Proteasas / Proteasoma
Los inhibidores de proteasas y proteasomas son compuestos que bloquean la actividad de las proteasas y del proteasoma, que están involucrados en la degradación y renovación de proteínas. Estos inhibidores son vitales para estudiar la regulación de la homeostasis proteica, el control del ciclo celular y la apoptosis. Los inhibidores de proteasas y proteasomas también se utilizan en el tratamiento de enfermedades como el cáncer, donde la degradación anormal de proteínas desempeña un papel en la progresión de la enfermedad. Al inhibir las proteasas o el proteasoma, estos compuestos pueden inducir la muerte celular en células cancerosas y son herramientas esenciales tanto en la investigación básica como en el desarrollo terapéutico. En CymitQuimica, ofrecemos una amplia gama de inhibidores de proteasas y proteasomas de alta calidad para apoyar su investigación en bioquímica, biología celular y desarrollo de fármacos.
Subcategorías de "Proteasas / Proteasoma"
- Acetil-CoA Carboxilasa(34 productos)
- Cisteína proteasa(96 productos)
- DPP-4(20 productos)
- Glutaminasa(40 productos)
- Proteasa del VIH(449 productos)
- PAI-1(25 productos)
- Inhibidores de la proteasa(50 productos)
- Receptor activado por proteasa(53 productos)
- Proteasoma(94 productos)
- Serina proteasa(50 productos)
- p97(14 productos)
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Se han encontrado 1044 productos de "Proteasas / Proteasoma"
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FFAGLDD
<p>"FFAGLDD: MMP9 peptide for controlled DOX delivery inside cells."</p>Fórmula:C37H49N7O12Pureza:98%Forma y color:SolidPeso molecular:783.82Sadopeptins B
<p>Sadopeptins B, a natural product isolated from Streptomyces sp., is a potent proteasome inhibitor [1].</p>Fórmula:C48H69N9O13SForma y color:SolidPeso molecular:1012.18Peptide 74
CAS:<p>Peptide 74 is a synthetic peptide. It also inhibits the activated form of this enzyme.</p>Fórmula:C62H107N23O20S2Pureza:98%Forma y color:SolidPeso molecular:1558.79FFAGLDD TFA
<p>FFAGLDD TFA: MMP9 peptide for controlled DOX delivery to cytoplasm.</p>Fórmula:C39H50F3N7O14Pureza:98%Forma y color:SolidPeso molecular:897.85Monodes(N-carboxymethyl)valine Daclatasvir
CAS:<p>Monodes(N-carboxymethyl)valine Daclatasvir, or Daclatasvir Impurity A, degrades Daclatasvir, a strong HCV NS5A inhibitor.</p>Fórmula:C33H39N7O3Forma y color:SolidPeso molecular:581.71Neutrophil elastase inhibitor 4
<p>Neutrophil elastase inhibitor 4 (compound 4f) is a competitive inhibitor of human neutrophil elastase (HNE) with IC50 of 42.30 nM and Ki of 8.04 nM.</p>Fórmula:C20H21N3O5Forma y color:SolidPeso molecular:383.4BAY 1217224
CAS:<p>BAY 1217224 is a neutral, non-prodrug Thrombin inhibitor with good oral pharmacokinetics.</p>Fórmula:C24H27ClFN3O5Forma y color:SolidPeso molecular:491.94Calpain Inhibitor-1
CAS:<p>Calpain Inhibitor-1, a potent Calpain 1 blocker, has IC50 of 100 nM and Ki of 2.89 μM.</p>Fórmula:C19H17FN6O5SForma y color:SolidPeso molecular:460.44TAPI1 acetate
