Proteasas / Proteasoma
Los inhibidores de proteasas y proteasomas son compuestos que bloquean la actividad de las proteasas y del proteasoma, que están involucrados en la degradación y renovación de proteínas. Estos inhibidores son vitales para estudiar la regulación de la homeostasis proteica, el control del ciclo celular y la apoptosis. Los inhibidores de proteasas y proteasomas también se utilizan en el tratamiento de enfermedades como el cáncer, donde la degradación anormal de proteínas desempeña un papel en la progresión de la enfermedad. Al inhibir las proteasas o el proteasoma, estos compuestos pueden inducir la muerte celular en células cancerosas y son herramientas esenciales tanto en la investigación básica como en el desarrollo terapéutico. En CymitQuimica, ofrecemos una amplia gama de inhibidores de proteasas y proteasomas de alta calidad para apoyar su investigación en bioquímica, biología celular y desarrollo de fármacos.
Subcategorías de "Proteasas / Proteasoma"
- Acetil-CoA Carboxilasa(36 productos)
- Cisteína proteasa(110 productos)
- DPP-4(20 productos)
- Glutaminasa(44 productos)
- Proteasa del VIH(507 productos)
- PAI-1(26 productos)
- Inhibidores de la proteasa(50 productos)
- Receptor activado por proteasa(54 productos)
- Proteasoma(95 productos)
- Serina proteasa(56 productos)
- p97(15 productos)
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Se han encontrado 1094 productos de "Proteasas / Proteasoma"
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Phepropeptin C
CAS:Phepropeptin C is a microbial secondary metabolite that acts as a proteasome (proteasome) inhibitor, with an IC50 of 12.5 μg/mL.Fórmula:C38H60N6O6Forma y color:SolidPeso molecular:696.92Ellipyrone A
Ellipyrone A: γ-pyrone macrocycle, inhibits DPP-4 (IC50=0.35mM), α-glucosidase (IC50=0.74mM), α-amylase (IC50=0.59mM).Fórmula:C25H34O8Forma y color:SolidPeso molecular:462.53Leptosin D
CAS:Leptosin D, a thiodiketopiperazine alkaloid derived from mushrooms, effectively inhibits tyrosinase activity, demonstrating an inhibition concentration (IC50)Fórmula:C25H24N4O3S2Forma y color:SolidPeso molecular:492.61AP-C2
CAS:AP-C2 is a potent small molecule guanosine 3',5'-cyclic monophosphate (cGMP)-dependent protein kinase II (cGKII) inhibitor with a pIC50 of 5.2 for cGKII.Fórmula:C18H16N4SPureza:99.99%Forma y color:SoildPeso molecular:320.41Ac-DEMEEC-OH
CAS:Ac-DEMEEC-OH is a competitive inhibitor of the HCV NS3 protease with a Ki of 0.6 µM.Fórmula:C29H44N6O16S2Forma y color:SolidPeso molecular:796.82Sadopeptins A
Sadopeptins A, a natural product isolated from Streptomyces sp., is a potent proteasome inhibitor [1].Fórmula:C49H71N9O13SForma y color:SolidPeso molecular:1026.21C-telopeptide
CAS:C-telopeptide from type I collagen is released during bone resorption; it correlates with bone mineral density.Fórmula:C34H56N14O13Pureza:98%Forma y color:SolidPeso molecular:868.9Peptide 74
CAS:Peptide 74 is a synthetic peptide. It also inhibits the activated form of this enzyme.Fórmula:C62H107N23O20S2Pureza:98%Forma y color:SolidPeso molecular:1558.79Aristololactam IIIa
CAS:Aristololactam IIIa inhibits superoxide and elastase generation; IC50: 0.12 μg/mL and 0.20 μg/mL.Fórmula:C16H9NO4Forma y color:SolidPeso molecular:279.25Enzyme-IN-1
CAS:Enzyme-IN-1（compound 1）为基于肽的N端亲核试剂（Ntn）水解酶抑制剂，特别针对20S蛋白酶体的糜胰蛋白酶样活性（CT-L）进行抑制，可能展现出抗炎特性。Fórmula:C36H50N4O7Forma y color:SolidPeso molecular:650.86,6′-Dihydroxythiobinupharidine
CAS:6,6′-Dihydroxythiobinupharidine, a cysteine proteases inhibitor, amplifies DNA cleavage facilitated by human topoisomerase IIα and IIβ by approximately 8-foldFórmula:C30H42N2O4SForma y color:SolidPeso molecular:526.73CTTHWGFTLC, CYCLIC
CAS:CTT Gelatinase Inhibitor peptide blocks MMP-2/9, hindering cancer by stopping tumor growth.Fórmula:C52H71N13O14S2Pureza:98%Forma y color:SolidPeso molecular:1166.33Paritaprevir dihydrate
CAS:Paritaprevir dihydrate: potent oral HCV NS3/4A inhibitor (EC50: 0.21-1 nM), SARS-CoV-3CL blocker (IC50: 1.31 μM), metabolized by CYP3A, boosted by Ritonavir.Fórmula:C40H47N7O9SForma y color:SolidPeso molecular:801.91Rivulariapeptolides 988
Rivulariapeptolides 988 inhibits serine proteases: chymotrypsin (IC50 = 95.46 nM), elastase (15.29 nM), proteinase K (85.50 nM).Fórmula:C50H68N8O13Forma y color:SolidPeso molecular:989.12Dnp-P-Cha-G-Cys(Me)-HA-K(Nma)-NH2
CAS:Dnp-P-Cha-G-Cys(Me)-HA-K(Nma)-NH2 is a fluorogenic probe for MMP-1 and MMP-9 detection, releasing fluorescent Nma upon cleavage (Ex/Em: 340/440 nm).Fórmula:C49H68N14O12SForma y color:SolidPeso molecular:1077.22Grazoprevir potassium salt
CAS:<p>Grazoprevir, a drug for hepatitis C, is a second-gen NS3/4a protease inhibitor.</p>Fórmula:C38H49KN6O9SForma y color:SolidPeso molecular:80515,16-Dihydrotanshindiol C
15,16-Dihydrotanshindiol C is a useful organic compound for research related to life sciences and the catalog number is T123985.Fórmula:C18H18O5Forma y color:SolidPeso molecular:314.337DPP8/9-IN-1
DPP8/9-IN-1 (Compound 16) is a selective covalent inhibitor of dipeptidyl peptidase 8 and 9 (DPP8/9), with IC50 values of 14 nM and 298 nM, respectively. It irreversibly binds to the active site serine (such as S730 in DPP9) through a phosphate ester warhead, blocking substrate binding and inhibiting DPP8/9-mediated protein processing. DPP8/9-IN-1 holds potential for research in cancer and inflammatory diseases.Forma y color:Odour SolidPirmitegravir
CAS:<p>Pirmitegravir (STP0404) is a potent ALLINI, blocks LEDGF/p75 site, shows antiviral action against HIV.</p>Fórmula:C27H31ClN4O3Pureza:99.79% - 99.79%Forma y color:SolidPeso molecular:495.01H-Gly-Arg-pNA dihydrochloride
CAS:H-Gly-Arg-pNA 2HCl, a peptide, binds 1,2 thrombin; colorimetric quantification at 405 nm indicates thrombin activity.Fórmula:C14H23Cl2N7O4Pureza:99.14%Forma y color:SolidPeso molecular:424.28
