Proteasoma
Los inhibidores del proteasoma son compuestos que inhiben el proteasoma, un gran complejo proteico responsable de degradar proteínas no deseadas o dañadas dentro de la célula. La inhibición del proteasoma conduce a la acumulación de proteínas, lo que puede inducir la detención del ciclo celular y la apoptosis, especialmente en células que se dividen rápidamente, como las células cancerosas. Los inhibidores del proteasoma son cruciales en la investigación y terapia contra el cáncer, especialmente en el tratamiento del mieloma múltiple y otras malignidades hematológicas. En CymitQuimica, ofrecemos inhibidores del proteasoma para apoyar su investigación en oncología, biología celular y desarrollo de fármacos.
Se han encontrado 94 productos de "Proteasoma"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
Alloxan monohydrate
CAS:<p>Alloxan Monohydrate is a glucose analog used to induce diabetes by destroying beta-cells.</p>Fórmula:C4H4N2O5Pureza:99.01% - 99.42%Forma y color:Off-White To Beige-Yellowish Crystalline PowderPeso molecular:160.09ARV-471
CAS:<p>ARV-471 (Vepdegestrant) is a orally active Cereblon -based estrogen receptor (ER) PROTAC degrader. ARV-471 is developed for the research of breast cancer.</p>Fórmula:C45H49N5O4Pureza:97.15% - >99.99%Forma y color:SolidPeso molecular:723.9Omarigliptin
CAS:<p>Omarigliptin is a potent and selective oral dipeptidyl peptidase 4 (DPP4) inhibitor with IC50 value of 1.6 nM. Cost-effective and quality-assured.</p>Fórmula:C17H20F2N4O3SPureza:99.68% - 99.77%Forma y color:SolidPeso molecular:398.43Calpeptin
CAS:<p>Calpeptin is a potent, cell-permeable calpain inhibitor.</p>Fórmula:C20H30N2O4Pureza:97.06% - 98.33%Forma y color:White To Off-White PowderPeso molecular:362.46Talabostat mesylate
CAS:<p>Talabostat mesylate (PT100): Oral DPP4 inhibitor, IC50 0.18 nM, targets tumor-linked proteins, boosts hematopoiesis.</p>Fórmula:C10H23BN2O6SPureza:98% - 99.91%Forma y color:SolidPeso molecular:310.18PI-1840
CAS:<p>PI-1840 is a reversible and selective chymotrypsin-like (CT-L) inhibitor, with little proteasome proteolytic effects on trypsin-like (T-L) and PGPH-L.</p>Fórmula:C22H26N4O3Pureza:98.82%Forma y color:SolidPeso molecular:394.474'-Hydroxychalcone
CAS:<p>4'-Hydroxychalcone (2-Benzal-4-Hydroxyacetophenone) is a chalcone metabolite with hepatoprotective activity</p>Fórmula:C15H12O2Pureza:99.86% - 99.87%Forma y color:Yellow-Cream PowderPeso molecular:224.25ONX-0914
CAS:<p>ONX-0914 (PR-957) is an effective and specific immunoproteasome inhibitor, which has minimal cross-reactivity for the constitutive proteasome.</p>Fórmula:C31H40N4O7Pureza:98.24% - 99.31%Forma y color:SolidPeso molecular:580.67Bortezomib
CAS:<p>Bortezomib (LDP 341) is a 20S proteasome inhibitor (Ki=0.6 nM) that is reversible and selective.</p>Fórmula:C19H25BN4O4Pureza:97.79% - >99.99%Forma y color:Yellow SolidPeso molecular:384.24Epoxomicin
CAS:<p>Epoxomicin, a selective proteasome inhibitor, chiefly blocks CH-L activity, mildly affecting T-L and PGPH at lower rates.</p>Fórmula:C28H50N4O7Pureza:98.65% - 98.86%Forma y color:White To Off-White SolidPeso molecular:554.72Carfilzomib
CAS:<p>Carfilzomib (PR-171) is a proteasome inhibitor that irreversibly binds to the chymotrypsin of the 20S proteasome.</p>Fórmula:C40H57N5O7Pureza:99.6% - 99.84%Forma y color:SolidPeso molecular:719.91MDL-28170
CAS:<p>MDL-28170 (Calpain Inhibitor III) is a Cysteine protease.</p>Fórmula:C22H26N2O4Pureza:95.06%Forma y color:SolidPeso molecular:382.45ISOGINKGETIN
CAS:<p>ISOGINKGETIN (4',4'''-Dimethylamentoflavone), a compound derived from the leaves of Ginkgo biloba, to up-regulate adiponectin secretion.</p>Fórmula:C32H22O10Pureza:98% - 99.72%Forma y color:SolidPeso molecular:566.51Oprozomib
CAS:<p>Oprozomib inhibits 20S proteasome β5/LMP7, is orally available, and may have cancer-fighting properties. IC50: β5 - 36 nM; LMP7 - 82 nM.</p>Fórmula:C25H32N4O7SPureza:98% - 99.87%Forma y color:SolidPeso molecular:532.61UAMC00039 dihydrochloride
CAS:<p>UAMC00039 dihydrochloride is a potent, reversible and competitive dipeptidyl peptidase II inhibitor with an IC50 of 0.48 nM.</p>Fórmula:C16H26Cl3N3OPureza:>99.99%Forma y color:SolidPeso molecular:382.76MUN57694
CAS:<p>MUN57694 is an inhibitor of 26S proteasome.</p>Fórmula:C23H25N3O4Pureza:99%Forma y color:SolidPeso molecular:407.46Saxagliptin
CAS:<p>Saxagliptin (BMS-477118) is a selective and reversible DPP4 inhibitor with IC50 of 26 nM.</p>Fórmula:C18H25N3O2Pureza:99.17% - 99.95%Forma y color:SolidPeso molecular:315.41Tomatine
CAS:<p>Tomatine (lycopersicin) is an antiproliferatve agent of breast adenocarcinoma cells.</p>Fórmula:C50H83NO21Pureza:98.42% - 99.94%Forma y color:White To Light YellowPeso molecular:1034.19MG-101
CAS:<p>MG-101 (Calpain inhibitor I) is a cell-permeable and potent inhibitor of cysteine proteases including calpains and lysosomal cathepsins.</p>Fórmula:C20H37N3O4Pureza:98% - ≥98%Forma y color:SolidPeso molecular:383.53Bortezomib-pinanediol
CAS:<p>Bortezomib-pinanediol is a proteasome inhibitor. is a prodrug of Bortezomib.</p>Fórmula:C29H39BN4O4Pureza:97.5%Forma y color:Yellow SolidPeso molecular:518.46
