Proteasas / Proteasoma
Los inhibidores de proteasas y proteasomas son compuestos que bloquean la actividad de las proteasas y del proteasoma, que están involucrados en la degradación y renovación de proteínas. Estos inhibidores son vitales para estudiar la regulación de la homeostasis proteica, el control del ciclo celular y la apoptosis. Los inhibidores de proteasas y proteasomas también se utilizan en el tratamiento de enfermedades como el cáncer, donde la degradación anormal de proteínas desempeña un papel en la progresión de la enfermedad. Al inhibir las proteasas o el proteasoma, estos compuestos pueden inducir la muerte celular en células cancerosas y son herramientas esenciales tanto en la investigación básica como en el desarrollo terapéutico. En CymitQuimica, ofrecemos una amplia gama de inhibidores de proteasas y proteasomas de alta calidad para apoyar su investigación en bioquímica, biología celular y desarrollo de fármacos.
Subcategorías de "Proteasas / Proteasoma"
- Acetil-CoA Carboxilasa(35 productos)
- Cisteína proteasa(96 productos)
- DPP-4(20 productos)
- Glutaminasa(40 productos)
- Proteasa del VIH(451 productos)
- PAI-1(25 productos)
- Inhibidores de la proteasa(50 productos)
- Receptor activado por proteasa(53 productos)
- Proteasoma(94 productos)
- Serina proteasa(49 productos)
- p97(14 productos)
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Se han encontrado 1039 productos de "Proteasas / Proteasoma"
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Fibrinopeptide B, human
CAS:<p>Fibrinopeptide B (FPB) is produced during the cleavage of fibrinogen, by thrombin, to fibrin monomer.</p>Fórmula:C66H93N19O25Pureza:98%Forma y color:SolidPeso molecular:1552.56Succinyl-(Pro58,D-Glu65)-Hirudin (56-65) (sulfated)
CAS:<p>Succinyl-(Pro58,D-Glu65)-Hirudin (56-65) (sulfated) is a hirugen-like peptide with greater thrombin affinity than Hirugen, exhibiting a dissociation constant (K</p>Fórmula:C64H88N10O26SPureza:98%Forma y color:SolidPeso molecular:1445.5Patamostat HCl
CAS:<p>Patamostat HCl is a highly potent and selective small molecule protease (protease) inhibitor that inhibits trypsin, fibrinolytic enzymes, and thrombin with IC50</p>Fórmula:C20H21ClN4O4SPureza:99.15% - 99.76%Forma y color:SoildPeso molecular:448.92HCVP-IN-1
CAS:<p>HCVP-IN-1 (compound 1) is a hepatitis C viral polymerase (HCVP) inhibitor.</p>Fórmula:C30H34FN5O3Forma y color:SolidPeso molecular:531.632PSI-353661
CAS:<p>PSI-353661 (GS-558093), inhibits HCV's NS5B polymerase; EC90: 8nM (wild-type), 11nM (S282T); active in human hepatocytes.</p>Fórmula:C24H32FN6O8PForma y color:SolidPeso molecular:582.52CRA-2059
CAS:<p>CRA-2059 is a potent and selective inhibitor of tryptase, particularly targeting recombinant human tryptase-β (rHTβ), with a K i of 620 pM.</p>Fórmula:C34H46N12O8Pureza:97.68%Forma y color:SolidPeso molecular:750.818Ac-[Nle4,D-Phe7]-α-MSH (4-10)-NH2
CAS:Ac-[Nle4,D-Phe7]-α-MSH (4-10)-NH2, a melanotropin derivative and melanocyte-stimulating hormone, activates tyrosinase and demonstrates a thermoregulatory effectFórmula:C47H64N14O10Forma y color:SolidPeso molecular:985.1Enzyme-IN-1
