Proteasas / Proteasoma
Los inhibidores de proteasas y proteasomas son compuestos que bloquean la actividad de las proteasas y del proteasoma, que están involucrados en la degradación y renovación de proteínas. Estos inhibidores son vitales para estudiar la regulación de la homeostasis proteica, el control del ciclo celular y la apoptosis. Los inhibidores de proteasas y proteasomas también se utilizan en el tratamiento de enfermedades como el cáncer, donde la degradación anormal de proteínas desempeña un papel en la progresión de la enfermedad. Al inhibir las proteasas o el proteasoma, estos compuestos pueden inducir la muerte celular en células cancerosas y son herramientas esenciales tanto en la investigación básica como en el desarrollo terapéutico. En CymitQuimica, ofrecemos una amplia gama de inhibidores de proteasas y proteasomas de alta calidad para apoyar su investigación en bioquímica, biología celular y desarrollo de fármacos.
Subcategorías de "Proteasas / Proteasoma"
- Acetil-CoA Carboxilasa(36 productos)
- Cisteína proteasa(110 productos)
- DPP-4(24 productos)
- Glutaminasa(44 productos)
- Proteasa del VIH(497 productos)
- PAI-1(26 productos)
- Inhibidores de la proteasa(50 productos)
- Receptor activado por proteasa(54 productos)
- Proteasoma(90 productos)
- Serina proteasa(51 productos)
- p97(15 productos)
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Se han encontrado 1009 productos de "Proteasas / Proteasoma"
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AGG-523
CAS:AGG-523, an aggrecanase inhibitor, may slow cartilage wear after joint injury by reducing ARG-aggrecan in rats.Fórmula:C28H29FN2O4Forma y color:SolidPeso molecular:476.54Cysteine Protease inhibitor
CAS:Cysteine protease inhibitors are inhibitors of cysteine proteases. Target: Cysteine ProteaseFórmula:C18H14N4OPureza:98%Forma y color:SolidPeso molecular:302.33Elastase-IN-1
CAS:Elastase-IN-1 (Compound Q11) is a non-toxic elastase inhibitor with an IC 50 of 0.897 μM [1].Fórmula:C17H12N4O3Forma y color:SolidPeso molecular:320.3Plasma kallikrein-IN-3
CAS:Plasma kallikrein-IN-3 is a potent inhibitor (IC50: 0.15 μM) used in hereditary angioedema and diabetic eye disease research.Fórmula:C20H23N5O2Forma y color:SolidPeso molecular:365.43p-APMSF (hydrochloride)
CAS:p-APMSF irreversibly inhibits several serine proteases; Ki: 1.02-1.54 μM; selective over chymotrypsin and acetylcholinesterase.Fórmula:C8H10ClFN2O2SForma y color:SolidPeso molecular:252.69HCV-IN-3
CAS:HCV-IN-3 is a hepatitis C virus (HCV) NS3/4a protein inhibitor (IC50: 20 μM; Kd: 29 μM).Fórmula:C13H11F2NOPureza:98%Forma y color:SolidPeso molecular:235.23GM 1489
CAS:GM 1489 is an MMP inhibitor, effective against MMP-1, -2, -3, -8, -9, reduces cancer cell invasion, and prevents ear thickening in mice.Fórmula:C27H33N3O4Forma y color:SolidPeso molecular:463.57MMP2-IN-2
CAS:MMP2-IN-2 is an MMP-2 inhibitor that inhibits MMP-13, MMP-9, and MMP-8, and can be used in the study of cancer and immune diseases.Fórmula:C13H8N4O4Pureza:98.09%Forma y color:SolidPeso molecular:284.23PF-06279794
CAS:PF-06279794 is a potent, selective and ATP-competitive TNIK inhibitor.Fórmula:C22H20N4OForma y color:SolidPeso molecular:356.42Cathepsin L/S-IN-1
Cathepsin L/S-IN-1 inhibits Cathepsin L & S (IC50: 4.10 & 1.79 μM) and reduces metastasis in pancreatic cancer cells.Fórmula:C29H33BrN4O4SForma y color:SolidPeso molecular:613.57Ro 09-1679
CAS:Ro 09-1679 is a thrombin inhibitor.Fórmula:C22H39N9O6Pureza:98%Forma y color:SolidPeso molecular:525.6ABT-518
CAS:ABT-518 is an inhibitor of matrix metalloproteinases, which are associated with tumor growth and development of metastasis.Fórmula:C21H22F3NO8SForma y color:SolidPeso molecular:505.46ACH-806
CAS:ACH-806 is an NS4A antagonist. It can inhibit Hepatitis C Virus (HCV) replication with an EC50 of 14 nM.Fórmula:C19H20F3N3O2SPureza:98%Forma y color:SolidPeso molecular:411.44JPM-OEt
CAS:JPM-OEt: broad-spectrum, covalent cysteine cathepsin inhibitor with antitumor effects.Fórmula:C20H28N2O6Pureza:98%Forma y color:SolidPeso molecular:392.45Gemigliptin Tartrate(911637-19-9 free base)
CAS:Gemigliptin Tartrate (LC15-0444 tartrate) is a highly selective, reversible and competitive inhibitor of dipeptidyl peptidase-4 (DPP-4).Fórmula:C22H25F8N5O8Pureza:>99.99%Forma y color:SolidPeso molecular:639.45Tanomastat
CAS:Tanomastat is an orally bioavailable and non-peptidic biphenyl matrix metalloproteinases inhibitor.Fórmula:C23H19ClO3SPureza:98%Forma y color:SolidPeso molecular:410.91Grazoprevir sodium salt
CAS:Grazoprevir sodium salt is a selective Hepatitis C virus NS3/4a protease inhibitor with broad activity across genotypes and resistant variants.Fórmula:C38H50N6NaO9SPureza:98%Forma y color:SolidPeso molecular:789.9AGLME
CAS:AGLME is used in a direct enzymatic assay for activated Hageman factor measuring the ability of Hageman factor to hydrolyze the cpd.Fórmula:C11H21N3O4Forma y color:SolidPeso molecular:259.3Prodipine hydrochloride
CAS:Prodipine hydrochloride for purified and plasma Dipeptidyl peptidase IV (DPP IV) from the rabbit (IC50 of 4.5 μM and 30 μM, respectively).Fórmula:C20H26ClNPureza:98%Forma y color:SolidPeso molecular:315.88DTS
CAS:DTS is a selective and isoform-specific RSK1 kinase inhibitor. It also has broad cancer therapeutic potential.Fórmula:C14H14S3Pureza:98%Forma y color:SolidPeso molecular:278.46
