Forma y color:SolidPeso molecular:502.99Human enteropeptidase-IN-1
CAS:<p>Enteropeptidase-IN-1: orally active, potent inhibitor, low systemic exposure, for anti-obesity research.</p>Fórmula:C20H18N4O7Forma y color:SolidPeso molecular:426.38Ecallantide
CAS:<p>Ecallantide (DX-88) is a recombinant inhibitor specifically targeting plasma kallikrein, which serves to impede the synthesis of bradykinin.</p>Fórmula:C305H448N88O91S8Forma y color:SolidPeso molecular:7059.88Z-DEVD-CMK
CAS:<p>Z-DEVD-CMK irreversibly inhibits various cathepsins in vitro [1].</p>Fórmula:C27H35ClN4O12Forma y color:SolidPeso molecular:643.04DCLK1-IN-2
CAS:<p>DCLK1-IN-2 (Compound I-5) is a potent inhibitor of DCLK1, exhibiting an IC50 of 171.3 nM, and demonstrates significant antiproliferative effects on SW1990 cell</p>Fórmula:C26H32N8O3SForma y color:SolidPeso molecular:536.65Tyropeptin A-4
CAS:<p>Tyropeptin A-4 is used as a proteasome inhibitor.</p>Fórmula:C31H41N3O6Pureza:98%Forma y color:SolidPeso molecular:551.67BMS-189664 HCl
CAS:<p>BMS-189664 HCl is a selective and orally active thrombin active site inhibitor.</p>Fórmula:C22H35ClN6O4SPureza:98%Forma y color:SolidPeso molecular:515.07SQ 32056
CAS:<p>SQ 32056 is a cathepsin E inhibitor.</p>Fórmula:C37H56N4O5Pureza:98%Forma y color:SolidPeso molecular:636.86AZD-7295
CAS:<p>AZD-7295 (A-689) is an NS5A inhibitor that may be used to treat HCV infection.</p>Fórmula:C32H35F3N4O5SForma y color:SolidPeso molecular:644.7ND-378
CAS:<p>ND-378 is a potent and selective inhibitor of MMP-2 with no inhibition on MMP-9 and MMP-14.</p>Fórmula:C18H19NO4S2Pureza:98%Forma y color:SolidPeso molecular:377.48BAY-320
CAS:<p>BAY-320 is a Bub1 inhibitor. With an IC50 of 680 nM for human Bub1 in the presence of 2 mM ATP.</p>Fórmula:C26H26F2N6O2Pureza:98%Forma y color:SolidPeso molecular:492.52Flovagatran sodium
CAS:<p>Flovagatran sodium, a thrombin inhibitor, is used potentially for the treatment of thrombosis.</p>Fórmula:C27H36BN3NaO7Pureza:98%Forma y color:SolidPeso molecular:548.4