CAS:<p>Enzyme-IN-1（compound 1）为基于肽的N端亲核试剂（Ntn）水解酶抑制剂，特别针对20S蛋白酶体的糜胰蛋白酶样活性（CT-L）进行抑制，可能展现出抗炎特性。</p>Fórmula:C36H50N4O7Forma y color:SolidPeso molecular:650.8APC-6860
CAS:<p>APC-6860, a serine protease inhibitor, targets multiple enzymes; most potent against human urokinase (Ki: 0.1 µM). Used in cancer research.</p>Fórmula:C9H7IN2SForma y color:SolidPeso molecular:302.13PS 915
CAS:<p>PS 915 is a substrate for colorimetric assay. It was used for plasma antithrombin.</p>Fórmula:C27H36ClN7O6Pureza:98%Forma y color:SolidPeso molecular:590.08Ichorcumab
CAS:<p>Ichorcumab (JNJ-375) is a fully human IgG4 antibody that targets thrombin. It binds to exosite 1 of thrombin, inhibiting substrate binding without affecting its catalytic activity. For isotype control, refer to HumanIgG1kappa, Isotype Control.</p>Forma y color:LiquidKKI-5
CAS:<p>KKI 5: Serine protease inhibitor, blocks kallikrein & plasmin, potential for cancer therapy & angioedema treatment.</p>Fórmula:C35H55N11O9Pureza:98%Forma y color:SolidPeso molecular:773.88Rivulariapeptolides 1121
<p>Rivulariapeptolides 1121 inhibits serine proteases: chymotrypsin (IC50=35.52 nM), elastase (13.24 nM), proteinase K (48.05 nM).</p>Fórmula:C56H83N9O15Forma y color:SolidPeso molecular:1122.31Relacatib
CAS:<p>Relacatib (SB-462795) is a potent cathepsins K, L, V inhibitor with high affinity (Ki: 41-68 pM) and reduces bone resorption effectively.</p>Fórmula:C27H32N4O6SForma y color:SolidPeso molecular:540.64AL-611
CAS:<p>AL-611 is an HCV NS5B polymerase inhibitor ( EC 50 = 5 nM).</p>Fórmula:C25H33F2N6O8PForma y color:SolidPeso molecular:614.544DPP-4-IN-14
<p>DPP-4-IN-14 (compound 30) is an inhibitor of DPP-4, with an IC50 value of 12.82 nM.</p>Fórmula:C33H27N7O3Forma y color:SolidPeso molecular:569.613Carboxypeptidase C
CAS:<p>Carboxypeptidase C removes COOH-terminal amino acids and others in peptides for biochemical studies.</p>Forma y color:SolidTyrosinase-IN-38
<p>Tyrosinase-IN-38 (compound 6b) is a competitive inhibitor of tyrosinase, demonstrating an IC50 of 25.82 μM and exhibits antioxidant activity.</p>Forma y color:Odour SolidPPACK II
CAS:<p>PPACK II is an irreversible and specific glandular and plasma kallikreins inhibitor [1] .</p>Fórmula:C25H33ClN6O3Forma y color:SolidPeso molecular:501.02Fotagliptin
CAS:<p>Fotagliptin is a dipeptidyl peptidase IV inhibitor.</p>Fórmula:C17H19FN6OForma y color:SolidPeso molecular:342.37Sofosbuvir impurity H
<p>Sofosbuvir impurity H, an diastereoisomer of Sofosbuvir, is the impurity of Sofosbuvir.</p>Fórmula:C29H33FN3O10PPureza:98%Forma y color:SolidPeso molecular:633.56Sitagliptin fenilalanil hydrochloride
CAS:<p>Sitagliptin phenylalanine hydrochloride, a dipeptidyl peptidase-4 (DPP-4) inhibitor [1], is a chemical compound utilized in medical applications.</p>Fórmula:C25H25ClF6N6O2Forma y color:SolidPeso molecular:590.95ADAM8-IN-1
CAS:<p>ADAM8-IN-1 is a potent ADAM8 inhibitor with an IC 50 value of 73 nM.</p>Fórmula:C44H44Br4N6O12S2Forma y color:SolidPeso molecular:1232.6STK33-IN-1
CAS:<p>STK33-IN-1 (compound 1) is a STK33 inhibitor, with an IC 50 of 7 nM.</p>Fórmula:C24H27N7O2Forma y color:SolidPeso molecular:445.527Procizumab