<p>TAPI1 acetate (TNF-α processing inhibitor-1) is a TACE (ADAM17) inhibitor that inhibits shedding of TNF-α cytokine receptors; MMP inhibitor .</p>Fórmula:C28H41N5O7Pureza:98.82% - 99.94%Forma y color:SolidPeso molecular:559.65EP 171
CAS:<p>EP 171 is a potent agonist of TP-receptors.</p>Fórmula:C23H29FO5Forma y color:SolidPeso molecular:404.47Histatin 5
CAS:<p>Histatin 5, a human saliva peptide, blocks MMP-2 and MMP-9 at IC50s of 0.57/0.25 μM and kills fungi.</p>Fórmula:C133H195N51O33Pureza:98%Forma y color:SolidPeso molecular:3036.29Aristololactam IIIa
CAS:<p>Aristololactam IIIa inhibits superoxide and elastase generation; IC50: 0.12 μg/mL and 0.20 μg/mL.</p>Fórmula:C16H9NO4Forma y color:SolidPeso molecular:279.25Imitrodast
CAS:<p>Imitrodast is a small molecule thromboxane A2 synthase (TXA2 synthase) inhibitor for the treatment of immune system disorders, respiratory disorders, and</p>Fórmula:C13H12N2O2SPureza:98.39%Forma y color:SolidPeso molecular:260.31AP-C2
CAS:<p>AP-C2 is a potent small molecule guanosine 3',5'-cyclic monophosphate (cGMP)-dependent protein kinase II (cGKII) inhibitor with a pIC50 of 5.2 for cGKII.</p>Fórmula:C18H16N4SPureza:99.87%Forma y color:SoildPeso molecular:320.41NS5A-IN-4
CAS:<p>NS5A-IN-4 (Compound 1.12) is a hepatitis C inhibitor effective against multiple genotypes, with IC50 values ranging from 1.2 to 2296 pM.</p>Fórmula:C47H48N8O6Forma y color:SolidPeso molecular:820.93Sucunamostat
CAS:<p>Sucunamostat is an L-aspartic acid enteropeptidase inhibitor.</p>Fórmula:C22H22N4O8Forma y color:SolidPeso molecular:470.438Plasma kallikrein-IN-1
CAS:<p>Plasma kallikrein-IN-1 is a PKK inhibitor with an IC 50 value of 0.5 nM.</p>Fórmula:C23H25F2N7OForma y color:SolidPeso molecular:453.498Sofosbuvir impurity J
CAS:<p>Sofosbuvir impurity J is an diastereoisomer of Sofosbuvir.Sofosbuvir is an HCV RNA replication inhibitor, with potent anti-hepatitis C virus activity.</p>Fórmula:C22H30FN4O8PPureza:98%Forma y color:SolidPeso molecular:528.47Acetyl-Calpastatin(184-210)(human)
CAS:<p>Calpain inhibitor, Ki 0.2 nM for calpain I/II, doesn't affect papain/trypsin/cat L. Raises Aβ42, Aβ40 secretion & Aβ42/Aβ40 ratio.</p>Fórmula:C142H230N36O44SPureza:98%Forma y color:SolidPeso molecular:3177.65Berotralstat
CAS:<p>Berotralstat (BCX7353) is an oral, low-toxicity, specific kallikrein inhibitor for hereditary angioedema research, blocking bradykinin release.</p>Fórmula:C30H26F4N6OForma y color:SolidPeso molecular:562.56PF 00356231
CAS:<p>PF 00356231 is a selectivity inhibitor MMP-12 and can be used in studies about the treatment of emphysema and chronic obstructive pulmonary disease (COPD).</p>Fórmula:C25H20N2O3SPureza:99.35%Forma y color:SolidPeso molecular:428.5Phaeosphaone D
CAS:<p>Phaeosphaone D, a thiodiketopiperazine from Phaeosphaeria fuckelii fungus, inhibits mushroom tyrosinase (IC50 = 33.2 μM).</p>Fórmula:C20H27N3O3S2Forma y color:SolidPeso molecular:421.58Sofosbuvir impurity A
