Células madre y Derivados
Los inhibidores de células madre son compuestos que se dirigen específicamente a las vías de señalización y proteínas involucradas en el mantenimiento, diferenciación y proliferación de células madre. Estos inhibidores son cruciales para comprender la biología de las células madre y para desarrollar estrategias que permitan manipularlas con fines terapéuticos, como en la medicina regenerativa y el tratamiento del cáncer. Al controlar el destino de las células madre, estos inhibidores pueden ayudar a guiar la diferenciación de células madre en tipos celulares específicos o prevenir el crecimiento celular no deseado. En CymitQuimica, ofrecemos una selección de inhibidores de células madre de alta calidad para apoyar su investigación en biología de células madre, biología del desarrollo y medicina regenerativa.
Subcategorías de "Células madre y Derivados"
- Gamma-secretasa(63 productos)
- Hedgehog / Smoothened(49 productos)
- Hippo pathway(7 productos)
- JAK(243 productos)
- Porcupine (Puerco espín)(9 productos)
- ROCK(61 productos)
- STAT(100 productos)
- Células madre(187 productos)
- TGF-beta / Smad(60 productos)
- Wnt / beta-catenina(61 productos)
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Se han encontrado 471 productos de "Células madre y Derivados"
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JAK3/BTK-IN-2
CAS:JAK3/ BTk-in-2 is a potent JAK3/BTK inhibitor.
Fórmula:C25H32N8O2Pureza:99.64% - 99.87%Forma y color:SolidPeso molecular:476.57EP009
CAS:EP009, a novel, selective, and orally active inhibitor of JAK3, induces therapeutic response in T-cell malignancies.Fórmula:C14H24O2Forma y color:SolidPeso molecular:224.34TyK2-IN-2
CAS:TyK2-IN-2 is a selective inhibitor of TYK2 (IC50s: 7 nM, 0.1 μM, and 0.05 μM for TYK2 JH2, IL-23, and IFNα).Fórmula:C16H18N6OPureza:98%Forma y color:SolidPeso molecular:310.35JAK1-IN-4
CAS:JAK1-IN-4 selectively blocks JAK1 (IC50 = 85 nM) over JAK2/JAK3 and halts STAT3 phosphorylation in NCI-H 1975 cells (IC50 = 227 nM).Fórmula:C26H32FN9O2Pureza:98%Forma y color:SolidPeso molecular:521.59TK4g
CAS:TK4g, a potent JAK inhibitor, has IC50s of 12.61 nM (JAK2) & 15.80 nM (JAK3); promising for lymphoid diseases & leukemia research.Fórmula:C19H19N3O4SForma y color:SolidPeso molecular:385.44γ-Secretase modulator 4
CAS:γ-Secretase modulator 4 is a potent γ-secretase modulator, reduces the Aβ42 level with IC50s of 0.017 μM and 0.014 μM in mouse and human, respectively.Fórmula:C23H19FN4O2Pureza:98%Forma y color:SolidPeso molecular:402.42Chromenone 1
CAS:Chromenone 1 is a potent potentiator of osteogenic bone morphogenetic protein (BMP).Fórmula:C18H10F3N3O2Pureza:99.83% - 99.93%Forma y color:SolidPeso molecular:357.29Ref: TM-T61301
1mg52,00€5mg111,00€1mL*10mM (DMSO)113,00€10mg162,00€25mg235,00€50mg330,00€100mg452,00€200mg607,00€Aβ42-IN-2
CAS:Aβ42-IN-2 is a γ-secretase modulator. Aβ42-IN-2 has an IC 50 of 6.5 nM for Αβ 42. Aβ42-IN-2 can be used for the Alzheimer's disease research[1].Fórmula:C24H26N6O2Pureza:98.09% - 99.87%Forma y color:SolidPeso molecular:430.5Ref: TM-T9641
1mg42,00€1mL*10mM (DMSO)93,00€5mg94,00€10mg134,00€25mg215,00€50mg304,00€100mg420,00€200mg582,00€JAK-IN-11
CAS:JAK-IN-11 (R-348) is a potent and selective inhibitor of JAK, has the potential for the skin disorders treatment.Fórmula:C23H22FN5O4SPureza:99.75%Forma y color:SolidPeso molecular:483.52OICR-0547
CAS:OICR-0547 is an inactive derivative of OICR-9429 and is commonly used as a negative control for OICR-9429.Fórmula:C28H29F3N4O4Pureza:98%Forma y color:SolidPeso molecular:542.55JAK-IN-21
CAS:JAK-IN-21 is a selective and potent JAK inhibitor that inhibits JAK1, JAK2, J2V617F and TYK2 with IC50 values of 1.73, 2.04, 109 and 62.9 nM, respectively.Fórmula:C19H16N8OPureza:99.87%Forma y color:SolidPeso molecular:372.38AF-2112
AF-2112, a TEAD inhibitor derived from Flufenamic acid, significantly diminishes the expression of CTGF, Cyr61, Axl, and NF2.
Fórmula:C21H18FNO3Pureza:98%Forma y color:SolidPeso molecular:351.37tCFA15
CAS:tCFA15: A trimethylated long-chain fatty alcohol with a 15-carbon side chain; may regulate Notch signaling and neuron differentiation.Fórmula:C24H44O2Pureza:98%Forma y color:SolidPeso molecular:364.61γ-secretase modulator 2
CAS:Gamma-secretase modulator 2 selectively targets Alzheimer's by reducing Aβ(1-42), aiding in prevention and treatment.Fórmula:C25H22F4N6O2Pureza:98%Forma y color:SolidPeso molecular:514.47JAK-IN-30
CAS:JAK-IN-30 (compound 31) is a water-soluble inhibitor of Janus kinases (JAKs), demonstrating inhibitory potency with half-maximal inhibitory concentration (IC50Fórmula:C19H26N8SPureza:98%Forma y color:SolidPeso molecular:398.53JAK-IN-28
CAS:JAK-IN-28 (Compound 111) is a Janus kinase (JAK) inhibitor potentially applicable in the research of cancer and inflammatory diseases [1].Fórmula:C20H18ClN7OPureza:98%Forma y color:SolidPeso molecular:407.86JAK-IN-18
CAS:"JAK-IN-18: potent JAK inhibitor for eye, skin, respiratory disease research (WO2018204238A1, comp 1)."Fórmula:C27H28F2N6O3Forma y color:SolidPeso molecular:522.55TEAD-IN-6
CAS:TEAD-IN-6 (Example 11-1) is a TEAD modulator that inhibits the YAP1/TAZ-TEAD interaction, and has applications in cancer research [1].Fórmula:C19H17F3N4O3SPureza:98%Forma y color:SolidPeso molecular:438.42LY-411575 isomer 1
CAS:LY-411575 isomer 1 is a potent γ-secretase inhibitor. LY-411575 isomer 1 is an isomer of LY411575.Fórmula:C26H23F2N3O4Pureza:98%Forma y color:SolidPeso molecular:479.48JAK3-IN-12
CAS:JAK3-IN-12 (compound 15k) is a potent inhibitor of JAK3 (IC50: 9.5 nM) and can be used in the study of rheumatoid arthritis.Fórmula:C19H19N5O4SForma y color:SolidPeso molecular:413.45