<p>Procizumab is a humanized IgG1 antibody that targets dipeptidyl peptidase 3 (DPP3). It shows potential for investigating sepsis. For the isotype control, refer to HumanIgG1kappa, Isotype Control.</p>Forma y color:Odour LiquidHepcidin-1 (mouse)
CAS:<p>Hepcidin-1 (mouse) is a peptide hormone that regulates iron balance, elevates mRNA for TRAP, cathepsin K, and MMP-9, and promotes TRAP-5b protein secretion.</p>Fórmula:C111H169N31O35S8Forma y color:SolidPeso molecular:2754.24Apovincamine
CAS:<p>Apovincamine is a vinca alkaloid and a chemical precursor of Vinpocetine, which is a derivative of Vincamine with vasodilating activity.</p>Fórmula:C21H24N2O2Pureza:98%Forma y color:SolidPeso molecular:336.44Nostopeptin B
CAS:<p>Nostopeptin B is an inhibitor of elastase.</p>Fórmula:C46H70N8O12Forma y color:SolidPeso molecular:927.11(-)-Sitagliptin Carbamoyl Glucuronide
CAS:<p>Minor phase II metabolite of DPP-4 inhibitor sitagliptin, found in rat and dog plasma.</p>Fórmula:C23H23F6N5O9Forma y color:SolidPeso molecular:627.4537-Methoxy obtusifolin
CAS:<p>7-Methoxy obtusifolin (Compound 4) is a chemical compound that acts as a competitive inhibitor of the enzyme tyrosinase, displaying an inhibitory concentration</p>Fórmula:C17H14O6Forma y color:SolidPeso molecular:314.29Phaeosphaone D
CAS:<p>Phaeosphaone D, a thiodiketopiperazine from Phaeosphaeria fuckelii fungus, inhibits mushroom tyrosinase (IC50 = 33.2 μM).</p>Fórmula:C20H27N3O3S2Forma y color:SolidPeso molecular:421.58Ac-VDQQD-pNA
CAS:<p>Ac-VDQQD-pNA serves as a substrate for Caspase 2, which cleaves it to yield the yellow compound pNA (p-nitroaniline).</p>Fórmula:C31H43N9O14Forma y color:SolidPeso molecular:765.73MMP-9-IN-6
CAS:<p>MMP-9-IN-6: MMP-9 inhibitor, IC50 of 50 µM, anti-ulcer, potential anti-tumor, for tissue repair studies.</p>Fórmula:C25H19NO2Pureza:99.75%Forma y color:SoildPeso molecular:365.42Dutogliptin tartrate
CAS:Dutogliptin tartrate is an effective and selective oral dipeptide-peptide-4 (DPP4) inhibitor for the treatment of type 2 diabetes mellitus.Fórmula:C14H26BN3O9Pureza:98%Forma y color:SolidPeso molecular:391.18Histatin 5 (TFA)(115966-68-2,free)
Histatin 5 (TFA)(115966-68-2,free) (Histatin 5 (TFA)) inhibits the activity of the host matrix metalloproteinases MMP-2 and MMP-9 with IC50s of 0.57 and 0.25 μMFórmula:C135H196F3N51O35Pureza:98%Forma y color:SolidPeso molecular:3150.32CTTHWGFTLC, CYCLIC
CAS:CTT Gelatinase Inhibitor peptide blocks MMP-2/9, hindering cancer by stopping tumor growth.Fórmula:C52H71N13O14S2Pureza:98%Forma y color:SolidPeso molecular:1166.33Ac-PLVE-FMK
CAS:<p>Ac-PLVE-FMK (Ac-Pro-Leu-Val-Glu(OMe)-CH2F), a tetrapeptidyl fluoromethylketone (FMKs), serves as a cathepsin inhibitor. It is utilized in cancer research [1].</p>Fórmula:C25H41FN4O7Pureza:98%Forma y color:SolidPeso molecular:528.61MMP-2 Inhibitor-4
<p>MMP-2Inhibitor-4 (Compound 5g) is an MMP-2 inhibitor with an IC50 of 152.62 nM. It effectively reduces MMP-2 levels in K562 cell lines by stably binding to the active site of MMP-2 and exhibits strong anti-angiogenic effects in ACHN cell lines. MMP-2Inhibitor-4 shows potential for research in chronic myelogenous leukemia (CML).</p>Fórmula:C19H23N3O5SForma y color:SolidPeso molecular:405.468Tyrosinase-IN-34