CAS:<p>Sofosbuvir impurity A is an diastereoisomer of Sofosbuvir. Sofosbuvir is anHCV RNA replication inhibitor ,with potent anti-hepatitis C virus activity.</p>Fórmula:C22H29FN3O9PPureza:98%Forma y color:SolidPeso molecular:529.45HIV-1 inhibitor-6
CAS:<p>HIV-1 inhibitor-6 (3-Pyridinecarboxamide, 1,4-dihydro-1-methyl-N-(5-nitro-1,2-benzisothiazol-3-yl)-4-oxo-) is a potent HIV-1 pre-mRNA selective splicing</p>Fórmula:C14H10N4O4SPureza:99.33%Forma y color:SolidPeso molecular:330.32Nostosin G
<p>Nostosin G, a linear peptide with Hpla, Hty, and argininal, inhibits trypsin effectively (IC50 = 0.1 μM).</p>Fórmula:C25H33N5O6Forma y color:SolidPeso molecular:499.56BPHA
CAS:<p>BPHA is a selective oral inhibitor of MMP-2/9/14 (IC50: 12/16/17 nM), not affecting MMP-1/3/7, with anti-angiogenic and anti-tumor properties.</p>Fórmula:C21H20N2O4SPureza:99.44%Forma y color:SolidPeso molecular:396.46CRA-2059 hydrochloride
<p>CRA-2059 hydrochloride is a highly specific and selective tryptase inhibitor, with a Ki of 620 pM for recombinant human tryptase-β (rHTβ)[1][2].</p>Forma y color:SolidEnzyme-IN-1
CAS:<p>Enzyme-IN-1（compound 1）为基于肽的N端亲核试剂（Ntn）水解酶抑制剂，特别针对20S蛋白酶体的糜胰蛋白酶样活性（CT-L）进行抑制，可能展现出抗炎特性。</p>Fórmula:C36H50N4O7Forma y color:SolidPeso molecular:650.8Sadopeptins A
<p>Sadopeptins A, a natural product isolated from Streptomyces sp., is a potent proteasome inhibitor [1].</p>Fórmula:C49H71N9O13SForma y color:SolidPeso molecular:1026.21JC-10
CAS:<p>JC-10 is a potent inhibitor of metalloproteinases and is often used as a probe.</p>Fórmula:C25H29Cl2IN4Pureza:95%Forma y color:SolidPeso molecular:583.34Ellipyrone A
<p>Ellipyrone A: γ-pyrone macrocycle, inhibits DPP-4 (IC50=0.35mM), α-glucosidase (IC50=0.74mM), α-amylase (IC50=0.59mM).</p>Fórmula:C25H34O8Forma y color:SolidPeso molecular:462.53Leptosin D
CAS:<p>Leptosin D, a thiodiketopiperazine alkaloid derived from mushrooms, effectively inhibits tyrosinase activity, demonstrating an inhibition concentration (IC50)</p>Fórmula:C25H24N4O3S2Forma y color:SolidPeso molecular:492.61Cys-TAT(47-57) acetate(583836-55-9 Free base)
<p>Cys-TAT(47-57) acetate is derived from the HIV-1 transactivating protein. Cys-TAT(47-57) acetate is an arginine rich peptide that can penetrate cells.</p>Fórmula:C69H128N34O16SPureza:95.1100%Forma y color:SolidPeso molecular:1722.04CRA-2059 TFA
<p>CRA-2059 is a highly specific and selective tryptase inhibitor, with a Ki of 620 pM for recombinant human tryptase-β (rHTβ)[1][2].</p>Forma y color:SolidCL 82198 hydrochloride
CAS:<p>CL 82198 hydrochloride selectively inhibits MMP-13, not MMP-1/9/TACE, and blocks HP75 invasion and neurotoxicity in zebrafish.</p>Fórmula:C17H23ClN2O3Forma y color:SolidPeso molecular:338.83Nitidanin
<p>Nitidanin is a useful organic compound for research related to life sciences and the catalog number is T125599.</p>Fórmula:C21H24O8Forma y color:SolidPeso molecular:404.415RJS308