<p>Tyrosinase-IN-34 (compound 5a), a human tyrosinase inhibitor (IC 50: 3.5 μM), shows promise in regulating melanogenesis and pigmentation.</p>Fórmula:C19H14BrClN4OForma y color:SolidPeso molecular:429.7Rivulariapeptolides 1155
<p>Rivulariapeptolides 1155 inhibits chymotrypsin (41.84 nM), elastase (4.94 nM), and proteinase K (56.54 nM).</p>Fórmula:C59H81N9O15Forma y color:SolidPeso molecular:1156.33RXP470
CAS:<p>RXP470 is a potent and selective MMP-12 inhibitor (Ki 0.24 nM).</p>Fórmula:C35H35BrClN4O10PForma y color:SolidPeso molecular:818H-Gly-Pro-Hyp-OH
CAS:<p>H-Gly-Pro-Hyp-OH is a potent and oral anti-photoaging collagen peptide and improves the hydration of human skin, elasticity and anti-wrinkle properties.</p>Fórmula:C12H19N3O5Pureza:98.47%Forma y color:SolidPeso molecular:285.3LMP7/LMP2-IN-1
CAS:<p>LMP7/LMP2-IN-1 (Compound 19) is an orally effective inhibitor targeting the immunoproteasome subunits LMP7 and LMP2, with respective IC50 values of 257 and 10 nM. This compound reduces the production of antibodies and downregulates the B cells in the germinal centers of the spleen and plasma cells in NP-OVA immunized mice. It has potential applications in the study of autoimmune diseases.</p>Fórmula:C16H27BN4O3Forma y color:SoildPeso molecular:334.22BMS-767778
CAS:<p>BMS-767778, a DPP-4 inhibitor, is used potentially for the treatment of type 2 diabetes.</p>Fórmula:C19H20Cl2N4O2Forma y color:SolidPeso molecular:407.29Nitidanin
<p>Nitidanin is a useful organic compound for research related to life sciences and the catalog number is T125599.</p>Fórmula:C21H24O8Forma y color:SolidPeso molecular:404.415NVP-DPP728 dihydrochloride
CAS:<p>NVP-DPP728 dihydrochloride is a potent, selective DPP-IV inhibitor with a Ki of 11 nM, useful in diabetes research.</p>Fórmula:C15H20Cl2N6OForma y color:SolidPeso molecular:371.27Leptosphaerodione
CAS:Leptosphaerodione from Remotididymella sp.: a potent UPS inhibitor with 3.2 μM IC50 in HeLa cells; anti-tumor.Fórmula:C21H22O5Forma y color:SolidPeso molecular:354.4DPP8/9-IN-1
<p>DPP8/9-IN-1 (Compound 16) is a selective covalent inhibitor of dipeptidyl peptidase 8 and 9 (DPP8/9), with IC50 values of 14 nM and 298 nM, respectively. It irreversibly binds to the active site serine (such as S730 in DPP9) through a phosphate ester warhead, blocking substrate binding and inhibiting DPP8/9-mediated protein processing. DPP8/9-IN-1 holds potential for research in cancer and inflammatory diseases.</p>Forma y color:Odour SolidBictegravir Sodium
CAS:<p>Bictegravir Sodium is an HIV-1 integrase inhibitor with 7.5 nM IC50, offering strong, selective anti-HIV effects and minimal toxicity.</p>Fórmula:C21H17F3N3NaO5Pureza:99.97%Forma y color:SolidPeso molecular:471.36Cyanopeptolin 954
CAS:<p>Cyanopeptolin 954 is a chlorine-containing Microcystis aeruginosa NIVA Cya 43 chymotrypsin Inhibitor.</p>Fórmula:C46H63ClN8O12Pureza:98%Forma y color:SolidPeso molecular:955.5
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