<p>RJS308 is a PROTAC degrader of cyclosporin A (cyclosporin A) with a DC50 of 284 nM. It exhibits antiviral activity by inhibiting the replication of HIV-1 and HCV. (Pink: ligand for target protein CypA ligand-2; Black: linker; Blue: ligand for E3 ligase VHL (S,R,S)-AHPC-Me)</p>Fórmula:C63H75N13O11SForma y color:SolidPeso molecular:1222.42N-CBZ-Phe-Arg-AMC TFA
<p>N-CBZ-Phe-Arg-AMC TFA (Z-FR-AMC TFA) is a fluorescent substrate for serine proteases. assess the activity of trypsin, plasmin, and cathepsin.</p>Fórmula:C35H37F3N6O8Pureza:99.88%Forma y color:SolidPeso molecular:726.7RXP470
CAS:<p>RXP470 is a potent and selective MMP-12 inhibitor (Ki 0.24 nM).</p>Fórmula:C35H35BrClN4O10PForma y color:SolidPeso molecular:818L 659286
CAS:<p>L 659286 is one kind of cephalosporin derivative.</p>Fórmula:C17H21N5O7S2Forma y color:SolidPeso molecular:471.51α 1(I) Collagen (614-639), human
CAS:<p>This is a peptide inhibitor of collagen fibrillar matrix assembly.</p>Fórmula:C134H189N37O39Pureza:98%Forma y color:SolidPeso molecular:2942.16Linagliptin Methyldimer
CAS:<p>Linagliptin Methyldimer is a potent dipeptidyl peptidase IV inhibitor, IC50=6 pM.</p>Fórmula:C50H56N16O4Pureza:97.23%Forma y color:SolidPeso molecular:945.08Alisporivir
CAS:<p>Alisporivir (Debio-025) is a cyclophilin A inhibitor that disrupts the interaction between CypA and NS5A. HCV activity in vivo and in vitro.</p>Fórmula:C63H113N11O12Pureza:99.95%Forma y color:SolidPeso molecular:1216.64Ecallantide TFA
<p>Ecallantide (DX-88) TFA, a specific recombinant plasma kallikrein inhibitor, directly inhibits bradykinin production and is indicated for the prevention of</p>Forma y color:Odour SolidObtusifolin-2-O-glucoside
CAS:<p>Obtusifolin-2-O-glucoside (compound 7), a tyrosinase inhibitor with an IC50 value of 9.2 μM, can be isolated from cassia seed [1].</p>Fórmula:C22H22O10Forma y color:SolidPeso molecular:446.4DPP8/9-IN-1
<p>DPP8/9-IN-1 (Compound 16) is a selective covalent inhibitor of dipeptidyl peptidase 8 and 9 (DPP8/9), with IC50 values of 14 nM and 298 nM, respectively. It irreversibly binds to the active site serine (such as S730 in DPP9) through a phosphate ester warhead, blocking substrate binding and inhibiting DPP8/9-mediated protein processing. DPP8/9-IN-1 holds potential for research in cancer and inflammatory diseases.</p>Forma y color:Odour SolidRecombinant Proteinase K
Recombinant Proteinase K: serine protease, cleaves carboxy-terminus peptides, digests proteins, purifies nucleic acids.Forma y color:SolidRivulariapeptolides 1155
<p>Rivulariapeptolides 1155 inhibits chymotrypsin (41.84 nM), elastase (4.94 nM), and proteinase K (56.54 nM).</p>Fórmula:C59H81N9O15Forma y color:SolidPeso molecular:1156.33Ac-DEMEEC-OH
CAS:<p>Ac-DEMEEC-OH is a competitive inhibitor of the HCV NS3 protease with a Ki of 0.6 µM.</p>Fórmula:C29H44N6O16S2Forma y color:SolidPeso molecular:796.82Relacatib
CAS:<p>Relacatib (SB-462795) is a potent cathepsins K, L, V inhibitor with high affinity (Ki: 41-68 pM) and reduces bone resorption effectively.</p>Fórmula:C27H32N4O6SForma y color:SolidPeso molecular:540.64
